Bos taurus (cow): 541140 Help Entry 541140            CDS       T01008                                  Symbol KRAS Name (RefSeq) GTPase KRas   KO K07827   GTPase KRas Organism bta  Bos taurus (cow) Pathway bta01521   EGFR tyrosine kinase inhibitor resistance bta01522   Endocrine resistance bta04010   MAPK signaling pathway bta04012   ErbB signaling pathway bta04014   Ras signaling pathway bta04015   Rap1 signaling pathway bta04062   Chemokine signaling pathway bta04068   FoxO signaling pathway bta04071   Sphingolipid signaling pathway bta04072   Phospholipase D signaling pathway bta04137   Mitophagy - animal bta04140   Autophagy - animal bta04150   mTOR signaling pathway bta04151   PI3K-Akt signaling pathway bta04210   Apoptosis bta04211   Longevity regulating pathway bta04213   Longevity regulating pathway - multiple species bta04218   Cellular senescence bta04360   Axon guidance bta04370   VEGF signaling pathway bta04371   Apelin signaling pathway bta04519   Cadherin signaling bta04540   Gap junction bta04550   Signaling pathways regulating pluripotency of stem cells bta04625   C-type lectin receptor signaling pathway bta04650   Natural killer cell mediated cytotoxicity bta04660   T cell receptor signaling pathway bta04662   B cell receptor signaling pathway bta04664   Fc epsilon RI signaling pathway bta04714   Thermogenesis bta04720   Long-term potentiation bta04722   Neurotrophin signaling pathway bta04725   Cholinergic synapse bta04726   Serotonergic synapse bta04730   Long-term depression bta04810   Regulation of actin cytoskeleton bta04910   Insulin signaling pathway bta04912   GnRH signaling pathway bta04914   Progesterone-mediated oocyte maturation bta04915   Estrogen signaling pathway bta04916   Melanogenesis bta04917   Prolactin signaling pathway bta04919   Thyroid hormone signaling pathway bta04921   Oxytocin signaling pathway bta04926   Relaxin signaling pathway bta04929   GnRH secretion bta04933   AGE-RAGE signaling pathway in diabetic complications bta04935   Growth hormone synthesis, secretion and action bta04960   Aldosterone-regulated sodium reabsorption bta05010   Alzheimer disease bta05022   Pathways of neurodegeneration - multiple diseases bta05034   Alcoholism bta05160   Hepatitis C bta05161   Hepatitis B bta05163   Human cytomegalovirus infection bta05165   Human papillomavirus infection bta05166   Human T-cell leukemia virus 1 infection bta05167   Kaposi sarcoma-associated herpesvirus infection bta05170   Human immunodeficiency virus 1 infection bta05200   Pathways in cancer bta05203   Viral carcinogenesis bta05205   Proteoglycans in cancer bta05206   MicroRNAs in cancer bta05207   Chemical carcinogenesis - receptor activation bta05208   Chemical carcinogenesis - reactive oxygen species bta05210   Colorectal cancer bta05211   Renal cell carcinoma bta05212   Pancreatic cancer bta05213   Endometrial cancer bta05214   Glioma bta05215   Prostate cancer bta05216   Thyroid cancer bta05218   Melanoma bta05219   Bladder cancer bta05220   Chronic myeloid leukemia bta05221   Acute myeloid leukemia bta05223   Non-small cell lung cancer bta05224   Breast cancer bta05225   Hepatocellular carcinoma bta05226   Gastric cancer bta05230   Central carbon metabolism in cancer bta05231   Choline metabolism in cancer bta05235   PD-L1 expression and PD-1 checkpoint pathway in cancer bta05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     541140 (KRAS)    04012 ErbB signaling pathway     541140 (KRAS)    04014 Ras signaling pathway     541140 (KRAS)    04015 Rap1 signaling pathway     541140 (KRAS)    04370 VEGF signaling pathway     541140 (KRAS)    04371 Apelin signaling pathway     541140 (KRAS)    04068 FoxO signaling pathway     541140 (KRAS)    04072 Phospholipase D signaling pathway     541140 (KRAS)    04071 Sphingolipid signaling pathway     541140 (KRAS)    04151 PI3K-Akt signaling pathway     541140 (KRAS)    04150 mTOR signaling pathway     541140 (KRAS)   09133 Signaling molecules and interaction    04519 Cadherin signaling     541140 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     541140 (KRAS)    04137 Mitophagy - animal     541140 (KRAS)   09143 Cell growth and death    04210 Apoptosis     541140 (KRAS)    04218 Cellular senescence     541140 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     541140 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     541140 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     541140 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     541140 (KRAS)    04650 Natural killer cell mediated cytotoxicity     541140 (KRAS)    04660 T cell receptor signaling pathway     541140 (KRAS)    04662 B