KEGG   Budorcas taxicolor (takin): 128048807
Entry
128048807         CDS       T08909                                 
Symbol
KMT2D
Name
(RefSeq) histone-lysine N-methyltransferase 2D isoform X1
  KO
K09187  [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
Organism
btax  Budorcas taxicolor (takin)
Pathway
btax00310  Lysine degradation
btax01100  Metabolic pathways
btax04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:btax00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    128048807 (KMT2D)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    128048807 (KMT2D)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:btax03036]
    128048807 (KMT2D)
Enzymes [BR:btax01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     128048807 (KMT2D)
Chromosome and associated proteins [BR:btax03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     128048807 (KMT2D)
   HMT complexes
    MLL-HCF complex
     128048807 (KMT2D)
SSDB
Motif
Pfam: PHD SET FYRC FYRN zf-HC5HC2H zf-HC5HC2H_2 PHDvar_NSD PHD_NSD HMG_box
Other DBs
NCBI-GeneID: 128048807
NCBI-ProteinID: XP_052497199
LinkDB
Position
5:75580500..75620025
AA seq 5619 aa
MDSPKPPGEDKDSEPAADGPAASEESGATEPDLPKPHVGEVSVPSSGGPRLQEPPQDCSG
GPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGNPGPNEGALPSEDLSQIGF
PEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGA
SIPCRSPGCSRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAHLEEARCAVCEGPGELCD
LFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHT
FCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAPGGQPVSS
LAEQHPPVCSRFSPPEPGATPTDEPNSLYIACQGQPKGGYVTSMQPKEPGPLQCEAKPLG
REGAQLEPQLEAPLNEEMPLLPPPEESPLSPPPEDSPTSPPPEASRLSPPPEDSPLSPPP
EESPLSPPPESPPFSCPEDSPSHPPLDTPLPPPPEASPLSPPLEESPLSPPPEELPTSPP
PEASRLSPPPEESPMSPPPEESPMSPPPEASCLFPPFEESPLSPPPEESPLSPPPEASRL
SPPLEDSPMSPPPEDLPMSPPPEVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED
SPTSPPPEDPPASPPPEDLLVSLPLEESPLLPLPEELRLCPRPEEPHLSPQPEKPRLSPA
PQEPRLSPAPQELCLSPASEEPHLSPAPQQPCLSPAPEEPRLSPAPQQLHLSPVPQQPHL
SPAPEEPRLSPAPKELRLSPAPQEPCLSTAPQELHLSLMPEEPHLSLASEELRLSPQPEE
PRLSPQPEEPRLSPRPEEPRLSPRPEEPRLSPRPEEPRLSPRPEEPCLSPRPEEPHLSPQ
PEEPIEEPGLCPASEELPLFLPPREPPLSPVLGEPALSEPGEPPLSPLPEELPLSPSGEP
SLSPQLMPPDPLPPPLSPIITTVAPPALSPLGELEYPFDAKGDSDPESPLAAPILETPIS
PPPEANCTDPEPVPPMILPPSPGSPMGPASPILMEPLPPHCSPLLQHSLPPSNSPPSQCS
PALPLSVPFPLSPMDKAVEVSEEAEPQKMETEKAPEPECPALEPSPTSPLPSPLGNLSCP
APSPAPALDDFCGLGEDTAPLDGTDTPGSQPEAGQTPGSLASELKCSPVLLDSEELAPVT
PMEVYGPECKQAGQGSPCEEQEDPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSE
PLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAIGGGKA
EGDKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRGRGRARLKSTTSSIETLVVADI
DSSPSKEEEDDDDDTMQNTVVLFSNTDKFVLMQDMCVVCGSFGRGAEGHLLACSQCSQCY
HPYCVNSKITKVMLLKGWRCVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTV
PKGGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCGPCASLVTCPICHAPYVEEDLLIQCR
HCERWMHAGCESLFTEDDVEQAADEGFDCVSCQPYVVKPAAPVAPPELVPMKVKEPEPQY
FRFEGVWLTETGMAVLRNLTMSPLHKRRQRRGRPGLPGEAGLEGAEPSEVLGPDDKKDGD
LDTDELLKAEGSVEHMECEIKLEGPVSPDGEPGKEETEESKKRKRKPYRPGIGGFMVRQR
