Budorcas taxicolor (takin): 128044816 Help Entry 128044816         CDS       T08909                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism btax  Budorcas taxicolor (takin) Pathway btax01521   EGFR tyrosine kinase inhibitor resistance btax04151   PI3K-Akt signaling pathway btax04217   Necroptosis btax04380   Osteoclast differentiation btax04550   Signaling pathways regulating pluripotency of stem cells btax04620   Toll-like receptor signaling pathway btax04621   NOD-like receptor signaling pathway btax04630   JAK-STAT signaling pathway btax04658   Th1 and Th2 cell differentiation btax04659   Th17 cell differentiation btax05140   Leishmaniasis btax05145   Toxoplasmosis btax05152   Tuberculosis btax05160   Hepatitis C btax05161   Hepatitis B btax05162   Measles btax05163   Human cytomegalovirus infection btax05164   Influenza A btax05165   Human papillomavirus infection btax05166   Human T-cell leukemia virus 1 infection btax05167   Kaposi sarcoma-associated herpesvirus infection btax05168   Herpes simplex virus 1 infection btax05169   Epstein-Barr virus infection btax05171   Coronavirus disease - COVID-19 btax05200   Pathways in cancer btax05203   Viral carcinogenesis btax05212   Pancreatic cancer btax05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:btax00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     128044816 (JAK1)    04151 PI3K-Akt signaling pathway     128044816 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     128044816 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     128044816 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     128044816 (JAK1)    04621 NOD-like receptor signaling pathway     128044816 (JAK1)    04658 Th1 and Th2 cell differentiation     128044816 (JAK1)    04659 Th17 cell differentiation     128044816 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     128044816 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     128044816 (JAK1)    05203 Viral carcinogenesis     128044816 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     128044816 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     128044816 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     128044816 (JAK1)    05161 Hepatitis B     128044816 (JAK1)    05160 Hepatitis C     128044816 (JAK1)    05171 Coronavirus disease - COVID-19     128044816 (JAK1)    05164 Influenza A     128044816 (JAK1)    05162 Measles     128044816 (JAK1)    05168 Herpes simplex virus 1 infection     128044816 (JAK1)    05163 Human cytomegalovirus infection     128044816 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     128044816 (JAK1)    05169 Epstein-Barr virus infection     128044816 (JAK1)    05165 Human papillomavirus infection     128044816 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     128044816 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     128044816 (JAK1)    05140 Leishmaniasis     128044816 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     128044816 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:btax01001]     128044816 (JAK1) Enzymes [BR:btax01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      128044816 (JAK1) Protein kinases [BR:btax01001]  Non-receptor tyrosine kinases   JAK family [OT]    128044816 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  128044816 NCBI-ProteinID:  XP_052493212 LinkDB All DBs Position 3:80385602..80518858 Genome browser AA seq 1159 aa AA seqDB search MQYLNIKEDCSAMAFCAKMRSSKKAEMNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEL CIRAAQECCISPLCHNLFALYDENTRLWYAPNRTISVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKVQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHPNDSGNVLCYEVMVTGNLGIQWRQKPHIVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVLGIQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDITQGEHLGRGTRTHIYSGT LTDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQHMRKCWEFQPSNRTT FQNLIEGFEALLRSMSNNS NT seq 3480 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaacataaaagaggactgcagtgccatggctttctgtgctaaaatgagg agctccaagaaggcggagatgaatctggaggcccctgagccgggggtggaggtgctcttc tacctgtcggatagggagcctctccggctgggcggcggagagtacacagcggaggagctg tgcatccgggcggcgcaggagtgctgtatctctcctctgtgtcacaacctctttgccctg tatgatgagaacaccaggctctggtatgctccgaatcgcaccatcagcgtcgatgacaaa acatcactccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat gacaacgaacagtcagtatggcgacattctccaaagaagcagaaaaatggctatgagaaa aaaaaagttccagatgcaacacctctccttgacgccagctcactggagtatctgtttgct cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacggagcag gatgggcatgacattgagaacgagtgtctggggatggccgtgctggccatctcccactat gccatgatgaagaaggtgcaattgccagaactccccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctaaaggagtttaacaacaagaccatttgcgacagcagc gtgtccacgcacgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tatggtgctgaaatatttgagacttccatgctactgatttcatcagaaaatgagatgaat tggttccatccaaatgatagtggaaatgttctctgctatgaagtgatggtgactggaaac ctgggaatccagtggagacagaaaccacatattgttcctgttgaaaaggaaaaaaacaaa ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggaaaaaaacaaaatccga gaagagtggaacaatttttcttacttccctgagatcactcacattgtaatcaaggagtct gtggtcagcattaataagcaggacaacaaaaaaatggagctgaagctctcttcccacgag gaggccttgtcctttgtgtccctggtggacggctacttccggctcacggcagatgcccat cactacctctgcactgacgtggctcccccattgatcgtccacaacatacagaatggctgt catggcccaatctgcacggagtatgccatcaataagctgcggcaggaggggagcgaggag gggatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgtcacc tgctttgaaaagtctgaggtgctgggtatccagaaacagttcaagaactttcagattgag gtgcagaagggccgctacagcctgcatggctcggaccgcagcttcccaagccttggggac ctcatgagccacctaaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag cgctgctgccagcccaagccccgagaaatctccaatctgctggtggccaccaagaaagcc caggagtggcagcctgtctaccccatgagccagctgagtttcgatcgaatcctcaagaaa gatattacacaaggcgagcaccttgggagaggcacgcggacacacatctactctgggacc ctcacggattacaaggatgacgaagggacttctgaagagaagagaataaaagtcatcctg aaggtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg atgaggcaggtctcccataaacacatcgtgtacctctatggggtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggaggggggacccctggatctcttcatgcatcgg aaaagtgacgtcctcaccacaccctggaagtttaaagttgccaaacagctggccagcgcc ctgagttacttggaggataaagacctggtccatggaaatgtgtgcaccaaaaacctcctt ctggcccgtgagggcatcgacagtgagtgcggccccttcatcaagctcagtgaccctggc atccccatcactgtgctctccaggcaagagtgcatagaacgaatcccttggatcgctccc gagtgtgttgaagactccaagaacctgagtgtggctgctgacaagtggagctttggaacc acactctgggaaatctgctacaatggcgagatccccttgaaagacaagacgctgattgag aaagagagattctacgaaagccggtgcaggccagtgactccgtcttgtaaggagctagct gacttgatgacccgctgcatgaactacgaccccaaccagagacccttcttccgagccatc atgagagacatcaacaagctggaggagcagaatccagacattgtatcagaaaaaaagcca acaactgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg ggagagggccactttgggaaggtcgagctctgcaggtatgaccctgagggggacaataca ggggagcaggtggctgtcaaatccctgaagcccgagagtggagggaaccacattgctgat ctgaagaaggagattgaaatcttaagaaatctttatcatgagaacatcgtgaagtataaa ggcatctgcacagaagacggtggaaatggtattaagctcatcatggagtttctgccttca gggagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcaatta aaatatgctgttcagatttgtaaggggatggactatttgggttctcggcaatacgttcac cgggacttagcagcaagaaacgtccttgttgagagtgaacaccaagtgaaaattggggac tttggtctaaccaaagccatcgaaactgataaggagtactacacagtcaaggatgaccgg gacagccctgtgttttggtatgctccagaatgtttaattcagtgtaagttttatatcgcc tctgatgtctggtctttcggagtaactctgcatgagctgcttacttactgtgattcagat tccagtcccatggccttgttcctgaaaatgataggcccaactcatggtcagatgacggta acaagactcgtgaatacattaaaagaaggaaaacgcttgccatgtccacctaactgtcca gatgaggtttatcaacatatgcgaaagtgttgggaatttcaaccatctaatcggacaacc tttcagaaccttatcgaaggatttgaagcacttctaagaagcatgagtaataacagttaa

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