Bos taurus (cow): 534284
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Entry
534284 CDS
T01008
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
bta
Bos taurus (cow)
Pathway
bta05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
534284 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
bta03021
]
534284 (SETX)
Enzymes [BR:
bta01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
534284 (SETX)
5.6.2.5 RNA 5'-3' helicase
534284 (SETX)
Transcription machinery [BR:
bta03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
534284 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
ResIII
Helicase_RecD
SLFN-g3_helicase
nSTAND3
UvrD_C_2
AAA_16
Motif
Other DBs
NCBI-GeneID:
534284
NCBI-ProteinID:
XP_010808825
Ensembl:
ENSBTAG00000024822
VGNC:
34501
UniProt:
E1BAS6
LinkDB
All DBs
Position
11:complement(102335399..102427001)
Genome browser
AA seq
2683 aa
AA seq
DB search
MVPSSKNADEINKTAFQKKCRMSTCCWCTPGGTSTTDFLQRYASRTHSSEFQTADEDLCY
CLECVAEYHKARDELPFLHEVLWELETLRLINHFERSMKAEIGDDDELYIVDNNGEAQLF
DFTGQDFENKLRVPLLEILKYPYLLLHEHVNELCVEALCRMEQANCSFQVFDKHPGIYLF
LVHPNEMVRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLLENPDIYTSSVLEKG
KLVLLPSHMYDTANYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSN
DNSVDPFWPALHCFMVILDRLGSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSVRTK
LEPESYLDDMVTCSQIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQ
DMRVHNSTFLWFIPFVQSLMDLKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFL
LILVSVIELHRNKKCLHLLWVSSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMIS
SLSLHSMPSNSVQLACVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQ
ETHELQTCLKQIIRNIKFKVPQCSTFVDLNPACKMPPASYKEESEQIGKKSEKDVHCLEN
SSPTSSKEPMKADAYQVQESILSKANNAIEESKEPYYIKDLKLEGHLSAESCLKLSSKNL
ACERVQNQVKISTGKYKSVKENSSCTPQNGTLRNGPEKVFDRGIIISRRLLTVSSTDSLE
KVSASDEDFSLKEDGLGKSSKAKSKTHKDGVCAKLSHVIKKQRRRSISLEENLTVSSIEG
FYSKKDLGGQKGGGNICNPSLVPNGILDDKNGEQKSQSCLLLKKKEVKKEKLDLFSTPEN
SCQIQECHVDSKDLVSLTEMTSICMTNASPFKEPVTGHELRDRKISRSTDQFSSNLREQD
LSSSPQPDTLTDSQVDRDLHKLSLIAQASVTKFPSDSTEKSLSQIQRKVKDEKRCFTANQ
NVRETCCGQVIIISDSDDDEDEERILGLKKQMREVKACIEKECPEQHTSIANTNVEQKVL
IKEENPVSLLEFEESDSQFFEFETPCEVFSVWHDQKPDKNSAQENEKNPCSTHVGDSAND
LGYETDYVPEEVIKKVAENFEERTKPRSSSTSVEEFCEIEVKKPKRRRYEKPIAEDPLRP
SSSSVKNEDQSDILNKGNLSKNDFKGVDARSTVPSSSVQRNTVVSPKKSLPKPRMYSKPV
RKVPVVKASKKSHSDTKKGQSKSSHYISCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAP
RRAFELSQRSLECIVQLRDHGKTVGVVDTRKKTKLISPQTLSVRNNKKLLTSQDLQLQRQ
