Bos taurus (cow): 536132
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Entry
536132 CDS
T01008
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase 1 isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
bta
Bos taurus (cow)
Pathway
bta00220
Arginine biosynthesis
bta00330
Arginine and proline metabolism
bta01100
Metabolic pathways
bta04020
Calcium signaling pathway
bta04081
Hormone signaling
bta04145
Phagosome
bta04371
Apelin signaling pathway
bta04713
Circadian entrainment
bta04730
Long-term depression
bta04926
Relaxin signaling pathway
bta04970
Salivary secretion
bta05010
Alzheimer disease
bta05014
Amyotrophic lateral sclerosis
bta05022
Pathways of neurodegeneration - multiple diseases
bta05410
Hypertrophic cardiomyopathy
bta05412
Arrhythmogenic right ventricular cardiomyopathy
bta05414
Dilated cardiomyopathy
bta05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
536132 (NOS1)
00330 Arginine and proline metabolism
536132 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
536132 (NOS1)
04020 Calcium signaling pathway
536132 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
536132 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
536132 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
536132 (NOS1)
09154 Digestive system
04970 Salivary secretion
536132 (NOS1)
09156 Nervous system
04730 Long-term depression
536132 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
536132 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
536132 (NOS1)
05014 Amyotrophic lateral sclerosis
536132 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
536132 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
536132 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
536132 (NOS1)
05414 Dilated cardiomyopathy
536132 (NOS1)
05416 Viral myocarditis
536132 (NOS1)
Enzymes [BR:
bta01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
536132 (NOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
536132
NCBI-ProteinID:
XP_059732376
BGD-bta:
BT28862
Ensembl:
ENSBTAG00000002023
VGNC:
32172
LinkDB
All DBs
Position
17:57692151..57900831
Genome browser
AA seq
1517 aa
AA seq
DB search
MESHMFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTRPLGPPTAAVDLSHQASAGREQTLVVDGATGPGNGPQHAPDPGQEASSLAHANGLAA
RPPGQDPAKKSTGVALQGSGENNKLLKEIEPVLNLLTSGGKAINGGGPAKTETKDVEIQV
DRDLDGKSHKPLPLGVENDRVFSDLWGKGSMPVVLNNPYSEKEQPPASGKQSPTKNGSPS
KCPRFLKVKNWETDVVLSDTLHLKSTLGTGCTEHICMGSIMLPSQQIRKPEDVRTKEQLF
PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVW
NSQLIRYAGYKQPDGSILGDPANVEFTEICIQQGWKPPRSRFDVLPLLLQANGNDPELFQ
IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDSSRYNILEDVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRNPNSVH
EERKYPEPLRFFPRKGPPLSRGDREVHGLAAVRDSQRRSYKVRFNSVSSYSDSRKSSGDG
PDLRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELT
QGLSSVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
DLVNALIERLEDAPPANQLVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDIT
TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPST
LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
EVVPCFVRGAPSFHLPQNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVF
GCRQSKIDHIYREETLQAKSKGVFRELYTAYSREPDKPKKYVQDILQEQLAEPVYRALKE
QGGHIYVCGDVTMAADVLKAIQRIMTQKGKLSVEDAGVFISRLRDDNRYHEDIFGVTLRT
YEVTNRLRSESIAFIEESKKDTDECESRGLEMLCSTGHLDPDAEGERSDMDGNRFQFCRN
AWMGSPSKAGTTGKEAR
NT seq
4554 nt
NT seq
+upstream
nt +downstream
nt
atggagagccacatgttcagcgttcaacagatccaacccaatgtcatttctgtccgcctc
ttcaagcgcaaagtggggggcctggggttcctggtgaaggagagggtgagcaagccaccc
gtgatcatctctgacctgatccgagggggcgccgcggagcaaagcggcctcatccaggct
ggggacatcattctcgccgtcaatggccagcccttggtggacctgagctacgacagcgcc
ctggaggtgctcagggggattgcctctgagacccacgtggtgctcatcctcaggggcccc
gagggcttcaccacgcacctggagaccaccttcaccggggacgggacccccaagaccatc
cgggtgacccggcccctgggtccccccacagcagccgttgacctatcccaccaagcgtca
gccggcagagagcagacgctggtggtggacggggccacagggcccggcaatgggccccag
catgcgccagacccggggcaggaagccagctccctcgcccatgccaacggcctggctgcc
aggcccccaggccaggacccagccaagaaaagcactggggtcgccctccagggcagcgga
gagaacaataaactgctcaaagagatagagcctgtcctgaaccttctcaccagtgggggc
