Budorcas taxicolor (takin): 128068147
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Entry
128068147 CDS
T08909
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
btax
Budorcas taxicolor (takin)
Pathway
btax00230
Purine metabolism
btax00670
One carbon pool by folate
btax01100
Metabolic pathways
btax01523
Antifolate resistance
Module
btax_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
btax00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
128068147 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
128068147 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
128068147 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
btax04147
]
128068147 (ATIC)
Enzymes [BR:
btax01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
128068147 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
128068147 (ATIC)
Exosome [BR:
btax04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
128068147 (ATIC)
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GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
128068147
NCBI-ProteinID:
XP_052517204
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Position
2:147869693..147898025
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AA seq
592 aa
AA seq
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MAPGQLALFSVSDKTGLVEFARNLASVGLNLIASGGTAKALRDADLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDSADMAKLDFSLIRVVVCNLYPFGKTVASPGVTVEEA
IEHIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVASEMRDSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKEYSKGVSQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELREALGLPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLHKTLTPIA
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYENEALKILSKKKNG
NYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNSVVNRSLFSNIVTKNKDLPESAFRDLIV
ATVAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKA
GVKRAEISNAIDQYVTGTIGEGEDLIKWKALFEEVPELLTETEKKEWVDKLNEVSVSSDA
FFPFRDNIDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgctttatttagtgtctctgacaaaactggccttgtggagttt
gccaggaacttagcttctgttggtttgaatctgatcgcctctggagggactgcaaaagcc
ctcagagatgctgatttggcagtcagagatgtatctgagctaactggatttcctgaaatg
ctaggggggcgtgtaaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagatagtgctgacatggccaaacttgatttcagtcttataagagttgttgtt
tgtaatctgtatccctttgggaagacagtggcttctccaggtgtaactgttgaagaggct
attgaacatattgatattggaggagtgactctgctaagagccgcagccaaaaaccatgct
cgagtgacagtcgtgtgtgagccggaggactatgcagctgtagcctcagagatgcgggac
tctgacagcaaagacacatccttggagacaagacgccaattagccttgaaggcttttact
catacagcacagtatgatgaagcaatctcagattacttcaggaaagagtacagtaaaggg
gtatctcagatgcccctgaggtatggaatgaaccctcatcagactcctgcccagctgtat
accctgaagcccaagctccctatcacagttctgaatggagcccctggatttataaacttg
tgtgatgctttgaacgcctggcagctggtgaaggagctcagagaagctttaggccttcca
gccgctgcatctttcaaacatgttagcccagcaggtgctgctgttggaattccactcagt
gaagatgaagccaaagtctgcatggtctatgatctgcacaaaaccctcacacccatagcc
actgcatatgcaagagcaagaggggctgataggatgtcttcgtttggtgactttgttgca
ttatctgatgtttgtgatgtccctactgccaagattatctccagagaggtatctgatggt
attattgccccgggatatgaaaatgaagctttgaaaatactttccaaaaagaaaaacggg
aattactgtgttcttcagatggaccagtcttacaatccagatgaaaatgaagttcgaact
ctctttggtcttcgtttaagccagaagagaaataatagtgttgtcaacaggtcactgttt
agcaacattgttaccaagaataaagatttgccggaatctgcgttcagggacctcatcgtg
gccactgttgctgtcaagtacactcagtctaactccgtgtgctatgccaagaatgggcag
gttattggcatcggagcaggacagcagtctcgtatacactgcacacgccttgcaggtgat
aaggcaaactattggtggcttagacatcacccacaagtgctttccatgaagtttaaagct
ggcgtgaagagagcagaaatctccaatgccatcgatcagtatgttactggaactatcggc
gagggtgaagatttgatcaagtggaaggccctgtttgaggaggtccctgagctgttaact
gagacagaaaaaaaggaatgggttgacaaacttaatgaagtttccgtcagctctgatgcc
ttctttcctttccgggacaatatagacagagctaaaaggagtggcgtggcctacatcgct
gccccttccggttctgccgctgacaaagttgtgatcgaggcttgcgatgagctgggaata
atccttgctcacacgaatctccggctcttccatcactga
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