Budorcas taxicolor (takin): 128066823
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Entry
128066823 CDS
T08909
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
btax
Budorcas taxicolor (takin)
Pathway
btax00230
Purine metabolism
btax01100
Metabolic pathways
btax04927
Cortisol synthesis and secretion
btax04934
Cushing syndrome
btax05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
btax00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
128066823 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
128066823 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
128066823 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
128066823 (PDE8A)
Enzymes [BR:
btax01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
128066823 (PDE8A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PAS_4
DUF5894
SPO22
PAS_12
PAS_8
Motif
Other DBs
NCBI-GeneID:
128066823
NCBI-ProteinID:
XP_052515900
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Position
21:25453130..25597696
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AA seq
753 aa
AA seq
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MRFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFMCTVTKEAQTALACFLDKHHDIIIIDH
RNSRHLDAEALCRSIRSSKLSENTVIIGVVRRVDREESCVMSLIAAGFTRRYIENPSPMA
CYNELLQLEFGEVRSQLKLRACNSMFAALERSQEAIEITSEDHIIQYANPAFETTMGYQS
GELIGKEIAEVPINEKKADLLDTINSCKEWQGIYSVRKKNGDNIQQNVKIIPVIGQGGKI
RHYVSIIRVCNGNNKAEKIAECVQTDSYADNQSGKHKDRRKSSLDVKTVASRTNEVSSQR
RHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQFGAKD
DDPHANDLVGGLVSDGLRRLSGNEYVLSTKNLQQAASSSIVPISLHDVPSQITRAMEKEE
YWDFNIFELEAATHKRPLIYLGLKVFARFGVCEFLKCPEATLRSWLQVIEASYHASNPYH
NSTHSADVLHATAYFLCRERAKQTLDPLDEVGALIAATIHDVDHPGRTNSFLCNAGSELA
ILYNDMAVLEHHHAALAFQLTTGDDKCNIFKNMERNDYQTLRQGIIDMVLATEMTKHFEH
VNKFVNIINKPLAALEEDEETDKDQEAINTMLRTPENRTLIKRMLIKCADVSNPCRPLEQ
CIEWAARISEEYFSQTDEEKQRDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAF
VDLPELMQHLDNNFKYWKGLDDMKLRSLRPPPE
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatccagatcaactccaggtacttttagtgtttaccaaagaagataaccag
tgtaatggattctgcagggcgtgtgaaaaagcagggtttatgtgtacagttaccaaggag
gctcagactgccctcgcctgtttcttggacaaacaccatgacatcatcattatagaccac
agaaattcccgacatctggatgctgaggcgctgtgcaggtctatcagatcatcaaaactc
tcagaaaacacagttattattggtgtagtacgcagagtggatagagaagagtcatgtgta
atgtccctcattgctgctggcttcacaaggaggtatatagaaaaccccagccccatggcc
tgttacaatgaactgctccagctggaatttggagaggtgcgctcacagctgaaactcagg
gcttgtaattcaatgttcgctgcattagagagaagtcaagaagcaattgagattacaagt
gaagaccacattatccagtatgcaaatccagcgttcgaaacaacaatgggctatcagtca
ggtgaattaatagggaaggaaatagcagaagtgcctataaatgaaaaaaaggctgatttg
ctcgatactataaattcatgcaaggaatggcaaggaatttactctgtcaggaagaaaaat
ggagataacatacaacaaaatgtgaagataatacctgtcattggacagggaggaaaaatt
agacactatgtgtccattatcagagtgtgcaatggcaacaataaggcggagaagatagct
gaatgtgttcagaccgacagttatgcagataatcagtcaggcaaacataaagacaggaga
aaaagctccctagatgtcaaaactgttgcctctcgaacaaatgaagtttccagccagaga
cgacactcttcaatggcccggatccattccatgacgatcgaggcgcccatcaccaaggtc
atcaatatcatcaatgctgcccaggaaagcagtcccatgcctgtgacagaagccttagac
cgtgtgctggaaattctaagaaccactgagttatattcgccacagttcggtgctaaggac
gatgatcctcatgccaacgacctcgttgggggcctggtgtctgatggtttgcgaagatta
tccggaaatgagtatgttctttcaacaaaaaaccttcagcaggctgccagcagcagcatc
gtccccatctcccttcatgatgtcccgtcacagataactcgggccatggaaaaggaggag
tactgggacttcaatatttttgaattggaggctgccactcataaaaggcctttgatttac
cttggtctcaaagtgtttgctcgcttcggagtctgtgaattcttaaagtgccctgaggcg
acgctgagatcctggttacaggtgatcgaagccagttaccacgcttccaacccctaccac
aactccacgcactctgccgacgtgctgcacgccactgcctactttctgtgcagagagagg
gccaagcaaactttagacccacttgatgaagtcggtgccctcatcgcagccactatccac
gatgtggaccaccccgggaggaccaactccttcctgtgcaatgccggcagcgagctggcc
attctctacaacgacatggctgtgctggagcaccaccatgcggccttggctttccagctg
accactggcgatgacaaatgcaacatctttaaaaacatggaacggaacgactaccagacg
ctgcgccagggtatcatcgacatggtgttagccacagaaatgacaaagcactttgagcac
gtcaacaaatttgtcaacatcatcaacaagcccttggcagcattagaagaggatgaggaa
actgataaagatcaagaagccataaacaccatgctcaggactccagagaaccggactctg
atcaaaaggatgctgatcaagtgtgctgacgtgtccaacccctgccggcccctggagcag
tgcatcgagtgggctgcacgcatctcagaagagtatttctctcagacagacgaagagaag
caacgggacttgcctgtggtgatgccggtttttgacagaaatacctgcagcatccccaaa
tcccagatctctttcatcgactacttcatcacagacatgtttgatgcctgggacgccttt
gtagacctgcccgagttaatgcagcatctcgacaacaactttaaatactggaaaggactg
gacgacatgaagctgcggagcctgcgcccgcctcccgagtag
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