KEGG   Budorcas taxicolor (takin): 128065393
Entry
128065393         CDS       T08909                                 
Symbol
PRKCA
Name
(RefSeq) protein kinase C alpha type isoform X1
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
btax  Budorcas taxicolor (takin)
Pathway
btax01521  EGFR tyrosine kinase inhibitor resistance
btax04010  MAPK signaling pathway
btax04012  ErbB signaling pathway
btax04014  Ras signaling pathway
btax04015  Rap1 signaling pathway
btax04020  Calcium signaling pathway
btax04066  HIF-1 signaling pathway
btax04070  Phosphatidylinositol signaling system
btax04071  Sphingolipid signaling pathway
btax04072  Phospholipase D signaling pathway
btax04082  Neuroactive ligand signaling
btax04150  mTOR signaling pathway
btax04151  PI3K-Akt signaling pathway
btax04261  Adrenergic signaling in cardiomyocytes
btax04270  Vascular smooth muscle contraction
btax04310  Wnt signaling pathway
btax04360  Axon guidance
btax04370  VEGF signaling pathway
btax04510  Focal adhesion
btax04540  Gap junction
btax04613  Neutrophil extracellular trap formation
btax04650  Natural killer cell mediated cytotoxicity
btax04664  Fc epsilon RI signaling pathway
btax04666  Fc gamma R-mediated phagocytosis
btax04670  Leukocyte transendothelial migration
btax04713  Circadian entrainment
btax04720  Long-term potentiation
btax04723  Retrograde endocannabinoid signaling
btax04724  Glutamatergic synapse
btax04725  Cholinergic synapse
btax04726  Serotonergic synapse
btax04727  GABAergic synapse
btax04728  Dopaminergic synapse
btax04730  Long-term depression
btax04750  Inflammatory mediator regulation of TRP channels
btax04911  Insulin secretion
btax04912  GnRH signaling pathway
btax04916  Melanogenesis
btax04918  Thyroid hormone synthesis
btax04919  Thyroid hormone signaling pathway
btax04921  Oxytocin signaling pathway
btax04925  Aldosterone synthesis and secretion
btax04926  Relaxin signaling pathway
btax04928  Parathyroid hormone synthesis, secretion and action
btax04929  GnRH secretion
btax04933  AGE-RAGE signaling pathway in diabetic complications
btax04935  Growth hormone synthesis, secretion and action
btax04960  Aldosterone-regulated sodium reabsorption
btax04961  Endocrine and other factor-regulated calcium reabsorption
btax04970  Salivary secretion
btax04971  Gastric acid secretion
btax04972  Pancreatic secretion
btax05017  Spinocerebellar ataxia
btax05022  Pathways of neurodegeneration - multiple diseases
btax05031  Amphetamine addiction
btax05032  Morphine addiction
btax05143  African trypanosomiasis
btax05146  Amoebiasis
btax05161  Hepatitis B
btax05163  Human cytomegalovirus infection
btax05164  Influenza A
btax05170  Human immunodeficiency virus 1 infection
btax05171  Coronavirus disease - COVID-19
btax05200  Pathways in cancer
btax05205  Proteoglycans in cancer
btax05206  MicroRNAs in cancer
btax05207  Chemical carcinogenesis - receptor activation
btax05214  Glioma
btax05223  Non-small cell lung cancer
btax05225  Hepatocellular carcinoma
btax05231  Choline metabolism in cancer
btax05415  Diabetic cardiomyopathy
btax05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:btax00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    128065393 (PRKCA)
   04012 ErbB signaling pathway
    128065393 (PRKCA)
   04014 Ras signaling pathway
    128065393 (PRKCA)
   04015 Rap1 signaling pathway
    128065393 (PRKCA)
   04310 Wnt signaling pathway
    128065393 (PRKCA)
   04370 VEGF signaling pathway
    128065393 (PRKCA)
   04066 HIF-1 signaling pathway
    128065393 (PRKCA)
   04020 Calcium signaling pathway
    128065393 (PRKCA)
   04070 Phosphatidylinositol signaling system
    128065393 (PRKCA)
   04072 Phospholipase D signaling pathway
    128065393 (PRKCA)
   04071 Sphingolipid signaling pathway
    128065393 (PRKCA)
   04151 PI3K-Akt signaling pathway
    128065393 (PRKCA)
   04150 mTOR signaling pathway
    128065393 (PRKCA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    128065393 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    128065393 (PRKCA)
   04540 Gap junction
    128065393 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    128065393 (PRKCA)
   04650 Natural killer cell mediated cytotoxicity
    128065393 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    128065393 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    128065393 (PRKCA)
   04670 Leukocyte transendothelial migration
    128065393 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    128065393 (PRKCA)
   04929 GnRH secretion
    128065393 (PRKCA)
   04912 GnRH signaling pathway
    128065393 (PRKCA)
   04921 Oxytocin signaling pathway
    128065393 (PRKCA)
   04926 Relaxin signaling pathway
    128065393 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    128065393 (PRKCA)
   04918 Thyroid hormone synthesis
    128065393 (PRKCA)
   04919 Thyroid hormone signaling pathway
    128065393 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    128065393 (PRKCA)
   04916 Melanogenesis
    128065393 (PRKCA)
   04925 Aldosterone synthesis and secretion
    128065393 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    128065393 (PRKCA)
   04270 Vascular smooth muscle contraction
    128065393 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    128065393 (PRKCA)
   04971 Gastric acid secretion
    128065393 (PRKCA)
   04972 Pancreatic secretion
