Bos taurus (cow): 533233
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Entry
533233 CDS
T01008
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein
KO
K02085
adenomatosis polyposis coli protein
Organism
bta
Bos taurus (cow)
Pathway
bta04310
Wnt signaling pathway
bta04390
Hippo signaling pathway
bta04550
Signaling pathways regulating pluripotency of stem cells
bta04810
Regulation of actin cytoskeleton
bta04934
Cushing syndrome
bta05010
Alzheimer disease
bta05022
Pathways of neurodegeneration - multiple diseases
bta05165
Human papillomavirus infection
bta05200
Pathways in cancer
bta05206
MicroRNAs in cancer
bta05210
Colorectal cancer
bta05213
Endometrial cancer
bta05217
Basal cell carcinoma
bta05224
Breast cancer
bta05225
Hepatocellular carcinoma
bta05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
533233 (APC)
04390 Hippo signaling pathway
533233 (APC)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
533233 (APC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
533233 (APC)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
533233 (APC)
05206 MicroRNAs in cancer
533233 (APC)
09162 Cancer: specific types
05210 Colorectal cancer
533233 (APC)
05225 Hepatocellular carcinoma
533233 (APC)
05226 Gastric cancer
533233 (APC)
05217 Basal cell carcinoma
533233 (APC)
05213 Endometrial cancer
533233 (APC)
05224 Breast cancer
533233 (APC)
09172 Infectious disease: viral
05165 Human papillomavirus infection
533233 (APC)
09164 Neurodegenerative disease
05010 Alzheimer disease
533233 (APC)
05022 Pathways of neurodegeneration - multiple diseases
533233 (APC)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
533233 (APC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
bta01009
]
533233 (APC)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
bta03036
]
533233 (APC)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
bta04812
]
533233 (APC)
Protein phosphatases and associated proteins [BR:
bta01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
533233 (APC)
Chromosome and associated proteins [BR:
bta03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
533233 (APC)
Cytoskeleton proteins [BR:
bta04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
533233 (APC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_u14
APC_rep
APC_u15
APC_u9
APC_N_CC
SAMP
Arm
APC_u13
APC_15aa
Suppressor_APC
ARM_ARMC5
ZER1-like_2nd
Sec7-like_HUS
Motif
Other DBs
NCBI-GeneID:
533233
NCBI-ProteinID:
NP_001069454
BGD-bta:
BT18786
Ensembl:
ENSBTAG00000018852
VGNC:
55103
LinkDB
All DBs
Position
10:complement(1167671..1299376)
Genome browser
AA seq
2851 aa
AA seq
DB search
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR
RGFVNGSRENTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRITRIQQIEKDILRIRQLLQSQAT
EAERSSQSKHEAGSHEAERQNEGQGVAEINMATSGSGQGSTTRIDHETASVLSSSSTHSA
PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
WEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ
VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLQSESEDL
QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT
ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN
CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM
GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS
PKASHRSKQRHKQNLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS
LDSSRSEKDRSLERERGISLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS
QEDRSSGSTTELHCGTDERNALRRSSTTHTHANTYNFTKSENSNRTCPIPYAKVEYKRSS
NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE
LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHILEDEIKPNEQRQSRSQSTAYPVYPE
STDDKHLKFQPHFGQQECVSPYRSRAANGSETNRVGSNHGISQNVNQSLCQEDDYEDDKP
TNYSERYSEEGQHEEEERPTNYSIKYSEEKHHVDQPIDYSLKYTTDIPSSQKPAFSFSKN
SSGQSTKTEHISSSSENTSTTSSNAKRQNQLHPSSAQSRSGQTPKATSSSCKVPSINQET
IQTYCVEDTPICFSRCSSLSSLSSAEDEVGCDQTTQEAESANTLQIAEIKDNSGPRSNED
SVSKVPAGSQHIRTKSSRLQASGLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ
ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT
PPPPPPPPPQTVQTKQEVPKNKAPSAEKRESGPKQAAVNAAVQRVQVLPEADTLLHFATE
STPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPEESNENQEKEAE
KPTDSEKDLLDESDDDDIEILEECIISAMPTKSSRKAKKPAQTTSKLPPPVARKPSQLPV
YKLLPSQNRLQAQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEG
VRAGAQSSEFEKRDTIPTEGRSTDEAQRGKASSVTVPELDDSKTEEGDILAECINSAMPK
GKSHKPFRVKKIMDQVQQASMSSSGTNKNQLDGKTKKPTSPVKPIPQNTEYRTRVRKNTD
SKNNLNAERNFSENKDSKKQHLKNNSKDFNDKLPNNEDRVRGSFTFDSPHHYTPIEGTPY
CFSRNDSLSSLDFDDDDVDLSREKAELRKGKENKESEAKVTNHTELTSNQQSASKTPAVT
KQPINRGQSKPVLQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSRNSSLSSLSD
IDQENNNNKENEPVKETEPPASQGEPGKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSID
SEDDLLQECISSAMPKKKKPSRLKPDNEKHSPRNMGGILAEDLTLDLKDIQRPDSEHGLS
PDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPD
QEEKPFTSNKGPRILKPGEKSTLETKKIESENKGIKGGKKVYKSLITGKVRSNSEISSQM
KQPLQTNMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQPATTSPRG
TKPSVKSELSPVTRQASQTAGSNKGPSRSGSRDSTPSRPAQQPLSRPMQSPGRNSISPGR
NGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNGSGIPR
SESASKGLNQMSNSNGSNKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLR
RKLEESASFESLSPSSRPDSPTRSQAHTPVLSPSLPDMSLSTHSSLQSGGWRKLPPNLSP
TIEYNDGRPVKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSI
LSASSESSEKAKSEDEKQVNSISGSKQTKENQVSTKGTWRKIKESEISPTNSTSQTTSSG
AANGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDTVSEKGNPN
PKDSKDNQGKQNVSNGSAPTRTMGLENRLNSFIQVDPPDQKGTETKPGHSNNPVPASETS
ESSIAERTPFSSSSSSKHSSPSGTVAARVSPFNYNPSPRKSSTDGTSARPSQIPTPVSNN
TKKRDSKPDSTEPSGTQSPKRHSGSYLVTSV
NT seq
8556 nt
NT seq
+upstream
nt +downstream
nt
atggctgcagcttcatatgatcagttgttaaagcaagttgaggccctgaagatggagaac
tcaaatcttcgacaagagctagaagataattccaatcatcttacaaaactggaaactgag
gcatctaatatgaaggaagtacttaaacaactacaaggaagtattgaagatgaagctatg
