Bos taurus (cow): 537682
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Entry
537682 CDS
T01008
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
bta
Bos taurus (cow)
Pathway
bta01521
EGFR tyrosine kinase inhibitor resistance
bta01522
Endocrine resistance
bta04010
MAPK signaling pathway
bta04012
ErbB signaling pathway
bta04014
Ras signaling pathway
bta04062
Chemokine signaling pathway
bta04068
FoxO signaling pathway
bta04072
Phospholipase D signaling pathway
bta04150
mTOR signaling pathway
bta04151
PI3K-Akt signaling pathway
bta04510
Focal adhesion
bta04540
Gap junction
bta04630
JAK-STAT signaling pathway
bta04650
Natural killer cell mediated cytotoxicity
bta04660
T cell receptor signaling pathway
bta04662
B cell receptor signaling pathway
bta04664
Fc epsilon RI signaling pathway
bta04714
Thermogenesis
bta04722
Neurotrophin signaling pathway
bta04810
Regulation of actin cytoskeleton
bta04910
Insulin signaling pathway
bta04912
GnRH signaling pathway
bta04915
Estrogen signaling pathway
bta04917
Prolactin signaling pathway
bta04926
Relaxin signaling pathway
bta04935
Growth hormone synthesis, secretion and action
bta05034
Alcoholism
bta05160
Hepatitis C
bta05161
Hepatitis B
bta05163
Human cytomegalovirus infection
bta05165
Human papillomavirus infection
bta05200
Pathways in cancer
bta05205
Proteoglycans in cancer
bta05206
MicroRNAs in cancer
bta05207
Chemical carcinogenesis - receptor activation
bta05208
Chemical carcinogenesis - reactive oxygen species
bta05210
Colorectal cancer
bta05211
Renal cell carcinoma
bta05213
Endometrial cancer
bta05214
Glioma
bta05215
Prostate cancer
bta05220
Chronic myeloid leukemia
bta05221
Acute myeloid leukemia
bta05223
Non-small cell lung cancer
bta05224
Breast cancer
bta05225
Hepatocellular carcinoma
bta05226
Gastric cancer
bta05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
537682 (SOS1)
04012 ErbB signaling pathway
537682 (SOS1)
04014 Ras signaling pathway
537682 (SOS1)
04630 JAK-STAT signaling pathway
537682 (SOS1)
04068 FoxO signaling pathway
537682 (SOS1)
04072 Phospholipase D signaling pathway
537682 (SOS1)
04151 PI3K-Akt signaling pathway
537682 (SOS1)
04150 mTOR signaling pathway
537682 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
537682 (SOS1)
04540 Gap junction
537682 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
537682 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
537682 (SOS1)
04660 T cell receptor signaling pathway
537682 (SOS1)
04662 B cell receptor signaling pathway
537682 (SOS1)
04664 Fc epsilon RI signaling pathway
537682 (SOS1)
04062 Chemokine signaling pathway
537682 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
537682 (SOS1)
04912 GnRH signaling pathway
537682 (SOS1)
04915 Estrogen signaling pathway
537682 (SOS1)
04917 Prolactin signaling pathway
537682 (SOS1)
04926 Relaxin signaling pathway
537682 (SOS1)
04935 Growth hormone synthesis, secretion and action
537682 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
537682 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
537682 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
537682 (SOS1)
05206 MicroRNAs in cancer
537682 (SOS1)
05205 Proteoglycans in cancer
537682 (SOS1)
05207 Chemical carcinogenesis - receptor activation
537682 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
537682 (SOS1)
05231 Choline metabolism in cancer
537682 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
537682 (SOS1)
05225 Hepatocellular carcinoma
537682 (SOS1)
05226 Gastric cancer
537682 (SOS1)
05214 Glioma
537682 (SOS1)
05221 Acute myeloid leukemia
537682 (SOS1)
05220 Chronic myeloid leukemia
537682 (SOS1)
05211 Renal cell carcinoma
537682 (SOS1)
05215 Prostate cancer
537682 (SOS1)
05213 Endometrial cancer
537682 (SOS1)
05224 Breast cancer
537682 (SOS1)
05223 Non-small cell lung cancer
537682 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
537682 (SOS1)
05160 Hepatitis C
537682 (SOS1)
05163 Human cytomegalovirus infection
