Burkholderia sp. PAMC 26561: AXG89_00350
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Entry
AXG89_00350 CDS
T05481
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bum
Burkholderia sp. PAMC 26561
Pathway
bum00290
Valine, leucine and isoleucine biosynthesis
bum00620
Pyruvate metabolism
bum01100
Metabolic pathways
bum01110
Biosynthesis of secondary metabolites
bum01210
2-Oxocarboxylic acid metabolism
bum01230
Biosynthesis of amino acids
Module
bum_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bum00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AXG89_00350
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AXG89_00350
Enzymes [BR:
bum01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AXG89_00350
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
GARS_C
DUF7812
Motif
Other DBs
NCBI-ProteinID:
AME22508
UniProt:
A0A125SEK3
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Position
1:complement(68586..70130)
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AA seq
514 aa
AA seq
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MADKLIIFDTTLRDGEQSPGASMTKDEKIRIAKALERMKVDVIEAGFAASSNGDFDAIHT
IAGLIKDSTICSLARANDKDIQRAADALKPADHFRIHTFIATSALHMEKKLRMSADQVYE
QARLATRFARKFTDDVEFSPEDGSRSDLDFLCRVLEAVIDEGATIINIPDTVGYAVPEGY
GNLIKTIRERVPNSDKAIWSVHCHDDLGMAVANSLAGVHIGGARQIECTINGLGERAGNT
ALEEVVMAMKTRKDYYGLELGIDTTHIVPTSKLVSQITGFVVQPNKAVVGANAFAHASGI
HQDGVLKARDTYEIMRAEDVGWATNKIVLGKLSGRNAFKQRLEDLGVTLESETDVNAAFV
RFKELADRKSEIFDEDIMAIVSEESAEMQAKETFRFVSLAQRSETGEQPHARVVFAVDGI
EVHGESRGNGPVDATLHAIESKVTSGAELVLYSVNAITTGTQAQGEVTVRLSKSGRIVNG
VGTDPDIVAASAKAYLAALNKLHSKVEKLNPQLS
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atggcagacaaactcatcattttcgacacgacgcttcgcgatggcgagcaatcccccggc
gcgtcgatgacgaaagacgagaagatccgcatcgcaaaagcactcgaacggatgaaagtc
gatgtgatcgaagcgggctttgcagccagttccaacggcgatttcgatgcaatccacact
attgccggcctgatcaaggacagcacgatctgctcgctcgcccgcgccaacgacaaagac
atccagcgcgccgccgacgccctcaaacccgccgatcacttccgcattcatacgttcatc
gcgacgtccgcgctgcatatggaaaagaagctgcgcatgagcgccgatcaggtctacgag
caggctcgtctcgccacgcgtttcgcgcgcaagttcacggacgacgtggaattctcgccg
gaagacggcagccgctcggatctcgacttcttgtgccgcgtgctggaagcggtgatcgac
gaaggcgcgaccatcatcaatattccggacaccgtgggttatgccgtgccggaaggttac
ggcaacctgatcaagaccattcgcgaacgcgtgccgaattcggacaaggcgatctggtcc
gtgcattgccacgacgaccttggcatggccgtcgccaattcgctcgctggcgtgcatatc
ggcggcgcgcgtcagatcgagtgcaccatcaacggtctcggcgagcgcgcgggtaacacg
gcgctggaagaagtcgtgatggcgatgaaaacgcgcaaggattattacgggctggaactg
ggtatcgacaccacgcacattgtgccgacgtccaagcttgtctcgcagatcacgggtttt
gtcgtgcagccgaacaaggctgtggtgggcgcaaacgcgttcgcgcatgcatcgggcatt
caccaggatggcgtgttgaaagcgcgcgatacctacgaaatcatgcgcgccgaagacgta
ggctgggcaacgaacaagatcgtgctcggcaagctgtcgggccgcaacgcgttcaagcag
cgcctcgaagacctgggcgtgacgctggagtcggaaacggacgtgaacgcagcgttcgtg
cgcttcaaggaactcgccgaccgcaagtcggaaatcttcgacgaagacatcatggcgatc
gtctccgaagagtcggcggaaatgcaggcgaaggaaacgttccgcttcgtgtcgctggct
cagcgttcggaaacgggtgagcagccgcatgcacgcgtggtgtttgctgtcgatggcatc
gaagtgcacggcgagtcgcgtggtaacggtccggtggatgcgacgcttcacgcgatcgaa
tcgaaagtgacgagcggcgccgagctggtgctgtattcggttaacgccattaccacgggc
acgcaggctcagggcgaagtgaccgtgcgcttgtcgaagagcggccggattgtcaatggc
gtgggcacggacccggacattgtggcggcatcggcgaaagcgtatcttgccgcgctcaac
aagctccattcgaaagtcgaaaagctcaacccgcagctttcgtga
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