KSHTRVKKGPAAQAEVLSGDGQPDEGETVLPADLPAEGSVDQSLADGDEKKKQQRRGRKK
NKLEDMFPAYLQEAFFGKELLDLSRKALFAVGVGRPSFGLGTPKAKGDGGSERKELPTSQ
KGDDGPDVADEESRGPESKADTPGPEDGGIKASPVPSDPEKPGTPGEGMLSSDLDRIPTE
ELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLDGSRTPLQRPFLQGGLPLGNLPSNSPM
DSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQR
SLQRWEKDEELGQLSTISPVLYANINFPSLKQDYPDWSSRCKQIMKLWRKVPAADKAPYL
QKAKDNRAAHRINKVQKQAESQINKQTKVGDMARKTDRPALHLRIPPQPGALGSPPPAAA
PTIFIGSPTPPAGLSTSADGFLKPPAGTVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAS
AYALEPRFPTVPPTYPPYPSPTGAPAPPPTLGASSRPGTGQPGEFHTTPPGTPRHQPSTP
DPFLKPRCPSLDNLAVPESPGGGGGKAAEPLLSPLPFGESRKALEVKKEELGGSSPSYGP
PNLGFVDSPSSGPHLGGLELKAPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPS
PPSHSDIFRPGPYPDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSS
QSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPSEVAFKA
GPLAHTPLGAGGFPAALPSGPAGELHAKVPSVQPPNFARSPGTSAFVGTPSPMRFTFPQA
VGEPPLKPPVPQPGLPPPHGINSHFGPGPTMGKPQSTNYAVAAGNFRPSGSPLGPSSGPA
GEGYGPSPLRPPSVLPQPAPDGPLPCLPHGAAPRAGITSPVEKREDPGAGTGSSLAAPEL
SGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQMQRNTLRQEKETAAAAGAVGPPGSWGA
EPSSPAFEQLGRGQTPFAGTQDKSSLVGLPPSKLGGPILGPGAFPSDDRLSRPPPPATPS
SMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQQLWQQQQQATAAASMRLTMSARFPST
PGPELGRQTLGSPLAGISNRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGPPFPGQGP
PQRPRFYPVTEDSHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPNLPTG
LELVSRPPSSTELGRPPPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAK
GDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKA
EREALLRGVEPGPLGPEEHPPPAADAPEPRLASGLPEVKPKVEEGGRHPSPCQFTITTPK
AEPAPVTTSLGLGVKPGQSVTGSRDTRMGTGTFSSSGHTAEKVPFGTTGGPPAHLLTPSP
LSGPGGSSLLEKFELESGALTLPGGHASGDELDKMESSLVASELPLLIEDLLEHEKKELQ
KKQQLSAQLQPVQQQQPQQHSLLSTPGPAQAVSLPHEGSSPNLAGPQQQLSLGLGGSRQP
GLAQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQNPQPVLAQKPMG
TMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGS
IGVAPGMNRQQVSLLAQRLSGGPGSDLQNHVAAGSGQERGAGDSSQPRPNPPTFAQGVIN
EADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEK
LKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQHSAVLALSPSQS
PRLLTKLPGQLLPGHGLQPPQGPPGGQAAGLRLTPGGMALPGQPGGPFLNTTLAQQQQQQ
HSGGAGALAGPSGGFFPGNLALRGLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQHLLG
QVAIQQQQQQGPGVQANQALGPKPQGLLPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAV
LQQQQPHPGALGPQGPHRQVLLTQPRVLSSPQMAQQGQGLMGHRLVTSQQQQQHQQQGSM
AGLSHLQQGLMPHNGQPKLGAQPMAALQQQQLQQQQQQQQLQQHQQLQQQQQQQQLQQQQ
QQLQQQQQQQQQLQQQQQQQQLQQQQQQQQLQQQQQLQQQQQQQLQQQQQQLQQQQQQLQ
QQQQQQQLQQQQQQQQLQQQQQMGLLSQSRALLSPQQQQQQQQMTLGPGMPAKPLQHFSS
PGALGPTLILTGKEQSIVETALPSEASEGPSTHQGGPLPMGTVPESVATEPGEVKPSLSG
DSQLLLVQPQAQPQPNSLQLQPPLRLPGQQQPPVNLLHTAGAGSHGQPGSGSSEASSVPH
LLAQSSVSLGEQPGSVTQNLLSSQQPLGLERPMQNNIGPQPAKPGSVPQSGQSLPGAGVM
PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLHALLMQRQLQQSQAARQAPPYPEPGTQPS
PLQGLLGRQPQPGGFPGSQTGPLQELGAGLRPQGPPRLPAPQGALSTGPVLGPVHPTPPP
SSPQEPKRPSSQLPSPSSQLPSEAQLPITQPGTPKPQGPPLELPPGRVSPAAAQLADTFF
GKGLGPWDPPDHLVEAQKLEQSSMAPGHLDQVNGQVVPEPPHLNIKQEPREEPCALGSQA
VKREANGEPVGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGPEGLRAEINGH
IDSKLAGLEQKLQGTPSTKEDTAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEA
LLKQLKQELSLLPLTEPTITANFSLFAPFGSGCPISGQCQLRGAFGSGVLPTGPDYYSQL
LTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDTEGVLRDASE
VKSLDLLAALPTPPHNQTEDVRCRRGRDGDEELRMESDEDSDSPDSIVPASSPESILGEE
APRFPQLGSGRWEQDDRALSPVIPIIPRASIPVFPESKPYGVLDLEATRKLPAPTWEKGK
GSEVSVMLTVSAAAAKNLNGMMVAVAELLSMKIPNSYEVLFPESPARAGIEPKKGEAEGP
GGKEKSLGGKSPEAGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNV
SNLDVRQLSAPPPEEPSPPPSPLAPSPASPPAEPLVELPAEPSAEPPIPSPLPLASSPES
TRPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGGVRQEDEREVAEFMEQLGT
ALRPDKVPRDMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALM
NVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHKI
KGPCEQELSSFAVFRRVYIERDEVKQIASIIQRGERLHMFRVGGLVFHAIGQLLPHQMAD
FHSATALYPVGYEATRIYWSLRTNNRRCCYRCSIGENNGRPEFVIKVMEQGLEDMVFTDA
SPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYL
FRYGRHPLMELPLMINPTGCARSEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSK
QFVHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANR
REKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIIS
SRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN
NT seq 16860 nt   +upstreamnt  +downstreamnt
atggacagcccgaagccgcctggtgaggataaagattcggaaccagcagctgatggacct
gcagcctccgaggagtcaggtgccactgagccagaccttcccaaaccacatgttggggag
gtctctgtgcccagttctgggggtccccggcttcaggagcctccccaggactgcagcggg
ggtccggtgcggcgttgtgctctctgtaactgcggagagcccagtctacatgggcagcgg
gagctacggcgctttgagttgccatttgactggccccggtgtcccgtggtgtcccctggg
gggaacccagggcccaatgagggagcgctgcccagtgaggacctatcacagatcggtttc
cctgagggcctgacacctgcccacctgggagaacctggagggtcctgctgggctcaccat
tggtgcgctgcgtggtcggcaggcgtatgggggcaggagggcccagaactatgtggtgtg
gacaaggccatcttctcagggatctcacagcgctgctcccactgcaccagacttggtgcc
tccatcccttgccgctcgcctggatgttcccgtctttaccacttcccctgtgcaactgcc
agcggttccttcttatccatgaaaacactgcagctgctatgcccagagcacagtgagggg
gccgcacatctggaggaggctcgctgtgcagtatgtgaggggccaggggaattatgtgac
ctgttcttctgtaccagctgtgggcatcactatcatggggcctgtctggacactgctctg
actgcccgcaagcgtgctggctggcagtgccctgaatgcaaagtgtgccaagcttgcagg
aaacctgggaatgactctaagatgttggtctgtgagacgtgtgacaaaggataccatacc
ttctgcctgaaaccaccaatggaggaactgcctgctcactcttggaagtgcaaggcatgc
cgggtgtgccgggcctgtggggcaggctcagctgagctgaatcccaactctgagtggttt
gagaactactcgctctgtcaccgctgtcacaaagccccgggaggacagcctgtcagttct
cttgctgagcagcaccctccggtctgtagcagattctcacccccagagcctggcgctacc
cccactgatgagcccaatagtctgtacattgcgtgccaagggcagccaaagggtggatac
gtgacctctatgcaacccaaggaaccggggcccctgcaatgtgaagccaaaccactaggg
agagaaggggcccaacttgagccccagttggaggcccccctaaatgaggagatgccactg
ctgcccccacctgaggagtcgcccctgtccccaccacctgaggactcacccacgtccccg
ccgcctgaggcatcgcgcctgtccccaccgcctgaggactcacccctctctccaccgcct
gaggagtctcctctgtctcccccacctgagtcaccacccttctcttgcccagaggactcc
ccctcacatcccccacttgatacacccttacccccaccacctgaagcatcacccctgtcc
ccaccactggaggagtctcctctgtcccctccccctgaagaattgcctacttccccacca
ccggaagcatctcgcctgtctccaccaccggaagagtcacccatgtctccgccacctgaa
gagtcacccatgtctccgccacctgaggcctcttgtctgttcccaccgtttgaggagtcg
cccctgtcccctccacctgaggaatctcctctctctccgccacctgaggcgtcacgccta
