Budorcas taxicolor (takin): 128055723
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Entry
128055723 CDS
T08909
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
btax
Budorcas taxicolor (takin)
Pathway
btax00270
Cysteine and methionine metabolism
btax00480
Glutathione metabolism
btax01100
Metabolic pathways
btax01240
Biosynthesis of cofactors
btax04216
Ferroptosis
Module
btax_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
btax00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
128055723 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
128055723 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
128055723 (GCLC)
Enzymes [BR:
btax01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
128055723 (GCLC)
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
128055723
NCBI-ProteinID:
XP_052504225
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Position
11:complement(52432954..52477695)
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AA seq
638 aa
AA seq
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MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
EKKKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPSPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPAPFIETFPEDEEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTKDKEIYEQLLQ
EGLDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QELFYFRKDICKAGGNAVVDGCGKAAGRAEPAAEEYALMSIDTIINGKEGVFPGLIPVLN
SYLESMEVDVDTRCSILNYLRLIKKRASGELMTVAKWMREFIAKHPDYKQDSVITDQMNY
SLLLKCNQIANESCECPELLGPAFRKVRYSGSKSDSST
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgcagtcaaggaccgg
cacaaggacgtgctcaagtggggcgatgaggtggagtacatgttggtatcttttgatcat
gaaaagaaaaaagcccaactggtcctgtctggagaggaacttcttgaaactctgcaagaa
aagggggaaaggacgaacccaaaccatccgaccctttggagaccagaatatgggagctac
atgatcgaggggacacccgggcagccgtatggtgggaccatgtctgaattcaacacggtt
gaggacaacatgaggaaacggcgcaaagaggccacatctctcctgggggaaaaccaggcc
ctctgcaccatcacttcctttcccagattaggctgccctgggttcacgctgcctgagttc
aaacccagcccggtggaaggaggagcttccaagtccctcttctttcccgatgaagccatc
aacaagcacccgcgcttcagcacactcaccaggaacatccggcaccggaggggcgagaaa
gtggtcatcaacgtgcccatctttaaggacaagaacaccccagctccatttatagagact
ttccctgaggacgaggaggccgcgaaggcctctaagcccgaccacatttacatggacgcc
atgggcttcgggatgggcaactgctgcctgcaggtaactttccaagcctgcagcatatct
gaggccagatacctttatgatcagttggctaccatctgcccaattgtcatggctttgagc
gctgcgtcgcctttttaccgaggctatgtgtcagacattgattgtcgctggggcgtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaac
cactataggatcagtaagtcccgatacgattcgatagacagttacttatctgagtgcggt
gagaaatacaatgacattgacctgacaaaagacaaagaaatctatgaacagctgttgcag
gaaggcctcgaccacctgctggcccagcacgtggctcatctcttcatcagagacccgctg
actctgtttgaagagaaaatccacctggatgatgccaacgagtccgaccactttgagaat
attcagtccacaaattggcagacaatgcgattcaagcctccacctccaaactctgacatt
gggtggagagtggaattccggcccatggaggttcagctgacggacttcgagaactccgca
tatgtggtgttcgtggtgctgctcaccagggtgatcctgtcctacaaactggactttctc
atcccgctgtccaaggttgatgagaacatgaaggttgcccagaagcgagatgccgtcctg
caggaactgttttatttcagaaaagacatttgcaaagcaggtggcaatgccgtggtggac
ggctgcggcaaggccgcgggcagggcggagccagcggccgaggagtacgcgctcatgtcc
atcgacaccatcatcaacggcaaggaaggcgtgttccccgggctgatccccgtcctgaac
tcctacctggagagcatggaggtggacgtggacaccaggtgcagcatcctgaactacctg
aggctcatcaagaagagggcatccggagaattaatgacagttgccaaatggatgagggag
tttatcgcaaagcatcccgactacaagcaggacagtgtaataactgaccagatgaactat
agccttcttctaaagtgtaatcaaatcgcaaatgaatcatgtgagtgcccagagttactc
ggaccagcgtttaggaaagtaaggtacagtggaagtaaaagcgactcttccacctag
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