Bos taurus (cow): 539579 Help Entry 539579            CDS       T01008                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism bta  Bos taurus (cow) Pathway bta00010   Glycolysis / Gluconeogenesis bta00620   Pyruvate metabolism bta01100   Metabolic pathways bta01200   Carbon metabolism bta01230   Biosynthesis of amino acids bta04910   Insulin signaling pathway bta04930   Type II diabetes mellitus bta04932   Non-alcoholic fatty liver disease bta04950   Maturity onset diabetes of the young Module bta_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate bta_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:bta00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     539579 (PKLR)    00620 Pyruvate metabolism     539579 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     539579 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     539579 (PKLR)    04950 Maturity onset diabetes of the young     539579 (PKLR)    04932 Non-alcoholic fatty liver disease     539579 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:bta04147]     539579 (PKLR) Enzymes [BR:bta01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      539579 (PKLR) Exosome [BR:bta04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    539579 (PKLR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Neuregulin Motif Other DBs NCBI-GeneID:  539579 NCBI-ProteinID:  NP_001069644 BGD-bta:  BT12238 Ensembl:  ENSBTAG00000017056 VGNC:  32943 UniProt:  Q1JPG7 LinkDB All DBs Position 3:15344803..15354042 Genome browser AA seq 526 aa AA seqDB search MEQIPGDRQRQQLPATMADTFLEHLCLLDIDSEPVVARSTSIIATIGPASRSVERLKEMI EAGMNIARLNFSHGSHEYHAESIANIREAVESFANSPLSYRPVAIALDTKGPEIRTGILQ GDPASEVEIVKGSRVLVTVDPEFQTRGDANTVWVDYPNIVRVMPVGGRIYIDDGLISLVV KKIGPEGLETEVENGGVLGSRKGVNLPGTQVDLPGLSEQDVQDLRFGVEHGVDIVFVSFV RKASDVAAVRDALGPEGQGIKIVSKIENHEGVKKFNEILEVSDGIMVARGDLGIEIPAEK VFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGET AKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCA GAIIVLTTTGRSAQLLSRYRPRATVIAVTRSAQAARQAHLCRGVFPVLYREPPEDIWADD VDRRVQFGIDNGKLCGFLSSGDLVIVVTGWQPGSGHTNIMRVLSVT NT seq 1581 nt NT seq  +upstreamnt  +downstreamnt atggagcagatccccggagacaggcagcggcagcagctgccagccactatggcagacacc ttcctggaacatctgtgcctgctggacatcgactctgagcctgtggtcgctcgcagtacc agtatcatcgccaccatcgggccggcatctcgctccgtggagcgtctcaaggagatgatc gaggccgggatgaacatcgcgagactcaacttctcccacggctcccacgagtaccacgct gagtccatcgctaacatccgggaggcggtggagagctttgcaaattctccgctcagctac cgacccgtggccatcgccctggacaccaagggaccagagatacgcactgggatcctgcaa ggggacccggcgtcagaagtggagatagtgaagggctcccgggtgctggtgaccgtggac ccagagttccagacccgcggggacgcgaacaccgtgtgggtggactaccccaatatcgtc cgagtcatgccggtggggggccgcatctacattgacgacgggctcatctccctagtggtc aagaaaatcggtccggaagggctagagaccgaagtggagaacggcggtgtcctgggcagt cggaagggcgtgaacttgccaggcacccaggtggacctgcccgggctgtccgagcaagat gtccaggacctgcgcttcggggtggagcatggcgtggacatcgtctttgtctctttcgtg cggaaagccagcgacgtggctgccgtccgggatgctctggggccggaaggacagggcatc aagatcgttagcaaaatcgagaaccacgagggcgtaaagaagttcaatgaaatcctggag gtgagcgacggtattatggtggcacggggtgacctgggcattgagatcccggctgagaag gttttcctggctcagaagatgatgatcggccgttgcaacttggcgggaaagcccgttgtc tgtgctacacagatgctggagagcatgatcactaagccccggccaactcgggcagagacg agtgacgtggccaatgctgttctggatggggcagactgcatcatgctgtcaggggagact gccaaaggcaactttcctgtggaggctgtaaagatgcagcatgcgattgcccgggaggca gaggctgccgtgtaccaccggcagctctttgaggagctacgccgggcagcaccactgagc cgggatcccacggaggtcaccgctattggtgctgtggaggctgccttcaagtgctgtgct ggtgccatcattgtgctgaccacaactggccgctcagcccagcttctgtcccggtaccga cctcgggcaacagtcattgccgtcacccgctctgctcaggctgcccgccaggcccacctg tgccgaggagtcttccctgtgctctaccgtgaacctccagaggacatctgggccgatgat gtggaccgtcgggtccaatttggcatcgacaatggaaagctctgtggcttcctcagttct ggggacctggtgattgtggtgacaggctggcaaccaggctccggccataccaacatcatg cgggtgctgagcgtaacctga

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