Buchnera aphidicola APS (Acyrthosiphon pisum): BU194
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Entry
BU194 CDS
T00036
Symbol
thrA
Name
(GenBank) aspartokinase I / homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
buc
Buchnera aphidicola APS (Acyrthosiphon pisum)
Pathway
buc00260
Glycine, serine and threonine metabolism
buc00261
Monobactam biosynthesis
buc00270
Cysteine and methionine metabolism
buc00300
Lysine biosynthesis
buc01100
Metabolic pathways
buc01110
Biosynthesis of secondary metabolites
buc01120
Microbial metabolism in diverse environments
buc01230
Biosynthesis of amino acids
Module
buc_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
buc_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
buc00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
BU194 (thrA)
00270 Cysteine and methionine metabolism
BU194 (thrA)
00300 Lysine biosynthesis
BU194 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
BU194 (thrA)
Enzymes [BR:
buc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
BU194 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
BU194 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
BBS2_N
Motif
Other DBs
NCBI-ProteinID:
BAB12911
UniProt:
P57290
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All DBs
Position
complement(209246..211696)
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AA seq
816 aa
AA seq
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MKLLKFGGTSLANAEKFLSVSSIIEENTQTDQIAVVLSAPAKITNYLVKIIENTIKNNQI
LETVHLAENIFMQLINNFLNIQSNFPHKEIEKIIKKEFNELKNIIQGILLLKQCPDNIRA
IIISRGEILSVFIMKSILQSKNYNVTIINPVKNLVAIGDNYLDSTVDISESKKNIQNMNI
NQSNIILMAGFIAGNKDKKLVVLGRNGSDYSAAVLAACLDANCCEIWTDVDGVFTSDPRK
VPNARLLKSISYQEAMELSYFGAKVLHPRTIEPIAQFKIPCLIKNTNNVKSIGTLICEQN
CSEKDFLKGVTHLDEIAMFNISGPHIKDVGSVISRIFTMMSRGNIKILLITQSSSENKIN
FCVYEHDIYKILYLFNKEFQLELKDGLLNPFKIKKNLSILSIVGSNIYKKHNIASKIFSV
LGALKINVIAISQGSSKHSISLVIKKENILKAVQHVHNTLFFNKKTIHMFLIGIGGIGST
LLNQILKQKQFLDKKNIEIKICAIANSKKILLLDNTNDLSNWKNDFKKSTQKFNLELLNN
LIKNNHFSNSVIVDCTSSQLLSEQYVNFIDNNFHVVTSNKKANTSEWNYYKKIRKSVAQT
GKKFLYETNVGAGLPVIETLQNLFKSGDNLICFKGILSGSLSFIFGRLEEGILLSQATRE
AKELGFTEPNPCDDLSGIDVARKLLILARESGYNIELKDIKIEPLLPNNFKIYEDTDKFL
LKLKELDVYFSNKIKQALNVGNVLRFVATIEQKRQFFIKLEEVNINNPLYKVKNGENALA
FYTNYYQPIPLVLRGYGAGNNVTASGVFSDLLRTLS
NT seq
2451 nt
NT seq
+upstream
nt +downstream
nt
atgaaattattaaaatttggtggtacatcattagctaatgcagaaaaatttttatctgta
tctagtattattgaagaaaacactcaaacagatcaaattgcggtagtactttctgcacca
gctaaaattactaactatctagtaaaaattatagaaaacactattaagaataatcaaatt
ttagaaacagtacatcttgcagaaaatatatttatgcaactaataaacaattttttaaat
atacaatctaattttcctcataaagaaatagaaaaaattataaaaaaagaatttaatgag
ttaaaaaatatcatacaagggattttattattaaaacagtgtccagataatattcgtgca
attataatttctcgtggagaaatactttcagttttcataatgaaaagtatattacaatct
aaaaattataatgtaactattattaatcctgttaaaaatttagttgctataggtgataat
tatcttgattcaactgttgatatatctgaatctaaaaaaaatattcagaacatgaatatt
aatcaaagtaatattattttaatggctggttttattgcgggaaataaagataaaaaatta
gtggtattaggacgaaatggttctgattattcagctgcggtgttagcggcttgtttagat
gcgaattgttgtgaaatctggactgatgttgacggagtttttacttctgatccaagaaaa
gttccaaatgctcgtttattaaaatcaatatcatatcaagaagcaatggaactgtcttat
ttcggtgctaaggtgctacaccctcgtactattgaaccaattgctcaatttaaaattcca
tgtttaattaaaaatacaaataatgttaaatctattggaacattaatttgcgaacaaaac
tgttccgaaaaagatttcctaaaaggggttactcatcttgatgaaatagcaatgtttaat
atatctggacctcatataaaagatgtaggaagtgtaatttcacgtatatttacaatgatg
tctagaggaaatattaaaatattattaattactcaatcatcttcagaaaataaaattaat
ttctgtgtttacgaacatgatatttataaaattttatatttattcaataaagaatttcaa
ctagaattaaaagatggtttgttgaatcccttcaaaataaagaaaaatttatctatcctc
tcaatagtaggatcgaatatctataaaaaacacaatattgcgtcaaaaatattttctgtt
ctaggcgctttaaaaatcaacgtcattgcaatctcacaaggttcttcgaaacattctatt
tcattagtgattaaaaaagaaaacattttaaaagctgttcaacatgttcataatacattg
ttttttaataaaaaaactattcatatgtttttaataggaataggtggaattggcagtaca
ttactgaaccaaatattaaaacaaaaacaatttttagataaaaaaaatatagaaattaaa
atttgtgctattgcaaattctaaaaaaatattattgttagacaatacaaatgatttatct
aactggaaaaatgattttaaaaaatcaactcaaaaatttaatttagaattgttaaataat
ctaataaaaaataatcatttttcaaactcagtcattgtagattgtacatctagtcaatta
ttatccgaacaatatgtaaattttattgataataattttcatgtcgttacttcaaataaa
aaagcaaataccagcgaatggaattactataaaaaaataagaaagtctgtggctcaaaca
ggtaaaaaatttctatatgaaactaatgtcggtgctggattacctgtaatagaaactctt
caaaatttatttaaatcgggtgataatttaatttgttttaaaggtatattatctggatca
ctatcttttatatttggaagattagaagaaggtattttgttatcacaagctactagagaa
gctaaggaattgggttttactgaaccaaacccgtgtgatgatttatcaggtatagatgta
gcacgaaaattactaattttagcacgtgaatctggatataatatagaattaaaagatatt
aaaattgaacctttattgccaaataattttaaaatatatgaggacactgataaattttta
ttaaaattaaaagaactagacgtatatttttcaaataaaatcaaacaggcgcttaatgta
ggtaatgtattacgatttgtagcaacaatagaacaaaaaagacaattttttataaaactt
gaagaagttaatattaataatccattatacaaagtaaaaaatggtgaaaatgcactagca
ttttatactaattattatcaaccaattcctctggtactaagaggctacggtgctggtaac
aatgttacggcgtctggagtattttccgacttactgcgtacactatcataa
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