tccccaccacttgaggactcacccatgtccccaccacctgaagacttgcctatgtccccc
ccgcctgaggtgtcacgcctgtcccccccgcctgaggagtctcccctgtcaccgccacct
gaggagtctcccacatcccctccacctgaggcttcacgcctgtctcctccgcctgaggac
tcccctacatccccgccacctgaagacccgcctgcttccccgcctccggaggacttgctc
gtgtccctgccgctggaggagtcaccgctgttgccactgcctgaggaactgcgactctgc
ccccggcctgaggagccacacctgtcccctcaacctgagaaaccgcgcctgtctcctgca
ccccaggagccgcgtctgtcccctgcaccccaggagctgtgcctgtcccccgcatctgag
gagccacacctgtcccctgcaccccagcagccgtgcctgtcccctgcgcccgaggagcca
cgcctgtcccctgcaccccagcagctgcacctgtcccccgtgccccaacagccacacctg
tcccctgcgcctgaggagccacgcctgtcccccgcgcccaaggagctgcgcctgtcccct
gcaccccaggagccctgcctgtccaccgcgcctcaggagctgcacctgtccctcatgcct
gaggagccacatctgtcccttgcatccgaggaactacgcctgtctccccagcctgaggaa
ccgcgcctgtctccccagcctgaggaaccacgcctgtccccccggcctgaggaaccgcgc
ctgtcccctcggcctgaggaaccgcgcctgtctcctcggcctgaggaaccgcgcctgtcc
cctcggcctgaggagccatgcctgtccccccggcctgaggaaccgcacctgtcccctcaa
cctgaggagcccattgaggagccaggcctgtgccctgcatctgaggaattgcccttattc
ctcccacccagggagccacccttatcccctgtgcttggagagccggccctgtctgagcct
ggggaaccacctctgtcccctctgcctgaggagctgccgttgtccccatctggggagcca
tctttgtcacctcagctgatgccaccagatcctcttcctcctccactttcacccatcatc
acaactgtggccccaccagccctgtctccgttgggagagttagagtacccctttgatgcc
aaaggggacagtgaccctgagtcgccactggctgcccccatcttggagacacctatcagc
cctccaccggaagctaactgcactgaccctgagcctgtaccccctatgatcctcccccca
tccccaggctcccccatgggaccggcctctcccatcctgatggagccccttccccctcat
tgttccccactcctccagcattccctgcctccctcaaactcacctccttcccagtgctct
cctgccttgccactgtcggttcctttcccgctgagtcccatggacaaggcagtggaggtc
tcagaagaggctgagccacagaagatggagactgagaaagccccagaacctgagtgccca
gccttggaacccagccctactagtcctcttccgtctcctctggggaacctttcctgccct
gcacccagccctgccccagccctggatgacttctgtggcctgggggaagatacagcccct
ctggatgggactgacactcctggttcacaaccagaggctggacagacccctggcagtttg
gctagtgaacttaagtgttcccctgtgctcctggactctgaggagctggcccctgtgacc
cctatggaggtctatggcccagaatgcaagcaggcagggcagggctcaccctgtgaagag
caagaggatccacgtgcaccagtggccccgaccccacctactctcatcaaatctgacatc
gttaatgagatctccaatctgagccagggcgatgccagtgccagttttcctggctcagag
cccctgctgggctctccagatcctgaggggggtggctccctgtccatggagttgggggta
tctacagacgttagtccagcccgagatgagggctccctgcggctctgtaccgactcgctg
ccagagactgatgactcgctattgtgtgatgctgggacagctattggaggaggcaaagcc
gagggggacaaggggaggcggcgcagctccccagctcgttcccgcatcaaacagggtcgc
agcagtagtttcccagggagacgccggccacgtggaggagcacatggaggacgtgggaga
ggacgggcccggctaaaatcaactacttcttccattgagactctggtagttgctgatatc
gatagctctcccagcaaggaggaagaagacgatgatgatgataccatgcaaaatactgtg
gttctcttctccaacacagacaaatttgtgctaatgcaggacatgtgtgtggtgtgtggc
agctttggccggggggcagagggccacctccttgcctgttcccagtgctcccagtgctat
cacccgtactgtgtcaacagcaagatcaccaaggtgatgctgctgaagggctggcgttgt
gtggaatgcatcgtgtgcgaggtgtgtggccaggcctcagacccctcccgcctcctgctc
tgtgatgactgtgacattagctaccacacgtactgcctggaccccccactgctcaccgtg
ccgaagggtggctggaagtgcaagtggtgtgtgtcttgtatgcagtgtggggccgcctcc
cctggcttccactgtgaatggcagaatagttacacacactgcgggccctgtgccagcctg
gtgacctgccctatctgtcatgccccctacgtggaggaggacctgctgatccagtgtcgc
cactgtgaacggtggatgcatgccggctgtgagagcctcttcacagaggatgatgtggag
caggcagctgatgagggcttcgactgtgtctcctgccagccttacgtggtcaagcctgct
