Burkholderia sp. THE68: BTHE68_12330
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Entry
BTHE68_12330 CDS
T10528
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
burt Burkholderia sp. THE68
Pathway
burt00230
Purine metabolism
burt01100
Metabolic pathways
burt01110
Biosynthesis of secondary metabolites
Module
burt_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
Enzymes [BR:
burt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
BTHE68_12330 (purL)
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NCBI-ProteinID:
BBU27499
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Position
1:1314770..1318807
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AA seq
1345 aa
AA seq
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MAHFSCFPGASALSDFRQTRLLETLARIDANIVGVRGQFLHFVNASEPLTDDDNSRIEAL
MHYGAPFEESKERGHVESFMVVPRFGTVSPWASKATDIAHHCGLDKVRRIERGVEYSVIM
KSGFLGGKKALSDEARAAVADALHDRMTESVAASREQALHLFDELPARPLQTVDIIGAGH
KALEAANAELGLALADDEIDYLVNAFEGLKRNPTDVELMMFAQANSEHCRHKIFNGEWTI
DGDKQDMSLFQMIRNTEKLNHEGTIVAYSDNSAIMRGGVAERWFPRGTDEQYRRHVELTH
TLMKVETHNHPTAISPFAGAATGSGGEIRDEGATGRGARPKAGLAGFTVSNLDLPDAREK
WENARDSAVPLASRNPADQHEPYGKPERIASPLQIMIDGPIGAAAFNNEFGRPNLGGYFR
TYEQNVAGRVRGYHKPIMIAGGIGNISDQHTHKNDLPAGTLLIQIGGPGMRIGMGGGAAS
SMATGANTAELDFDSVQRGNPEIQRRAQEVINTCWQMGEGNPILSIHDVGAGGISNAFPE
LVDGAGKGARFDLRKVQLEESGLSPREIWSNEAQERYVLAISPADLPAFQAICERERCPV
AVVGVATEERQLKLIDEANDGQEPVDMPMDVLLGKPPKMHRDVKRESAQFTPVDVTGLPL
SEVAVDVLKHPTVASKSFLITIGDRSVGGTTARDQFVGPWQVPVADCAVTTMDYAGYRGE
AMTMAERTPLAVIDAPASGRMAVGEAVTNIASAPIESLNKLKLSANWMAACGSEGEDAAL
YDTVKAIGMELCPALGISIPVGKDSLSMRTKWQDARGGAREVVSPVSLIISAFAPVEDVR
RHLTPQLVNDTSTVLIAIDLGRGRNRMGGSILAQVTQQVGDTVPDVDDPEDLKRFFTAIQ
ALNADGKLLAYHDRSDGGLWATVCEMAFAGHVGVSLNIDMLTLDAEHESDYGDAKDWAKQ
TSGRREDRTIRALFSEELGAVVQVRASERDAVLAALREHGLSACSHVIGKPNESGAIEIY
RDAKKIFDAPRVELHRAWSEVSWRIARLRDNPACADAEYDALLDAADPGIAPVLTFDLAE
DVAAPFVSTQARPRVAILREQGVNSHLETAYAFDRAGFDAHDVHMSDLLEGRATLADFAG
AVACGGFSYGDVLGAGEGWAKTIRFNPRLADMFAAFFGRADTFALGICNGCQMMSSLASI
IPGAENWPKFTRNKSEQFEARFSLVEVQSSPSMFFAGMEGSRIPVAVAHGEGFADFSQQG
DQAKALVAMRYVDHRGNATEQYPFNPNGSPQGITSVTTPDGRFTVLMPHMERVHRNVQMS
WTPDDWTTDGSPWLRVFQNARRFLG
NT seq
4038 nt
NT seq
+upstream
nt +downstream
nt
atggcccacttctcgtgtttccccggcgcttcggccctctccgatttccgtcagacccgc
ctcctcgaaacgctcgcccgcatcgacgcgaatatcgtcggcgtgcgcggccagttcctg
