Budorcas taxicolor (takin): 128043920 Help Entry 128043920         CDS       T08909                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism btax  Budorcas taxicolor (takin) Pathway btax04072   Phospholipase D signaling pathway btax04115   p53 signaling pathway btax04140   Autophagy - animal btax04150   mTOR signaling pathway btax04151   PI3K-Akt signaling pathway btax04152   AMPK signaling pathway btax04211   Longevity regulating pathway btax04218   Cellular senescence btax04714   Thermogenesis btax04910   Insulin signaling pathway btax04919   Thyroid hormone signaling pathway btax05163   Human cytomegalovirus infection btax05165   Human papillomavirus infection btax05168   Herpes simplex virus 1 infection btax05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:btax00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     128043920 (TSC2)    04151 PI3K-Akt signaling pathway     128043920 (TSC2)    04152 AMPK signaling pathway     128043920 (TSC2)    04150 mTOR signaling pathway     128043920 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     128043920 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     128043920 (TSC2)    04218 Cellular senescence     128043920 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     128043920 (TSC2)    04919 Thyroid hormone signaling pathway     128043920 (TSC2)   09149 Aging    04211 Longevity regulating pathway     128043920 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     128043920 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     128043920 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     128043920 (TSC2)    05163 Human cytomegalovirus infection     128043920 (TSC2)    05165 Human papillomavirus infection     128043920 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:btax01009]     128043920 (TSC2) Protein phosphatases and associated proteins [BR:btax01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      128043920 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  128043920 NCBI-ProteinID:  XP_052492295 LinkDB All DBs Position 2:complement(41273323..41304144) Genome browser AA seq 1847 aa AA seqDB search MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVARTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGILR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMVCLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIHHMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI LLNIIERLLQQLQSLDSPELSAIVHDLLSTVEELCDQNEFHGSQERYFELVERCADQRPE SSVLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS PPPELEERDVAVHSASLEDVKTAVLGLLVILQTKLYALPASHATRVYETLVSHIQLHYKH SYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGLVRFSPYCVCDYLETERSSEKKAG GPLSPPAGPPGPAPAGPAARLGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSAALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDVILKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKELKESSAADAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQGGPELSSDPSVHVRQTKEAPAKLESQAGQQVYHGARDRVRSMSGGHGLRVG ALDAPACHFPGSPTSLGSQTAPAGQPEKASAGSPLPAQKEKTNLAAYVPLLTQGWAEILV RRPTGNTSWLMSLENPLSPFSSDINSMPLQELSNALMAAERFKERRDTALYKSLSVPAAG