gcttcttctggacagattgatttattagagcgtcttaaagaacttaacttagatagcagt
aatttccctggagtgaaactacggtccaaaatgtccctccgttcttacggaagccgagaa
ggatctgtatctagtcgctcaggagagtgcagtcctgttcctatgggttcatttccaaga
agagggtttgtaaatggaagcagagaaaataccggttatttagaagaacttgaaaaagag
agatcattgcttcttgctgaccttgacaaagaagaaaaggaaaaagactggtattatgct
caacttcagaatctcactaaaagaatagatagccttcctttaactgaaaatttttcctta
caaacagatatgaccagaaggcagttggaatatgaggcaaggcaaatcagagttgcaatg
gaagaacaactaggtacttgccaggatatggaaaaacgagcacagcgaagaataaccaga
attcaacaaatagaaaaggacatacttcgtatacgacagcttttacagtcccaagcaaca
gaagcagagaggtcatctcagagcaagcatgaagcgggctcacatgaagctgaacggcag
aatgaaggtcaaggagtggcagaaatcaacatggcaacctcgggtagcggtcagggttca
actacacgaatagatcatgaaacagccagtgttttgagttctagtagcacacattctgct
cctcgaaggctgacgagtcatctgggaaccaaggtggaaatggtgtattcattgttgtca
atgcttggtactcatgataaggatgatatgtcgcgaactttgctagctatgtctagctcc
caagacagctgtatatccatgcgacagtctggatgtcttcctctcctcatccagctttta
catggcaatgacaaagactctgtgttgttgggaaattcccggggcagtaaagaggctcgg
gccagggccagtgcagcactccacaacatcattcactcacagcctgatgacaagagaggc
aggcgtgaaatccgagtccttcatcttttggaacagatacgagcttactgtgaaacctgt
tgggagtggcaggaagcccatgaacaagggatggaccaggacaaaaatccaatgccagct
cctgttgaacatcagatctgccctgctgtctgtgttctaatgaagctttcgtttgatgaa
gagcatagacatgccatgaatgagcttgggggactacaggccattgcagaattattgcaa
gtggactgtgaaatgtatgggcttactaatgaccactacagtattactttaagacgatat
gcaggaatggctttgacaaacttgactttcggagatgtagccaacaaggctactctctgc
tctatgaaaggctgcatgagagcgctcgtggctcagctccagtctgaaagcgaggacttg
cagcaggttattgcgagtgttttgaggaatctgtcttggagagcagatgtaaatagtaaa
aagactttgcgtgaagttggaagtgtgaaagcattgatggaatgtgctttggaagtgaaa
aaggaatcaaccctcaaaagtgtattgagtgccttatggaacttgtcagcacactgcact
gagaataaagctgacatatgtgctgtggatggtgcgcttgcatttttggttggcactctc
acttatcgcagccagaccaatactttagccattattgaaagtggaggtggtatattacgg
aatgtatccagcttgatagctacaaatgaggaccacaggcaaatcctaagagagaataat
tgcttacagaccttattacaacacttgaaatctcacagtttgacaatagtcagcaatgca
tgcggaaccttgtggaatctctcagcaagaaaccctaaagaccaggaagcattgtgggac
atgggagcagtcagcatgctcaagaacctcattcattcaaagcacaagatgattgctatg
ggaagtgctgcagctttaaggaatctcatggcaaatagacctgcaaagtataaagatgcc
aatatcatgtctcctggttcaagtttgccttctctacatgtcaggaaacaaaaggccctg
gaagcagaattagatgctcagcatttatcagaaacttttgacaatattgacaatttaagt
cccaaggcatctcatcgtagcaagcagagacacaagcaaaatctctatggtgactatgtt
tttgacaccaatcgacatgatgataacaggtcagacaattttaatactggaaacatgact
gtcctatcaccgtacttaaacactacagtattgcccagctcttcttcatcaaggggaagt
ttagatagctctcgttctgagaaagatagaagtctggagagagaacgaggtattagccta
ggcaactatcacccagcaacagaaaacccaggaacctcttcaaagcgaggtttgcagatt
tctaccactgcagcccagattgccaaagtcatggaagaagtatcagctattcatacctct
caggaagacagaagttctgggtctaccacagaactacactgtgggacagatgagaggaat
gcactaagaagaagctctaccacccacacacatgcaaacacgtacaactttaccaagtca
gaaaactcaaacagaacatgtccaataccatatgccaaagtagaatataagagatcttca
aatgatagtttaaatagtgtcagcagtagtgatggttatggtaaaagaggtcagatgaaa
ccttcaattgaatcctattctgaagatgatgaaagtaaattttgcagctatggtcagtat
