Budorcas taxicolor (takin): 128050783
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Entry
128050783 CDS
T08909
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
btax
Budorcas taxicolor (takin)
Pathway
btax00310
Lysine degradation
btax01100
Metabolic pathways
btax05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
btax00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
128050783 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
128050783 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
btax03036
]
128050783 (DOT1L)
Enzymes [BR:
btax01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
128050783 (DOT1L)
Chromosome and associated proteins [BR:
btax03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
128050783 (DOT1L)
HMT complexes
Dot1-containing complex
128050783 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
128050783
NCBI-ProteinID:
XP_052499124
LinkDB
All DBs
Position
7:21324678..21375348
Genome browser
AA seq
1714 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVVFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSSTATPTKVP
ESKAAVPADTPVDSGAEEEKAGPAAVKKPSPSKARKKKLNKKGRKMVGRKRGRPKKMSAT
NPERKPKKTQSALDLLHAQTVSRAASPLPQDAHRPPHSPFYQLPPSVQRPTPEQLLLAPT
PPALHRLLESFRIQYLQFLAYTKTPQYKATLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EESKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGNRELRSQSLRLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDEALALQLRGKPEAEPGRLHLELDCARFSLPPFSSLSPELSMNGHAAGYELCSAL
GRPSPKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKLVLRRHLS
QDHAASGKAAASELHPRAEHAKENGLPYQSPGITNGIKLSPQDPRPSSPTALQMGEKGPE
KGVKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKARSTPSPGPPA
RESSSTLEKQVAANTHGAGGNTAGSKSLALAPTGFAYSGSVAISGALAGSPAPLGPGAEP
PALDESSSSGSLFATVGSCSSTPQHPPLLTQPRTCGSASPAPQLCASPRLGALGPLPDSG
KGDLPCDASFSDPESEAKRRIVFTISAGASSAKQSPSSKHSPLPSGARGDGGQGHGPDSR
KRGRRKRASAGTPSLSSSVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAIS
SPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEPGSARIERKI
ATISLESKSPPKTLENAGGSLAGRKAPLASEPVNSSKWKSTFSPISDLGLAKAADSPLQA
ASALSHNSLFAFRPGLEEPSTADGKLATHSRKSFPGTLPGAGGLSPNSLPASGFALGGGL
AADLSLHSFSDGASLSHKAPEAAGLGAPLSFPGPRGKEGGAAESGPFANKRQLDGLGPKG
EGGLPTCGPLDKASTAHSKAGKGREREPDVKNGHNLFMAAAAAPPAGLLSGPGLAPAASS
AGGTAPSVQTHRPFLGAFAPGPQFALGPMSLQANLGPSVLQSLFSSVPAAGLVHVSTAAT
RLTNSHAMGSFSSGVAGGAVGGVFNHAVPPASAHPFGASFGSGAACRSTTLSLTPLQAVA
STPASSSQAPSSAEPRPPQPPPHLGRPPPGQPALHAPPHPNATLPPPPALLPANSEPVLL
QNLASLPANQAFLPAASAASLPPANASLSIKLASLPHKVSRPALTVHHQPLPGLALAQAA
PVNPQASSTGPPAVWVSLGMPPPYAARLAGVKPR
NT seq
5145 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atcagatgggtctgtgaggaaatcccggatctcaagctcgctatggagaattacgtttta
attgactacgataccaaaagctttgagagtatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggcaccacacagcccatgaagctgaacaca
cggccgtccactgggctcctgcggcacatcctgcagcaggtctacaaccactcggtgacc
gaccctgagaagctcaacaactatgagcccttctccccagaggtgtatggggagacctcc
ttcgacctggtcgcccagatgatcgatgagatcaagatgaccgaagatgacctgttcgtg
gacctgggcagtggggtgggccaggtcgtgctgcaggttgccgcagccaccaactgcaaa
catcattatggtgtagagaaagctgacatcccagccaagtacgcggagacgatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggagagg
ggggacttcctctcagaggagtggagagaacggattgctaacacaagtgttgtatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaagccctttgcgcctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctgtcgccgctaaaa
ggctcggtgtcatggacggggaagccagtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctaaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgggagaacaagagcagcacagccacacccaccaaggtgccc
gagagcaaggcagctgtgccggcagacacccccgtggactccggtgctgaggaggagaaa
gctgggccggccgctgtcaagaagccatctccctccaaggcccggaagaagaagctgaac
aagaagggccggaagatggtcggtcggaagcgtgggcgccccaagaagatgagtgccacc
aaccccgagcgcaagcccaagaagacccagagcgccctggacctgctgcacgcccagacc
gtgtcacgagcggcctcccccttgccgcaggacgcgcacaggccacctcacagcccattc
taccagctacctcccagcgtgcagcggcctacccctgagcagctgctgctggcacccacc
