Burkholderia thailandensis USAMRU Malaysia #20: BTRA_119
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Entry
BTRA_119 CDS
T03391
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bthm
Burkholderia thailandensis USAMRU Malaysia #20
Pathway
bthm00290
Valine, leucine and isoleucine biosynthesis
bthm00620
Pyruvate metabolism
bthm01100
Metabolic pathways
bthm01110
Biosynthesis of secondary metabolites
bthm01210
2-Oxocarboxylic acid metabolism
bthm01230
Biosynthesis of amino acids
Module
bthm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bthm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BTRA_119 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BTRA_119 (leuA)
Enzymes [BR:
bthm01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BTRA_119 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
BP74_N
Motif
Other DBs
NCBI-ProteinID:
AIC86508
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Position
1:144947..146587
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AA seq
546 aa
AA seq
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MKRNPAEKYRPFEPVRINGRRWPSRTIERAPIWMSTDLRDGNQSLIEPMTIEQKLEFFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIVEKRIPDDVTIEVLVQSREDLIAHTFDALEGA
PRAIVHLYNAICPSFRRIVFGMSKDDVKALAVDGTRIIKEHAQARPGTHWTFQYSPETFS
MTELPFAREVCDAVAQTWRPTRDHKMIVNLPATVEAATPNVFADQIEWMDRNLGYRDSIV
LSVHPHNDRGTAVAAAELALLAGADRIEGCLFGNGERTGNVDLVTLALNLYTQGIDPGLD
FSDIDAVRRVVERCNRIPVHPRHPYAGDLVFTAFSGSHQDAIRKGLAQQRPDAIWEVPYL
PIDPADLGRSYDAVIRVNSQSGKGGATYLLERGMGFSPPRRVQIEFSHAVQALADASGEE
VTADAICALFTREYLQTMGPAARAGASASWHDREVALAHAEDAPSAARQAAAAFAAAAGV
AIDVTSCEVERTANGDTVVFVGAKVGDAALRHGAGVHRDPAAAATDAVASAINRSAWSRD
KRRAAA
NT seq
1641 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgcaaccccgccgagaaataccgaccgttcgaacccgttcgcatcaacggacgc
cgatggccgagccgcacgatcgagcgcgcgccgatctggatgagcaccgatctgcgcgac
ggcaaccagtcgttgatcgagccgatgacgatcgagcagaagctcgaattcttcgagatg
ctcgtcgcgatcggcttcaaggaaatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgtgcgcaagctgatcgtcgagaagcgcatccccgacgacgtgacgatcgaa
gtgctcgtgcagtcgcgcgaagacctgatcgcgcacacgttcgacgcgctcgaaggcgcg
ccgcgcgcgatcgtccatctgtacaacgcgatctgcccgtcgttccgccggatcgtgttc
gggatgtcgaaggacgacgtgaaggcgctcgccgtcgacggcacgcgaatcatcaaggag
cacgcgcaggcgcgccccggcacgcactggacgttccagtactcgcccgagacgttcagc
atgaccgagctgccgttcgcgcgcgaagtctgcgacgcggtcgcgcagacgtggcggccg
acgcgcgatcacaagatgatcgtgaacctgcccgccaccgtcgaggccgcgacgccgaac
gtgttcgccgaccagatcgaatggatggaccgcaacctcggctaccgcgacagcatcgtg
ctgtcggtgcacccgcacaacgatcgcggcaccgcggtcgcggcggccgagctggcgctg
ctcgcgggcgcggaccgcatcgaaggatgcctgttcggcaacggcgagcgcacgggcaac
gtcgatctcgtcacgctcgcgctgaacctgtacacgcaagggatcgatccgggcctcgat
ttctccgacatcgacgcggtgcgccgcgtcgtcgaacgctgcaaccggattcccgtgcat
ccgcgccatccgtacgcgggcgatctcgtgttcaccgcgttctccggctcgcatcaggac
gcgatccgcaagggcctcgcgcagcagcggcccgacgcgatctgggaggtgccgtacctg
ccgatcgaccccgccgacctcggccgcagctacgacgccgtgatccgcgtgaacagccag
tccggcaagggcggcgcgacgtacctgctcgagcgcgggatgggcttctcgccgccgcgt
cgcgtgcagatcgaattcagccacgcggtgcaggcgctcgccgacgcgtccggcgaggaa
gtgacggcagacgccatttgcgcgctcttcacgcgcgaatatctgcagacgatgggcccg
gccgcgcgcgcgggcgcgtcggcgagctggcatgaccgcgaagtcgcgctcgcgcacgcc
gaagacgcgccgagcgcggcgcggcaggccgcggccgcattcgccgcggcggcgggcgtc
gcgatcgacgtcacgtcgtgcgaggtcgagcgcaccgcgaacggcgacaccgtcgtgttc
gtcggcgcgaaagtcggcgacgccgcgctgcgccacggcgcgggcgtgcatcgcgatccg
gccgcggccgcgacggacgcggtcgcgagcgcgatcaaccgctcggcctggagccgcgac
aagcggcgcgccgcggcctga
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