aaagcgatcaatggagggggacctgccaagacagagaccaaggacgtggaaatccaggtg
gacagagacctggacggcaaatcacacaaacctctgcccctcggcgtggagaacgaccga
gtcttcagtgacctgtgggggaagggcagcatgcccgtcgtcctcaacaacccgtactca
gagaaggagcagccccctgcctcgggaaaacagtctcccacaaagaatggcagcccctcc
aagtgccctcgcttcctcaaggtcaagaactgggagaccgacgtggttctctctgacacc
ctccacctcaagagcacgttgggaacgggatgcactgagcacatctgtatggggtccatc
atgctcccttctcagcaaatacgaaagcctgaagacgtccgcacaaaagaacagctcttt
ccccttgccaaagagttcattgatcagtactactcatcaattaaaaggtttggctccaaa
gcccacatggagaggctggaagaggtgaacaaagaaatcgaaaccaccagcacctaccag
ctcaaggacacagagctcatctacggggccaagcacgcctggcggaatgcctcccgctgt
gttggcaggatccagtggtccaagctgcaggtgtttgatgcccgagactgtaccactgct
catgggatgttcaactacatctgtaaccacatcaagtatgccaccaacaaagggaacctc
agatctgcgatcaccatatttccccagaggaccgacggcaagcacgacttccgcgtttgg
aactcccaactcatccgctacgctggctacaagcagcccgacggctccatcctgggggac
ccagccaacgtggagttcacggagatctgcatacagcagggctggaaacccccacgaagc
cgcttcgatgtcctgccactcctgctccaggcaaacggcaatgacccagagctcttccag
atccctccagagttggtgctggaagtccccatcaggcaccccaagtttgagtggttcaag
gacctgggactgaagtggtacggcctccctgctgtgtccaacatgctcctggagatcggc
ggcctggagttcagcgcgtgtcccttcagcggctggtacatgggcacagagattggcgtc
cgcgactactgcgacagctcccgatacaacatcctggaggatgtggccaagaagatgaac
ttggacatgaggaagacatcctctctgtggaaggaccaggcactggtggagatcaatatt
gcggttctgtacagcttccagagtgacaaggtgaccatcgtcgaccaccactccgccacc
gagtccttcattaagcacatggagaatgaataccgctgccgggggggctgccccgctgac
tgggtgtggatcgtgccccccatgtctggcagtatcacccctgtcttccaccaggagatg
ctcaactaccggctcacaccctccttcgaataccagcctgacccttggaacacccatgtc
tggaaaggcaccaacgggacccccacaaaacggcgagccatcggcttcaagaagctggca
gaagccgtcaagttctcagccaaactgatggggcaggctatggccaagagggtcaaggct
accatcctttatgccacagagacgggcaagtcgcaggcttatgccaaaaccttgtgtgag
atcttcaaacatgcttttgatgccaaggtgatgtccatggaagaatatgacattgtacac
ctggaacatgaaactctggtcctggtggttaccagcacctttggcaatggagacccccct
gagaatggggagaaatttggctgtgctctgatggaaatgaggaaccctaactctgtgcac
gaggaaaggaagtacccggaacccttgcgtttctttccccgtaaagggcctcccctctcc
cgtggtgacagagaagtccacggtctggctgcagttcgtgacagccagcgcaggagctac
aaggtgcgtttcaacagcgtttcctcgtactccgactcccgcaaatcatcaggtgatggg
ccagacctcagagacaactttgagagtactggacccctggccaacgtgaggttctctgtg
ttcggtcttggctcacgggcataccctcacttctgcgcctttggacatgccgtggacact
ctcctggaagagcttggaggagagaggatcttgaagatgagggagggggacgagctttgt
gggcaggaagaggctttcaggacctgggctaagaaggtcttcaaggcagcctgtgatgtg
ttctgcgtgggtgatgacgtcaacattgagaaggcgaacaactccctcatcagcaatgac
cgcagctggaagaggaacaagttccgtctcacctacgtggcggaagctccggaactcaca
caaggtctatccagtgtccacaaaaagcgggtctcagccgctcgactcctcagccgccag
aaccttcagagtccaaaatccagtcgatcgaccatcttcgtgcgtctccacaccaatggg
agtcaggagctgcagtaccagcccggggaccacctgggcgtcttccccggcaaccacgag
gacctggtgaatgccctgatcgagcggctggaggatgccccccctgccaaccagttggtg
aaggtggagctgctggaggagcggaacacggctttgggggttatcagtaactggaccgat
gagcatcgcctgccgccctgcaccatcttccaggccttcaagtactacctggacatcacg
acgcctccaacgccactgcagctgcagcagtttgcctccctggccaccagtgagaaagag
aagcagcgtctgctggtcctcagcaagggtctgcaggagtacgaggaatggaaatggggc
aagaaccccaccatcgtggaagtgctggaggagttcccgtccatccagatgccctccacc
ctgctcctgacccagctgtccctgctgcagcctcgctactattccatcagctcctccccg
gacatgtaccccgacgaggtgcacctcaccgtggccatcgtctcctaccgcacccgagat
ggagaaggaccaattcaccacggcgtgtgctcctcctggctcaaccggatccaggctgac
gaagtggtgccctgtttcgtgagaggagcgcccagcttccacctgccccaaaatccccaa
gtgccctgtatcctggttggcccaggcactggcatcgcccccttccggagcttctggcag
cagcggcaatttgatatccaacacaaaggaatgagcccctgccccatggtcctggtcttc
gggtgccggcagtccaagatagaccacatctacagggaggagaccctgcaggccaagagc
aagggggtcttcagagagctgtacacagcctactcccgggagccagacaaaccaaagaag
tacgtgcaagacatcctacaagagcagctggcggaacccgtgtatcgagccctgaaggag
caagggggccacatctatgtgtgcggggatgtcaccatggcggccgatgtcctcaaagcc
atccagcgcatcatgacgcagaagggcaagctctctgtggaggacgctggtgtgttcatc
agcaggctgagggatgacaaccgctaccatgaggatattttcggggtcaccctgcgcaca
tatgaagtgaccaaccgccttagatctgaatccattgccttcattgaggagagcaagaaa
gacaccgatgaatgtgaaagcagaggcttggagatgttatgctctactgggcatttggac
ccagatgctgagggagagagaagtgacatggatggcaacaggttccagttttgcaggaat
gcatggatgggtagcccttccaaggcaggaaccactgggaaagaagcaaggtaa
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integrated database retrieval system
