Budorcas taxicolor (takin): 128055804
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Entry
128055804 CDS
T08909
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
btax
Budorcas taxicolor (takin)
Pathway
btax00790
Folate biosynthesis
btax01100
Metabolic pathways
btax01240
Biosynthesis of cofactors
btax01523
Antifolate resistance
btax04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
btax00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
128055804 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
128055804 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
128055804 (FPGS)
Enzymes [BR:
btax01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
128055804 (FPGS)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
128055804
NCBI-ProteinID:
XP_052504316
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Position
11:157702354..157715046
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AA seq
585 aa
AA seq
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MSRARCHALFLAAVSPRGATTRVAARRGLSAWPVLQEPDMAYQDAVRTLNTLQTNANYLE
MVKRERGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRSYGL
KTGFFSSPHLVQVRERIRINGQPISSELFTKHFWRLYHRLEETKDDSSCVSMPGYFRFLT
LMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGITSLGIDHTGLLGDTMEKIAWQ
KGGIFKSGVPAFTVLQPDEPLAVLRDRAQQISCPLYLCPPLQALEEGGPPLTLGLEGEHQ
RSNAALALQLARCWLQQKGYQDAGELKASRPSLPGQLPPAPVFQPTPHMQQGLRHTEWPG
RTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALHRCERPDSGSEVRVLLFNSTGDRDSA
ALLKVLQPCQFDYAIFCPNLVEMASTDNADQQNFTVTLDQVLLRCLAHQQHWSCLHEERA
SPDPWSTPGREQGGPASLLLAPHPSHTHGASSLVFSCISHALQWITQGRDPVFQLPSPPR
GLLAHPVAYSGAMVLQEAAAVHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1758 nt
NT seq
+upstream
nt +downstream
nt
atgtctcgggcacgctgccacgctctcttcctggcagcagtttctccgcgtggtgcaaca
accagggtcgcagcgcggcgagggttgagcgcgtggcctgtgctgcaggagccagacatg
gcgtatcaggatgccgtgcgcacactcaacaccctgcagaccaatgctaactacttggag
atggtgaagcgtgagcggggtgacccccagacacagctggaagccatgaagctgtacttg
gcacggagtgggctgcaggtggaggacttggaccaactgaacattatccacatcactggg
accaaggggaagggctccacgtgtgccttcactgaacgtatcctccgaagctatggcctg
aagacggggttctttagctctccccacctggtgcaggtgcgtgagcggatccgcatcaat
gggcagcccataagctccgagctcttcaccaagcacttttggcgcctctaccaccggctg
gaggagaccaaggacgacagtagctgtgtctccatgcctggctacttccgcttcctcacg
ctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggaagtaggc
atcggtggggcttacgactgcaccaacatcatcaggaagcctgtggtgtgtgggatcacc
tctcttggcattgaccacactggccttttgggggacacaatggagaagatcgcatggcag
aaagggggcatttttaagagtggcgtccctgccttcaccgtgctccagcctgacgagccg
ctggcagtgctaagggacagggctcagcagatctcatgtcccctctacctgtgcccacca
ctacaagccctggaggaaggggggccaccgctgaccctgggcctggagggagagcaccag
cggtccaatgctgccctggccttgcagctggcccgctgctggctgcagcagaaaggttac
caggatgctggggagctgaaggcatccaggcccagcctcccggggcagctgcccccagca
cctgtgttccagcccacgccccacatgcagcaggggcttcggcacacggagtggccaggt
cggacgcagttgctgcggcgcgggcctcttacctggtacctggacggcgcgcacaccacc
agcagcatgcaggcctgtgtgcgctggttccgccaggcgctacaccgctgcgagcggccg
gacagtgggtccgaggtgcgcgtcttgctcttcaactccactggggaccgggattccgcg
gccctgctgaaagtgctgcagccctgccagtttgactatgccattttctgccctaacctg
gtagagatggcatcaacagacaatgcagaccaacagaacttcacagtgacactggaccag
gtgctgctccgctgcctcgcccaccaacagcactggagttgcctgcatgaggagcgggcc
agcccggacccttggagcacgcccggccgggagcagggtgggcccgcatctctgctgctg
gcgcctcacccatcccacacccacggtgccagctccctcgtcttcagctgcatctcccac
gccttgcagtggatcacccaaggccgggaccctgtctttcagctgcccagtcccccacgg
ggcctcctcgcccaccctgtggcatacagtggggccatggtactccaagaggctgccgcc
gtccacgtgctggtcacaggcagcctgcacctggtgggcggtgtcctgaagctgctggag
ccctccctgtcccagtag
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