Bos taurus (cow): 615059
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Entry
615059 CDS
T01008
Symbol
HTT
Name
(RefSeq) huntingtin isoform X1
KO
K04533
huntingtin
Organism
bta
Bos taurus (cow)
Pathway
bta05016
Huntington disease
bta05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
615059 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
615059 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
bta03019
]
615059 (HTT)
04131 Membrane trafficking [BR:
bta04131
]
615059 (HTT)
03029 Mitochondrial biogenesis [BR:
bta03029
]
615059 (HTT)
Messenger RNA biogenesis [BR:
bta03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
615059 (HTT)
Membrane trafficking [BR:
bta04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
615059 (HTT)
Mitochondrial biogenesis [BR:
bta03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
615059 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_2
HEAT_EZ
HEAT_EF3_N
Motif
Other DBs
NCBI-GeneID:
615059
NCBI-ProteinID:
XP_002688476
BGD-bta:
BT10429
Ensembl:
ENSBTAG00000001506
VGNC:
30007
UniProt:
E1B8E7
LinkDB
All DBs
Position
6:complement(115600431..115724146)
Genome browser
AA seq
3129 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQQQQQQQPPPPPQPPQPPQPPPQAQPPPQPPPPPPPL
GPAAAEEPLHRPKKELSATKKDRVHHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCS
DDAESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHL
VRPQKCRPYLVNLLPCLTRTSKRPEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFI
ANLKSSSPTVRRTAAGSVVSICQHSRRTQYFYSWLLSVLLGLLVPVEGEHPTLLILGVLL
ALRYLVPLLQQQVKDTSLKGSFGVTRKEMEVSPSTEQLVQVYELTLHYTQHQDHNVVTGA
LELLQQLLRTPPPELLRALTTAGGVRQLAASKDEPGGRSRSGSIVELIAGGGSSCSPVLS
RKQKGKVLFGEAAPLEDDSEPRSEGSSPAFSASVKGEVGGELAASSGISTPGSASSAADS
VGHDIITEQPRSQHTLQTDAVDLAACDLTSAATDGDEEDILSHSSSQMSAVPSDPAMDLN
DGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGTDSQYPGMQVGQTQDEDEDATAVL
PDEDAEAFRNSSIALQQAHLLKSMGHCRQSSDSSVDKFVSREEAAEPGDPENKPCRVKGD
IGQSTDEDSAPLVHCVRLLSASFLLTGEKNALVPDRDVRVSVKALALSCIGAAVALHPES
FFSKLYRAPLDTVEYPEEQYVSDVLNYVDHGDPQVRGATAILCGTLICSVLGRCRFHVAG
WMGAVRARTGNTFSLADCIPLLQKTLKDESSVTCKLACAAVRLCVMSLCSSSYSAWGLQL
ITNLLALRSSSYWLVRTELLETVAEIDFRLVSFLEAKAESLHRGAHHYTGLLKLQERVLS
NVVIHLLGDEDPRVRHVAAASLMRLVPKLFYKCDQGQADPVVAVARDQSSVYLTLLMHET
QPPSHFSVSAVTRIYRGYNLLPSITDVTLENNLSRVIAAVSHELITSTTRALTFGCCEAL
CLLSTAFPVCIWSLGWHCGVPPLSASDESRKSCTVGMVSMILTLLSSAWFPLDLSAHQDA