ccagctgacctagcccataaaatacatagtgcaaatcatatggatgataatgatggagaa
ctagatacaccaataaattacagtctcaaatattccgatgaacagttgaactctgggagg
cagagcccttcacagaatgaaagatgggcaagacccaaacatatactagaagatgaaata
aaaccgaatgagcagagacaatcaaggagtcaaagcacagcttatcccgtgtatcctgag
agcactgatgataaacacctcaagttccaaccacactttgggcagcaagaatgtgtttcc
ccatacaggtcaagagcagccaatggatctgaaacaaatcgagtaggctctaatcatgga
attagtcaaaatgtgaaccagtctttgtgtcaagaagatgactatgaagacgataaacca
accaactatagcgaacgttactctgaggaagggcagcatgaggaagaagagaggccaacc
aattatagcataaaatacagtgaagaaaaacatcacgtggatcagcctattgattatagt
ttaaaatacaccacagacattccttcttcacagaaaccagcattttcattctcaaagaat
tcatctggacagagcacaaaaactgaacacatctcttcaagcagcgagaatacatccaca
acttcatctaatgccaagaggcagaatcagctgcatccaagctcagcacagagcagaagt
ggtcagaccccaaaagccacctcttcctcttgcaaagtcccctctatcaaccaagaaaca
atacagacttactgtgtagaagataccccaatatgtttttcaagatgcagttcattatca
tctctgtcatctgctgaagatgaagtagggtgtgatcagacaacacaagaagcagagtct
gctaacactctgcaaatagctgaaatcaaggacaacagcggacctaggtcaaatgaagat
tctgtgagtaaagttccagcagggtcacagcacattagaaccaaatccagcagactccag
gcttctggtctgtcttcagagtcagccaggcacaaagctgttgaattttcttcaggggcc
aaatctccttccaagagcggtgctcagacacccaaaagtccaccagagcactacgttcag
gagaccccactcatgtttagcagatgtacttcagtcagttcactcgacagttttgagagt
cgctcgattgccagctctgttcagagtgaaccctgcagtggaatggtaagtggcatcata
agccccagtgacctcccagatagccctggacaaaccatgccaccaagcagaagcaaaacc
cctccgccgcctcctccacctcctcctcagacagttcaaacgaagcaggaagtacctaaa
aataaagcacctagtgctgaaaagagagaaagtggacccaagcaagctgctgtaaatgct
gcagtacaaagggtccaggttcttccagaggctgatactctgttacattttgccacagag
agtactcctgatggattttcttgttcatctagcctgagcgctctgagccttgatgagcca
tttattcagaaagatgtggaactaagaataatgcctccagttcaggaaaatgacaacggg
aatgaaacagaaagtgagcagcctgaagaatcaaatgaaaaccaggaaaaagaggcagaa
aaacccactgattctgaaaaagatcttttagatgagtcagatgatgatgatattgaaata
ctagaagagtgtataatttctgccatgccaacaaaatcttcacgcaaagccaaaaaacca
gcccagactacttcaaaattacctccacctgtggcaaggaaaccaagtcagctccctgta
tacaaacttctgccatcgcaaaacaggttacaggcacaaaagcatgttagttttacacca
ggagatgatatgccacgggtgtattgtgtagaagggacacctataaacttttccacagct
acatctctgagtgatctaacgatagaatcccctccaaatgagttagctgctggagaaggg
gttagagcaggggcacagtcaagtgagtttgaaaaacgagataccattcctactgaaggc
agaagtacagatgaggctcaacgagggaaagcctcatctgtcactgtgcctgaactggac
gacagcaaaacagaagaaggtgatattcttgcagaatgcattaattctgccatgcccaaa
ggaaaaagtcacaagcctttccgtgtgaaaaagatcatggaccaggtccagcaagcatct
atgtcttcatctggaactaacaaaaatcaattagatggtaagacgaagaaacctacttca
ccagtaaaacctataccacaaaatactgaatacaggacacgtgtaagaaaaaatacagac
tcaaaaaataatctaaatgcagaaagaaatttctcggaaaacaaagactcaaagaaacag
cacttgaaaaataattccaaggacttcaatgataaactgccaaataatgaagacagagtc
agaggaagttttacttttgattcaccccatcattacacgcccattgaaggcactccgtac
tgtttttcacgaaatgactctctgagttctctagattttgatgatgatgatgttgacctt
tccagggaaaaggctgaattaagaaaggggaaggaaaataaagaatcagaagctaaagtg
accaaccacacagaactaacctcaaaccaacaatcagctagtaagacaccagctgttaca
aagcagccaataaatagaggtcagtctaaacccgtgctgcagaagcagtccacttttccc