537682 (SOS1)
05165 Human papillomavirus infection
537682 (SOS1)
09165 Substance dependence
05034 Alcoholism
537682 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
537682 (SOS1)
01522 Endocrine resistance
537682 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
537682
NCBI-ProteinID:
XP_002691287
BGD-bta:
BT17095
Ensembl:
ENSBTAG00000011643
VGNC:
35134
UniProt:
A0AAA9TIR9
LinkDB
All DBs
Position
11:complement(21303811..21434957)
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYNYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TKSTDEVPVPPPVPPRRRPESAPAESSPSKMMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcatccaactcttgagtct
agtgatgatgctcttcagtatgttgaagaattaattttgcagctattaaatatgctctgc
caagctcaaccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaatccatcctttgttaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtgcgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattaatggatatgtttcatcaagatgtg
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcagact
tactatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaacttaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtggatatacatgaacttagtgtaaaattactg
ggccatatagaagatactgtggaaatgacagatgaaggcagtccccatccattagtagga
agctgctttgaagacttagcggaggaactggcatttgatccatatgaatcatatgctcga
gatattctacgacctggttttcacgatcgtttccttagtcagttatcaaagcctggagca
gcgctctatttgcagtcaataggcgaaggtttcaaagaagctgttcaatatgttttaccc
agactacttctagcccctgtttaccactgtctgcattacttcgaacttctgaagcagtta
gaagaaaagagtgaggatcaagaagacaaagaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactt
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagacta
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaagaacaattggatggcagca
ttgatatctttacagtaccggagtaccctggaaagaatgcttgatgtgaccatgctgcag
gaagaaaaggaggagcagatgaggctccctagtgctgacgtttatagatttgcagagcct
gactctgaagaaaatatcatatttgaagaaaacgtgcagcccaaagctggaattccaatt
atcaaggcaggaaccgttattaaacttatagagaggctcacataccacatgtatgcagat
cccaattttgttcggacatttcttacaacatatagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atcgctatagagaatggggatcaacccttgagtgcagaactaaagagatttagaaaagaa
tatatacagcctgtgcagctgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctatgattttgaaagagatgcagatcttttgcagcgaatggaggaatttattggaacc
gtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgccagagacaatggaccaggtcataatattacatttcagagttcacctcctacg
gttgagtggcatataagcagacctgggcacatcgagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcacaccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctacaa
gtgttccaagagctcaacaacttcaatggtgttcttgaggttgtcagtgctatgaactca
tcccctgtttacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaactaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctcactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaacggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggcgagatccagcagtaccaaaatcagccttactgt
ttacgagtagagtcagatatcaaaaggttttttgaaaacttgaatccaatgggaaatagc
atggaaaaagaatttacggattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctcttccaagatttccaaaaaaatacaactatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtactatgagacatcccacacctctgcagcaagagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaaggacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtatttgattctgatcattcaagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagagcactgatgaagtgcctgtcccccctcctgttcctccacgaagacggccagag
tctgccccagcggaatcttcaccatctaagatgatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacggtattcaatatcagac
cggacctctatatcagaccctcctgaaagccctcccttattacctccacgagaacctgtg
aggacacctgatgttttctcaagttcaccactacatctccaacctccccctctgggcaaa
aaaagtgaccatagtaatgccttcttcccaaacagcccctccccctttacaccacctcct
cctcaaacaccttctcctcatggaacaagaaggcatctgccgtcaccaccactgacacaa
gaagtggacctccattccattgctgggccgcctgttcctccacgacaaagcacttctcag
catatccctaaactccctccaaaaacttacaaaagggagcacacccacccgtccatgcac
agagacgggccaccactgttggagaatgcccattcttcctga
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integrated database retrieval system