LILAGNLLAASAPRSLRSSWASEDEASTAATKQEEAWPALGDRTLVPMVEQLFSHLLKVI
NICAHVLDDVAPGPAVKAALPSLTNPPSLSPIRRKGKEKEPGEQASVPVSPKKGSEASPA
SRPPETSGPVATNKSSSLGSFCHLPSYLKLHDVLKATHANYKVTLDLQSSGEKFGGFLRS
ALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTLFGTNLASQLD
GLSSHASKSQGRAQRLGSSSARPGLYHYCFMAPYTLFTQALADASLRNAAQAEQDQDTAG
WFDVLQKVSTQLKTNLTSVTKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQKQVL
DLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERY
HSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKE
VVVSMLLRLIQYHQVLEMFTLVLRQCHKESEDRWKRLSRQVADVILPMLAKQQMHIDSHE
ALGVLNTLFEILAPSSLRPVDMLLRSMFVTPDTLAAVSTVQLWVSGILAILRVLISQSTE
DIVLSRIQELSFSPYLVSCPTISRLRDGDSTSALEEHTEGRQMKNLPEETFARFLLQLVG
VLLEDIVTKQLRVEVSEQQQTFYCQELGTLLMCLIHIFKSGTFRRITAAASRLLRDGADG
GFYGLESLNAWVRSMVPTHPALVLLWCQILLLVSHTDYRWWAEVQQTPKRRSLSSTKSLS
PETSGEDEDPDVASKLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLINL
SHEPPVQDFISAIHRNSAASGLFIQAIQSRCENLSTPTMLKRTLQCLEGIHLSQSGAVLM
LYVDKLLCTPFRVLARMVDTLACRRVEMLLAANLQSSTAQLPAEELIRIQEHLQSSGLAQ
RHQRLYSLLDRLRLATAPGSHGPTPPVTSHPLDGDGPLALEAVNPDKDWYVQLVKAQCWT
RSDSALLEGAELVSRIPAGDLGAFMMHSEFNLSLLAPCLGLGMREISGGQESPLFEAART
ATLDRVTVVVQQLPAVHEAFQPFLPTQPSAYWSKLDDLFGDAALYRTLTTLAQALAQYLL
VFSKLPSHLHLPPEKERDTVKFMVMTVEALSWHLIHSRVPLSLDLQAGLDCCCLALQLPG
LWSLLAAPDMVTHACSLIHCVRFILEAIVVQPGDQLLSPERRTSTPKAAREDSVDSDTQN
PQYITAACGMVAEMVECLPSVLALGHKRNSRTPAFLTPVLRNIVISLARLPLVNSYMRVP
PLVWKLGWSPKPGGDFGTVFPEIPVEFLQEKEVFREFIYRINTLGWTSRTQFEETWATLL
GVLVTQPLMMEQEESPPEEDVERTQIHVLAVQAITSLVLSAMTVPVAGNPAVSCLEQQPR
NKPLKALDTRFGRKLSIIRGIVEQEIQAMVSRRENAATHHLYQAWDPVPSLAPATTGALI
SHDKLLLQLNPERELGDMSYKLGQVSIHSVWLGNSITPLREEEWDEEEEETEAPAPSSPP
TSPINSRKHRAGVDIHSCSQFLLELYSRWILPSSSARRTPVTLISEVVRSLLVVSDLFTE
RSQFETMYLTLTELRKVHPSEDEILLQYLVPATCKAAAVLGMDKAVAEPVSRLLESALRS
SHLPSTMGALHGVLYVLECDLLDDTAKQLVPVVTDYLLSNLQGRAHCVSVHSQQHVLVMC
ATAFYLIENYPLDVGPDFSASVIQMCGVMLSGSEEATPSVVYHCVLRGLERLLLSEQLSR
LDAESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKVSPGRASEPSTAAPDSESVIV
AMERVSVLFDRIRKGFPCEARVVARVLPQFLDDFFPPQDVMNKVIGEFLSSQQPYPQFMA
TVVYQVFQTLHGAGQSPMVRDWVMLSLSNFTQRSPVAMAMWSLSCFFVSASTSPWVSAIL
PHVVSRMGKLEQVDVNLFCLVATDFYRHQIEEELDRRAFQSVFEVVAVPGNPYHRLLACL
RSVQKAAAC
NT seq
9390 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccctggaaaagctgatgaaggccttcgagtccctcaaatccttccagcagcag
cagcagcagcagcagcagcagcagcagcagcctccgccgccgcctcagccgcctcagccc
cctcagccgccgccgcaggcgcagccgccgcctcagccgcccccgccgccgccgccgctt