MRSKSQQNRQRFDCRSTDTTRAGPRAAQSSAVPESSKSDYSHGGAEVTANNKGKQLLTCQ
SSETEPVKANQCNPVIVNGRIATNEVIVPTSEDLLDRGDLTVHHLEVATLKEGEPQFSSD
IEEDDIFLTQRDPEDMDLCSQIERENDKLIEVIHGKDTVQGEEECVSQPQLESLSSTKCK
YKDCVETLKNPGEYCSKHSKTKATDEDVFRKPGLPLSASKRSRPSTTKVFSSSSTSRIAG
LSKSLESTAALPSSLKNKSSGAQSVLKGPQPPLTVSLKPVAEVKGLCNVFPAQTPNNSNR
QVLRVPFGESRPFLTSSPVNILTSSQSISDTFVKEVLKWRYEMFVNFDQCGPPSSLCQSI
ERRVPIRFQDCGDYFNVFFPLMVLNTFETVAQEWISSPNKEKFHQLHLRKFPGDYKKYWE
FVVYLEECELAKQLHPRENDLVFLVPERLNEEKKDLEWSHLEDACEYYCGYVHKFRRTSV
MHNGKFECSVSIQTQDNLPVNLNELVKCFVISSLVTTQRKLKAMSLLSGRNQLARAILNP
NPMDFCTKDLPTATSERIVAYLKDFNEDQKKAIETACAMVKHSPSVAKICLIHGPPGTGK
SKTIVGILYRLLTENQRRGYSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCK
DKKNPMGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQEMHKRKEFLDH
QLDELSRQRALCRGGRESQRQELDGKIARVSKERQELASKIKEVQGRPQKTQSIIILESH
IICCTLSTSGGLLLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLVLVGDPK
QLPPTVISVKAQDYGYDQSMMARFHKLLEESVEHNMIGRLPVLQLTIQYRMHPDICLFPS
SYIYDGILRTNRGTETSRCSSDWPFQPYLVFDVGDGLERRDNDSYVNVQEIKLVMELIKL
IKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGAAEVDTVDAFQGRQKDCVIVTC
VRANATQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLVENRHWYHLIQDAQKRGAIIK
TCDKNYRHDAMKILKLKPLLQRSLTHPPAVAPEASRPQGGLPSSKQDGELSKTSFASSLY
HSPSDSKEATVTEAAKDPERPPNQDWLRDPRLLRRMGLALDAQGISLREPQPLSPQHSGA
APPLGTPGCPGSPQEPGTIRQQGVTLNNHTPHMQCDSPVASTDTSTSKKKCDQEEGVLSH
RRETRSLSVGDQEWWASSHAKRNSDWDERVLEEDSCSKKRRVL
NT seq
8052 nt
NT seq
+upstream
nt +downstream
nt
atggttcccagcagtaaaaacgctgatgaaattaacaaaactgccttccagaagaagtgc
agaatgagtacatgttgttggtgtaccccaggtggtacttccaccactgacttcctacaa
cgctatgcatccaggacccactccagtgaatttcagacagctgatgaagacctctgctac
tgcttggagtgtgtggctgaataccacaaagcaagggacgaattgccgttcttacatgag
gttttatgggaattagaaaccttacgtctcataaatcactttgaaagatccatgaaggca
gaaattggagatgatgatgagttatatatagtagacaacaacggagaggcacagctgttc
gatttcactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaa
tatccatatctgcttttacatgagcatgtcaatgaattatgtgttgaagcactttgccgg
atggaacaagctaattgctcctttcaagtttttgacaaacatccagggatctatttattt
ttggttcatcccaatgaaatggttcggcgttgggctatcctgactgcaagaaacttgggg
aaagtggatagagatgattactatgacttacaggaggttttgacttgcctttttaaagtt
attgagttgggacttttagaaaacccagacatttatacttcttctgtccttgagaagggt
aaactggttcttctgccttcacacatgtatgatactgccaactacaaaaactattggtta
ggtatctgtatgctgctgaccattcttgaagagcaagccatggattcactgttgttgggc
tcagataaacagaatgattttatgcagtcaatacttcacaccatggagaggcaatcaaat
gataatagtgtggatcctttctggccagcattacactgtttcatggtgattctggatcgc