cell receptor signaling pathway     541140 (KRAS)    04664 Fc epsilon RI signaling pathway     541140 (KRAS)    04062 Chemokine signaling pathway     541140 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     541140 (KRAS)    04929 GnRH secretion     541140 (KRAS)    04912 GnRH signaling pathway     541140 (KRAS)    04915 Estrogen signaling pathway     541140 (KRAS)    04914 Progesterone-mediated oocyte maturation     541140 (KRAS)    04917 Prolactin signaling pathway     541140 (KRAS)    04921 Oxytocin signaling pathway     541140 (KRAS)    04926 Relaxin signaling pathway     541140 (KRAS)    04935 Growth hormone synthesis, secretion and action     541140 (KRAS)    04919 Thyroid hormone signaling pathway     541140 (KRAS)    04916 Melanogenesis     541140 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     541140 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     541140 (KRAS)    04726 Serotonergic synapse     541140 (KRAS)    04720 Long-term potentiation     541140 (KRAS)    04730 Long-term depression     541140 (KRAS)    04722 Neurotrophin signaling pathway     541140 (KRAS)   09158 Development and regeneration    04360 Axon guidance     541140 (KRAS)   09149 Aging    04211 Longevity regulating pathway     541140 (KRAS)    04213 Longevity regulating pathway - multiple species     541140 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     541140 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     541140 (KRAS)    05206 MicroRNAs in cancer     541140 (KRAS)    05205 Proteoglycans in cancer     541140 (KRAS)    05207 Chemical carcinogenesis - receptor activation     541140 (KRAS)    05208 Chemical carcinogenesis - reactive oxygen species     541140 (KRAS)    05203 Viral carcinogenesis     541140 (KRAS)    05230 Central carbon metabolism in cancer     541140 (KRAS)    05231 Choline metabolism in cancer     541140 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     541140 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     541140 (KRAS)    05212 Pancreatic cancer     541140 (KRAS)    05225 Hepatocellular carcinoma     541140 (KRAS)    05226 Gastric cancer     541140 (KRAS)    05214 Glioma     541140 (KRAS)    05216 Thyroid cancer     541140 (KRAS)    05221 Acute myeloid leukemia     541140 (KRAS)    05220 Chronic myeloid leukemia     541140 (KRAS)    05218 Melanoma     541140 (KRAS)    05211 Renal cell carcinoma     541140 (KRAS)    05219 Bladder cancer     541140 (KRAS)    05215 Prostate cancer     541140 (KRAS)    05213 Endometrial cancer     541140 (KRAS)    05224 Breast cancer     541140 (KRAS)    05223 Non-small cell lung cancer     541140 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     541140 (KRAS)    05170 Human immunodeficiency virus 1 infection     541140 (KRAS)    05161 Hepatitis B     541140 (KRAS)    05160 Hepatitis C     541140 (KRAS)    05163 Human cytomegalovirus infection     541140 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     541140 (KRAS)    05165 Human papillomavirus infection     541140 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     541140 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     541140 (KRAS)   09165 Substance dependence    05034 Alcoholism     541140 (KRAS)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     541140 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     541140 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     541140 (KRAS)    01522 Endocrine resistance     541140 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:bta04131]     541140 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:bta04031]     541140 (KRAS) Membrane trafficking [BR:bta04131]  Endocytosis   Macropinocytosis    Ras GTPases     541140 (KRAS) GTP-binding proteins [BR:bta04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     541140 (KRAS) SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N MeaB ATP_bind_1 G1_gp67_C Septin DUF6974 TPR_Trm732 NPR1_interact Motif Other DBs NCBI-GeneID:  541140 NCBI-ProteinID:  NP_001103471 BGD-bta:  BT12323 Ensembl:  ENSBTAG00000009778 VGNC:  30710 UniProt:  E1BMX0 LinkDB All DBs Position 5 Genome browser AA seq 188 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK SKTKCIIM NT seq 567 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggattcctac aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaata aaaagagttaaagactctgaagatgtacctatggttctagtaggaaataaatgtgatttg ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct tttattgaaacatcagcaaagacaagacagggtgttgacgatgccttctatacattagtt cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag tcaaagacaaagtgtataattatgtaa

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