Burkholderia sp. JP2-270: DM992_05820
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Entry
DM992_05820 CDS
T07766
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
burk
Burkholderia sp. JP2-270
Pathway
burk00290
Valine, leucine and isoleucine biosynthesis
burk00620
Pyruvate metabolism
burk01100
Metabolic pathways
burk01110
Biosynthesis of secondary metabolites
burk01210
2-Oxocarboxylic acid metabolism
burk01230
Biosynthesis of amino acids
Module
burk_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
burk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DM992_05820 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DM992_05820 (leuA)
Enzymes [BR:
burk01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DM992_05820 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
BP74_N
Motif
Other DBs
NCBI-ProteinID:
AWU99126
UniProt:
A0A2U9SKB2
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All DBs
Position
1:complement(1213259..1214908)
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AA seq
549 aa
AA seq
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MKRNPQDKYRPFEPVRINGRRWPTRTIERAPVWMSTDLRDGNQSLIEPMSIEQKLEFFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIDDKRIPDDVTIEVLVQSREDLIARTFDALEGV
PRAIVHLYNAVCPSFRRIVFGMSKNDVKALAVDGTRIIKEHAAARPDTHWTFQYSPETFS
MTELTFAREICDAVAQTWRPTRDRKMIVNLPATVEAASPNVFADQIEWMDRNLAYRDSIV
LSVHPHNDRGTAVAAAELALLAGADRIEGCLFGNGERTGNVDLVTLALNLYTQGIDPGLD
FSDIDAVRRVVERCNQISVHPRHPYAGDLVFTAFSGSHQDAIRKGFAQQRPDAVWEVPYL
PIDPADLGRSYDAVIRVNSQSGKGGATFLLERGMGFTPTRRVQIEFSHAVQTLADASGEE
VTGDAICALFAREFFETDGPAARHGSGARWQNREIAAAPAAADATPEDAVRHLAAAFAAA
AGAAIDIASYEHARTTDGRIAVSVGCRVGDAPLRHGVGLHADAASAALDAIVSAINRSAW
YCTDRRAAA
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgcaatccgcaagacaagtaccgtccgttcgagcccgtccgcatcaatggccgc
cgctggccgacccgcaccatcgagcgcgcgcccgtctggatgagcaccgacctgcgcgac
ggcaaccagtcgctgatcgagccgatgagcatcgagcagaagctcgagttcttcgagatg
ctggtcgcgatcggtttcaaggagatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgtccgcaagctgatcgacgacaagcggattcccgacgacgtgacgatcgag
gtgctcgtgcagtcgcgcgaagacctgatcgcgcgcacgttcgacgcgctcgaaggcgtg
ccgcgcgcgatcgtgcacctgtacaacgcggtgtgcccgtcgttccgccgcatcgtgttc
ggaatgtcgaagaacgacgtgaaggcgctcgcggtcgacggcacgcgcatcatcaaggaa
cacgccgccgcgcgccccgacacgcactggaccttccagtactcgccggaaaccttcagc
atgaccgagctgacgttcgcgcgcgagatctgcgatgcggtcgcgcaaacctggcggccg
acccgcgaccgcaagatgatcgtcaacctgccggccaccgtcgaggccgcgagcccgaac
gtgttcgccgaccagatcgaatggatggaccgcaacctcgcgtatcgcgacagcatcgta
ctgtccgtgcatccgcacaacgatcgcggcaccgcggtcgcggcggccgaactcgcgctg
ctcgcgggcgccgatcgcatcgagggctgcctgttcggcaacggcgagcgcaccggcaac
gtcgatctcgtcacgctcgcgctgaacctgtacacgcagggcatcgacccgggcctcgat
ttctccgacatcgatgcggtgcgccgcgtcgtcgaacgctgcaaccagatttccgtgcat
ccgcgccatccgtacgcgggcgacctcgtgttcaccgcgttctcgggctcgcaccaggac
gcgatccgcaagggtttcgcgcagcagcgccccgacgcggtctgggaagtgccgtacctg
ccgatcgacccggccgacctcggccgcagctatgacgcggtgatccgcgtgaacagccag
tccggcaagggcggcgcgacgttcctgctcgaacgcgggatgggcttcacgccgacgcgc
cgcgtgcagatcgaattcagccacgcggtacagacgctcgccgacgcgtccggcgaggaa
gtgacgggcgacgcgatctgcgcactgttcgcccgcgaattcttcgagaccgacggcccg
gccgcgcgccatggcagcggtgcgcgctggcagaaccgcgagatcgcggcagcgccggca
gcggccgacgcgacgcccgaagacgccgtgcgacatttggccgcggcattcgcggcggcc
gccggcgccgcgatcgacatcgcatcgtacgaacacgcgcgcacgacggacggccggatc
gcggtatcggtcggctgccgggtcggcgatgcgccgctgcgccacggcgtcggcctgcac
gccgatgcggcgagcgccgcgctcgatgcaatcgtcagcgcaatcaaccgttcggcatgg
tattgcacggaccggcgcgcggcagcctga
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