ggccctgccgcggccgaggagccgctgcaccgaccaaagaaggagctctcagccaccaag
aaagaccgtgtgcaccactgtctgaccatctgtgagaacatagttgctcagtctctcaga
aattctccagaatttcagaaacttttgggcatcgctatggaactttttctgctgtgcagt
gacgacgcggagtcagatgtcaggatggtggctgacgaatgcctcaacaaggtcataaaa
gctttgatggattctaatcttccgaggttgcagctagaactctataaggaaattaaaaag
aacggcgcccctcggagcctgcgcgctgccctctggaggtttgccgagctggctcacctg
gtccggcctcagaaatgcaggccgtacttggtgaacttgttgccttgcctgacacgcaca
agcaagagacctgaggagtctgttcaggagacgttggcggcagcgatccctaaaattatg
gcttcttttggcaactttgcgaacgacaatgagattaaggttctgttgaaggctttcatc
gcgaacctgaagtccagctccccaactgtgcggcggacagcagcgggctcggtggtcagc
atctgccagcactccaggaggacgcagtacttttacagctggctgctcagcgtgctccta
ggtttgctggtccccgtggagggggagcaccccaccctcctgattctcggcgtcctgctc
gcgctgaggtacttggtgcccctgctgcagcagcaggtcaaggacacaagcctgaaaggc
agctttggggtgacgcggaaagagatggaagtctctccctcgacggagcagctcgtccag
gtgtacgagttgaccttgcactacacccagcaccaggaccacaacgtcgtgactggggcc
ctggagctgctgcagcagctcctccgaaccccgccgcccgagctcctgcgcgcgctgacc
acggcgggcggcgtccggcagctcgcggcctccaaggatgagcccgggggccgcagtcgg
agcgggagcatcgtggagctgatagctggagggggttcttcatgcagccctgtcctttca
agaaaacaaaaagggaaagtgctctttggagaagcagcgcccttggaagacgactcggag
cccaggtcggagggcagcagccccgccttctcagcctcagtcaagggtgaggttggaggc
gagctggctgcctcttccgggatctccacgcctggctctgccagctcagcggccgactct
gtgggtcacgacatcatcaccgagcagccccggtcgcagcacacgcttcagacggacgcg
gtggatctggccgcctgtgacttgacaagcgccgccaccgatggggacgaggaggacatc
ctgagccacagctccagccagatgagcgccgtcccttctgaccccgccatggacctgaac
gacgggacccaggcctcctcgcccatcagcgacagctcccagaccaccaccgaggggccc
gattcagccgtgaccccttccgacagttctgaaattgtcttagatggcaccgacagccag
tatccagggatgcaggtggggcagacgcaggacgaggacgaggacgccaccgccgttctt
cctgacgaagacgcggaggctttcagaaactcttccatcgcccttcaacaagcacatttg
ttgaaaagcatgggccactgcaggcagtcctctgacagcagtgtggataaatttgtctca
agagaggaagctgccgagccaggggatccagagaacaagccttgccgggtcaaaggcgac
atcggccaatccactgacgaggattctgcccctcttgtccattgcgtccgccttttgtcc
gcttcatttctgctcacaggggaaaagaatgccttggttccggacagggacgtgcgggtc
agcgtgaaggcgctggccctcagctgcattggagccgccgtggcccttcatcctgagtct
ttcttcagcaaactctacagagcacctcttgacaccgtggaataccctgaggagcagtac
gtgtccgacgtcttgaactatgtcgaccacggggacccgcaggtccggggagccacagcc
atcctctgcgggaccctcatctgctctgtcctcggccggtgccgcttccacgtggcgggc
tggatgggcgccgtcagagcccggacaggaaatacattttctctggcggactgcattccc
ctgctgcagaaaactttgaaggacgaatcatcagttacttgcaagttggcttgtgctgct
