Bos taurus (cow): 533440 Help Entry 533440            CDS       T01008                                  Symbol TSC1 Name (RefSeq) hamartin isoform X1   KO K07206   tuberous sclerosis 1 Organism bta  Bos taurus (cow) Pathway bta04072   Phospholipase D signaling pathway bta04140   Autophagy - animal bta04150   mTOR signaling pathway bta04151   PI3K-Akt signaling pathway bta04152   AMPK signaling pathway bta04211   Longevity regulating pathway bta04218   Cellular senescence bta04714   Thermogenesis bta04910   Insulin signaling pathway bta05163   Human cytomegalovirus infection bta05165   Human papillomavirus infection bta05168   Herpes simplex virus 1 infection bta05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     533440 (TSC1)    04151 PI3K-Akt signaling pathway     533440 (TSC1)    04152 AMPK signaling pathway     533440 (TSC1)    04150 mTOR signaling pathway     533440 (TSC1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     533440 (TSC1)   09143 Cell growth and death    04218 Cellular senescence     533440 (TSC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     533440 (TSC1)   09149 Aging    04211 Longevity regulating pathway     533440 (TSC1)   09159 Environmental adaptation    04714 Thermogenesis     533440 (TSC1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     533440 (TSC1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     533440 (TSC1)    05163 Human cytomegalovirus infection     533440 (TSC1)    05165 Human papillomavirus infection     533440 (TSC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  533440 NCBI-ProteinID:  XP_010808830 BGD-bta:  BT14906 Ensembl:  ENSBTAG00000005190 VGNC:  36407 LinkDB All DBs Position 11:complement(102923420..102975515) Genome browser AA seq 1159 aa AA seqDB search MAQQANIGELLSMLDSPLLSVRDDVTTVFKENLNSDRGPMLVNTLVDYYLETNSQPVLHI LTTLQEPHDKHLLDKMNEYVGKAASRLSALLLLGHVVRLQPSWKHKLSQAPLLPSLLKCL KMDTDVIVLTTGVLVLITMLPMIPQSGKQHLHDFFDIFGRLSSWCLKKPGHVTEVYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVSASSYVDT QNSYGNATSTPYSTSRLTLNTPGQLPQTLSSPSTRLLAEPPQATLWSPSAVCGMTTPPTS PGNVPPDLSHPYSKVFGTTGGKGTPLGTPATSPPPAPPCHSDDCVHLSLPQATAPKKEER TDSARPCLHRQPHVPNDRGLEELHGGKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISK ELSEITTADAEPLVPRGGFDSPFYRDSLPGCPRKTLSASSSTQGTSANPEPLNSSLDKSG PDTPKQAFTPIDLPCGGTGESPAGNRERQASLEASILTPSPCKIPPQRGVGFGSGQPPPY DHLFEVALPKTAHHFVSKKTEELLKKAKGSAEEDFTPSASPMEVLDRLIQQGADVHSKEL NRLSLPSKSVDWTHFGGSPPSDEICTLRNQLLLLHNQLLYERFKRQQHALRNRRLLRKVI RASALEEHNAAMKDQLKLQEKDIQIWKISLQKEQARYNQLQEQRDTVVTQLHSQIRQLQH DREEFYNQSQELQTKLEDCRNMIAELRVELKKANSKVCHTELLLSQVSQKLSNSESVQQQ MEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQNQRLDT CQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILD LYGKLEKDGLLKKLEEQKPEAAEAAEERLDYCQDGCSDSVTGHNEEAPGRNGETKPSRPG GARGGGGGGGRGGGSSSELSTPEKPPNPRAGPFSSRWETVVGEPTSGTPTTVGSLPSSES FLGMKARELFRNKSESQCDEDGLTVGSLSETLKTELGKDSGVEARAPLTLDGPLLPAPKP DSVGQLRIMDYNEAQLEHS NT seq 3480 nt NT seq  +upstreamnt  +downstreamnt atggcccagcaagccaatattggggagctcctctccatgctggactcccctctgctgagt gtgcgtgatgatgtaacaactgtctttaaagagaatctcaattctgaccgtggtcctatg cttgtgaacaccctggtggattattatctggaaaccaactctcagcctgtattgcacatc ctgactaccttgcaagagccccatgataagcacctcttggacaaaatgaatgaatacgtg ggcaaggccgcctctcggttatccgccctcttgctactgggccacgtcgtgaggctgcag