Budorcas taxicolor (takin): 128046656 Help Entry 128046656         CDS       T08909                                  Symbol PCLO Name (RefSeq) protein piccolo   KO K16882   protein piccolo Organism btax  Budorcas taxicolor (takin) Pathway btax04911   Insulin secretion Brite KEGG Orthology (KO) [BR:btax00001]  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     128046656 (PCLO)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:btax04131]     128046656 (PCLO) Membrane trafficking [BR:btax04131]  Exocytosis   Calcium ion-dependent exocytosis    Others     128046656 (PCLO) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-piccolo C2 PDZ FYVE_2 FYVE_CARP1-2 Motif Other DBs NCBI-GeneID:  128046656 NCBI-ProteinID:  XP_052494776 LinkDB All DBs Position 4:39419807..39786859 Genome browser AA seq 5153 aa AA seqDB search MGNEASLEGEGLPEGLAAAAAAAAGGGAGGAGSPLHTVIPAGMEADLSQLSEEERRQIAA VMSRAQGLPKGSVTPAAAEPPSMHRKQELDSSQPPKQPGKPPDPGRPIQPGLSKSRTTDT LRSEQKLPGRSPSTISLKESKSRTDFKEEHKSSMMPGFLSEVNPLSAVSSVVNKFNPFDL ISDPDASQEEASKKQKIAQKEQGKPEGVTKPPSQQQSPKTVPKQPGPVRAPLQQEGSPKS GSSQPPEKSKSQPPETGKPAQGFPQAPQTDQAKLPIQRDVSRPQTKQTDPGRGESAKPSL QSPSKPPIQQGSPGKSPAQQPGPEKRTIPQPGPAKPLAQQLGTAKPLAQAPGAAKSLAHQ PGPQSPAQPPGPAKAPAQQVGTTKPQAQLSGPGKTPPQQPGPTKPPPQQPGPVKPPPQQP GPAKPSPQQPGPAKPPPQQPGPAKPPPQQPGPAKPPPQQPGPVKPPPQQPGPAKPPPQQP GPVKPPPQQPGPAKPLPQQPGPMKPLPQPPGSAKPPPQLPGPAKPPPQQPGPAKPPPQLP GPTKHPPQQPGPVKPSAQQSTKPVSQTGAGKPLQPPTFPSAAQTPVHGLPKTICPLCNTT ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEMKEWLCLNCQMQRALGGNLAPIPS SPQPKPKTTPVPASAVSKPPTPSQQVSPKKDTTPKQDVSKVAESKKPPPLVKQPTLHSPH PVTSQQPPEAESSSKPVPPKEPSVSSEPAKVSMADDKPEQPKTGKPATDIVSSSSTATRP DILGSKIPSKDQEKGTPPLKPDSAKPSQSFPPTGEKISPVDSKVIPRPASDTKIISHPGP TPESKDQKQVDPIQKKDEPKKAQTKMSPKPDTKPMPKGSPTPQVPRPPTGQTAPLSPQPP KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTGGQPGSHS QGGPAAPIKQVPPPSQPPTSQGPPKSTAPPAPAKVLPVKKETKAPVIEKLEPKAEQVSTV KRTETEKKPLPTKDSKPSTAEPQKVVLPPKLEETPKPESACPLCKTELNISSKDPANFNT CTECKKQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDMGKMPPTQAGPKASPMP VPMEQPFQETAMPAPVKVKKKEQEEKPEAEKTISEKVKETSSGEKSTPKETIDQIREESK DKTSAPQEKKSPPEDKKPPSEDKKPLPEEEKPPLEEKKPILKDKKPALEDKKLAPATKAS VLEEEQKRDLLKTQVQIAEVKSEGRVPPEAVEEKKQPRMEMEDLPASAPRRLPKEDDGMT QKIKVQPQAPCVAKPDQTESGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSL GEIPSLIPSDEKDLLKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLVEEKSEK KTQPHEVSPEQPKDQQKTQSLVEKLESTVSEEETKESQEEGDTFKKESQQDIPSRKDQEK PEFVDELATRRQPYDSIEDSSESENSPVPPRKGRTSVGSSSSDEYKQEDSQGSGEDEDFI RKQIIEMSADEDASDSEDDEFIRNQLKEISSSIESQRKEETRGKGKGTAGKHRRLTRKSS ASFDDDAGRRHSWHDEDDETFDESPELKYRETKSQESEELVVAGGGGGLRRFKTIELNST IADKYSAESSQKKTALYFDDEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVS SLDEDSDSSPSHKKGESKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLKEQEKQREL EQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS CSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGGQKALKSAE EIYEEMMHKSQKYKAFPAANERDEMFEKEPLYGGMLIEDYIYESLVEDTYNGSLDSSLLA RQEEENGFLQQTRREQKMRLPEQIYEDPMQKITDLQKEFYELENLHAVLPQEDIVSSSFI IPESHEIVDLGSMVTSTSEEKKLLDADAAYEELMKRQQMQLTPGSSPTQPLIRDDLTEST VDFDRVPDASLTSSVLSGASLTDSTSSTTLSIPDVKITQHFSAEEIEDEYVTDYTREIQE IIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSMTTVYTEPVD IVAKFEDAEDISSSTYFPGSIIDYPEDINIPLDQTTIQDGRTGTDHVVISLSGREPAPVE SVGTKLEGLIADTVSTDSSISEKDAAKKARTETGDGLILEVLEAYRDTRKESEAELTEIS LPDTVFDQTPSSVKTLPMKEQVSTTCFLPEEVLGQAKPASQLPSGTPPIFSLPTKTRPFL RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIHPKKKLAVTAPVTATT AATSLVDSVTTVETTSAPRSNGLPMTKVYTTAPPPVPPKPSLIPSGLVFTHKPEPSKPPL APKPAVPQPPVTTPKLTDTYPKPTGLPLTTSMTLNLVTSADYKLPSPTSPLSPHSNKSSP RFSKSLMETYVVITLPSEPGTPTDSSPSQAITSWPLGSPPKDLISTEPVFSVVPPMTAAE ISTSSQESLYISRALETFAAIPVTTLSSFQATSASVTQFHPTEVSKAEVPAARSTVPSVG LSSVSISFPPEPLALDHLRSEKQQHKEGVQLQLVADAIDLRTVPKVDVKVTEKCMDLSAS AVDVKRQTTASEMYGRQISAVQPSIINLSATSSGVTPISLVTETVTVVTCTATASYTTGT ESLVGLELATAAPLQLTTSKHVEPLYRVPSGQTFPTIREEAPINLSLSTSAHPVTSAPTK SVTAPPVGVTNGWTDSSTSQSITDGEVVDLSTSKTHRTVVTMDEASSNVVTKIIEDDEKP VDLTAGRRAVCCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGG MKPSMSDTNLAEAGHFFYKSKNAFDYSGGTDTAVDLTSGRITTGEVMDYSSKTTGPYPET RQVISGVGISIPQYSTARMTPPPGPQYGVGSVLRSSNGVVYSSVATPVPSTFAITTQPGS IFSTTMRDLSGVHTNDAVTSLSALHQSQPMPRSYFLTTGASETDIEVTGIDISASLQTIT METLTAEKIDSVPTLTTASEVFSEVVGEESALLIIPEEDKQQQQLDLERELLELEKIKQQ RFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLYQQEEERQAQFMMRQETLAQQ QLQLEQIQQLQQQLHQQLEEQKIRQVYQYNYDPSGTASPQSTAEQAILEGQYVAPEGGQF WATEDATTTASAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVIVKEEKQ PKKRSSGAKVRGQYDEMGENLADDPRCFKKIVDSGVQTDDEDSADRSYVSRRRRTKKSVD TSVQTDDEDQDEWDVPARSRRKARVGKYGDSPAEADKAKPPSKVSSIAVQTVAEISVQTE PVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKD KKRPTPLEIGYSSHLRADSTLQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPD DISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTAKGSQ TTATSGTQKKVKRTLPNPPPEETSTGTQSAFSAMGTVSRRRICRTNTMARAKILQDIDRE LDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAE DRDYMSDSEVSSTRPTRIESQHGIERPRTAPQTEFNQFIPPQTQTESQLVPPTSPYTQYQ YSSPALPTQAPTPYTQQSHFQQQTLYHQEVSPYQTQPTFQAVATMSFTPQAQPTPTPQPS YQLPSQMMVIQQKPRQAALYLEPKITSNYEVIRNQPLMIAPVSTDNTYAVSHLGSKYNSL DLRIGLEERSSMASSPISSISADSFYADIDHHTSRNYVLIDDIGEITKGTAALSTAFSLH EKDLSKTDRLLRTTETRRSQEVTDFLAPLQTSSRLHSYVKAEEDPMEDPYELKLLKQQIK QEFRRGAESLDHLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQS KHKKSLIDPKMSKFSPIQETRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNI TDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDS SSSSLRLKAQEAEALDVSFGHASPSGRTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQ PMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAM SDSEAYHLRREETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMDGKTVH YIFPHARIKITRDSKDHTVSGNGLGIRIVGGKEIPGYSGEIGAYIAKILPGGSAEQTGKL VEGMQVLEWNGIPLTSKTYEEVQSIISQQNGEAEICVRLDLNMLSDSENPQHLELHEPPK AVDKAKSPGVDPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPG SPSVSKKKHSSSKPTDAAKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSD PFVKVYLLPGRGQVMVVQNASAEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLKKKTLEV TVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKP SVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHL EDAGAAIAAAEAAVQQLRLQPTKPTNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSAAGE TNLFPIPRIGKMGQNGQEPIKQTGVGIGLADTEVKTQVMGEIKIALKKEMKTDGEQLIVE ILQCRNITYKFKSPDHLPDLYVKLYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLS PAGHSLQILLFSNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH NT seq 15462 nt NT seq  +upstreamnt  +downstreamnt atgggcaacgaggcgagcctggaaggggaagggctccccgaagggttggcggcggcagca gcggcagcagccggaggaggggctggcggggcggggagccccttgcacaccgtgatcccg gccggcatggaagcggatctgagccaactgagcgaagaggagaggagacagatcgctgct gtcatgtcaagggcgcaggggctgcccaaaggaagcgttaccccggccgctgcggagccg ccttccatgcacaggaaacaagagttggatagtagtcaacctccaaagcaaccaggaaaa ccaccagaccctgggcgtccaattcagcctggtctcagtaagagcagaactacagacact ctgaggtcagagcagaaattgcctggaagaagtccttccactattagcttgaaagaatcg aagtccagaactgattttaaggaggagcacaagtctagtatgatgcctggcttcctctca gaggttaaccctttaagtgctgtttcctctgttgtaaataaattcaatccttttgatttg atatcagaccctgatgcctcccaggaagaagcctccaagaaacaaaaaatagctcagaag gaacaaggaaaacctgagggagtcacaaagcctccatcacaacaacagtctcccaagaca gttcctaagcagccaggacctgtgagggctccacttcagcaggaaggttctccaaaatcc ggatcctctcagccaccagaaaaaagtaaatcacaacctccagaaacaggaaagccagct cagggcttcccccaggctcctcagacagaccaggcaaaattgccaattcagagagatgta tctaggcctcagactaaacagacagacccaggaaggggtgagtcagctaaaccctcactg cagagcccctccaagccacctattcagcaaggaagtcctggaaaatctccagcccagcag cctggacctgaaaaacgtaccataccacagcctgggcctgcaaagcctctagctcaacaa ctgggaacagcaaagcccctggcccaagctccaggggcagcgaaatccctggctcaccag cccgggccacagtctccagctcagccgcctgggccagcaaaggctccagctcagcaggtt gggacaacaaagcctcaggcccagttgtctgggccaggcaagactccacctcaacagcct ggcccaacgaaaccccctcctcaacagccgggcccagtgaagccccctcctcaacagcca ggcccagcaaagccctctcctcaacagcctggtccagcgaaaccccctccgcaacagcct ggtccagcaaaaccccctcctcaacagcctggtccagcgaagccccctcctcaacaacct ggtccagtgaagccccctcctcaacagcctggtccagcgaagccgcctcctcaacagcct ggtccagtgaagccccctcctcaacagcctggtccagcgaagccccttcctcaacagcca ggcccaatgaagccccttcctcaaccgccaggttcagcgaaaccccctcctcaactgcca ggcccagcgaagccccctcctcaacagcctggtccagcgaagccccctcctcaactgcca ggtccaacgaagcaccctcctcaacagccaggacctgtaaaaccctcagctcagcaatct acaaaaccagtaagccaaacaggagctggaaaacctctacagccaccaacgtttccatct gcagcacagactccagtacacggcctgcctaaaaccatctgccctctttgcaataccact gaacttctgttgcatgttccagaaaaggccaattttaacacatgcactgagtgtcagacc