gtgaggctctgtgtcatgagcctctgcagcagcagctacagtgcctgggggctgcagctc
atcaccaacttactggccctgcggagcagctcctactggctggtgcggacggagcttctg
gagaccgtggcagagatcgacttcaggttggtgagctttctggaggccaaagcagaaagc
ctgcacagaggggcccatcactatacagggcttttaaaactgcaagagcgggtactcagt
aatgttgtcatccatctgcttggagatgaagaccccagggtgcggcatgttgctgcagct
tcgttgatgaggctcgtcccaaaactgttttacaagtgcgaccaaggacaagcggaccca
gtggtggccgtggcacgagaccagagcagtgtgtacctgacgcttctcatgcacgagacg
cagcctccctcccacttctccgtcagcgccgtaaccagaatttatagaggctataacctg
ttaccaagcatcacagatgtcactctggaaaataacctctctagagtcattgcagcggtt
tctcatgaactgatcacatcgaccacgagggcactcacatttggatgctgtgaagctctg
tgtctactttcaactgccttcccagtttgcatttggagtttgggttggcactgcggagtg
cccccgctgagtgcctcagacgagtccaggaagagctgcaccgtggggatggtctcgatg
atcctgaccctgctgtcgtctgcctggttcccgctggatctctccgcccaccaggatgct
ctgatcttagccgggaacttgctggcagccagtgcccccaggtctctgaggagctcgtgg
gcctctgaagatgaggccagcacggcagccaccaagcaggaggaggcgtggccggccctg
ggtgaccggaccctggtgcccatggtggagcagctcttctcccacctgctgaaggtcatc
aacatctgcgcacacgtcctggatgatgtggctccgggacccgcagtgaaggcagccctg
ccttctctcacaaacccgccttctctgagcccaatccgacggaaagggaaagagaaggag
ccaggagagcaggcgtctgtgcctgtgagtcccaagaaaggcagcgaggccagtccagcc
tctcggccacctgaaacctcggggcctgtcgccacaaacaagtcctcgtcactgggaagc
ttctgtcacctgccttcttacctcaaactgcacgacgtcctgaaagccactcacgccaac
tacaaggtcaccttggatcttcagagcagcggcgagaagtttgggggcttcctgcgctct
gccttggacgttttgtctcagattctggagctggcgacgctgcaggacatcgggaagtgt
gttgaagagattctgggatacctgaagtcttgcttcagtcgagagccaatgatggcgacc
gtgtgtgttcagcagttgctgaagactctgtttggaacaaacctggcctcccagttggac
ggcctgtcttcgcacgccagcaagtcgcagggccgtgcgcagcgcctcggctcctccagc
gcgcggcccggcttgtaccactactgcttcatggcaccgtacaccctcttcacccaggcc
ttagcggacgccagcctgcggaacgcggcgcaggcagagcaggaccaggacaccgcaggg
tggtttgacgtcctccagaaagtgtcaacccagctgaagacaaacctcaccagcgtcaca
aagaaccgagcagacaagaatgctattcacaatcacattcgcttgttcgagcctcttgtt
ataaaggctttgaagcagtacacgaccaccacctccgtgcagctgcagaagcaggtgctg
gacctgctggcgcagctggtgcagctgcgggtcaactactgcctcctggactcagaccag
gtgtttattggatttgtgctgaagcagtttgaatacattgaggtcggccagttcagggag
tcagaggcgattatcccaaacatctttttcttcctggtattactgtcttacgagcgttac
cactcaaaacagatcatcgggatccctaaaatcatccagctctgtgacggcatcatggcc
agcgggaggaaggcagtgacgcacgccatacctgccctgcagcccatagtccacgacctc
ttcgttttaagaggaaccaataaggctgatgcaggaaaagagcttgaaacccagaaagag
gtggtggtgtccatgttactgagactcatccagtaccatcaggtgctggagatgttcacg
ctggtcctgcggcagtgccacaaggagagcgaggacaggtggaagcggctgtcccggcag
