KEGG   Bos taurus (cow): 541275
Entry
541275            CDS       T01008                                 
Symbol
ATP7A
Name
(RefSeq) copper-transporting ATPase 1
  KO
K17686  P-type Cu+ transporter [EC:7.2.2.8]
Organism
bta  Bos taurus (cow)
Pathway
bta01524  Platinum drug resistance
bta04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:bta00001]
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    541275 (ATP7A)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    541275 (ATP7A)
Enzymes [BR:bta01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.8  P-type Cu+ transporter
     541275 (ATP7A)
SSDB
Motif
Pfam: HMA E1-E2_ATPase Hydrolase DUF6286 Hydrolase_3 HMA_PCA1 Hydrolase_6 HAD_2
Other DBs
NCBI-GeneID: 541275
NCBI-ProteinID: NP_001179781
BGD-bta: BT17418
Ensembl: ENSBTAG00000010018
VGNC: 26327
UniProt: G3X6T7
LinkDB
Position
X:complement(74360086..74490931)
AA seq 1500 aa
MDLSVSVNSVTISVEGMTCSSCVWTIEQQIGKLNGVHHIKVSLEEKNATVIYDPKLQTPK
TLQEAIDDMGFDAILHNPKPLPVLTETVFLTVTASLVPPWDHIQSTLLKTKGVTDIKISP
QQRTAVVTIIPSIVNANQIVELVPDLSLDTGTLEKKSGTCEDYSMAQPGEVMLKMKVEGM
TCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATVVYQPHLITAEEIKKQIEVVGFTAFIKK
QPKYLKLGAIDIERLKNTPVKSSEGSQQKSPSYTSNSTVIFTIDGMHCKSCVSNIESALS
TLQHISSVVVSLENKSAIVKYNASLVTPETLRKAIEAISQGQYRVSSASEIESTSNSPSS
SSLQKSPLNIVSQPLTQETVINIDGMTCNSCVQSIEGVISKKAGVKSIQVSLANGKGTVE
YDPLLTSPETLREAIENMGFDASLSDTNEPLVVIAQPSSEMPLLTSTNEFHTKMMTPIHD
KEEPKTSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPALIQPP
VIAELIRELGFGSTVIENADEGDGVLELVVRGMTCASCVHKIESTLTKHRGIFYCSVALA
TNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRAFLVSLFF
CIPVMGLMIYMMVMDHHLASLQHNQNMSQEEMINIHSSMFLERQILPGLSIMNLLSFLLC
VPVQFFGGWHFYIQAYKALKHKTANMDVLIVLATTIAFAYSLVILLVAMYERAKVNPVTF
FDTPPMLFVFIALGRWLEHVAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVE
LVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKSGSTVIAGSINQNGSL
LIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVIVSIATLLVWIIIG
FLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGA
QNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVESNRISRNKILAIVGTA
ESNSEHPLGAAITKYCKQELDTETLGTCIDFQVVPGCGINCKVTNIEALLHKNNWKIEEN
NIKNASLVQIDESNEQSSTSSSMIIDAQFSNALNAQQYKVLIGNREWMIRNGLAINNSVN
DSMTEHERRGRTAVLVAVDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKT
ARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGT
GTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLIGIPIAAGVFMPI
GLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYENYELHARNQMGQKSPSEISVHVGI
DDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLNSVGTSEPDKHSLLVGDCREDDDSAL
NT seq 4503 nt   +upstreamnt  +downstreamnt
atggatctgagtgtgagtgtgaattctgtcaccatctctgttgagggaatgacatgtagt
tcctgtgtttggaccattgaacagcagattggaaaactgaatggtgtacatcatattaaa
gtttcactggaagaaaaaaatgcaactgttatttatgacccaaaactacaaactccaaag
accctgcaggaagctattgatgacatgggctttgatgctattctccacaatcctaagcct
ctccctgttttaactgaaactgtgtttctgactgttactgcttcactggttccgccatgg
gaccatatccaaagcacattgctcaagaccaagggtgtgacagatattaaaatttcccct
cagcagagaactgcagtggtgacaataatcccttctatagtgaatgccaatcagatagta
gagctggttcctgatctcagtttagatactggaactctggaaaaaaagtcaggaacttgc
gaagattatagtatggctcaaccaggtgaagtcatgctgaagatgaaggtggaagggatg
acctgccattcatgtactagcaccattgaaggaaaaattgggaaactgcaaggtgttcag
cgaattaaagtttccttggacaatcaagaagctactgttgtttatcaaccccatcttatc
acagcagaggaaataaaaaagcagattgaagttgtgggctttacagcattcatcaaaaaa
cagcccaagtacctcaaattgggagctattgacatagaacgtctaaagaacacaccagtc
aaatcctcagaaggatcacagcaaaagagtccatcatacaccagtaattcaacagtcatt
ttcaccatagatggcatgcattgtaaatcatgtgtgtcaaatattgaaagtgctttatct
acactccaacatataagcagtgtagtagtttctttagagaataaatctgccatagtaaag
tacaatgcaagtttagtcactccagaaacactgagaaaagcaatagaggccatatcacaa