actgtttgtagcctctgtggttttaatcccaatcctcatttaactgagatgaaagagtgg ctctgtttaaactgtcagatgcagagagctctaggaggtaacctggctccaattccatca tcaccccagcccaaaccgaagactacccctgttcctgcatcagcagtgagcaagccaccc actccgtcacagcaggtttctccaaagaaagatactacacccaaacaggatgtctcaaag gtagctgagtctaaaaagcccccaccgctagtgaaacaaccaacccttcacagtccccac ccagtcacatcccagcagcctcctgaggcagagtcctcatctaagccagtccctcccaaa gagccttctgtctcgtctgaaccggccaaggtctccatggcagatgataaaccagagcag cccaagacaggaaagccagccacagacattgtgtcttcatcatcaacagcaacaagaccg gatattctaggctccaaaataccatcaaaggatcaagagaaaggaactcctcctctaaaa ccagactctgccaaaccttctcagagttttccaccaacaggagaaaaaattagcccagta gattctaaagtcatacctcgacctgcatcagatacaaaaattatttcacatcctggacct actccagagagcaaagatcagaaacaagttgatccaattcagaaaaaggacgaacccaag aaagcacaaaccaaaatgagtcctaagccagacaccaagccgatgccaaaagggtcaccc acaccccaggttccacgaccccccactggacaaactgcccctctatctccacagccccca aagcctcaggagcagtcgagacgttttagcctaaatctgggaagtattactgatgcccct aaatcacagcccacgactcctcaagaaacagtgactgggaaactctttggatttggagca tccatctttagccaggcatcaaatctgatctccacaggaggccagcctgggtctcattca cagggtgggccagcggccccgataaaacaagtccctcctccttcacaaccacctacttct caagggccacccaaatccacagcaccgccagcacctgcaaaggttctacctgtgaaaaag gaaaccaaagctccagtaattgaaaaactagagcccaaagctgaacaagtttcaacagta aaaagaacagaaacagaaaagaagcctctgcctactaaggacagcaaaccgtccacagct gaacctcaaaaggttgttcttccccccaagctggaagaaacccccaaaccagaatcagcc tgtcctctctgcaaaactgaactcaacataagttctaaggatcctgctaacttcaacact tgcactgaatgtaagaaacaagtgtgtaatctctgtggatttaaccctacaccgcacttg actgagattcaagaatggctttgtttaaattgccaaacccagagagcaatatcaggacag ctgggagacatgggcaaaatgccacctacacaggcaggaccaaaagcctctcctatgcct gtccctatggaacaaccatttcaggaaacagcaatgcctgccccagtaaaagtgaaaaag aaggaacaagaagaaaaaccagaagcagaaaaaaccatttcagaaaaggtaaaagaaacg tcttcaggtgaaaaaagtacccctaaggaaaccatagatcaaatccgagaggagagtaaa gacaaaacttcagcccctcaagaaaaaaagtcaccccctgaagacaaaaagccaccttct gaagacaaaaagccactccctgaagaagaaaagccacctcttgaagaaaaaaaaccaatc cttaaagacaaaaagccggctcttgaagacaaaaagttagccccagcaacaaaagcatcg gttttagaggaagaacagaaacgtgacttacttaaaactcaagtacaaattgctgaagta aaatctgaaggcagagtgcctccggaagcagtggaagaaaagaaacaaccgcggatggag atggaagatttaccagccagcgcacctcggcgtttgcctaaagaagatgatgggatgact caaaaaataaaagtacagccacaggcaccatgcgtggcaaagcctgatcagacggaatct ggaaaggaaaaaacagaaaaggaagatgacaaatcagacacttcaagctctcagcagccg aaaagcccacaaggtcttagtgacacaggatattcttctgatggaatatcaagttcactt ggtgaaattccaagtcttattcccagtgacgaaaaggatttgctcaagggactcaaaaag gactccttttcacaagaaagcagcccttccagcccctcagatttggctaagttagaaagt acagtcctatctattttagaagctcaggcaagtacacttgttgaagaaaagtcagaaaag aaaacacagccccatgaggtttctcctgagcagcctaaggaccagcagaaaactcagagt ttagtagaaaaactggaatctacagtttcagaggaggagaccaaagagagtcaagaagaa ggagacacttttaaaaaagagagccaacaagacattccttcccgaaaggaccaagaaaag cctgaatttgttgatgagttggctacaaggagacagccttatgattcaattgaagacagt