KEGG   Bos taurus (cow): 526469
Entry
526469            CDS       T01008                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
bta  Bos taurus (cow)
Pathway
bta04010  MAPK signaling pathway
bta04012  ErbB signaling pathway
bta04620  Toll-like receptor signaling pathway
bta04664  Fc epsilon RI signaling pathway
bta04668  TNF signaling pathway
bta04912  GnRH signaling pathway
bta04926  Relaxin signaling pathway
bta04935  Growth hormone synthesis, secretion and action
bta04936  Alcoholic liver disease
bta05132  Salmonella infection
bta05135  Yersinia infection
bta05142  Chagas disease
bta05161  Hepatitis B
bta05166  Human T-cell leukemia virus 1 infection
bta05167  Kaposi sarcoma-associated herpesvirus infection
bta05169  Epstein-Barr virus infection
bta05208  Chemical carcinogenesis - reactive oxygen species
bta05417  Lipid and atherosclerosis
bta05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    526469 (MAP2K4)
   04012 ErbB signaling pathway
    526469 (MAP2K4)
   04668 TNF signaling pathway
    526469 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    526469 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    526469 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    526469 (MAP2K4)
   04926 Relaxin signaling pathway
    526469 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    526469 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    526469 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    526469 (MAP2K4)
   05161 Hepatitis B
    526469 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    526469 (MAP2K4)
   05169 Epstein-Barr virus infection
    526469 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    526469 (MAP2K4)
   05135 Yersinia infection
    526469 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    526469 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    526469 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    526469 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    526469 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bta01001]
    526469 (MAP2K4)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     526469 (MAP2K4)
Protein kinases [BR:bta01001]
 Serine/threonine kinases: STE group
  STE7 family
   526469 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 526469
NCBI-ProteinID: NP_001092508
BGD-bta: BT29145
Ensembl: ENSBTAG00000012103
VGNC: 31185
UniProt: A5PJP8
LinkDB
Position
19:30649006..30726941
AA seq 412 aa
MAAPSPSGGGGGGGGSGGGSGTPGPAGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLN
FANPPFKSTARFTLNPNPAGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGE
IGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGA
LFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIH
RDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVR
SDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLC
LTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1239 nt   +upstreamnt  +downstreamnt
atggcggctccgagccccagcggcggcggcggcggcggcggcggctccgggggcggcagc
ggcaccccgggccccgcggggtccccggcgcccggccacccggccgtcagcagcatgcag
ggctttcagataaacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaat
tttgcaaatccacctttcaaatctacagcaaggtttactctgaatcccaatcctgcagga
gttcaaaacccacacatagagagactgagaacacacagcattgagtcgtcaggaaaactg
aagatctcccctgagcagcactgggatttcactgcagaggatttgaaagaccttggagag
attggacgaggagcttacggttctgtcaacaaaatggtccacaaacccagtgggcaaata
atggcagttaaaagaatccggtcgacagtggatgaaaaagagcagaagcagctcctcatg
gatttggatgtagtgatgcggagcagtgactgcccatacattgttcagttctatggcgcg
ctcttccgagagggtgactgttggatctgcatggaactcatgtctacctcgtttgataag
ttttacaaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaa
atcactttagcaactgtgaaagcactaaaccacttaaaagaaaacttgaaaatcattcac
agagatatcaaaccttccaatattcttctggatagaagtggaaatattaaactctgtgac
tttggcatcagtggacagctcgtggactcgatcgctaagacaagagatgctggctgcagg
ccctacatggcacctgaaagaatagacccaagtgcgtcacgccaaggctacgacgtccgc
tctgatgtctggagtctggggatcacattgtacgaattggccactggccgctttccttat
ccaaagtggaatagtgtatttgatcaactaacacaagtcgtgaaaggggatccgccacag
ctgagtaactctgaggaaagggagttctccccaagtttcatcaactttgtcaacttgtgc
cttacgaaggatgaatccaaaaggccaaagtataaagaactcctgaaacacccctttatt
ttgatgtacgaggagcgcgccgtcgaggtcgcatgctacgtgtgtaaaatcctggatcaa
atgccagccaccccgagctcccccatgtatgtcgattga

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