gcgcctgtcgcacctccagagttggtacctatgaaggtgaaagagcctgagccccagtac
tttcgcttcgagggcgtgtggctgacagaaacgggcatggcggtgctgcgtaacctgacc
atgtcgcctctgcacaagcggcgtcagaggcgtggacggcccggcctcccaggtgaggcg
gggctggagggggccgagccttcagaggtcctgggccctgatgacaagaaggatggtgac
ctggacacggacgagctgctcaaggctgaaggtagtgtggagcacatggagtgtgaaatt
aaactggagggtcctgtcagccctgatggagagcctggcaaagaggagactgaggagagc
aaaaaacgcaaacgcaaaccctatcggcctggcatcggtggtttcatggtgcgacagcgg
aaatcccacacacgtgtgaaaaaagggcctgcagcacaggcggaggtgttgagtggggat
gggcagcccgacgagggtgagacggtgttgcctgctgacctgcctgccgagggctctgtg
gaccagagcttagccgatggggatgagaagaagaagcagcagcggcgagggcgcaagaag
aacaaactggaggacatgttccctgcttacctgcaggaagccttctttgggaaggagctg
ctagacctgagccggaaggccctgtttgcagttggcgtgggccggccaagctttggattg
ggaacccccaaagccaagggcgatggaggctcagagaggaaggagctcccgacctcacag
aaaggagatgatggtccagatgttgcagatgaagaatcccgtggccctgagagcaaggct
gatacaccaggacctgaggatggtggcataaaggcatccccagtgcccagtgaccccgag
aagccaggcaccccgggtgaagggatgcttagctctgacttagacaggattcccacagaa
gaactgcctaagatggaatccaaggacctgcagcagcttttcaaggacgttctgggttcc
gaacgagagcagcatctgggttgcggaacccctggcctggacggcagccggacaccgctg
cagaggccctttcttcaaggtggactccctttgggcaatctcccctccaacagcccaatg
gactcttacccgggcctctgccagtccccattcctggattctagggagcgcgggggcttc
ttcagcccagaacccggtgagccagacagcccctggacaggctcggggggcaccacgccc
tccacccccaccacccccaccacggagggtgagggcgacgggctctcctataatcagcgg
agtcttcagcgctgggagaaggacgaggagttgggccagctctccaccatctcgcctgtg
ctgtacgccaatattaacttccccagtctcaagcaggattacccagactggtcaagccgc
tgcaaacaaatcatgaagctgtggagaaaagttccagctgctgataaagccccctacctg
caaaaggccaaagataaccgggcagctcaccgcatcaacaaggtgcagaagcaggctgag
agccagatcaacaagcagaccaaggtgggcgacatggcccgcaagactgaccgaccggcc
ctacatctccgcattcccccccagccaggggccctgggcagtccgcctcccgctgctgcc
cccaccattttcattggcagccccactccccccgccggcttgtctacctctgcggacggg
ttcctgaagccgccggcgggcacggtgcccggccccgactcgcctggtgagctcttcctc
aagctcccgccccaggtgcccgcccaagtgccttcgcaggacccctttggactggcctct
gcctatgctctggagccccgcttccccacagtaccacccacctaccctccctatcctagt
ccgactggggcccctgcaccgcccccgacgctgggtgcctcgtctcgtcctgggactggc
cagccaggggagttccacactaccccacctggcaccccccgacaccagccctccacgcct
gaccccttcctcaaaccccgctgcccctcgctggacaacctggctgtgcctgagagccca
gggggagggggaggcaaggctgctgagcctctgctgtcgcctctgccttttggggagtct
cggaaggccctggaggtgaagaaggaagagcttgggggatcctctccaagctatgggccc
ccaaacctgggctttgttgactctccctcctcaggcccccacctgggtggcctggagtta
aaggcacctgatgttttcaaagcccccctgacccctcgggcatctcaggtagagccccag
agcccgggcttgggcctaaggccccaggagccaccccctgcccaggctttggccccttct
cctcccagccactcggacatctttcgccctggtccctaccctgacccctacgcccaaccc
ccgctgacccctcggccccagcccccaccacctgagagctgctgtgccctgcctccccgc
tcactgccctctgaccctttctcccgagtgcccgccagtccccagtcccagtccagctcc
cagtccccattaacaccccgtcctctgtctgctgaggctttctgcccatcccctgttacc
cctcgcttccaatcccctgacccttattcccgtccaccctcgcgccctcagtcccgggat
ccatttgccccattgcataagcccccccgcccccagccctctgaagttgccttcaaggct
gggcctctagcccacactccgctgggggctgggggtttcccagcagccctgccctcaggg
ccagcaggtgagctccatgccaaggtcccaagtgtgcaaccccccaattttgcccggtcc
cctgggaccagtgcatttgtgggcaccccttctcccatgcgtttcactttccctcaggcg
gtcggggagcctcccttaaagccccctgtccctcagcctggtctccctccaccccatggg
atcaacagccattttgggcccggccctaccatgggcaagcctcaaagcacaaactacgca