gtggccgacgtcatcctcccgatgctggccaagcagcagatgcacattgattctcacgag
gccctgggagtgctgaacacgttgtttgagattttggccccctcctccctacgccctgtg
gacatgcttttacggagtatgttcgtcaccccagacaccctggcagcggtgagcacggtc
cagctgtgggtgtcaggcatcctggccatcctgcgggtgctgatttcccagtcgaccgag
gacatcgtcctgtcccgcatccaggagctctccttctctccgtacttggtctcctgtccg
acaatcagtaggttaagagatggggacagtacttcagcactggaggagcacactgaaggg
agacagatgaagaatctgccggaagaaacatttgccaggtttctgctccagctggttgga
gtcctcttagaggacattgttacaaagcagctgagagtggaggtgagcgagcagcagcag
actttctactgccaggagctgggcacgctgctcatgtgtctcatccacatcttcaagtcc
gggacgttccggaggatcaccgcagctgcctcgaggctcctgagggacggcgcggacggc
ggcttctatggcctggagagcctgaacgcgtgggtgcgctccatggtccccacgcacccg
gccctggtgctgctctggtgtcagatcctgctgctcgtcagccacaccgactaccgctgg
tgggcagaggtgcagcagacccccaaaagacgcagcctgtccagcacgaagtcgctgagt
ccggagacatctggagaggacgaggatccggacgtggcttccaagctggggatgtgcaac
agagagatcgtgcggagaggcgccctcattctcttctgcgactacgtctgccagaacctg
catgattcggagcacttgacatggctcatcgtgaaccacattcaagacctgatcaacctg
tcccacgagcctccggtgcaggacttcatcagcgccatccatcggaattccgctgccagt
ggccttttcatccaggcaattcagtctcgctgtgaaaatctttcaactcccaccatgctg
aagagaacgctccagtgcctggaagggatccacctgagccagtcgggtgccgtgctgatg
ctgtacgtggacaagcttttgtgcacgccgttccgtgtgctggctcgcatggtcgacacc
cttgcttgtcgccgggtggaaatgcttttggccgcaaatttacagagcagcacggcccag
ctgccggcggaggagctgatccggatccaggagcacctgcagagcagcgggttagcacag
agacaccagaggctctactccctgctggacaggcttcgtctcgccaccgcaccggggtcg
catggccccacgccccccgtcacgtcccaccccctggacggggatgggcccctggcactg
gaggcagtgaatcctgacaaagactggtacgtgcagctggtgaaggcccagtgctggact
cggtcagactctgccctgctggaaggcgcagagctggtgagccggatccctgcgggcgac
ctgggcgccttcatgatgcactcggagttcaacctgagcctgttggcgccgtgcctgggc
ctgggcatgcgtgagatctcggggggccaggagagccccctttttgaagcagctcgcacg
gcaactctggaccgcgtgactgttgtggtccagcagcttcccgccgtccacgaagctttc
cagccgttcctgcccacgcaacccagcgcctactggagcaagctggatgacctctttggg
gatgctgcactgtatcggactctgaccaccctggcccaggccctggcccagtacctgctg
gtgttctccaagctgcccagccatttgcaccttcctcctgagaaagagagggacactgtg
aagttcatggtcatgactgtcgaggcactgtcgtggcacctgatccactcgagggtcccg
ctgagcctggacctgcaggcgggcctggactgctgctgcctggccctgcagctgcccggc
ctctggagcctgctcgccgcgcccgacatggtgacccacgcctgctccctcatccactgt
gtgcggttcatcctggaggccattgtggtgcagcccggggaccagcttcttagtccagaa
agaaggacgagcacccccaaggctgccagagaggacagcgtggattcagacacacagaac
cctcagtacatcactgcagcctgtggcatggtggccgagatggtggagtgcctgccgtcg
gtattggccttgggccacaagaggaacagccgtacgcccgcgttcctcacgccggtgctc