agtgaaagcgaaaactcacctgttccgccaagaaaagggaggactagtgttggatcatca agcagtgatgagtataaacaggaagacagccaaggatcaggtgaagacgaggacttcatt cgaaagcaaatcatagaaatgagtgctgatgaagatgcttcagattctgaagatgatgag ttcatcaggaaccagctcaaagagattagcagtagcatagaaagccagaggaaggaagaa accagggggaaggggaaaggaacagcagggaaacacaggcgactgacacgaaaaagtagt gcaagctttgatgacgatgcaggaagacggcattcctggcatgatgaagatgatgagacc tttgatgaaagtcctgagcttaaataccgagaaactaaaagtcaggagagtgaagaactt gtagttgccggaggaggaggaggactccgtcgatttaaaacaattgaactcaacagcacg atagccgataaatattctgcagagtcgtcacagaaaaaaacagctttgtattttgatgat gagccagaattagaaatggaaagcctgacagactctccagaagatcgatcaaggggggaa ggatcttctagtcttcatgcttccagcttcactcctggcacatcccctacatccgtttct tctcttgatgaagacagtgatagtagtccaagtcacaaaaagggagagagcaaacaacaa cgcaaagctcgacatagatcacatggccctcttttacctaccattgaagattcttcagag gaagaagaattgagagaggaagaagagttattgaaggagcaagaaaagcaacgggaatta gaacagcagcaaagaaagagttctagtaagaaatcaaagaaagacaaagatgaacttcga gctcagagaaggagggaaagaccaaagacaccacccagtaatctctctcccatcgaagat gcatctccaacagaagaattacgtcaggctgcagaaatggaggagctccatcgatcttcg tgttctgagtattcacctagcatagagtcagacccagaaggctttgaaataagcccagaa aaaataatcgaagtacaaaaagtttataaattgcccacagctgtgtctttatactcaccg acagatgagcaatctattatgcagaaagaaggtggccaaaaggcattaaaaagtgctgag gagatatatgaagaaatgatgcataaaagccagaaatataaagcttttccagctgcaaat gaacgagacgaaatgtttgaaaaagagcctttgtatggtgggatgctaatagaagattat atttatgaatctttagtagaagacacatacaatggttcactcgacagcagtctgctcgca aggcaagaagaagaaaatgggtttttgcagcagacaaggagagagcaaaaaatgagactt ccggaacagatttatgaagatcccatgcagaaaattacagacctccagaaagagttttat gagttagaaaatttacatgctgttttgcctcaagaagacatagtttcaagttcttttatc atcccagaaagtcatgagattgtcgatctgggtagtatggtaacctctaccagtgaagaa aaaaaattattagatgctgatgctgcctatgaagaactcatgaaaagacaacagatgcag ttaacacctggatctagtccaacccagcccctcatcagggacgatctgacagagtccact gtggactttgatagggtacctgatgcgtctttgacatcaagtgttctctcaggagcatct cttacagattcaaccagcagcacaacactctctatcccagacgttaaaataacccagcat ttttcagcagaagaaattgaggatgagtatgtgactgattatacaagagaaattcaagag ataattgctcatgaatcactgattttgacctactctgaaccttcagaaagtgctacatca gtcccaccctctgacacaccgtctctcacatcatctgtttcttcagtttgtaccacagat agctcctcacccattactaccctggatagcatgaccacagtttatactgagccagtggac attgtagctaaatttgaagatgctgaggatatttcttcatcaacatatttcccaggcagc attatagactatccagaagacataaatatacctttagatcagacaaccatacaggatggt agaactggtacagatcacgttgtgatttccttatctggtagagaacctgctcccgtagaa tctgtaggaacgaaactcgaggggctaattgctgacactgtttctactgactcatctata tctgaaaaagatgcagcgaagaaggccagaacggaaacaggggatggacttattctggaa gttttggaagcttatagagatactaggaaggagtctgaggctgaactgacagaaattagc ttacctgacactgtgtttgatcagacaccttcttctgtaaaaactcttccaatgaaggag caggtgtcaacgacatgctttttacctgaagaggttttgggtcaagcaaaacctgcatct cagctaccatctggcactcctcccattttctctcttccaactaaaactcgtccattcctt cgaagttcttctttggacatatcagcccaaccccctccccctcctcctccccctcctccc cctcctccgcctccccctcctcctcctcctcctccaccccttcctccaccaacctcacct