KEGG   Burkholderia sp. JP2-270: DM992_05820
Entry
DM992_05820       CDS       T07766                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
burk  Burkholderia sp. JP2-270
Pathway
burk00290  Valine, leucine and isoleucine biosynthesis
burk00620  Pyruvate metabolism
burk01100  Metabolic pathways
burk01110  Biosynthesis of secondary metabolites
burk01210  2-Oxocarboxylic acid metabolism
burk01230  Biosynthesis of amino acids
Module
burk_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:burk00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    DM992_05820 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    DM992_05820 (leuA)
Enzymes [BR:burk01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     DM992_05820 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer BP74_N
Other DBs
NCBI-ProteinID: AWU99126
UniProt: A0A2U9SKB2
LinkDB
Position
1:complement(1213259..1214908)
AA seq 549 aa
MKRNPQDKYRPFEPVRINGRRWPTRTIERAPVWMSTDLRDGNQSLIEPMSIEQKLEFFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIDDKRIPDDVTIEVLVQSREDLIARTFDALEGV
PRAIVHLYNAVCPSFRRIVFGMSKNDVKALAVDGTRIIKEHAAARPDTHWTFQYSPETFS
MTELTFAREICDAVAQTWRPTRDRKMIVNLPATVEAASPNVFADQIEWMDRNLAYRDSIV
LSVHPHNDRGTAVAAAELALLAGADRIEGCLFGNGERTGNVDLVTLALNLYTQGIDPGLD
FSDIDAVRRVVERCNQISVHPRHPYAGDLVFTAFSGSHQDAIRKGFAQQRPDAVWEVPYL
PIDPADLGRSYDAVIRVNSQSGKGGATFLLERGMGFTPTRRVQIEFSHAVQTLADASGEE
VTGDAICALFAREFFETDGPAARHGSGARWQNREIAAAPAAADATPEDAVRHLAAAFAAA
AGAAIDIASYEHARTTDGRIAVSVGCRVGDAPLRHGVGLHADAASAALDAIVSAINRSAW
YCTDRRAAA
NT seq 1650 nt   +upstreamnt  +downstreamnt
atgaagcgcaatccgcaagacaagtaccgtccgttcgagcccgtccgcatcaatggccgc
cgctggccgacccgcaccatcgagcgcgcgcccgtctggatgagcaccgacctgcgcgac
ggcaaccagtcgctgatcgagccgatgagcatcgagcagaagctcgagttcttcgagatg
ctggtcgcgatcggtttcaaggagatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgtccgcaagctgatcgacgacaagcggattcccgacgacgtgacgatcgag
gtgctcgtgcagtcgcgcgaagacctgatcgcgcgcacgttcgacgcgctcgaaggcgtg
ccgcgcgcgatcgtgcacctgtacaacgcggtgtgcccgtcgttccgccgcatcgtgttc
ggaatgtcgaagaacgacgtgaaggcgctcgcggtcgacggcacgcgcatcatcaaggaa
cacgccgccgcgcgccccgacacgcactggaccttccagtactcgccggaaaccttcagc
atgaccgagctgacgttcgcgcgcgagatctgcgatgcggtcgcgcaaacctggcggccg
acccgcgaccgcaagatgatcgtcaacctgccggccaccgtcgaggccgcgagcccgaac
gtgttcgccgaccagatcgaatggatggaccgcaacctcgcgtatcgcgacagcatcgta
ctgtccgtgcatccgcacaacgatcgcggcaccgcggtcgcggcggccgaactcgcgctg
ctcgcgggcgccgatcgcatcgagggctgcctgttcggcaacggcgagcgcaccggcaac
gtcgatctcgtcacgctcgcgctgaacctgtacacgcagggcatcgacccgggcctcgat
ttctccgacatcgatgcggtgcgccgcgtcgtcgaacgctgcaaccagatttccgtgcat
ccgcgccatccgtacgcgggcgacctcgtgttcaccgcgttctcgggctcgcaccaggac
gcgatccgcaagggtttcgcgcagcagcgccccgacgcggtctgggaagtgccgtacctg
ccgatcgacccggccgacctcggccgcagctatgacgcggtgatccgcgtgaacagccag
tccggcaagggcggcgcgacgttcctgctcgaacgcgggatgggcttcacgccgacgcgc
cgcgtgcagatcgaattcagccacgcggtacagacgctcgccgacgcgtccggcgaggaa
gtgacgggcgacgcgatctgcgcactgttcgcccgcgaattcttcgagaccgacggcccg
gccgcgcgccatggcagcggtgcgcgctggcagaaccgcgagatcgcggcagcgccggca
gcggccgacgcgacgcccgaagacgccgtgcgacatttggccgcggcattcgcggcggcc
gccggcgccgcgatcgacatcgcatcgtacgaacacgcgcgcacgacggacggccggatc
gcggtatcggtcggctgccgggtcggcgatgcgccgctgcgccacggcgtcggcctgcac
gccgatgcggcgagcgccgcgctcgatgcaatcgtcagcgcaatcaaccgttcggcatgg
tattgcacggaccggcgcgcggcagcctga

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