cttggatctaaggtctggggtcaacttattgatcctattgaagcatttcaaaccattatt
aacaacgtgagctacaatagagagatccagaacatacggaacagctctgtgaggaccaag
ttagaaccggagtcatatttggatgatatggtgacttgcagccagattgtatacaattat
aatcctgaaaagaccaaaaaggattcggggtggagatcagccatttgccctgattattgt
cctaacatgtatgaagaaatggaaacattagctaacgtgctccagtcagacattggtcag
gacatgcgtgttcataacagcacatttctgtggttcatccctttcgtgcaatccctcatg
gacctgaaggatctgggtgtggcttacatagtggaggttattcaccatctgtactctgaa
gtcaaagatgttctcaaccagacagacgctgtgtgtgacaaagtcactgagtttttcctt
ctgattttggtgtctgtgattgaactgcatagaaataaaaaatgtctacatttgctgtgg
gttagttcccagcagtgggtggaggctgtggtgaagtgtgccaagctcccaaccacagcg
tttgcacggagttctgagaagtcatctggaaactgttccaaaggcacagcaatgatatca
tccctgtcactgcattcaatgccctccaactctgtgcagctggcttgtgtgcagctgatt
agaagtctcctgaaagaaggctatcagcttgggcagcagactctctgtaagcggttctgg
gataagctcaacttattcctgcgagggaatttatctttaggttggcagttgactagtcag
gaaacccatgagctacaaacttgtttaaagcaaattattaggaacataaaatttaaagta
cctcagtgtagcacttttgtggatctgaatcctgcatgtaagatgcctcctgcatcttat
aaagaagaaagtgaacaaatagggaagaagtctgaaaaagatgtgcactgtctagaaaat
tccagcccaacatcttctaaagaaccaatgaaagctgatgcatatcaagtgcaagagagt
attttgagcaaagcaaacaatgccatagaagagagtaaagagccatattatataaaagat
ttgaaactagaaggccacctctcagctgagtcatgtttgaaactgagtagtaaaaacctt
gcctgtgaaagagttcaaaatcaagttaaaataagtacagggaaatacaagtctgtaaaa
gagaattcctcatgtaccccacagaatggtactttaagaaatggtccagaaaaagtattt
gacagaggaataataatatcaaggcgcttattgactgtttctagcacggattctctggaa
aaagtgtctgcctccgatgaggacttctcgttaaaggaagatggtcttggcaaaagctca
aaagcaaaatctaagacacataaagatggagtctgtgctaagttgtcacatgtaataaaa
aagcaacgcaggagaagtatcagtttagaggaaaacctgactgtatctagcattgagggt
ttctattcaaagaaagatctaggaggtcagaaaggaggtggaaacatatgcaatccttct
ttagtccctaatggtattctggatgataaaaatggagaacaaaaatctcaaagctgttta
ctgctgaaaaagaaagaagtaaagaaagaaaagttagatcttttctctacccctgaaaac
agttgtcaaatacaggaatgtcatgttgatagcaaagatttggtctcactcacagaaatg
accagtatctgcatgacgaatgcatctccctttaaagagcctgtgactggacatgaattg
agagataggaaaattagtaggagcactgatcagttttcttctaatttaagagaacaggac
cttagcagcagtccccagcctgacaccttaacagattctcaggtagatagagacctccac
aaattatctttaatagctcaagccagtgttactaagttcccatcagattcaactgaaaaa
agtttatcccaaatacaaagaaaagtaaaagatgagaaaagatgtttcacggcaaaccaa
aatgtcagggaaacctgctgtggacaggttattattatttcagattccgatgacgatgaa
gatgaggaaagaattctgggtttgaagaaacaaatgagagaggtcaaagcatgcattgag
aaagaatgtccagagcaacatacttcaatagctaacacaaatgtggaacagaaggtatta
ataaaggaagaaaatccagtgtcccttttggagtttgaggaatctgattctcagtttttt
