Budorcas taxicolor (takin): 128045342
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Entry
128045342 CDS
T08909
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
btax
Budorcas taxicolor (takin)
Pathway
btax00230
Purine metabolism
btax00670
One carbon pool by folate
btax01100
Metabolic pathways
btax01523
Antifolate resistance
Module
btax_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
btax00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
128045342 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
128045342 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
128045342 (GART)
Enzymes [BR:
btax01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
128045342 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
128045342 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
128045342 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
ATP-grasp_3
CPSase_L_D2
Dala_Dala_lig_C
ATP-grasp_LDMS
ATP-grasp_4
RimK
Motif
Other DBs
NCBI-GeneID:
128045342
NCBI-ProteinID:
XP_052493805
LinkDB
All DBs
Position
1:66645955..66674573
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSTHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLNSVGVRCFGPTAEAAQLESSKRFAKEFMDRHGIS
TARWRAFTKPEKACDFIMSADFPALVVKASGLAAGKGVIIAKSKEEACDAVREIMQGKAF
GEAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQEEGMPYTGVLYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNCAAVTVVMASKGYPGDYTKGVEITGFPEA
RALGLEVFQAGTALKDGKVVTNGGRVLTVMAIRESLISALEEARKGLAAIKFEGAVYRKD
IGFRAIAFLQQTRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFTDPLLACGTDGVGTKLKIAQQCGKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLHTTEAVITGIAQACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVANSSLRYSSPAPVGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGRVKAVAHITGGGLLENIPRVLPQKLGVNLDAQTWRVPRIFSWLQHEG
HLSEEEMARTFNCGIGAALVVSEDLVKQTLQDIEQHQEEAWVIGRVVACPEGSPRVKVEH
LIETMQINGSVLENGTLRNHISVQPKKARVAVLISGTGSNLQALIDSTREPSSLAHIVVV
ISNKAAVAGLDKAEKAGIPTRVINHKLYKHRAAFDNAVDEVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGAVCLGENGRICWVTED
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtcattggcagtggaggacgagaacacacgctggcctggaaa
cttgcacagtctactcatgtcaaacaagtgttggttaccccaggaaatgcaggcactgcc
tgctctgagaagatttcaaatactgacatctcaatcagtgatcatactgcccttgcgcag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctagctgct
ggaattgttgggaacctgaactctgtgggagttcggtgctttggccctacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatctca
acagcaagatggagagctttcactaaacctgaaaaagcctgtgacttcattatgagtgca
gacttccccgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtaattatt
gccaagagcaaagaggaggcctgtgacgctgtcagagagattatgcagggtaaagcattc
ggagaagcaggagaaacagttgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggacggactgtggcgcccatgcccccagcacaggaccataagcga
ttgctggagggcgatcagggccccaacacggggggaatgggagcctactgtccagcccct
caggtttctaaggatttgttgctaaaaattaaaaataccattcttcagaggacagtggat
ggcatgcaggaggagggtatgccgtacacaggtgtcctctatgctggtataatgctgacc
aagaacggccccaaagttctggaatttaattgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttagatggcttg
ctctgcacatctctgcctgtttggctggacaactgtgctgccgtaactgtggtcatggca
agtaaaggttacccaggagactacaccaagggtgtagagataacagggtttcctgaggct
cgggctttaggactggaggtgttccaagcaggcactgccctaaaagatggcaaggtggtg
actaacgggggtagggtccttactgtcatggccatcagggaaagtctcatctcagccctt
gaagaagccaggaaaggacttgctgctataaagtttgagggagctgtttataggaaagac
atcggctttcgagccatagctttcctccagcagaccaggggcctgacttacaaggaatct
ggggtagacattgcagctggtaatatgctggtccagaaaattaaacctttagcgaaggcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcactgatcctcttctggcctgtggaacagatggcgttgggacgaaactg
aagattgcccagcagtgcggtaaacatgacaccattggtcaggatttggttgcgatgtgt
gtaaatgacattctggcccaaggagcagagcccctctttttcctcgattacttttcctgt
ggaaaacttgacctccatacgactgaagctgttatcactgggatcgcccaagcttgtaga
aaggctggatgtgctctcctcggaggtgaaacggcagagatgcctgacatgtaccctccc
ggagagtatgatctagctggttttgccgttggcgccatggagcgggatcagaaacttcct
cacctggaaagaatcacggaaggggacgctgttattggaatcgcttcatctggtcttcac
agcaacggattcagccttgtgaggaaaatagtagcaaattcttccctccggtactcttct
ccagcacctgttggttgtggtgaccagaccttaggtgacttacttctaaccccaaccaga
atctacagccactcactgttacctgtcctgcgttcaggacgtgttaaggctgttgcacat
attactggtggaggattactggaaaacatccccagagtcctccctcagaaattgggggtg
aatttagatgcccagacctggagggtccccaggatcttctcatggttacagcatgaaggt
cacctctctgaagaggagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcagaggacctggtgaagcagactctgcaggatatcgagcagcaccaggaagaagcc
tgggtgattggcagagtggttgcgtgtcccgaaggttctcctcgtgtgaaagtcgagcat
ctgattgagaccatgcaaataaatggatcagtactggagaatggaaccctgagaaatcat
atctctgttcaaccgaaaaaggcaagagtagctgtcttaatatctgggacaggatcgaac
ctccaagctctcatagacagcactagggagccaagtagcttggcacacattgtcgttgtg
atctccaacaaagctgcagtggctggcttagataaagcagaaaaagccgggattcccacc
agagtaattaatcataaattatataaacatcgtgcagcatttgacaatgcagttgacgaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttgtct
ggcccctttgtccgaaaatggaatgggaaaatgctcaatatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggacgctggggtcacaatcaccggg
tgcaccgtgcactttgtagctgaagatgtagatgctggtcaaattatcttacaggaagcc
gttccagtgaagaggggtgacactgttgaaactctatctgagagagtaaaattagcagaa
cataaaatatttccctcagccctccagctggtggccagtggagctgtatgtcttggagaa
aatggcagaatctgttgggtcacagaggactga
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