    128065393 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    128065393 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    128065393 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    128065393 (PRKCA)
   04727 GABAergic synapse
    128065393 (PRKCA)
   04725 Cholinergic synapse
    128065393 (PRKCA)
   04728 Dopaminergic synapse
    128065393 (PRKCA)
   04726 Serotonergic synapse
    128065393 (PRKCA)
   04720 Long-term potentiation
    128065393 (PRKCA)
   04730 Long-term depression
    128065393 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    128065393 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    128065393 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    128065393 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    128065393 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    128065393 (PRKCA)
   05206 MicroRNAs in cancer
    128065393 (PRKCA)
   05205 Proteoglycans in cancer
    128065393 (PRKCA)
   05207 Chemical carcinogenesis - receptor activation
    128065393 (PRKCA)
   05231 Choline metabolism in cancer
    128065393 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    128065393 (PRKCA)
   05214 Glioma
    128065393 (PRKCA)
   05223 Non-small cell lung cancer
    128065393 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    128065393 (PRKCA)
   05161 Hepatitis B
    128065393 (PRKCA)
   05171 Coronavirus disease - COVID-19
    128065393 (PRKCA)
   05164 Influenza A
    128065393 (PRKCA)
   05163 Human cytomegalovirus infection
    128065393 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    128065393 (PRKCA)
   05143 African trypanosomiasis
    128065393 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    128065393 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    128065393 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    128065393 (PRKCA)
   05032 Morphine addiction
    128065393 (PRKCA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    128065393 (PRKCA)
   05415 Diabetic cardiomyopathy
    128065393 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    128065393 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    128065393 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:btax01001]
    128065393 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:btax04131]
    128065393 (PRKCA)
Enzymes [BR:btax01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     128065393 (PRKCA)
Protein kinases [BR:btax01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   128065393 (PRKCA)
Membrane trafficking [BR:btax04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    128065393 (PRKCA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 C1_2 DUF4656
Other DBs
NCBI-GeneID: 128065393
NCBI-ProteinID: XP_052514540
LinkDB
Position
19:61901220..62194023
AA seq 688 aa
MADVFPAAEPAAPQDAANRFARKGALRQKNVHEVKNHRFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNETFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE
LRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG
TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV
NGGDLMYHIQQVGRFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA
DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG
EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI
DWEKLESREIQPPFKPKVTFCTKMHWLQWASRPSCGKGAENFDKFFTRGQPVLTPPDQLV
IANIDQSDFEGFSYVNPQFVHPILQSAV
NT seq 2067 nt   +upstreamnt  +downstreamnt
atggctgacgtcttcccggccgccgagccggcggcgccgcaggacgcggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaagaaccaccgcttcatc
gcgcgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa
tttgttactttttcttgtccgggggcggataaaggacccgacacggatgacccgaggagc
aagcacaagttcaagatccacacgtatggcagccccaccttctgcgatcactgcgggtcc
ctgctctacggcctcatccaccaggggatgaagtgtgacacctgtgatatgaacgtgcac
aagcagtgtgtgatcaacgtgcccagcctctgtgggatggaccacacggagaagaggggc
cgcatctacctgaaggccgaggtcacggatgaaaagctgcacgtcacagtacgagacgcg
aaaaacctaatccctatggatccgaatgggctttcagatccctatgtgaagctgaagctt
attcctgaccccaagaacgagagcaaacaaaaaaccaagaccatccgctccacgctgaac
ccccagtggaatgagaccttcacgttcaaattaaaaccttctgataaagaccggcggctg
tccgtggagatctgggactgggatcgaactacacggaacgacttcatggggtccctttcc
tttggggtctcggagctgatgaagatgccggccagcggatggtacaagctgctgaaccaa
gaggagggtgagtactacaacgtgccgatccccgaaggcgacgaggaaggcaacgtggag
ctcaggcagaaattcgagaaagccaagcttggccccgccggcaacaaagtcatcagtccc
tccgaggacaggagacagccttccaacaacctggacagggtgaagctcaccgacttcaac
tttctcatggtgctgggcaaaggcagctttggcaaggtgatgctggctgaccggaagggg
accgaggagctgtacgccatcaagatcctgaagaaggacgtggtcatccaggacgacgac
gtggaatgcaccatggtggagaagcgggtgctggctctgctggacaagccgccgttcctg
acacagctgcactcctgcttccagacagtggaccggctctacttcgtcatggagtacgtc
aacggcggggacctcatgtaccacatccagcaggtcgggaggttcaaggagccgcaagca
gtgttctatgcagcagagatttccatcgggctgttcttccttcataaaagaggaatcatt
tatcgggacctgaagttagacaacgtcatgctggactcggaaggacacatcaagatcgcg
gacttcgggatgtgcaaggagcacatgatggacggcgtcacgaccaggaccttctgtggg
acccccgactacatcgccccggagataatcgcctatcagccgtatgggaagtccgtggac
tggtgggcctatggcgtcctgttgtacgagatgttggccgggcagcctccgttcgacggc
gaggacgaggatgagctgttccagtccatcatggagcacaacgtctcgtaccccaagtcc
ttgtccaaggaggccgtgtccatctgcaaagggctgatgaccaagcaccccgggaagcgg
ctgggctgcgggcccgagggcgagcgggatgtgcgggagcacgccttcttccggaggatt
gactgggagaagctggagagccgtgagatccagccgcccttcaagcccaaagtgactttc
tgcaccaaaatgcactggcttcagtgggcgtccaggccttcgtgcggcaaaggagcagag
aactttgacaagttcttcacgcgagggcagcctgtcttgacgccgcccgaccagctggtc
atcgcgaacatcgaccagtctgatttcgaaggcttctcgtacgtcaacccccagttcgtg
caccccatcctgcagagcgcggtatga

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