gagtttgagactccatgtgaagtgttttcagtttggcatgatcagaaaccagacaagaat
tcagctcaagagaatgaaaaaaatccatgctcgactcatgtgggtgatagtgcaaatgat
ttgggttatgagacagattatgtgcctgaagaggtcattaaaaaagtagcagagaacttt
gaagagcgcacaaaaccacgtagtagtagtacttctgttgaggaattttgtgaaattgaa
gtaaaaaaacccaagagaagacggtatgaaaaacctatagctgaagatcctctaaggcct
tcttcatcttctgttaaaaatgaggaccagtctgatattcttaacaagggaaatctgagt
aaaaatgattttaaaggtgtagacgcaagatctacagttcccagttcaagtgttcagaga
aacactgtggtttccccaaagaagtctcttccaaagcctcgcatgtattccaaacctgtc
aggaaagttccagtggttaaagcttctaagaaatcccattcagataccaagaaagggcag
agtaaaagctcccattacataagttgtagaacaactcctgctattgtgccgccaaagaaa
tttcgccagtgtcccgaaccaacttcaacggttgagaaacttggcctgaaaaaggctcct
cgtagggcatttgaattgtcccagcgatctttagagtgtatagttcagctccgtgaccat
ggcaaaactgttggagtagtggatacccggaaaaagacgaagttaatttctcctcagact
ctctctgtcagaaataataagaaactgctgacgagtcaagaccttcagttgcaaaggcag
atgagatccaaatcacaacaaaacagacaacgttttgattgtcgaagtacagatacaaca
cgagcagggccacgtgctgcacagagctctgctgtgccagaatcaagtaagtcagattac
agtcatggaggagccgaggtgactgctaacaataagggaaaacagttactaacatgtcag
tcttctgaaacagaacccgtgaaagcaaaccagtgtaatcctgtcatagtaaatggaaga
atagcaacaaatgaagtcattgttcctacctcagaggacctgttagacagaggtgaccta
acagttcatcatttagaggtggcgactttgaaagagggagagcctcaattcagcagtgac
atagaggaagatgatatattcttaacacagcgtgaccctgaagacatggatttatgttca
caaatcgagagagagaatgataaactcattgaagtcattcatggaaaagatacagtgcag
ggagaggaagaatgtgtgagtcagcctcagttggaatctttgagtagcacaaaatgtaag
tacaaagattgtgttgaaactctgaaaaacccaggtgagtactgctcaaaacactcaaaa
actaaagccacagatgaagatgtattccgtaaacctggcttgcctctgtctgcatcaaaa
cgttcgagaccttccacgaccaaggtttttagttcaagcagtacttcacggattgctggt
ctctccaagtctttggaaagtaccgcagccctcccatcatctctgaaaaataagtcaagt
ggggcacagtctgttcttaaaggaccacagccaccccttacggtgtctctgaagccagtg
gctgaagtgaaaggtctgtgcaatgttttccctgctcagactccaaataactccaacagg
caagttctgagagttccatttggggaaagcagaccttttttgacttcctctccagtaaac
attctcacgtcgtcacagtccatctctgatacttttgtaaaagaggtcttgaaatggaga
tatgagatgtttgtgaactttgatcagtgtgggcccccgtcgagtctgtgtcagtccatc
gaaagacgggtgcctatcaggtttcaagactgtggagattattttaatgtgtttttccct
ttgatggtcctgaatacttttgaaacagtggcacaggaatggatcagctctccaaacaaa
gagaaattccatcagttacatttacgaaaatttcctggtgattataaaaaatactgggag
tttgtggtttatcttgaggaatgtgagctagctaaacagcttcatccaagggaaaatgat
ttggtgtttttggttcctgaaagactcaatgaggagaagaaagatttagagtggagtcac
ctggaggatgcctgtgaatattattgtggctatgttcataaattccgtcgtacttcagtc
atgcataatgggaaatttgagtgttcggtttccatccagactcaagataatttaccagtc
aatttaaatgaactcgtgaaatgctttgtaatcagctctctggtgactacacaaaggaag
