KEGG   Budorcas taxicolor (takin): 128068545
Entry
128068545         CDS       T08909                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
btax  Budorcas taxicolor (takin)
Pathway
btax00562  Inositol phosphate metabolism
btax01100  Metabolic pathways
btax04015  Rap1 signaling pathway
btax04020  Calcium signaling pathway
btax04022  cGMP-PKG signaling pathway
btax04062  Chemokine signaling pathway
btax04070  Phosphatidylinositol signaling system
btax04071  Sphingolipid signaling pathway
btax04072  Phospholipase D signaling pathway
btax04081  Hormone signaling
btax04082  Neuroactive ligand signaling
btax04261  Adrenergic signaling in cardiomyocytes
btax04270  Vascular smooth muscle contraction
btax04310  Wnt signaling pathway
btax04371  Apelin signaling pathway
btax04540  Gap junction
btax04611  Platelet activation
btax04613  Neutrophil extracellular trap formation
btax04621  NOD-like receptor signaling pathway
btax04713  Circadian entrainment
btax04720  Long-term potentiation
btax04723  Retrograde endocannabinoid signaling
btax04724  Glutamatergic synapse
btax04725  Cholinergic synapse
btax04726  Serotonergic synapse
btax04728  Dopaminergic synapse
btax04730  Long-term depression
btax04742  Taste transduction
btax04750  Inflammatory mediator regulation of TRP channels
btax04911  Insulin secretion
btax04912  GnRH signaling pathway
btax04915  Estrogen signaling pathway
btax04916  Melanogenesis
btax04918  Thyroid hormone synthesis
btax04919  Thyroid hormone signaling pathway
btax04921  Oxytocin signaling pathway
btax04922  Glucagon signaling pathway
btax04924  Renin secretion
btax04925  Aldosterone synthesis and secretion
btax04926  Relaxin signaling pathway
btax04927  Cortisol synthesis and secretion
btax04928  Parathyroid hormone synthesis, secretion and action
btax04929  GnRH secretion
btax04933  AGE-RAGE signaling pathway in diabetic complications
btax04934  Cushing syndrome
btax04935  Growth hormone synthesis, secretion and action
btax04961  Endocrine and other factor-regulated calcium reabsorption
btax04970  Salivary secretion
btax04971  Gastric acid secretion
btax04972  Pancreatic secretion
btax04973  Carbohydrate digestion and absorption
btax05010  Alzheimer disease
btax05016  Huntington disease
btax05017  Spinocerebellar ataxia
btax05022  Pathways of neurodegeneration - multiple diseases
btax05142  Chagas disease
btax05143  African trypanosomiasis
btax05146  Amoebiasis
btax05163  Human cytomegalovirus infection
btax05200  Pathways in cancer
btax05415  Diabetic cardiomyopathy
btax05417  Lipid and atherosclerosis
Module
btax_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:btax00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    128068545 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    128068545 (PLCB3)
   04310 Wnt signaling pathway
    128068545 (PLCB3)
   04371 Apelin signaling pathway
    128068545 (PLCB3)
   04020 Calcium signaling pathway
    128068545 (PLCB3)
   04070 Phosphatidylinositol signaling system
    128068545 (PLCB3)
   04072 Phospholipase D signaling pathway
    128068545 (PLCB3)
   04071 Sphingolipid signaling pathway
    128068545 (PLCB3)
   04022 cGMP-PKG signaling pathway
    128068545 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    128068545 (PLCB3)
   04081 Hormone signaling
    128068545 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    128068545 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    128068545 (PLCB3)
   04613 Neutrophil extracellular trap formation
    128068545 (PLCB3)
   04621 NOD-like receptor signaling pathway
    128068545 (PLCB3)
   04062 Chemokine signaling pathway
    128068545 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    128068545 (PLCB3)
   04922 Glucagon signaling pathway
    128068545 (PLCB3)
   04929 GnRH secretion