ccgcccgcgctgcacaggctgctagagtccttcaggattcagtatctacagttcctggca
tacacgaagacccctcagtacaaggccaccctgcagcagctgctggaccaggagaaggag
aagaatgcccggttgctaggcgcagcgcagcagctgtttggccactgccaagctcagaag
gaggagagcaagaggctcttccagcagaaactggacgagctgggagtgaaggcgctgacc
tacaacgacctgatccaagcgcagaaggagatctcggctcacaaccagcagttgagggaa
cagacggagcagctagagaagggcaaccgggagctgaggagccagagcctgcggctgctc
aaggcacggtgtgaggagctgaagctggactggtccacgctgtccctggagaatctgctg
aaggagaagcaggccctgaagagccagatctcagagaagcagaggcactgcctggaactg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagttgctccagctcaag
tcctgcgtgccgcctgatgaggcactggccctgcagcttcgtgggaagccagaggccgag
cctggccggcttcacttggagctggactgcgcccgcttctccctgccgcccttcagcagc
ttgagccccgagctctccatgaatggccatgcggccggctatgagctctgcagcgcactg
ggtcggccctcacccaagcagaacaccccccagtacctggcctctccgctagaccaggag
gtcgtgccctgcacccctagccacagcggccggccacggctggagaagctatccggcctg
gccctgcctgactataccaggctatcccctgccaagctggtgctgcggcgccacctgagc
caggaccatgcggccagtggcaaggcagctgccagcgagctgcacccacgagccgagcat
gccaaggagaacgggctcccttaccagagccctggcatcaccaacggcatcaagctgagc
ccacaagacccccgaccttcatcccccacggctttacagatgggagagaagggccctgag
aagggtgtgaaggagcgtgcctacgccagcagtggggaggccatcaccagcctgcccgtc
agcatcccgctgagcaccgtgcagcccagcaagctgcccgtcagcatccccctggccagc
gtggtgctgcccagccgcgccgagaaggcgagaagcacacccagccctgggccaccggcc
cgagagtcctcgtctacgctggagaagcaggtggctgctaacacccatggtgccgggggc
aacactgctgggagcaagagcctcgccctggctcccacaggctttgcatacagcggctcg
gtggccatcagtggggccctggcaggcagcccagcaccccttggccctggagctgagccc
ccggccctggacgagtcctccagctctggaagcctctttgccactgtggggtcctgcagc
tccaccccgcagcacccacccctgctgacgcagccacgcacctgcggctcagcctcgccg
gccccccagctctgtgccagcccccggctaggcgccctgggcccgctccccgactctggc
aaaggggacctgccctgcgatgccagcttctcagaccctgagagcgaagccaaaaggagg
atcgtcttcaccatctcggcgggtgccagcagcgccaagcagtcaccttccagcaaacac
agccctctgccctcgggtgcccgcggggatggtggccagggccatgggccagacagccgc
aagcggggccggaggaagcgggcatcggcggggacccccagcctgagctcgagtgtgtcc
cccaagcgccgggccttgccatctgttgctgggcttttcacgcagtcttcagggtccccc
ctgaatctcaactccatggtcagcaacatcaaccagcccctggagatcacggccatctcg
tcccctgagagctccctaaagagctcacccgtcccctaccaggacaatgaccaaccacct
gtgctcaagaaggagaagcccctgagccagaccaatggtgcccactactccccactgacc
tcggacgaggagccaggctctgaggatgagcccggcagtgccagaattgagagaaaaatt
gcaacaatctccttagaaagcaagtctccaccaaaaaccttggaaaatgcaggtggcagc
ctagcaggaaggaaggcaccgctggccagcgagccagtcaacagcagcaagtggaagtcc
accttctcacccatctccgacctgggcctggccaaggcagctgacagcccgctgcaggct
gcctccgctctgagccacaactccctgttcgctttccggcccggcctggaggagcccagt
acagccgatggcaagctggccacccactccaggaagagcttcccaggcaccctgccgggg
gcgggcgggctgagccccaatagccttcctgccagtggcttcgccctgggcgggggccta
gcagctgacctcagtttacacagcttcagtgatggtgcttctctctcccacaaggccccc
gaggcagctggcctgggtgcccccctgagcttccccggcccacggggcaaggagggtggc
gctgcagagtctggccccttcgcgaacaagcggcagctggacggactgggcccaaaaggc
gaggggggccttcccacatgcggacccctggacaaggcctccacagcgcacagcaaggca
ggcaagggccgtgagcgcgagcccgatgtcaagaacggccacaacctgttcatggctgcc
gccgccgcgccccctgcaggcctcctcagcggcccaggtcttgccccagcggcatcctcg
gcaggtggcacagccccgtccgtgcagacccaccgccccttcctgggcgccttcgcccct
gggccacagttcgcgctgggccccatgtcgctacaggccaacctgggcccgtctgtgctg
cagtccctgttcagttctgtgcccgccgccggcctggttcacgtctcgaccgccgccacc
agattgaccaactcgcacgccatgggcagcttctcctccggggtggccggcggcgcagtt
ggaggtgtctttaaccacgcggtgcctcccgcctccgcccacccgtttggagccagtttc
ggcagtggggctgcatgtcgcagcaccacgctgagcttaaccccgctgcaggcggtggcc
agcaccccggcctcttcctctcaggccccgtcctctgcggagccgaggccaccccaaccc
cctccgcacctgggccggccccctccggggcagcctgccctccacgcacccccccatcct
aacgccaccttgcctcctccccctgcgctgctcccagctaactctgagcccgtgcttctg
cagaacctcgcatccctccctgctaaccaagctttcttgcccgccgcctctgccgcctct
ctgccgcctgctaacgcctctctgtccatcaagctcgcctccctcccgcacaaggtgtcc
cggcccgccttgacggtgcaccaccagcccctgcctgggttggccctggcccaggccgcg
cccgtgaacccacaggccagctccacggggccgcccgccgtgtgggtttcccttggcatg
ccgcctccgtatgccgcgcgccttgcgggggttaagccgcgataa
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