aaaccaaccattcaccctaaaaaaaaattagcggttacagctccagtgactgcaactact gcagctacatctctagtagattctgttactacagtggaaaccacatctgctcccagaagt aatgggttacctatgacaaaagtatataccactgcacctcctcctgttcctcctaagcca tctttaattccatctggacttgtatttacacataaacccgagccaagcaaacctccactt gctcctaaaccagcagttcctcagcctccagtcacgaccccaaaactaacagatacatac cccaaaccaacaggtctacctttaactacaagtatgacattaaatttagtgacatcagca gactataaattgccttcccctacctctccactttcccctcactctaacaagtcctcgcca agattttccaagtctcttatggaaacttatgtggttatcacattgccatctgaacctggc actccaacagattcttcacctagtcaagctattaccagttggcctttgggatcacccccc aaagatctgatttccactgaaccagtattttctgtagttcctccaatgacagctgcggaa atatcaacttcttcacaagagagcctgtacatctccagagctttggagacatttgctgct atcccagtcacaacactatcttcatttcaagcaacttcagcttcagttacacagtttcac ccaactgaagtttccaaggctgaggttccagcagcaagaagtacagtccctagtgttggt ctcagcagtgtctctatatcctttcctccagagcctcttgctctagatcacctccgttca gagaagcagcagcataaagaaggtgtccagttgcagcttgttgctgatgccattgatctg cgtacagtacccaaagtagatgttaaagtaactgaaaaatgtatggatctttctgcctct gcagtggatgtgaagaggcagaccacagcaagtgaaatgtatgggagacaaattagtgct gtccaaccctcaattataaatctgagcgcaacttcatcaggagtgactcctatatccctg gttacagagacagtgactgttgttacatgcacagctactgcaagttacaccacaggcaca gaaagcctagtgggtctagaacttgcaacagcagcaccactccagcttactacatcaaag catgtggagccactatacagagtaccaagtggccagacctttcctacaattagggaggaa gcaccaataaacttatctttaagtacttctgcacacccagtgacatcagctcctacgaaa tctgttactgcacctcctgttggtgtcacaaatggatggactgacagctccacatctcag agcatcactgatggggaagtagtggatctcagtacctccaaaactcacagaactgttgta acaatggatgaagcttcttcaaatgtggtgactaaaataatagaagatgatgaaaaacct gttgatctgactgcaggaagaagagccgtgtgctgtgatgtggtttataagttacccttt ggaagaagctgcacagcacagcagcctgcaaccactcttcctgaagatcgttttggttat agggatgatcactatcaatatgatcgatcagggccatatggttatagagggattggggga atgaaaccttccatgtctgacactaatttagcagaggctggacattttttctataaaagt aagaacgcttttgattattctggaggaactgatacagcagtagatcttacttcagggaga attactacaggtgaggtaatggattattcaagcaagactacaggtccatatccagaaact cgacaagtcatttcaggagttgggattagtatcccgcagtattccacagcaagaatgact ccacctccaggaccccagtatggtgtggggagtgttttgaggtcgtctaatggggttgtc tattcttcagtagcaactccagttccttccacgtttgctatcaccacacagcctggctcc atcttcagcaccaccatgagggatttgtctggtgtgcacacaaatgacgctgtgacttcc ttgtccgccctgcaccaaagccagcccatgcctagatcctatttcctaacaactggtgca tctgaaacagacattgaagtcactggtattgatatcagcgccagtttgcagactatcact atggagactctcacagctgagaagatagactcggttcccaccctgaccacagcgtctgaa gtattttctgaagtggtgggagaggaaagtgcgcttttaatcatccccgaggaagataag caacaacagcagctagacttggagcgtgagctcttggaactggaaaagatcaagcaacag cgttttgctgaggagttggagtgggaacggcaggagattcaaaggttccgagaacaggaa aagatcatggttcaaaagaagctggaggagctgcagtcgatgaagcagcacctcctctat cagcaagaagaggagcggcaagcccagttcatgatgaggcaggagacgctagcacagcaa cagctgcagctggaacagatccagcagctgcagcaacagcttcaccagcagctggaggag cagaagattcgccaggtctaccagtataactatgacccttctggaactgcctctccacag agcactgcagagcaggccatcctggaaggtcagtatgttgccccagaaggtggtcagttc