KEGG   Bos taurus (cow): 534492
Entry
534492            CDS       T01008                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
bta  Bos taurus (cow)
Pathway
bta01522  Endocrine resistance
bta04010  MAPK signaling pathway
bta04015  Rap1 signaling pathway
bta04068  FoxO signaling pathway
bta04071  Sphingolipid signaling pathway
bta04114  Oocyte meiosis
bta04148  Efferocytosis
bta04218  Cellular senescence
bta04261  Adrenergic signaling in cardiomyocytes
bta04370  VEGF signaling pathway
bta04380  Osteoclast differentiation
bta04517  IgSF CAM signaling
bta04519  Cadherin signaling
bta04550  Signaling pathways regulating pluripotency of stem cells
bta04611  Platelet activation
bta04613  Neutrophil extracellular trap formation
bta04620  Toll-like receptor signaling pathway
bta04621  NOD-like receptor signaling pathway
bta04622  RIG-I-like receptor signaling pathway
bta04625  C-type lectin receptor signaling pathway
bta04657  IL-17 signaling pathway
bta04658  Th1 and Th2 cell differentiation
bta04659  Th17 cell differentiation
bta04660  T cell receptor signaling pathway
bta04664  Fc epsilon RI signaling pathway
bta04668  TNF signaling pathway
bta04670  Leukocyte transendothelial migration
bta04714  Thermogenesis
bta04722  Neurotrophin signaling pathway
bta04723  Retrograde endocannabinoid signaling
bta04728  Dopaminergic synapse
bta04750  Inflammatory mediator regulation of TRP channels
bta04912  GnRH signaling pathway
bta04914  Progesterone-mediated oocyte maturation
bta04917  Prolactin signaling pathway
bta04926  Relaxin signaling pathway
bta04932  Non-alcoholic fatty liver disease
bta04933  AGE-RAGE signaling pathway in diabetic complications
bta04935  Growth hormone synthesis, secretion and action
bta04936  Alcoholic liver disease
bta05014  Amyotrophic lateral sclerosis
bta05020  Prion disease
bta05022  Pathways of neurodegeneration - multiple diseases
bta05132  Salmonella infection
bta05133  Pertussis
bta05135  Yersinia infection
bta05140  Leishmaniasis
bta05142  Chagas disease
bta05145  Toxoplasmosis
bta05152  Tuberculosis
bta05161  Hepatitis B
bta05163  Human cytomegalovirus infection
bta05167  Kaposi sarcoma-associated herpesvirus infection
bta05169  Epstein-Barr virus infection
bta05170  Human immunodeficiency virus 1 infection
bta05171  Coronavirus disease
bta05205  Proteoglycans in cancer
bta05208  Chemical carcinogenesis - reactive oxygen species
bta05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bta05415  Diabetic cardiomyopathy
bta05417  Lipid and atherosclerosis
bta05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    534492 (MAPK14)
   04015 Rap1 signaling pathway
    534492 (MAPK14)
   04370 VEGF signaling pathway
    534492 (MAPK14)
   04668 TNF signaling pathway
    534492 (MAPK14)
   04068 FoxO signaling pathway
    534492 (MAPK14)
   04071 Sphingolipid signaling pathway
    534492 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    534492 (MAPK14)
   04519 Cadherin signaling
    534492 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    534492 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    534492 (MAPK14)
   04218 Cellular senescence
    534492 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    534492 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    534492 (MAPK14)
   04613 Neutrophil extracellular trap formation
    534492 (MAPK14)
   04620 Toll-like receptor signaling pathway
    534492 (MAPK14)
   04621 NOD-like receptor signaling pathway
    534492 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    534492 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    534492 (MAPK14)
   04660 T cell receptor signaling pathway
    534492 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    534492 (MAPK14)
   04659 Th17 cell differentiation
    534492 (MAPK14)
   04657 IL-17 signaling pathway
    534492 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    534492 (MAPK14)
   04670 Leukocyte transendothelial migration
    534492 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    534492 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    534492 (MAPK14)
   04917 Prolactin signaling pathway
    534492 (MAPK14)
   04926 Relaxin signaling pathway
    534492 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    534492 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    534492 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    534492 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    534492 (MAPK14)
   04722 Neurotrophin signaling pathway
    534492 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    534492 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    534492 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    534492 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    534492 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    534492 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    534492 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    534492 (MAPK14)
   05161 Hepatitis B
    534492 (MAPK14)
   05171 Coronavirus disease
    534492 (MAPK14)
   05163 Human cytomegalovirus infection
    534492 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    534492 (MAPK14)
   05169 Epstein-Barr virus infection
    534492 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    534492 (MAPK14)
   05135 Yersinia infection
    534492 (MAPK14)
   05133 Pertussis
    534492 (MAPK14)
   05152 Tuberculosis
    534492 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    534492 (MAPK14)
   05140 Leishmaniasis
    534492 (MAPK14)
   05142 Chagas disease
    534492 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    534492 (MAPK14)
   05020 Prion disease
    534492 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    534492 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    534492 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    534492 (MAPK14)
   05415 Diabetic cardiomyopathy
    534492 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    534492 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    534492 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    534492 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    534492 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bta01001]
    534492 (MAPK14)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     534492 (MAPK14)
Protein kinases [BR:bta01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   534492 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 534492
NCBI-ProteinID: NP_001095644
BGD-bta: BT11558
Ensembl: ENSBTAG00000020783
VGNC: 31216
UniProt: A6QLR9
LinkDB
Position
23:9970264..10045594
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagaccatctgggaggtg
cccgagcgttaccagaacctgtccccggtgggctccggcgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttacgtgtcgcagtgaagaagctatccagaccatttcag
tccattattcatgccaaaagaacctacagagaactgcggttacttaaacatatgaagcat
gaaaatgtaattggtctgttggatgttttcacacctgcaaggtctctggaggaattcaat
gatgtgtacctggtgacccatctcatgggggcagatctgaacaacatcgtgaaatgtcag
aagcttacagatgaccatgttcagttccttatctaccagattctcagaggtctcaagtat
atacattcagccgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggatttcggactggctcgacatacagatgatgaaatgaca
ggctatgtggccaccaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattaaccagcttcagcagattatgcgtctgacgggg
actccccctgcttatctcattaacaggatgccaagccatgaggcaagaaactacattcag
tctttgacccagatgccgaagatgaactttgcaaatgtatttattggtgccaatcccttg
gctgtcgacctgctggagaagatgcttgtattggactcagataagagaatcacagcagca
caagcccttgcacatgcctacttcgcccagtaccacgatcctgacgacgaaccagtggct
gatccttacgatcagtcttttgaaagcagggacctccttatagacgaatggaaaagcctg
acctatgatgaagtcatcagctttgtgccgccaccccttgaccaagaagagatggagtct
tga

DBGET integrated database retrieval system