SAKPSPPPRSNTGSGPCRTGGACPLCSAVRGLPPADGPLTVSLAVASFSSLCQSRCQGKL HRSISWADSAVVLEEGGPGEASLSAEPPELEDFEATLGSDGRCGRSDAFSRSSSTSSQEE KSFHAEELPPGGIPIERAVSSEGSRASVDLAFQPSQPLSKSSSSPELQTLQDILGDPGDK AEVGRLSPEAKARSQSGILDREGAPWSAPGEERRGRGPSQPEGPLPSSCPRSPSGLRPRG YTISDSAPSRRGKRVERDAFKSQAGTSNTEKVPGINPSFVFLQLYHSPFFGDESNKPILL PNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGKLI ELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLG NDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQCRKDMEGLVDTSMAKI VSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRIREEAHYSS ASLPLMQTHPPGHAKALAQAPAESTPAYETGQRKRLVSSVDDFTEFV NT seq 5544 nt NT seq  +upstreamnt  +downstreamnt atggctaagccaacaagcaaagattcaggcttgaaggagaagttcaagattctgttggga ctggggactccacggccaaaccccaggtctgcagagggcaagcagactgagtttatcatc accgcggaaatcctgagagagctgagtgttgaatgtggcctcaataatcgcatccgggtg atagggcagatctgtgaggttgccagaacgaagaaattcgaagagcacgcggtggaagca ctctggaaggctgtctcggacctgctgcagccagagcggccacccgaggcccggcatgcg gtgctggctctgctgaaggccattgtgcagggacagggggaccgcctgggcattctcagg gccctcttcttcaaggtcatcaaggattacccctctaatgaagacctccacgagagactg gaagttttcaaggccctcacagacaatgggagacacatcacctacttggaagaagagctg gcggactttgtcctgcagtggatggacgttggcctgtcctccgaattcctcctggtgctc gtgaacttagtcaagttcaacagctgttaccttgatgaatacatcgcctccatggtccac atggtctgcctgctctgtgtccagaccgtgtcctctgtggacatagaggtgtctctgcag gtgctggatgctgtggtttgctacaattgtctgccagccgagagcctccccctgttcatc gtcaccctctgccgcaccatcaacgtcaaggagctctgtgaaccttgctggaagctgatg cgcaacctcctgggcacccacctgggccacagcgccatccaccacatgtgccgtatcatg gaagacagagcctacatggaggacgcaccgctgctgagaggagccgtgttctttgttggc atggctctctggggtgcccaccggctctattctctcaagaactccccaacatctgtgttg ccatcgttttatgaggccatgacctgtccgaatgaggtggtgtcctatgagattgtcctc tccataaccagacttatcaagaagtataggagggagctccaggccgtgacctgggacatc ctgctaaacatcatcgagcgcctgctccagcagctccagagcctggacagtccagagctg agcgccatcgtgcacgacctgctgagcacagtggaggagctgtgcgaccagaacgagttt cacggctcgcaggagagatactttgagctcgtggagaggtgtgcggaccaaaggcctgag tcgtccgtcttaaacttaataacctacagggctcagtccatccatccagcgaaggatggc tggatccacaacctgcagctgctgatggagaggttcttcaggaacgagtcacgtagcgct gtgcgcatcaaggtgctagacgtcctgtccttcgtgctgctcatcaacaggcagttctat gaggaagagcttatcaactcagtggtcatctcgcagctctcccacatccctgaggataga gaccaccaggtccggaagctggccactcagctgctggtagatctggctgaaggctgccac acccatcacttcaacagcttactggacatcattgagaaagtgatcgcccgctccctctct ccgccccctgagctggaggagagggatgtggccgtgcactcagcctccttggaggatgtg aagactgcggtcctggggctcctggtcatccttcagaccaagctgtatgccctgcccgcc agccatgccacacgtgtgtatgagacgctggtcagccacattcagctccactacaagcac agctacaccctgcccattgccagcagcatccgtctgcaggccttcgacttcctgctgcag ctacgggccgactcactgcaccgcctgggcctgcccagcaaagacgggctcgtgaggttc agcccctactgcgtctgtgactacctggagacagagaggagctccgagaagaaggccggg gggccgctgtccccgcctgccgggccccctggccccgcacccgcgggccctgccgcgcgc ctcggctccctgccctactccctgctcttccgtgttctgctgcagtgtctgaagcaggag accgactggaaggtgctgaagcttgtgctcagcaagctgcccgagtcgctgcgctataag gtcctcatcttcacctccccgtgcagcgtcgaccagctgtccgccgccctctgctccatg ctttcaggtcccaagaccctggagcggctccgaggcaccccagaaggcttctccaggacc gacctgcatcttgctgtggttcccgtgctgacagccctgatctcttatcataactacttg gacaaaaccagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgt gccagccagtgtgtggtggccctggccgtatgcagcgtggagatgcctgacgtcatcctc