Bos taurus (cow): 614333
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Entry
614333 CDS
T01008
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 precursor
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
bta
Bos taurus (cow)
Pathway
bta05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
614333 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
bta01002
]
614333 (BACE1)
Enzymes [BR:
bta01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
614333 (BACE1)
Peptidases and inhibitors [BR:
bta01002
]
Aspartic peptidases
Family A1: pepsin family
614333 (BACE1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
614333
NCBI-ProteinID:
NP_001039996
BGD-bta:
BT25553
Ensembl:
ENSBTAG00000019365
VGNC:
26400
UniProt:
Q2HJ40
V6F9A9
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All DBs
Position
15:complement(27972060..27993773)
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AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGSGVLPAHGSQPGIRLPLRSGLGGAPLGLRLPRETDEESEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTLGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEALASVGGSMIIGGI
DHSLYMGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcgctgccctggctccttctgtggatgggctctggggtgctgcctgcccac
ggctcccagcccggcatccggctgcccttgcgaagcgggctggggggtgcccccctgggg
ctgcggctgccccgggagaccgacgaggagtctgaggagcccggccggaggggcagcttt
gtggagatggtggacaacctgaggggcaaatccggccagggctactacgtggagatgacc
ttgggcagccccccacagacgctcaacatcctggtggacacaggcagcagtaacttcgca
gtaggggccgccccccaccctttcctacaccgctactaccagaggcagctgtccagcacg
taccgggacctccggaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggtaccgacctggtgagcatcccccacggccccaacgtcaccgtgcgcgccaacatt
gctgccatcacggaatcagacaagttcttcatcaacggctccaactgggagggcatcctg
gggctagcctacgcggagatcgcccggcccgatgactccctggagccattctttgactcc
ctagtgaagcagacccacgtgcccaatctcttctcactgcagctctgtggcgctggcttc
cccctcaaccagtcggaagcgctggcctcagttggagggagcatgatcattgggggtatc
gaccactcgctgtacatgggcagcctctggtatactcccatcaggcgggagtggtattat
gaggtgatcattgtacgggtggagatcaatggacaggatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgttgacagtggcaccaccaaccttcgattacccaagaaa
gtgttcgaagctgctgtcaaatccatcaaggcagcctcctcgacggagaagttcccagac
ggtttctggctaggggagcagctggtgtgctggcaagcaggcaccaccccatggaacatt
ttcccagtcatctcactctacctaatgggtgaggtcaccaaccagtccttccgcatcacc
atccttccacagcaatacctgcggccagtggaagatgtggccacctcccaagacgactgt
tacaagttcgccatttcacagtcatccaccggcactgtcatgggagcggtcatcatggag
ggcttctacgtggtctttgatcgggcccggaaacgaattggctttgctgtcagtgcttgc
cacgtgcacgatgagttcaggacagcagcggtggaaggccctttcgtcacccccgacatg
gaagactgtggctacaacatcccccagacggatgagtcgaccctcatgaccatagcctac
gtcatggctgccatctgcgcgctcttcatgctgcccctctgcctgatggtgtgccagtgg
cgctgcctccgctgcctgcggcaccagcacgacgactttgctgatgacatctccctgctg
aagtga
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