    128068545 (PLCB3)
   04912 GnRH signaling pathway
    128068545 (PLCB3)
   04915 Estrogen signaling pathway
    128068545 (PLCB3)
   04921 Oxytocin signaling pathway
    128068545 (PLCB3)
   04926 Relaxin signaling pathway
    128068545 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    128068545 (PLCB3)
   04918 Thyroid hormone synthesis
    128068545 (PLCB3)
   04919 Thyroid hormone signaling pathway
    128068545 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    128068545 (PLCB3)
   04916 Melanogenesis
    128068545 (PLCB3)
   04924 Renin secretion
    128068545 (PLCB3)
   04925 Aldosterone synthesis and secretion
    128068545 (PLCB3)
   04927 Cortisol synthesis and secretion
    128068545 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    128068545 (PLCB3)
   04270 Vascular smooth muscle contraction
    128068545 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    128068545 (PLCB3)
   04971 Gastric acid secretion
    128068545 (PLCB3)
   04972 Pancreatic secretion
    128068545 (PLCB3)
   04973 Carbohydrate digestion and absorption
    128068545 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    128068545 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    128068545 (PLCB3)
   04725 Cholinergic synapse
    128068545 (PLCB3)
   04728 Dopaminergic synapse
    128068545 (PLCB3)
   04726 Serotonergic synapse
    128068545 (PLCB3)
   04720 Long-term potentiation
    128068545 (PLCB3)
   04730 Long-term depression
    128068545 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    128068545 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    128068545 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    128068545 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    128068545 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    128068545 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    128068545 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    128068545 (PLCB3)
   05142 Chagas disease
    128068545 (PLCB3)
   05143 African trypanosomiasis
    128068545 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    128068545 (PLCB3)
   05016 Huntington disease
    128068545 (PLCB3)
   05017 Spinocerebellar ataxia
    128068545 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    128068545 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    128068545 (PLCB3)
   05415 Diabetic cardiomyopathy
    128068545 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    128068545 (PLCB3)
   04934 Cushing syndrome
    128068545 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:btax04131]
    128068545 (PLCB3)
Enzymes [BR:btax01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     128068545 (PLCB3)
Membrane trafficking [BR:btax04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    128068545 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    128068545 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 128068545
NCBI-ProteinID: XP_052517632
LinkDB
Position
25:43310579..43327004
AA seq 1234 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDSNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNKQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRLGSGVPDS
SVRKRPLEQSNSALSESSATTEPSSPQLGSPSSDSCPGLSNGEEAGLEKPSLEPRKSLGE
EGLQRGPDALGPAYREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANAVRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP
FDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQSGPETSQETQTQQL
GYQLNPHPTPSPLDASPRRPPGPATSPTSSSISSSISSPGQRDDLIASILSEVAPAPLDE
LRGHKALVKLRSRQERDFRELYKKHQRKAVALTRRLLDNLAQARAGSRCRQRPGVLSGED
ERAEEEEVSRYQEFQKKQVQSLLELREAQVDTEAERRLEHLQQAQLKLREVVLDAHMTQL
KKLKEINEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLE
EAQKQRQERLVAGQQQVLQQLAEEEPKLLAQLVQECQEQRERLPQEIRWSLLGETPEGLG
DGHLVACASNGHAPGSSGHLPGADSESQEETTKL
