KEGG   Burkholderia humptydooensis MSMB43: AQ610_20240
Entry
AQ610_20240       CDS       T04266                                 
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
bud  Burkholderia humptydooensis MSMB43
Pathway
bud00280  Valine, leucine and isoleucine degradation
bud00640  Propanoate metabolism
bud00785  Lipoic acid metabolism
bud01100  Metabolic pathways
bud01110  Biosynthesis of secondary metabolites
bud01210  2-Oxocarboxylic acid metabolism
Module
bud_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:bud00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    AQ610_20240
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    AQ610_20240
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    AQ610_20240
Enzymes [BR:bud01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     AQ610_20240
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: ALX44872
LinkDB
Position
2:182554..183642
AA seq 362 aa
MTTVASFDIDYTQYLGPDGEPVQPLPAFAQDAAALLPLYRAMVLTRAFDTKAVALQRTGK
IGTFASSIGQEAIGVGVASAMRADDVLFPSYRDHAAQFLRGVTMTESLLYWGGDERGSDF
TAARLDFPNCVPIATQVCHAAGAAYAFALRGEARVAVAVLGDGGTSKGDFYEAMNLAGAW
RVPLVIVVNNNQWAISMPRARQTAARTLAQKAIAAGIEGRQIDGNDIVAVRQAVGEAIEN
ARRGGGPALVEALSYRLGDHTTADDATRYRDADALGKQWAFEPLLRLRKHLMRRNVWDDA
QDEAFGKACYAQVEEAVRAYLAVPQPAASAMFDHLYASLPHAMQEQLATALAFAPAAENH
HG
NT seq 1089 nt   +upstreamnt  +downstreamnt
atgaccacggtcgccagcttcgatatcgattacacgcaatacctcggcccggacggcgag
ccggtccagccgctgcccgcgttcgcgcaggacgcggccgcgctgctgccgctctaccgc
gcgatggtgctcacgcgcgcgttcgacacgaaagcggtcgcgctgcagcgcaccggcaag
atcggcacgttcgcgtcgtcgatcgggcaagaggcgatcggcgtgggcgtcgcgagtgcg
atgcgcgccgacgacgtgctgtttccgtcgtatcgcgatcacgccgcgcaattcctgcgc
ggcgtgacgatgacggaaagcctgctgtattggggcggcgacgagcgcggcagcgatttc
acggccgcgcggctggattttccgaattgcgtgccgatcgccacgcaggtgtgccatgcg
gcgggcgccgcttatgcgttcgcgctgcgcggcgaagcgcgcgtcgccgtggccgtgctc
ggcgacggcggcacgtcgaagggcgatttctacgaagcgatgaacctcgcgggcgcgtgg
cgcgtgccgctcgtcatcgttgtcaacaacaaccagtgggcgatctcgatgccgcgcgcg
cggcagaccgccgcgcgcacgctcgcgcaaaaggcgatcgccgccggcatcgaagggcgg
cagatcgacggcaacgatatcgtcgccgtgcggcaggccgttggcgaagcgatcgaaaac
gcgcggcgcggcggcggcccggcgctcgtcgaggcgctcagctatcggctcggcgatcac
acgacggcggacgacgcgacgcgctatcgcgatgccgacgcgctcggcaagcaatgggcg
ttcgagccgctgctgcggctgcgcaagcatctgatgcgtcgcaacgtatgggacgacgcg
caggacgaagcgttcggcaaggcgtgctacgcgcaggtcgaggaagcggtgcgcgcctat
ctcgcggtgccgcagccggccgcgtcggcgatgttcgatcatctgtacgcgagcctgccg
cacgcgatgcaggaacagttggcgacggcgctcgcgtttgcgccggccgcggagaatcat
catggctga

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