KEGG   Budorcas taxicolor (takin): 128055367
Entry
128055367         CDS       T08909                                 
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
  KO
K09490  endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
Organism
btax  Budorcas taxicolor (takin)
Pathway
btax03060  Protein export
btax04141  Protein processing in endoplasmic reticulum
btax04612  Antigen processing and presentation
btax04918  Thyroid hormone synthesis
btax05012  Parkinson disease
btax05014  Amyotrophic lateral sclerosis
btax05020  Prion disease
btax05022  Pathways of neurodegeneration - multiple diseases
btax05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:btax00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    128055367 (HSPA5)
   04141 Protein processing in endoplasmic reticulum
    128055367 (HSPA5)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    128055367 (HSPA5)
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    128055367 (HSPA5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    128055367 (HSPA5)
   05014 Amyotrophic lateral sclerosis
    128055367 (HSPA5)
   05020 Prion disease
    128055367 (HSPA5)
   05022 Pathways of neurodegeneration - multiple diseases
    128055367 (HSPA5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    128055367 (HSPA5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:btax03110]
    128055367 (HSPA5)
   04131 Membrane trafficking [BR:btax04131]
    128055367 (HSPA5)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:btax04147]
    128055367 (HSPA5)
Enzymes [BR:btax01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.10  non-chaperonin molecular chaperone ATPase
     128055367 (HSPA5)
Chaperones and folding catalysts [BR:btax03110]
 Heat shock proteins
  HSP70 / DNAK
   128055367 (HSPA5)
Membrane trafficking [BR:btax04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    128055367 (HSPA5)
 Autophagy
  ER-phagy
   ER stress-related proteins
    128055367 (HSPA5)
Exosome [BR:btax04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   128055367 (HSPA5)
  Exosomal proteins of other body fluids (saliva and urine)
   128055367 (HSPA5)
  Exosomal proteins of colorectal cancer cells
   128055367 (HSPA5)
SSDB
Motif
Pfam: HSP70 MreB_Mbl Hydantoinase_A FtsA DDR FGGY_C ParM_N
Other DBs
NCBI-GeneID: 128055367
NCBI-ProteinID: XP_052503862
LinkDB
Position
11:complement(155321220..155325522)
AA seq 655 aa
MKLSLVAAVLLLLLGTARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTNEEEAEDKDEL
NT seq 1968 nt   +upstreamnt  +downstreamnt
atgaagctgtccctggtggccgcggtgctgctgctgctgctcggcacggcacgggcggag
gaggaggacaagaaggaggacgtgggcacggtggtcggcatcgacctgggtaccacctac
tcctgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaac
cgcatcacgccgtcttatgtggctttcactcctgaaggggagcgtctgatcggcgatgca
gccaagaaccagctcacctccaatcctgagaacacagtcttcgacgccaagcgactcatc
ggccggacttggaacgacccgtccgtgcagcaggacatcaagttcttgcctttcaaggtg
gttgaaaagaaaactaaaccatacattcaagttgatgttggaggtgggcaaacaaagaca
tttgctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggct
tatttgggaaagaaggttactcatgcagttgttactgtaccagcatatttcaatgatgcc
caacgccaggcaaccaaagatgctggaactattgctggattgaatgtcatgaggatcatc
aatgagccgacagcagctgctattgcttatggcctggataagagggaaggggagaagaac
atcctggtgtttgacctgggtggtggaacctttgatgtgtctcttctcaccattgataat
ggtgtctttgaagtcgtggccactaatggagatactcatctgggtggagaagactttgac
cagcgtgtcatggaacacttcatcaagctctacaaaaagaagactggcaaagatgttcgg
aaggacaacagagctgtgcagaaactccggcgtgaggtagaaaaggccaaacgggccctg
tcttcccaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttctcg
gagaccctgactcgggccaaatttgaagagctaaacatggacctgttccgttcaaccatg
aagcctgtccagaaagtgttagaagattctgatttaaagaagtctgatattgatgaaatt
gttcttgttggtggctctactcgaatcccaaagattcaacagctggttaaagagtttttc
aatggcaaggagccatcccgtggcataaacccagatgaggctgtggcatatggtgccgct
gtccaggctggtgtgctctctggtgatcaagatacaggtgacctggtactgcttgatgta
tgtcccctgacgcttggtattgaaactgtgggaggtgtcatgaccaaactgattccaagg
aacactgtggtgcccaccaagaagtctcagatcttttctacagcctctgataatcaacca
actgttaccatcaaggtctatgaaggtgaacgacctctgacgaaagacaatcaccttctg
ggaactttcgatctgactggaattcctcctgcaccccgtggggtcccacagattgaagtc
acctttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggc
aacaaaaataagatcacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaa
agaatggtcaatgatgctgagaagtttgctgaagaagacaaaaagctcaaggagcgcatt
gacacaagaaatgaattggaaagctatgcctactctcttaagaatcagattggagataaa
gaaaaactgggaggtaaactttcctcagaagataaggagaccatggaaaaagctgtagaa
gaaaagattgagtggctggaaagtcaccaagatgctgacattgaagatttcaaagcgaaa
aagaaggagctagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggc
cctcccccaaccaatgaggaggaagcagaagacaaagatgagttgtag

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