gtagccgcagggaacttccgcccatcgggcagccccctggggcccagcagcgggcctgca
ggagagggctacgggccgtccccgctgcgccccccgtcagtccttccccaacccgcaccc
gacgggcccctcccctgcctgccccatggggccgcaccacgggcgggcatcacctctccg
gtcgagaagcgagaagacccaggggctggcacgggcagctctttggcggcacctgagctt
tcaggtacccaggacccaggcatgtctggcctcagtcagacagaactagagaagcagcga
cagcgccagcgactgcgggagctgttgattcggcagcagatgcagcgcaacacccttcgg
caggagaaggagactgcggcagctgccggagcagtgggacccccaggcagctggggtgct
gagcctagtagccctgcgtttgagcagctgggtcgaggccagaccccctttgctgggacc
caggacaagagcagccttgtggggctgcccccaagcaagctgggtggccccatcctgggg
ccaggggctttccccagtgatgaccgactctcccggccacctccaccagccaccccttcc
tctatggatgttaacagccggcaattggtggggggctcccaagccttctatcagcgagca
ccgtatcctgggtccctgcccttacagcagcagcagcagcagcaactgtggcagcagcag
caacaggcaacagcagcagcttccatgcgacttaccatgtctgcgcgctttccctcaact
cctgggcctgaacttggtcgccaaaccctaggttcccctttggctggaatttccaaccgc
ctgcctggccctggtgaaccagtgcctggcccagctggtcctgcccagttcattgagttg
cggcacaatgtacagaaaggactcggaccgggggggcctccatttcccggtcagggccct
ccacagagaccccgtttttaccctgtaactgaggattcccaccgactggcccctgaaggg
cttcgtggcctagcagtctcaggccttcctccacagaaaccttcagccccaccagctcct
gaactgaacaacagcctccatccaacgccccacaccaagggtcccaacctgcccactggc
ttggagctagtcagccggcccccctccagcactgagcttggccgcccccctcctctggcc
ctggaagctggaaaactaccttgtgaggatcctgagctggatgatgactttgatgcccac
aaggccttggaggacgatgaggagcttgctcacttgggcctgggtgtggatgtggccaag
ggagacgatgagctgggtactctggaaaacctagagaccaatgatccccacctcgatgac
ctgctcaatggggatgagtttgacctgctggcctatactgaccctgagctggacacgggg
gacaagaaggacatcttcaatgagcatctgaggctggtggagtcagccaatgaaaaggct
gaacgagaggctctgttgcgaggggtggagccaggacccttgggccccgaggagcaccct
cccccggctgcggatgcgcctgagccccgtctggcatcagggcttcccgaggtgaagccc
aaggtggaggagggtgggcgccacccttccccttgccagtttaccattaccacccccaag
gcagagccagcacctgtcaccacttccctaggcctgggggtgaagccaggtcagagtgtg
acgggcagccgggacactcgaatgggcacaggaactttttctagcagtgggcacacagct
gagaaggtcccctttgggaccacaggaggaccaccagctcacctgctgacgcccagccca
ctgagtggcccgggagggtcctccctactggaaaagtttgagctagagagtggggccctg
actttgcctggtggacatgcatctggggatgagctggacaagatggagagctcactggta
gccagtgagttacccctgctcattgaggacctgttggaacatgagaagaaagagctgcag
aagaagcagcagctttcagcgcagctgcagcctgtgcagcagcagcagccccagcagcat
tccctgctgtccacgccaggccctgcccaggctgtgtctttgccccatgagggctcttct
cccaatttggctggccctcaacagcagctttccctgggacttggaggctcccgacagcca
ggcttggcccaaccgttgatgcccacccagccaccagctcatgccctccagcagcgcctg
gccccatccatggccatggtatccaaccaagggcatatgctaagtgggcagcatggggga
caggcaggcttggtgccccagcagaacccacagccagtgctggcacagaagcccatgggt
accatgccaccgtccatgtgcatgaaaccacagcagctggcaatgcagcagcagttggct
aacagctttttcccagatacagacctggacaaattcgctgcagaagatatcattgatcct
attgcaaaggccaagatggtggctttgaaaggcatcaagaaggtgatggctcagggcagc
attggagtggcacctggtatgaacaggcagcaagtgtccctgctagctcagaggctctca
ggggggcccggtagtgatctgcagaaccacgtggcagctgggagtggccaggagcggggt
gccggtgactcctcccagcctcgtcccaatccacccacttttgcccagggagtgatcaat
gaggctgaccagcggcagtatgaggagtggctgttccatacccagcagctcctacaaatg
caactgaaggtgctagaggagcagataggggtgcaccgcaagtcccggaaagccctgtgt
gccaagcagcgcactgccaagaaggctggccgggagttccccgaggctgatgctgagaag
ctaaagctggttacagaacaacagagcaagatccagaaacagctggatcaggtccggaag
