Bos taurus (cow): 782201
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Entry
782201 CDS
T01008
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
bta
Bos taurus (cow)
Pathway
bta00520
Amino sugar and nucleotide sugar metabolism
bta00541
Biosynthesis of various nucleotide sugars
bta01100
Metabolic pathways
bta01250
Biosynthesis of nucleotide sugars
Module
bta_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
782201 (GNE)
00541 Biosynthesis of various nucleotide sugars
782201 (GNE)
Enzymes [BR:
bta01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
782201 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
782201 (GNE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
FGGY_N
DRTGG
Glucokinase
Motif
Other DBs
NCBI-GeneID:
782201
NCBI-ProteinID:
NP_001178072
BGD-bta:
BT24400
Ensembl:
ENSBTAG00000001142
VGNC:
56970
UniProt:
F1MIL9
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Position
8:complement(60494277..60554131)
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AA seq
722 aa
AA seq
DB search
MEKKENNRKLRVCVATCNRADYSKLAPIMFGIKMEPEFFELDVVVLGSHLIDDYGNTYRM
IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA
TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL
AGCPSYDKLLSAKNKDYMSIIRMWLGDDVKPKDYIVALQHPVTTDIKHSIKMFELTLDAL
ISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN
SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKI
YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKDNISQDIDHILETLSALAVDLGGTNLR
VAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNP
REGIVLHSTKLIQEWNSVDLRSPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTL
ITGTGIGGGIVHQHELIHGSSFCAAELGHIVVSLDGPDCSCGSHGCIEAYASGMALQREA
KKLHDEDQLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTM
NPSLVILSGILASHYIHTVKDVIRQQALSSVQDVDVVVSDLVEPALLGAASMVLDYTTRR
IY
NT seq
2169 nt
NT seq
+upstream
nt +downstream
nt
atggagaagaaagagaataaccggaagcttcgggtttgtgttgctacttgcaaccgtgct
gattattctaaacttgcccccatcatgtttggcattaaaatggaacctgagttctttgaa
cttgacgtggtggtacttggctctcacctgatagatgactatggaaacacgtatcgcatg
attgaacaagatgactttgacattaacaccaggttacacacgattgtcagaggggaagat
gaggcagccatggtggagtcagtaggcctggcccttgtgaagctaccagatgtccttaat
cgcctgaaacctgatatcatgattgttcatggagacaggtttgatgccctggctctggct
acatctgctgccttgatgaacatccgaatccttcacattgaaggcggggaagtcagtggg
accattgatgactctatcagacacgccataacaaaactggctcattatcacgtgtgctgc
acccgaagtgcagagcaacacctgatatccatgtgtgaggaccatgaccgcatcctgctg
gcaggctgcccttcctacgacaagctgctctccgccaagaacaaagactacatgagcatc
attcggatgtggttaggtgatgatgtaaaacctaaagattacattgtcgcacttcagcac
cctgtgaccactgacattaagcattctataaaaatgtttgaattaacattggatgcactt
atctcatttaacaagcggaccctagttctgtttccaaatattgatgcaggaagcaaagag
atggttcgagtgatgcggaagaagggcattgagcatcatcccaattttcgtgcagttaaa
catgtcccatttgaccagtttatacagctggttgcccatgctggttgtatgattgggaac
agcagctgtggggtacgagaagttggagcttttggaacacctgtgatcaacttaggaaca
cgtcagattggaagagaaacaggggagaatgtccttcatgtccgggatgctgatacccaa
gacaaaatattgcaagcgttgcaccttcagtttggtaaacagtacccttgttcaaagata
tatggggatggaaatgctgttccaaggattttgaagtttctcaaatctattgatcttcaa
gagccactacaaaagaaattttgttttcctcctgtgaaggataacatctctcaagatatt
gaccatattcttgaaactctaagtgccttggctgttgatcttggcgggacgaacctccga
gttgcaatagtcagcatgaagggtgaaatagttaagaagtatactcagttcaatcctaaa
acgtatgaagagaggattaatttaatcctacagatgtgtgtagaagccgcagcagaagct
gtaaaactgaactgcagaattttgggagtaggcatttctacaggtggccgtgtaaatcct
cgggaaggaattgtgctgcattcaaccaaactgattcaagaatggaactccgtggacctc
agaagccccctgtctgacactttgcatctccccgtgtgggtagacaatgatggcaactgt
gctgccctggcagaaaggaaatttggccaaggaaaaggccttgaaaactttgtgacactt
atcacaggcacagggatcggcggggggatcgtccaccagcatgaactgatccacggcagc
tccttctgtgctgcagagcttggccacattgtggtgtccctggatgggcctgattgttcc
tgtggaagccacgggtgcattgaagcatatgcctctggaatggccttgcagagggaagca
aaaaagctacatgatgaagaccagctcttggtggaagggatgtcagtgccaaaagatgaa
gctgtgggcgcactccatctcatccaggctgcaaaacttggcaacgcaaaggcccagagc
atcttgagaacagctggaacagctttaggtcttggggttgtgaacatcctccacactatg
aatccttcccttgtgatcctctctggaatcctagccagtcactacatccacactgtcaaa
gacgtcatccgccagcaagccttgtcctcggttcaggatgtggacgtggtggtttccgat
ttggtggaacctgctctgctcggcgccgccagcatggtcctggactacacgactcgcagg
atctactag
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