tgggcaaccgaagatgcaaccaccacagcctcagctgtggtggcgattgaaataccacag agccagggatggtacacggttcagtctgatggggtgactcagtacattgccccacctggc attctgagtactgtttcagaaatacctctgacagatgtaattgtcaaagaggagaaacag cccaagaagagaagttctggagctaaagtccgtggccagtacgacgagatgggggaaaat ctggcagatgacccccgctgctttaaaaagatagtggacagcggggtacagactgacgat gaagattcagcagatcggagttatgtgagtaggcgaaggagaactaaaaagagtgtcgat acaagtgtccaaacggatgacgaagatcaggatgaatgggacgtgcctgctagatctagg aggaaagctcgcgtagggaaatatggtgacagccctgcagaggcggacaaggccaaaccc ccttccaaagtctccagcatagccgttcaaacagtagcagagatatctgtgcaaactgaa ccagttggaaccataagaacaccttcgatacgggcacgcgtggatgccaaggtagaaata attaaacacatttcagcacctgaaaagacttacaaagggggcagtttaggatgtcaaaca gaagcagattcagacacacaaagtcctcaatatctgagtgccacctctccacccaaagac aagaaacgcccaacacctttagaaattggttattcatctcacctccgagcagattccaca ctacagctggctccttccccacccaaatctccaaaagtcctttattctcccatctcacca ctttcaccaggcaaagccttagaatcagcctttgtaccttatgagaaacccctccctgat gatataagtccacaaaaagtactgcatccagatatggctaaagttcccccagcaagtcct aagacagccaagatgatgcagcgctccatgtctgaccccaagcctctgagtccaacagca gacgaaagttccagggctccttttcagtataccgagggctacacggcaaaaggttctcaa accacagcaacctctggcactcagaaaaaagtgaagagaactctgccaaacccaccacct gaagagacctccacaggaactcagtcagcctttagcgcaatgggcacggtctccaggaga aggatctgccgaaccaatacgatggcccgagccaagattctccaggatatagacagagag cttgatcttgtggagagggaatctgccaagcttaggaagaaacaagcagaacttgatgag gaagaaaaggagattgatgctaagttacggtacctagaaatggggattaacaggaggaaa gaggccttattaaaggagagagaaaagagagagagagcctatctccagggagtagctgag gatcgtgattacatgtccgacagtgaggtcagcagcaccagaccaacccgaattgaaagt cagcatggcatcgagcgaccgagaactgctccccaaactgaattcaaccagtttattcca ccacaaacccaaacagaatctcagctagtccctcctacgagtccttatacgcagtaccaa tactcttcccctgctcttcctactcaagcacccaccccgtacacccagcaatcccacttt cagcaacagactctgtaccatcaggaagtttcaccttatcagactcagccaaccttccaa gctgtggcaacaatgtctttcacacctcaggctcaacctacaccaaccccacaaccttct tatcagttaccatcacagatgatggtgatacagcaaaagccacggcaagctgcattgtat ttggagcccaagataacttcaaactatgaggtgattcgcaaccaacccctgatgatagca cctgtttccactgataatacatatgctgtttcccatctcggtagtaagtacaacagctta gatttgagaataggattggaggaaagaagtagcatggccagcagtccaatatcaagcata tctgcagattctttctatgcagatattgaccatcatacttcacgaaattatgtcttaatt gatgacattggagagattaccaaaggaacagcggctctaagcactgcatttagccttcat gaaaaagatctgtcaaaaacagaccgtcttctccgaaccactgagacacgtaggtctcaa gaagtgacagatttcctagcacctctgcagacttcgtccagattgcatagttacgtgaaa gcagaggaggacccaatggaggatccttatgagttaaagcttctgaaacaacagattaaa caagaattccgtagaggagccgagagcttagatcaccttgctggtctttcccattattac catgccgatactagttacagacattttccaaaatctgagaagtacagcattagtagactc acacttgaaaaacaagcagcaaaacaactaccagctgctatactttatcaaaagcagtca aagcataagaaatcactaattgaccctaaaatgtcaaaattctcacctattcaagaaact agagaccttgaacctgattattcgagctatatgacttcaagcacttcatctattggtggc atttcttccagggcaaggcttcttcaagatgatattacttttggcctcagaaaaaatatt