cagcagaaggagcacactaacttaatggcagaatatcggaataagcagcagcagcagcaa
caacagcagcagcaacagcagcagcactcagccgtacttgcccttagcccttcccagagt
ccccggctactcaccaagcttcctggtcagctactcccaggccatgggctgcagccacct
caaggaccccctggggggcaagctgcaggtcttcgcctgacccccgggggcatggcccta
cctggacagcctggtggccccttcctcaacaccaccctggcccaacagcagcagcagcaa
cattctggtggagctggggccctggctggcccctcggggggctttttccctggcaacctt
gctcttcgaggcctgggacctgactcgaggcttttacaggaaaggcagctgcagctccaa
cagcagcgcatgcagctggcccagaaactgcaacagcagcagcagcagcatctcctagga
caggtggcaatccagcagcaacagcagcagggtccaggagtacaggcaaaccaggctctg
ggtcccaagccccagggccttctgcctcccagcagccaccagggcctcttggtccagcag
ctgtccccccaaccaccccaggggccccagggcatgctgggccctgcccaggtggcagta
ttgcagcagcagcaaccacaccctggagctttgggcccccagggccctcacagacaggtg
ctcctgacccagccgcgggtgctaagttctccccagatggcacagcagggtcagggccta
atgggacaccggctggtcacatcccagcagcagcaacagcaccaacagcaaggatccatg
gccgggctttcccatcttcagcagggtctgatgccacacaatgggcagcccaaactgggt
gctcagcccatggccgccttgcagcagcaacagttgcaacagcagcagcagcagcagcaa
cttcaacaacaccaacagcttcaacaacagcagcagcaacagcagctacaacaacagcag
cagcagttacaacagcagcagcagcagcaacagcagctacaacaacagcagcagcaacag
cagcttcaacagcaacagcagcaacagcagcttcagcagcagcagcagcttcagcagcag
cagcaacagcagcttcaacagcagcagcagcagcttcaacagcagcagcagcagcttcaa
cagcagcagcagcaacagcagcttcaacagcagcagcagcaacagcagcttcaacagcag
cagcagatgggcctcttgagccagagtcgagctttactgtctcctcaacagcaacagcag
cagcaacagatgacacttggccctggcatgccagccaagcctctgcaacacttttctagc
cccggagccctgggcccaaccctcatcctaacgggcaaggaacaaagcatcgtagagaca
gctcttccttcagaggccagtgaggggccctccacacatcagggagggcccttaccaatg
gggactgtaccagagtccgtggccactgaaccaggagaggtgaagccctcactgtctggg
gactcacaactcctgcttgtccagccccaggcgcagcctcagcccaattctctgcagctg
cagccacctctgaggctcccaggacaacagcagccgccagttaacttgctccacacagca
ggcgcaggaagccatgggcaaccaggcagtggatcgtctgaggcctcgtctgtgccccac
ctactggcccaatcctctgtttccttaggggaacagcctggatccgtaacccagaacctt
ctgagctcccaacagccccttggactagagcggcctatgcaaaataacatagggccacag
cctgccaagccgggatctgtcccgcagtctggccagagcctgccaggggctggggtcatg
cctacagtgggtcagcttcgggcacagctccaaggagtcctggccaaaaacccacagctg
cggcatttgagtcctcagcagcagcagcagctccacgcgcttctcatgcagaggcagcta
cagcagagtcaggcagcacgccaggccccaccctacccggagcctgggacccagccctct
cccctccaaggcctcctgggccgccagccccaacctgggggcttccctggatcccagaca
ggccctcttcaggagctaggggccgggcttcgacctcagggcccaccccgactccccgcc
ccacaaggagccttatccacaggaccagttcttggccctgtccatcccacacctccacca
tccagcccccaagagccaaagagaccttcctcccaattaccttcccctagctcccagctc
ccctccgaggcccagctccctatcacccagccaggaacccccaagccccaggggccaccc
ttggagcttcctcctgggagggtctcacctgctgctgcccagcttgcggataccttcttt
ggcaagggactgggaccttgggaccccccagaccacctagtggaagcccagaagctggag
caaagcagcatggcacctgggcatctggaccaggtgaatgggcaggtggtacctgagcca
ccacatctcaacatcaagcaggagcctcgggaagagccgtgtgccctggggtcccaggcg
gtgaagagggaggccaacggggagcctgtaggggcaccaggtaccagcaaccacctcctg
ctggcagggccccgctcagaagccgggcatctgctcttgcagaagcttctacgagcaaag
aatgtgcaactcagtactgggcgggggcccgaggggctgcgagctgagatcaacgggcac
attgacagcaagcttgctgggctggagcagaaactgcagggtacccccagcaccaaggag
gatacagcagcaaggaagcctttgacaccgaagcccaagcgggtacagaaggcaagcgac
aggttggtgagctcccgaaagaagctgcggaaggaggacggggtcagggccagcgaggcc
