Burkholderia sp. JP2-270: DM992_27175
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Entry
DM992_27175 CDS
T07766
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
burk
Burkholderia sp. JP2-270
Pathway
burk00290
Valine, leucine and isoleucine biosynthesis
burk00620
Pyruvate metabolism
burk01100
Metabolic pathways
burk01110
Biosynthesis of secondary metabolites
burk01210
2-Oxocarboxylic acid metabolism
burk01230
Biosynthesis of amino acids
Module
burk_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
burk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DM992_27175 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DM992_27175 (leuA)
Enzymes [BR:
burk01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DM992_27175 (leuA)
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Paralog
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
MOR2-PAG1_C
Motif
Other DBs
NCBI-ProteinID:
AWV03015
UniProt:
A0A2U9SV39
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All DBs
Position
2:2030496..2032208
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AA seq
570 aa
AA seq
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MMLKNPATKYRPFTPVNLPNRTWPSRTITHAPIWMSTDLRDGNQALFEPMDAARKMRMFK
TLVAIGFKEIEVAFPSASETDFNFVRELIEGGHIPDDVTIEVLTQARDDLIERTFESLRG
AKRAIVHLYNATAPEFRKIVFGLDRDGVKQLAVNAARTIKRCADAATDTQFTLQYSPETF
TATELDFAKEVCDAVFDVWQPTPEHKAIVNLPATVEVGTPNFYADQIEWMHRNLARRDSL
ILSVHPHNDRGTAVAAAELAVMAGADRIEGCLFGNGERTGNVDLVTLALNLYTQGVDPGL
DFSQINEVARTAEECTQLPIHPRHPYVGDLVFTAFSGSHQDAIKKGFAVQRADAVWEMPY
LPIDPSDLGRTYDSIIRVNSQSGKGGIAYLLEQGYGVALPRRLQVDFSAAVQRLTDDSGH
EVTSAQIWSLFQQEYVEGDAPLRYVGHELSERDGRETIVLTADVHGERRVLRGEGNGPLD
ALMHALRTPLRIQHYEERALSQGADAKAIAIAELAGSSVRGSAFGVGIDANLTTASIRAV
IGGVNRAYARADEAAQATFFGAQPAVKAVA
NT seq
1713 nt
NT seq
+upstream
nt +downstream
nt
atgatgctgaagaaccccgcaacgaagtaccggccgttcacgcccgtcaacctgccgaac
cgcacgtggccgtcgcgcacgatcacgcacgcgccgatctggatgagcaccgacctgcgc
gacggcaaccaggcgctgttcgagccgatggatgcggcgcgcaagatgcggatgttcaag
acgctcgtcgcgatcggtttcaaggagatcgaggtggcgttcccgtcggcgtccgagacc
gatttcaacttcgtgcgcgaactgatcgaaggcggccacattcccgacgacgtgacgatc
gaggtgctcacgcaggcgcgcgacgacctgatcgagcgcaccttcgaatcgctgcgcggc
gcgaagcgcgcgatcgtacacctgtacaacgcgaccgcgccggaattccgcaagatcgtg
ttcggcctcgaccgcgacggcgtgaagcaactcgcggtgaacgcggcgcgcacgatcaag
cgctgcgccgatgccgcgaccgacacgcagtttacgctgcagtacagcccggaaacgttt
acggcgaccgagctcgacttcgcgaaggaagtctgcgacgccgtattcgacgtatggcag
ccgacgcccgagcacaaggcgatcgtgaacctgccggcgaccgtcgaagtcggcacgccg
aacttctatgcggaccagatcgaatggatgcaccgcaacctcgcgcgtcgcgattcgctg
atcctgtccgtgcatccgcacaacgaccgcggtaccgcggtcgcggcggccgaactcgcg
gtgatggccggcgccgaccggatcgagggctgcctgttcggcaacggcgagcgcaccggc
aacgtcgatctcgtcacgctcgcgctgaacctgtacacgcagggcgtcgatccgggcctc
gatttctcgcagatcaacgaagtcgcgcgcaccgccgaggaatgcacgcagttgccgatc
catccgcgtcatccgtatgtcggcgacctcgtgttcaccgcgttctccggctcgcaccag
gatgcgatcaagaagggcttcgcggtgcagcgcgccgacgccgtgtgggaaatgccgtat
ctgccgatcgatccgagcgacctcggccgcacgtacgattcgatcattcgcgtgaacagc
cagtcgggcaagggcggcatcgcgtacctgctcgaacagggttatggcgtcgcgctgccg
cgtcgcctgcaggtcgacttcagcgcggccgtgcagcgcctgaccgacgacagcgggcac
gaggtgacgagcgctcagatctggtcgctgttccagcaggaatacgtggagggcgacgcg
ccgctgcgttatgtcggccatgaactgtcggagcgcgacggccgcgagacgatcgtgctg
accgccgacgtgcacggcgagcgccgcgtgctgcgcggcgaaggcaacggcccgctcgat
gcgctgatgcatgcgctgcgcacgccgctgcgaatccagcactacgaggaacgcgcgctg
tcgcagggtgccgatgcgaaggcgatcgcgatcgcggaactggccggctcgagcgtgcgc
ggcagcgcgttcggcgtgggcatcgacgcgaacctgacgaccgcgtcgatccgcgcggtg
atcggcggcgtcaaccgcgcgtatgcgcgggcggacgaagcggcgcaggcgacgttcttt
ggcgcgcagccggcggtgaaggccgtcgcgtaa
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