aggaacatcgtcatcagcttggcccgcttgccgctcgtcaacagctacatgcgcgtcccg
cccctggtgtggaaactcggatggtcacccaaaccaggcggggatttcggcacagtgttc
cctgagatccccgtggagttccttcaggagaaggaggtcttcagagagttcatctaccgc
atcaacacgctggggtggaccagccgcacccagtttgaggagacatgggccacccttctc
ggcgtcctggtgactcagccgctcatgatggagcaggaggagagccccccggaagaggac
gtggagaggacgcagatccacgtcctggctgtgcaggccatcacctccctggtgctgagc
gcgatgaccgtgcctgtggctggcaacccggccgtgagctgcctggagcagcagccccgg
aacaagcccctgaaggcccttgacaccaggtttgggaggaagctgagcatcatcagaggg
attgtcgagcaggagatccaggcaatggtttccaggagagaaaacgccgccactcaccac
ctgtaccaggcgtgggaccccgtcccgtctctggccccggccaccacaggtgctctcatc
agccatgacaagctgctgctgcagctcaaccccgagcgtgagctgggggacatgagctac
aagcttggccaggtgtccatccactcggtgtggctggggaacagcatcacgcccttgcga
gaggaggagtgggacgaggaggaggaggagaccgaggccccggcaccgtcgtccccgccc
acatctccgatcaactccaggaaacaccgggctggagtcgacatccactcctgttcgcag
tttttgcttgagttgtacagtcgctggatcctgccgtcgagttccgccaggaggaccccc
gtcaccctgatcagcgaggtagtgcgctcgctcctcgtggtctcggacttgttcactgag
cgcagccagtttgagacgatgtacctgacgctgacggagctgcggaaggtacacccctcg
gaagacgagattcttctgcagtacctggtgcccgccacctgcaaagcagccgctgtcctc
gggatggacaaggctgtggcggaaccggtcagccggctgctggagagcgcgctccggagc
agccacctgcccagcacgatgggtgccctgcacggcgtcctgtacgtgctggagtgcgac
ctcctggatgacaccgccaagcagctcgtccctgtcgtcaccgactacctcctctccaac
ctccagggtagagcccactgcgtgagcgtgcacagccagcagcacgtgctggtgatgtgc
gccacggccttctacctgatcgagaactacccgctggacgtgggcccggacttctcggcc
tccgtcatacagatgtgtggagtgatgctgtctggaagcgaagaggccaccccgtccgtc
gtctaccactgcgtcctgcggggcctggagcgcctccttctctccgagcagctctcccgg
ctagacgcagagtccctggtcaagctgagcgtggaccgggtgaatgtgcacagcccgcac
cgcgccatggcggccctgggcctcatgctcacctgcatgtacacaggaaaggagaaagtc
agtccaggccgagcctccgagcccagcactgccgcccccgacagcgagtccgtgatcgtg
gccatggagcgggtgtctgtcctctttgacaggatccggaaggggttcccctgcgaagcc
cgcgtggtggcacgcgtcctgccccagttcctggacgacttcttcccgccccaggacgtc
atgaacaaggtcatcggcgagttcctgtccagccagcagccatacccgcagttcatggcc
accgtcgtgtaccaggtgttccagacgctgcacggcgcggggcaatcgcccatggtgcgg
gactgggtcatgctgtccctctccaacttcacgcagcggagcccagtcgccatggccatg
tggagtctctcctgcttcttcgtcagcgcgtccaccagcccgtgggtctcggcgatcctc
ccgcacgttgtgagcaggatgggcaagctggagcaggtggacgtgaacctcttctgcctg
gtggccacggacttctaccgacaccagatagaggaggagctcgaccgcagggccttccag
tccgtgttcgaggtggtcgccgtgcccggaaacccataccaccgcctgctggcttgtctg
cggagcgtccagaaggccgctgcatgctga
DBGET
integrated database retrieval system