ttgaaagccatgtctttgctgagtggtcggaaccaactggccagagccattctgaatcca
aaccccatggacttctgtacaaaagatttaccaactgcaacatctgagagaattgttgcc
tacttaaaagatttcaatgaagaccagaagaaagcgatagaaactgcatgtgccatggtg
aaacactccccatcagttgccaagatctgtctgattcatggaccacctggaacaggaaaa
tcaaaaaccattgttggcatcctgtaccgcctgctgacagagaaccagaggagggggtat
tcagatgaaaactccaacgccaaaatcaagcaaaaccgtgtcctcgtatgtgctccttcc
aatgcagctgttgatgaacttatgaaaaaaattatccttgaattcaaagaaaagtgtaaa
gacaagaagaatcctatgggaaactgtggagatataaatttagtacgtctaggtccagaa
aagtctattaataatgaggtcctgaaattcagtttggacagtcaagttaaccacagaatg
aaaaaagacttaccgtctcatgttcaggagatgcacaaaagaaaggaatttcttgatcat
caacttgatgaactttcccgccagcgtgctttatgccgaggtggaagggaatcgcagagg
caagaattagatggaaaaattgccagagtttcaaaagaaaggcaggagcttgcttctaaa
attaaagaggttcaaggacgcccacagaagacacagagcatcatcatcttagagtcacac
atcatttgctgcaccctgagcacgagtggtggcttgctgctcgaggctgctttccgtggg
caaggaggcgtccccttcagctgtgtcatcgttgatgaggctggacagtcttgtgaagtt
gaaactcttactccgctcatccatcgttgcaacaagcttgtcctcgtaggagaccctaag
cagctccctcccacagtcatttccgtgaaggcacaggactacggctatgaccagtcgatg
atggcccgcttccacaagctcctggaggagagtgtggagcacaacatgattggcaggctg
cccgtcttacagctcaccatccagtacaggatgcacccggacatatgcctctttccttct
agttatatttatgatggaatcttgagaacaaatagagggacagagaccagtcggtgttca
tctgactggccatttcaaccctacctcgtgtttgatgttggagatggcttagaaagacgg
gataatgactcatatgtaaatgttcaagagataaaactggtaatggaactaattaaactt
attaaagacaaacgaagggacgttactttccgaaacattggcataataacccattacaag
gctcagaagacaatgattcagaaggatttggacaaagagtttgatagaaaaggggcagca
gaagtcgataccgtggatgccttccaggggcgtcagaaagactgtgttattgttacatgc
gtcagagcaaatgccacacaaggctcaattggatttctggcaagtttgcagagattgaat
gtcaccatcacacgagccaagtacagcctcttcatcctcggacacttgagaaccctagtg
gaaaatagacattggtatcacctgattcaagatgcacagaaacgtggcgccattattaag
acttgtgacaagaactacagacacgatgcaatgaagatcctgaagctcaaaccattgctt
caaaggagccttactcaccctcctgctgtcgctccagaggcatccagaccccagggtggc
ctacccagcagcaagcaagatggtgaactcagcaagacatcttttgcttcttccctatac
cactcaccctctgactccaaagaagccacagtcactgaggctgcaaaggatcctgaaagg
ccacccaatcaggactggcttcgggacccaagactgctgcggaggatgggcttggccttg
gatgcccaaggaataagcctcagggagccgcagcccttgagcccccagcattccggagca
gcgcctcctttgggcaccccaggctgccctgggagtccccaggagccaggcaccatcagg
cagcagggagtcaccctgaacaaccacacgcctcacatgcagtgtgactctccagttgct
agtactgacacttccacaagcaaaaagaagtgtgaccaggaagagggggtgctcagccac
aggagagaaaccaggtccttgagtgtaggggatcaggagtggtgggctagctcccacgca
aagaggaactcagactgggatgagagggtcctggaggaggacagctgctcaaagaagaga
cgggttttatag
DBGET
integrated database retrieval system