cagtcttccaaagatataccagacagaggggcagcaacagatgagaaattacagaatttc
gctattgaaaatactccagtttgcttttctcgaaattcctctctaagctctcttagtgac
attgatcaagaaaacaacaacaacaaggaaaatgaacctgtcaaagagacagagccccct
gcctcacagggagaaccaggtaaaccccaggcctcaggttatgctcctaaatcgtttcac
gtggaagacacccctgtttgtttctcaagaaacagttctctcagttctcttagtattgat
tctgaagatgacctgctgcaggaatgtataagttctgcaatgccaaaaaagaaaaagcct
tcaaggctcaagcccgataatgaaaagcatagtcccagaaatatgggtggcatattagca
gaagatttgacactcgatttgaaagatatacagagaccagattcagaacatggtttatcc
ccagattcagaaaattttgattggaaagctattcaggaaggtgcaaattccatagtaagt
agtttacatcaagctgctgccgctgcatgtttatctcgacaagcttcatctgattcagat
tctatcctttcattgaaatcgggtatctctctgggatcaccatttcaccttacacctgat
caagaagaaaaaccctttacgagtaataaaggtccacgaattctaaaacctggggagaaa
agtacattggaaactaaaaaaatagaatctgaaaataaaggaataaaaggaggcaaaaag
gtttataaaagtttgattactggaaaagttcgatctaattcggaaatttcgagccaaatg
aaacaaccccttcaaacaaacatgccttcaatctctcgaggtaggacaatgattcatatt
ccaggagttcggaatagctcttcaagtacaagcccagtttctaaaaaaggcccgcccctc
aagactccagcctccaaaagccctagtgaaggtcagccggctaccacctctcccagagga
accaagccatcagtgaagtcagaattaagccctgttacaaggcaggcatcccagacagca
ggatcaaacaaaggaccttctagatcaggatctagagattccactccttcaagacctgcc
cagcaaccattaagtagaccaatgcagtctccagggcgaaactcaatctctcctggtaga
aatggaataagtccccctaacaaattatctcaactaccaaggacgtcatcccctagtact
gcttcaactaagtcctcaggttctgggaaaatgtcttacacatctcctggcagacagatg
agccagcagaacctcaccaaacaaacaggcttatccaagaatggcagtggtatcccaaga
agtgaatctgcctccaaagggctaaatcaaatgagtaatagtaatggatccaataaaaaa
gtagaactttctagaatgtcttcaacaaagtcaagtggaagtgaatccgataggtcagag
agacctgtattagtacgccaatcaactttcatcaaagaagctccaagcccaaccctaagg
agaaaactggaggaatctgcttcatttgaatctctttctccatcttccagacccgattct
cccacacggtcccaggctcatactccagttttaagtccttcccttcctgatatgtctcta
tctacacattcgtctcttcagtctggtggatggcgaaaactcccacctaacctcagtccc
accatagagtataatgatggaagaccagtaaagcgccatgatatagcacgctctcattcc
gaaagtccttccagacttcccatcaataggtcagggacctggaaacgtgagcacagcaaa
cactcatcatcacttcctcgagtaagcacttggagaagaactggaagttcatcctcaatt
ctttctgcttcatcagaatctagtgaaaaggcaaaaagtgaggacgaaaaacaagtgaac
tctatttcaggaagcaaacaaactaaagaaaaccaggtatccacaaaaggaacatggaga
aaaataaaagaaagtgaaatttctcccacaaatagtacttctcagaccacttcttcaggt
gctgcaaatggtgctgaatcaaagactctgatttatcaaatggcacctgctgtttctaaa
acagaggatgtttgggtgagaattgaggattgccccattaacaaccctagatctggaaga
tctccaacaggaaatactccccccgtgattgacactgtttcagaaaagggaaacccgaac
cctaaagattcaaaagataatcagggaaaacaaaatgtgagcaatggtagtgcccctaca
cgcaccatgggtctggaaaaccgcctgaattcctttattcaggtagatcctccagaccaa
aaaggaactgagacaaaaccgggacacagtaataaccctgtccctgcatccgagactagt
gaaagttctatagccgagcgtaccccgtttagttctagcagctcaagcaagcacagttca
ccaagtgggactgtcgccgccagggtgagtccttttaattacaacccaagcccaaggaag
agcagcacagatggcacttcagcccgaccgtctcagatcccaacgccagtgagcaacaac
acaaagaaacgcgactcaaaacccgacagcacagaacccagcgggactcaaagtcctaaa
cgccattctgggtcttaccttgtgacatctgtgtga
DBGET
integrated database retrieval system
