Budorcas taxicolor (takin): 128056816
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Entry
128056816 CDS
T08909
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
btax
Budorcas taxicolor (takin)
Pathway
btax00140
Steroid hormone biosynthesis
btax01100
Metabolic pathways
btax05215
Prostate cancer
Module
btax_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
btax00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
128056816 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
128056816 (SRD5A2)
Enzymes [BR:
btax01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
128056816 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
128056816
NCBI-ProteinID:
XP_052505582
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Position
11:complement(74090904..74137564)
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AA seq
254 aa
AA seq
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MSVRCQQSPVLAGSATLAALGALVLYLAEPSGYGKYSENLMPVAIRLPARAAWFLQELPS
FAVPAGILAGQPSSLLGPPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVVFLFRGFVFCM
GNGLLQGYYLVYCAEYPAEWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEITYRI
PQGGLFTYVSGANFLGEIIEWIGYALASWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFD
DYPKSRRALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgtctgttcgctgccagcagagtccggtgctggcagggagtgccactttggccgccctg
ggggcactggtcctgtacctcgcggagccctccggctacgggaagtactcggagaacctg
atgccggtggctatccgtctgcccgcccgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatactcgcagggcagcccagctctcttttgggtccgcctgcg
actgtgcttctgggcctcttctgcgcacattacttccacaggacatttgtttattcactg
ctcactagagggaggccgtttccagttgtattccttttcagaggctttgtcttctgcatg
ggaaatggactcctccaaggctactatctggtttactgtgctgaataccctgctgagtgg
tacacagacatacggtttagcctgggtgtcttcttattcattttgggaatgggaatcaac
attcacagtgactatatattgcgccagctcaggaagcccggagaaatcacctataggatt
ccacaaggtggcttgttcacgtacgtttctggagccaatttcctcggtgagatcattgaa
tggatcggctatgccctggcctcttggtccctcccagcgcttgcatttgcgtttttctca
ctttgtttccttgggctgcgagcttttcatcatcatagattctacctcaagatgtttgat
gactaccccaagtctcgaagagccctcattccattcatcttttaa
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