aaggcgctgcctgtcctggtcgtgaagctcacacacatctcggccacggccagcatggcc atcccgctcctcgagttcctgtccactctggccaggctgcctcacctctacaggaacttc gcagcagagcagtatgccagtgtgtttgccatctccctgccatataccaacccctccaag ttcaatcagtatatcgtgtgcctggcccatcacgtcatagccatgtggttcatcaggtgc cgcctgcccttccggaaggactttgttccttacatcaccaagggtctgcgctccaacgtc ctcctgtcttttgatgacactcccgagaaggacagcttcagagcgcggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaactcaaggagagctctgcagccgatgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggattcagacctctctcacgagcgccagcttg gggtctgcagatgagaactcgatggcccaggccgacgacaacttgaaaaacctccacctg gagctcacagagacgtgtctggacatgatggccagatacgtgttctccaatttcacggca gtccccaagaggtcccctgtaggagagttcctcctggctggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcaccgtgacgacgagcgtgggaaccgggacccggtcactg ctaggcctggactcgggagagctccagggcggcccggagttgagctctgaccccagcgtg cacgtgagacagacaaaggaggcccccgccaagctggagtcccaagctgggcagcaggtg taccacggagcccgggaccgggtccgttccatgtccgggggccatggccttcgcgtgggt gccttggacgctccagcctgccacttccctggcagccccacatccctgggctcccagact gctccagccggccagcccgagaaggcctcagctggcagcccgctcccagcgcagaaggag aagacaaacctggctgcttacgtgcccctgctgacccagggctgggcggagatcctggtc cgcaggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccccttc tcctcggacatcaacagcatgccgctgcaggagctgtccaatgccctcatggctgccgag cgcttcaaggaacgccgcgacacagccctgtacaagtcgctgtcagtgccggcggccggc tcggccaagccatccccgcccccacgctccaacacaggctcgggtccttgcaggaccggc ggtgcctgtcctctctgctcggctgtgcgtggccttcctcctgctgacgggccgctcacg gtttcccttgcagtggcctctttctcctccctgtgccagtccaggtgccaaggaaagctg cacaggagcatttcctgggcagattccgcggtagtcctggaggagggaggtccaggcgag gccagtttgtctgcagagcctcccgagttggaagactttgaggcaacactgggctccgat gggcgctgtgggcgcagcgacgctttcagcaggtcatcttccacctccagccaggaggag aagtcattccatgccgaggagttgcctcctgggggcatccccatcgagcgggcggtctcc tcggagggctcccgggcctccgtggacctcgccttccagccctctcagcccctgagcaag tccagctcgtcgcctgaactgcagaccctgcaggacatcctgggggaccctggggacaag gctgaggttggccggctgagccctgaggccaaggctcggtcgcagtcagggatcctggac agggaaggtgctccctggtcagccccgggtgaggaacgccggggccggggcccctcccag ccagagggccccctgccttccagctgtccccgctcccccagtgggctgcggccccgaggc tacaccatctcggattcggccccgtcacgcaggggcaagagggtggagagggatgccttc aagagccaggcagggacctccaacaccgagaaggtgccgggcatcaaccccagctttgtg ttcctgcagctctaccactcaccgttcttcggtgacgagtccaacaagccaatccttttg cctaatgagtctttcgaacggtcagtgcagctccttgaccagatcccgtcatacgacacg cacaagatcgcggtcctgtacgtgggagaaggccagagcaatagcgagctcgccatcctg tccaatgagcacggctcctacaggtacacagagttcctcacagggctgggcaagctcatc gagctcaaggactgccagccggacaaggtgtacctgggcggcctggacgtgtgcggcgag gacggccagttcacctactgctggcatgacgacatcatgcaagcggtcttccacatcgcc accctgatgcccaccaaggacgtggacaagcaccgctgtgacaagaagcgccacctgggc aacgacttcgtgtccatcgtctacaatgactctggcgaggatttcaagttgggcaccatc aagggccagttcaacttcgtccacgtgattatcacgcccctggattacgagtgcaacctg gtgtctctgcagtgcaggaaagacatggagggccttgtggacaccagcatggccaagatc gtgtctgaccgaaacctgcccttcgtggcccgccagatggccctgcacgcaaacatggcc tcgcaggtgcaccatagccgctccaaccccaccgacatctacccctccaagtggatcgcc aggctccgccacatcaagcggctgcgccagcggatccgtgaggaagcccactactcaagc gccagcctgcccctgatgcagacacaccctcctggtcatgccaaggctctggcacaggcc ccagccgagtccacgcctgcctatgagacaggccagcggaagcgcctggtctcctctgtg gatgatttcactgagttcgtgtga

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