acagaccaacaaaaatttatgggatcatctctgggcacaggactgggcaccttaggaaac accatacgatcagctctgcaggatgaagcagataagccatacagcagtggcagcaggtcc agaccttcttccagaccttcctctgtctatgggctagatttatcaattaaaagagattct tccagctcttctctaagactgaaagctcaagaggctgaagctctagatgtttcctttggt cacgcatcaccttctggaagaactaagcctactagtttgcctattagccaaagtagagga agaataccaattgtggcccagaattctgaagaggaaagtccactcagtcctgttggacag ccaatgggaatggccagggctgctgctggacccctgccaccaatatctgcagacaccagg gaccagtttggatcgagtcactctttgcctgaagttcagcaacacatgagagaagaatca cggactcgaggctacgaccgtgacatagcattcatcatggatgacttccagcatgccatg tcagacagtgaagcctatcacctccgtcgtgaagaaacagattggtttgacaaacccagg gagtctcgtttggaaaatggacatggtctagatcgaaaactgccagaaagattggtccac tctagaccactcagtcaacaccaagagcaaattatacagatggatgggaaaactgttcac tacatctttccacatgcaaggataaaaataaccagagactctaaggatcacacggtttca ggtaacggattaggaattagaattgtgggtggtaaagaaatccctggatatagcggagaa attggagcctatattgccaagattcttcctgggggaagtgcggaacagacagggaaactt gtggaaggcatgcaagtattggagtggaatggaattcctttaacttctaaaacatatgaa gaagtgcagagtatcattagtcagcaaaatggggaagcagaaatatgtgtaagactggac ctcaatatgctgtcagattctgaaaatccccagcacctagaactccacgaaccaccaaaa gctgtggataaagcgaaatccccaggggttgatcccaagcagttggcagcagagctccag aaggtctcactacagcagtcaccactggttctgtcgtctgttgttgaaaagggatctcac gttcattcaggtcctacatcagcaggatccagttccgttcccagtcctgggcagccaggg tcaccctcagtgagcaaaaagaaacacagcagcagcaagcctactgatgcagccaaggtt gtctctcatccaattacgggggaaattcagcttcaaatcaactatgatcttggaaatctc ataatacatattctccaagcaagaaacctagtccctcgagacaacaatggttattcagac ccctttgttaaagtgtaccttcttccagggcgaggtcaagtcatggttgtccagaatgca agtgctgagtacaagagaaggactaaatacgttcagaaaagtcttaatcctgagtggaat caaacggtgatttataaaagtatctccatggaacagctcaagaagaaaacactggaggtg acagtctgggattatgatagattttcttccaatgactttcttggtgaggtactgattgat ttatctagcacatctcaccttgataacacgcctaggtggtatccactcaaagaacagact gaaagcattgatcatggcaagtcccattccagtcagagcagccagcagtccccaaagcca tctgtcatcaaaagccgaagccatggtatcttccctgacccgtccaaggacatgcaggtt cccaccattgagaaatcccatagtagtcccggtagctcgaaatcctcatccgaaggccat ctccgctctcatggaccatctcgcagtcaaagcaaaaccagcgtcactcagacccacctg gaagatgcgggggctgctatagccgctgctgaagccgctgtgcaacaactccgccttcaa ccaaccaagcccaccaatcaccggcctgcagaaagctccgtgtccactggctcctcgggc agcagctttggcagtgggtatagcgtggacagtgaaggaagcagcagcgctgcaggggag actaatctatttcctattccaaggataggaaagatgggacagaatgggcaagagcctata aaacagacaggagtaggcataggactagcagacactgaagttaaaactcaggtaatggga gaaatcaagattgcattgaagaaagaaatgaagacagatggggaacaactaatagttgaa atcctacagtgtagaaatattacctacaaatttaaatctcctgatcacttaccagattta tatgtgaaactatatgtgatgaacatatctacccaaaagaaggtgatcaagaaaaaaaca agagtatgtagacatgatcgagagccttcattcaatgaaactttcagattcagcctaagt cctgctggacattctcttcagattttacttttttccaatggagggaagtttatgaaaaag accttgattggcgaagcctgtatctggctagacaaagtggatctcagaaaaagaatagtc aactggcacaaacttttggtcagtcctactcaaacccactga

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