ttgctgaaacagctgaaacaggagctgtccctgctgcccctcacggagcctaccatcacc
gccaactttagcctctttgctccctttggcagcggctgcccgatcagtgggcagtgccag
ctgagaggggccttcggaagtggggtgctgcccacgggccctgactactattcccagctg
cttaccaagaataacctgagtaacccgccgacaccaccctcgtcgctgccccccacccca
cccccatcggtgcagcagaagatggttaatggcgtcactccgtctgaagagctgggggag
caccccaaggatgccgcctctgcccgggacactgaaggggtgctgagggatgcttcagaa
gtgaaaagtctagacctgctggccgctttgcctacgccccctcacaatcagactgaggat
gtcaggtgcagaaggggcagagatggggatgaggaattgaggatggagagtgatgaggac
agcgattctcctgacagcatcgtgccagcttcatcccctgagagcatcctgggggaggag
gccccccgtttccctcagctgggctcaggccggtgggagcaggatgaccgggctctctcc
cccgtcatccccatcattcctcgggccagcattccagtcttcccagagagcaaaccttat
ggggtcctggatctggaggccaccaggaagctgcctgccccaacttgggaaaagggcaaa
ggaagcgaggtgtcagtcatgctgacggtttctgctgctgccgccaagaacctgaatggc
atgatggtggcagtggcagagctgctgagcatgaagatccccaattcctatgaggtgctg
ttcccagagagccctgcccgggccggcatcgagcctaagaagggggaggctgagggccct
ggtgggaaagaaaagagtctgggaggcaagagcccagaggctggccctgattggctgaag
cagtttgatgctgtgttgcctggctatacactcaagagtcagttagacatcttgagtctc
ctcaaacaggagagccctgccccagagccccccacccagcacagctacacctacaacgtc
tccaacctggatgtgcgacagctctcggccccacctcctgaagaaccctccccaccccct
tcccctctggcaccctctcctgccagcccccctgctgaacccttggttgaacttccagct
gaaccctcagctgagccaccgatcccctcgcctctgccactggcctcgtcccctgaatct
acccggcccaagccccgagcccggcctcctgaggaaggtgaagattcccggccccctcgc
ctcaagaagtggaagggggtgcgctggaagcggctccggctgctgctgactatccagaag
ggtggtgtgcggcaggaggatgagcgggaagtggctgagttcatggaacagctcggcaca
gccttgcgacctgacaaggtgcctcgagacatgcggcgctgctgcttctgtcatgaggag
ggggatggggccacggatgggcctgcccgcctgctgaacctggacttggacttgtgggtg
cacctcaactgtgccctgtggtccacagaggtatatgagacccagggcggggcgctgatg
aacgtggaggttgccctgcaccgaggcctgctcaccaagtgctccctgtgccagcgcacc
ggtgccaccagcagctgcaatcgaatgcgttgccccaatgtctaccattttgcctgcgcc
atccgcgccaagtgcatgttcttcaaggacaagaccatgctgtgtccaatgcataagatc
aaagggccctgtgagcaggagctgagctcttttgctgtcttccggagggtctacatcgag
cgggatgaggtgaagcagattgccagcatcatccagcggggagagcggctgcacatgttc
cgggtgggcggccttgtgttccacgccattggacagctgctgccccaccagatggccgac
ttccacagtgccactgccctctatccagtgggctacgaggccacgcgcatctactggagc
ctccgcactaacaaccgtcgctgctgctaccgctgctccatcggcgagaacaatgggcgg
ccggagttcgtgatcaaagtcatggagcagggcctggaggacatggtcttcacggacgcc
tctccccaggccgtttggaatcgcatcattgagcctgtggcagccatgaggaaagaggcc
gacatgctgcgtctcttccccgagtacctgaaaggcgaggagctctttgggctgacagtg
cacgccgtgctgcgcatagctgaatcactgcctggagtggaaagctgtcaaaattattta
ttccgctatggacgccaccccctgatggagctaccactcatgatcaaccccactggctgt
gctcggtcagagcctaaaatcctcacacactacaaacggccccacactctgaacagcacc
agcatgtccaaggcatatcagagcaccttcacaggcgagaccaacaccccgtacagcaag
cagtttgtgcactccaagtcatctcagtaccggcggctgcgcactgagtggaagaacaat
gtctacctggctcgctcccgtatccagggcctgggtctctatgcagccaaggacctagaa
aagcacacaatggtcatcgagtacattggcaccatcattcgcaatgaagtggccaaccgg
cgggagaaaatctatgaggagcagaatcgaggcatctacatgtttcgaataaacaacgaa
catgtcattgatgctacgttgaccggaggccccgccaggtacattaaccattcttgtgcc
cctaactgtgtggcggaagtcgtgacatttgacaaggaggacaaaatcatcatcatctcc
agccggcgaatccccaaaggagaggagctgacatatgactatcagtttgattttgaggac
gatcagcacaagatcccctgccactgtggagcctggaattgtcggaaatggatgaactaa

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