ccgtcatggaagcataagctctctcaagcacctcttttgccttctctactaaaatgtctc aagatggacaccgacgtcattgtcctcacaacaggagtcttagtgttgataaccatgctc ccaatgattccgcagtcggggaaacagcaccttcatgatttctttgatatctttggccgt ctttcgtcatggtgcctgaagaaaccaggccatgtgacagaagtctatctcgtccacctc cacgccagcgtctacgctctcttccatcgcctgtatgggatgtacccttgcaactttgtc tcctttctgcgttctcactacagtatgaaggaaaacctggagacttttgaagaagtggtc aagccaatgatggagcatgtgcgaattcacccggaattagtgactggatccaaggaccat gaactggaccctcgaaggtggaagagattagaaacacatgatgttgtcatagaatgtgcc aaaatctctctggaccctacagaggcctcatatgaagatggctattctgtgtctcaccaa atctcagcccgttttcctcaccgttcagccgatgtctccgccagctcttacgttgacaca cagaatagctatgggaatgctacttctaccccctactctacttctcggctgacgttaaac acgccagggcagctacctcagactctgagttccccgtcgacacggctattagctgagccg ccacaagctactctttggagcccatctgcagtttgtgggatgaccactcctccaacttct cctggaaatgtcccacctgatctgtcacatccttacagtaaagtctttggtacaactggt gggaaaggaactcctctgggaacccctgcaacctctcctcctccagccccaccctgccat tcggacgactgcgtgcacctttcactcccacaggccacggcccccaagaaggaagagagg acagactccgcaaggccctgtctacacagacaaccccatgttccgaatgacagaggatta gaagagctgcacggaggcaagggatctgtcactctcagtgatcttccagggtttttagga gacctggcttctgaagaagacagtattgagaaggataaagaagaagcggccatatctaaa gagctgtctgagatcacgacggccgatgccgagcccctggttcctcgaggaggcttcgac tcacccttctaccgggacagtctgccgggctgcccgcggaagaccctctcagcttcctcc agcactcagggcaccagcgcgaaccctgagcctttaaactcctccctggacaagtcgggg cctgacacaccaaagcaagccttcacgcccatagacctgccctgcggaggcaccggggag agccctgccgggaacagggagcgccaggcctctctggaggccagcatcctcacccccagc ccctgtaaaattccacctcagaggggagtggggtttggcagtgggcagcctcccccatac gatcatctttttgaggtggcattgccaaagactgcccatcattttgtcagcaagaagacg gaggaactgctcaagaaggcaaagggaagtgcagaggaggacttcacgccctccgcctcc cctatggaagtgctggacaggctgatacagcagggagcggacgtgcacagcaaggagctc aacaggttgtctttacccagcaagtctgtcgactggacccacttcggaggctctcctccc tcagatgagatctgcaccctccgtaaccagttgcttttactgcacaaccagttactctac gagcgtttcaagcggcagcagcacgcgctgcgcaacaggcggctcctgcgcaaggtgatc cgggcctcggctctggaggagcacaacgccgccatgaaagaccagttgaagttgcaagag aaagacatccagatatggaagattagtctgcagaaagaacaagccaggtacaatcagctt caggagcagcgagacacagtggtcacccagcttcatagccagatcagacagcttcagcac gaccgggaggagttctacaaccagagccaggagttacagacgaagctggaggactgcagg aacatgatcgcagagctgcgcgtggagctgaagaaggccaacagcaaggtgtgccacacc gagctgctgctcagccaggtgtcccagaagctctcaaatagtgagtcggtccaacagcag atggagttcttgaacaggcaactgttggttcttggggaagtcaacgagctgtatttggaa cagctgcagaacaagcattcagacaccaccaaggaagtagaaatgatgaaggctgcatat cggaaagagctagaaaaaaacagaagccacgtcctccagcagaatcagaggcttgatacc tgtcagaagcggattttggaactggaatctcatctggctaagaaagaccaccttctttta gaacagaaaaagtatctagaggatgtcaaactgcaggcaagaggacagctacaggctgca gagagcaggtatgaggcccaaaagaggatcacccaggtgtttgaattggagatcttagat ttatacggcaagttggagaaggatggcctcctgaaaaaacttgaagaacaaaaaccagaa gcagctgaagcagcagaagaaaggcttgactactgtcaggacggctgctcggattcggtg acagggcacaacgaagaggcccctggccgtaacggtgagaccaagccctccaggcctggc ggcgcccggggcggtggcggtggcggcggcagaggtggcggcagcagcagcgagctctcc accccggagaagccccccaaccccagggcgggcccgttcagcagtcggtgggagacggtg gtgggtgagcccacttccggcacccccacgacggtgggctcgcttcccagctcagagagc ttcctgggcatgaaggcacgagagctgtttcgtaacaagagcgagagccaatgcgacgag gatggcctgactgttggcagcctttctgagaccctaaagacagagctgggcaaagactcg ggtgtggaagccagggcccccctgacccttgatggcccactgctgcctgccccaaagccg gacagcgtgggccagctccgcatcatggactacaacgaggcccagcttgagcacagctag

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