gggcaatatagagttagtagtgcaagtgaaattgagagtacctcaaactctccctccagc
tcatctcttcaaaagagtcctttgaacatagttagccagcctctaactcaagaaactgtg
ataaacattgatggcatgacttgtaattcgtgtgtgcagtctattgaaggtgtcatatca
aaaaaggcaggtgtaaaatccatacaagtatcacttgcaaatggcaaagggactgttgag
tatgatcctttactaacctctccagaaaccttgagagaagcaatagaaaacatgggattt
gatgcttccttgtcagatacaaatgagccattggtagtaatagctcagccctcatcagaa
atgccacttttgacctcaactaatgaatttcacaccaaaatgatgacaccaattcatgac
aaggaggagccaaagacttcatccaagtgttatatacaggtcactggtatgacttgtgct
tcctgtgtagcaaacattgaacggaatttaagacgagaagaaggaatatattccatactt
gtggctctgatggctggcaaggcagaagtaaggtataaccctgctctcatacaaccccca
gtgatagccgagttaatccgagagcttggatttggatccactgtgatagaaaatgctgat
gaaggagatggtgttttggaacttgttgtgagaggaatgacatgtgcctcctgtgtccat
aaaatagagtctaccctcacaaaacacagagggatcttctactgctctgtggccctggca
accaacaaagcacatattaaatatgatccagaaattattggtcccagagatattattcat
acaattgaaagcttgggttttgaagcttctttggtcaagaaggaccggtcagcaagccac
ctagaccataaacgggaaataagacagtggcgacgggcctttcttgtgagcctatttttc
tgtatacctgtaatgggactgatgatatatatgatggttatggaccaccatcttgcaagt
cttcaacataatcagaacatgagccaagaagaaatgatcaacattcattcttctatgttc
ctggagcgccagatcctgccaggattgtccattatgaatttgctatcttttttattgtgt
gttcctgtacagttttttggaggctggcacttctatattcaggcctacaaagcactgaag
cataaaactgcaaatatggatgtattgattgtgctggcaacaaccattgcatttgcttac
tctttggttattcttctggttgcaatgtatgagagagccaaagtgaaccctgttactttc
tttgacacacctcctatgctatttgtgtttattgcactaggccggtggctggaacatgta
gcaaagggcaaaacatcagaggctcttgccaaactaatttcactacaagctacagaagca
actattgtaactcttgactctgataatatcctcttgagtgaagagcaagtggatgtggaa
cttgtacaacgtggagacattattaaagtggttccaggaggcaaatttccagtggatggg
cgtgttattgaaggacattctatggtagatgagtccctcatcacaggagaggcaatgcct
gtggccaagaaatctggaagcacagtgattgctggttccattaaccagaatgggtcactc
cttatccgtgcaacccatgttggagcagacacaaccctttctcaaattgtcaaacttgta
gaggaggcacaaacatcaaaggctcctatccagcagtttgcagacaaactcagtggctac
tttgttccttttattgttattgtttccattgctacccttttggtttggattataattgga
tttctgaattttgaaatcgtggaaacctactttcccggctacaacagaagtatctcccga
acagaaacaataatacgctttgctttccaagcctctatcacagttctatgcattgcatgc
ccctgttccctgggactggccactccaactgctgtgatggtgggtacaggagtaggtgct
caaaatggcatactaatcaaaggtggtgagccattggagatggctcataaggtaaaggta
gtggtatttgataaaactggaaccattacccatggaaccccagtagtgaatcaagtaaag
gttctagtggaaagtaatagaatatcacgcaataagatcctggctattgtgggaactgct
gaaagtaacagtgaacaccctctgggagcagccataacgaaatactgcaagcaggagctg
gatactgaaaccttgggtacctgcatagatttccaggttgtgccaggctgtggcattaac
tgtaaagtcaccaatatcgaagccttgctacacaagaataactggaagatagaggaaaat
aatattaaaaatgcatccctggttcaaatagatgagagtaatgaacagtcatcaacttcg
tcttccatgattattgatgctcagttctcaaatgctcttaatgctcagcagtacaaagtt
ctcattggcaaccgggagtggatgattagaaatggtcttgccattaataacagtgtaaat
gattccatgactgaacatgagagaagaggtcggactgctgtactggtagcagttgatgat
gagctgtgcggtttgatagctattgctgatacagtgaagcctgaagcagaactggctgtc
catattctgaaatctatgggcttagaagtagttctgatgactggagacaacagtaaaaca
gctagatctattgcttctcaggttggcattactaaagtgtttgctgaagttctaccttcc
cacaaggttgctaaggtgaagcaacttcaagaggaggggaaacgggtagcaatggtagga
gatggaatcaatgactccccagctctggcgatggctaatgttggaattgctattggcaca
ggcacagatgtagccattgaagcagctgatgtggttttaataaggaatgatcttctggat
gtagtggcaagtattgatttatcaaggaagacagtcaagaggattcggataaattttgtc
tttgctctaatttataatctgattggaattcctatagctgctggagtttttatgcccatt
ggtttggttttgcaaccctggatgggatctgctgcaatggctgcttcatctgtttcagta
gtactttcttcactcttccttaaactttacaggaaaccaacttatgagaattatgaacta
catgctcgaaaccaaatgggacagaaaagtccttcagaaataagtgttcatgttggaata
gatgatacctcaagaaattctcctaaactgggtttgctggaccgaattgttaattacagc
agagcctccataaattcactactgtctgataaacgatcactaaacagcgttggtaccagt
gaacctgacaagcactcactcctggtcggagactgcagggaagatgacgacagtgcgttg
taa

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