NT seq 3705 nt   +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtcgtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctccagtcggaacctg
gtaaccctgcgtgtggactccaatggcttcttcctgtattggacgggacccaacatggag
gtggacacactcgacatcagttccatcagggacaccaggacgggccgttatgcccgcctg
cccaaggaccccaagatccgggaggtgttgggcttcgggggccctgatgcccggttggag
gagaagctgatgacagtggtggctgggccagacccggtgaatacaacattcttgaacttc
atggccgtgcaggacgatacagccaaggtctggtccgaggagctcttcaagttggctatg
aacatcctggctcagaacgcctcccggaacaccttcttgcgcaaagcatacacgaagctg
aagctgcaggtaaaccaggatggacggattccagtcaagaacatcctgaagatgttctca
gcagacaagaagcgggtagaaactgcactggaatcctgtggcctcaatttcaaccgaagc
gagtccatccggcctgacgagttttccttggaaatcttcgagcggttcctgaacaagctg
tgtctgcggccggacattgacaagatcctgctggagataggcgccaagggcaaaccttac
ctgacactggagcagctcatggatttcatcaaccagaagcagcgggacccgcggctcaac
gaagtactgtacccgcctctgcggccctcccaggcccggctgctcatcgagaagtacgag
cccaacaagcagttcctggagcgagaccagatgtccatggagggcttcagccgctacctg
ggaggtgaggagaacggcattctgccgcttgaggccttggatctgagcgcagacatgacc
cagccgctcagtgcctacttcatcaattcctcgcataacacctatctcacggcgggacag
ctggccggaacctcgtcggtggagatgtaccggcaggcgctgttgtggggctgccgctgc
gtggagctggacgtgtggaaggggcggccgcccgaggaggagccgttcatcacgcacggc
ttcaccatgaccacggaggtgccgctgagagacgtactcgaggccatcgcggagaccgcc
ttcaagacctcgccctaccccgtcatcctctcctttgagaaccacgtggactcggcgaaa
cagcaggccaagatggccgagtactgccgctccatctttggggatgctctgctcatcgac
cccctggacaagtacccgctggccccgggcgtccccctgcccagcccccaggacctgatg
ggccgcatcctggtgaagaacaagaagcggcaccgactcggcagcggcgtccctgacagc
tccgtgcgcaagcggccgctggagcagagcaactcggccctgagcgagagctccgccacc
accgagccctcttcgccccagcttgggtcccccagctctgacagctgcccaggcctgagc
aatggggaggaggcgggcctcgagaagcccagcctggagcctcggaagtctctgggggag
gagggtttgcagcggggccctgatgctcttggacctgcctaccgggaggatgaggaggag
gacgaggaagaggaggaacagacggaccccaaaaagccgaccacggatgagggcaccgcc
agcagtgaggtcaacgccactgaggaaatgtccacactcgtcaactacattgagcctgtc
aagttcaagtccttcgaggctgctcgaaagaggaacaagtgcttcgagatgtcatccttc
gtggagaccaaggccatggagcaactgaccaagagccccatggagttcgtggaatacaac
aagcagcagctcagccgcatctaccccaagggcacccgcgtggactcgtccaactatatg
ccccagctcttctggaacgtgggctgccagctcgttgcactcaacttccagaccctggat
gtgccgatgcagctcaacgccggtgtgtttgagtacaacgggcgcagtggctacctactc
aagcctgagttcatgcggcggccggacaagtcctttgaccccttcaccgaagtcatcgtg
gacggcatcgtggccaatgctgtgcgggtcaaggtgatctcggggcagttcctgtccgac
aggaaggtgggcatctacgtggaggtggacatgttcgggctccctgttgacacacggcgc
aagtaccgcacgcggacctcacaggggaactcgttcaaccccgtgtgggatgaggagcca
ttcgacttccccaaggtggtgctgcccacgctggcttcgctgcgcatcgcggcctttgag
gaggggggcaagttcgtggggcaccggatcctgcctgtctccgccatccgctcagggtac
cattacatctgcctgcggaacgaggccaaccagccactgtgcctgccagccctgctcatc
tacaccgaggcctccgactacatccccgatgaccaccaggactatgcagaggccctgatc
aaccccatcaagcatgtcagcctgatggaccagagggccaagcagctggctgccctcatt
ggggagagcgaggctcagtctggcccggagacaagccaggagacccagactcagcagctg
gggtaccaactgaacccacaccccacgcccagcccactggatgcctccccgcgccggccc
ccaggccccgccacctccccgaccagctcctccatcagctcctccatcagcagcccaggt
cagcgcgatgatctcatcgccagcatcctctcagaggtggccccggccccactggatgag
ctccgaggccacaaggccctggtgaagctccggagccggcaagagcgagacttccgggag
ctgtacaagaaacatcagcggaaggctgttgccctcacgcgccggttgctcgacaacctg
gcccaggcccgcgcggggagcaggtgccgacagcggcccggtgtcctaagcggggaggac
gagagggcagaagaggaagaggttagcaggtatcaagagttccagaagaaacaggtgcag
agtctgctggagctgagggaggcccaggtggacacggaggcggagcggaggctagagcat
ctgcagcaggctcagctgaagctcagggaggttgtcctggacgctcacatgactcagttg
aagaaactgaaggagataaacgagagggagaagaaggaactgcagaagatcctggacagg
aaacgccacaacagtatctcagaggccaagaccagggagaaacacaagaaggaggcggaa
ctgacagaaattaaccggcggcacatcactgagtcagtcaactccatccgtcggctggag
gaggcccagaagcagcggcaggaacgccttgtggccgggcagcagcaggtcctccaacag
ctggcggaagaggagcccaagctgctggcccagctggtccaggagtgtcaggagcagcgg
gagaggctgccccaggagatccgctggagcctgctgggcgagacaccggagggactgggg
gacgggcatctggtcgcctgtgccagcaacggtcacgcgcctgggagcagcgggcacctg
cctggcgctgactcagagagccaggaggagactacaaagctctga

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