catttcgtcaacgcgtccgagccgctcacggacgatgacaacagccgcatcgaggcgctg
atgcactacggcgcgccgttcgaggaatcgaaggaacgcggccacgtcgagagcttcatg
gtggtgccgcgcttcggcacggtttcgccgtgggcgagcaaggcgaccgacatcgcgcat
cattgcgggctcgacaaggtgcggcgcatcgagcgcggcgtcgagtactcggtcatcatg
aaaagcggctttctcggcggcaagaaggcgctgtccgacgaagcccgcgcggccgtcgcg
gatgcgctgcatgaccgcatgacggaaagcgtcgcggcatcgcgcgaacaggcgctgcat
ctgttcgacgaactgcccgccaggccgctgcagacagtcgatatcatcggcgcgggacac
aaggcgctcgaggctgcgaacgcggaactcggcctcgcgctcgccgacgacgaaatcgac
tatctggtgaacgcgttcgaaggcctgaagcgcaatccgaccgacgtcgagctgatgatg
ttcgcgcaagcgaacagcgagcattgccgccacaagatcttcaacggcgaatggaccatc
gatggcgacaagcaggacatgtcgctgttccagatgatccgcaatacggaaaagctgaat
cacgaaggcacgatcgtcgcgtattcggacaattcggcgatcatgcgtggcggcgtcgcc
gagcgctggttcccgcgcggcacggacgagcagtatcggcgtcacgtcgaactgacgcat
acgctgatgaaggtcgagacgcacaatcacccgaccgcgatttccccgttcgcgggcgcg
gcgacgggttccggcggcgaaatccgcgacgaaggcgcgacgggccgtggcgcgcgtccg
aaggccggtctcgcgggcttcaccgtgtcgaacctcgatctgcccgacgcgcgcgaaaaa
tgggagaacgcgcgcgactccgccgtgccgctcgcgtcgcgcaatccggccgaccagcac
gagccgtatggcaagcccgagcgcatcgcgtcgccgttgcagatcatgattgacgggccg
atcggcgccgccgcgttcaacaacgaattcggccggccgaatctgggcggctatttccgc
acctacgagcagaacgtcgcaggccgcgtgcgcggctatcacaagccgatcatgatcgcg
ggcggcatcggcaatatttcggatcagcacacgcacaagaacgatctgccggcgggcacg
ctgctgatccagatcggcgggccgggcatgcgtatcggcatgggcggcggcgcggcatcg
tcgatggcgaccggcgcgaacaccgccgaactcgacttcgactcggtccagcgcggcaac
ccggaaatccagcgccgcgcgcaggaagtcatcaacacctgctggcagatgggcgagggc
aatccgatcctgtcgatccacgacgtcggcgcgggcggcatctcgaacgcgttcccggag
ctcgtcgatggcgcgggcaagggcgcgcgcttcgatctgcgcaaggtgcaactggaagaa
agcggtctgtcgccgcgtgaaatctggtcgaacgaagcgcaggagcgctacgtgctggcc
atttcgcccgccgatctgcccgcgttccaggccatctgcgagcgcgaacgctgcccggtg
gccgtcgtcggcgtggcgacggaagagcgtcaactgaaactgatcgacgaggccaacgac
ggccaggaacccgtcgacatgccgatggacgtgctgctcggcaagccgcccaagatgcac
cgcgacgtgaagcgcgagagcgcgcaattcacgcccgtcgacgtgacggggctgccgctg
tccgaagtcgccgtcgacgtgctgaagcatccgacggtcgcgagcaagtcgtttctcatc
accatcggcgaccgctcggtcggcggcacgaccgcgcgcgaccagttcgtcggcccgtgg
caggtgcccgtcgccgattgcgccgtgacgacgatggattacgcgggctaccgcggcgaa
gcgatgacgatggccgagcgcacgccgctcgccgtcatcgacgcgcccgcatcgggccgc
atggcggtgggcgaggcggtgacgaacatcgcgtcggcgccgatcgagtcgttgaacaag
ctgaagctgtcggcgaactggatggccgcgtgcggcagcgagggcgaagatgccgcgctt
tacgacaccgtgaaggccatcggcatggagctgtgtccggcgctcggcatcagcattccg
gtcggcaaggattcgctgtcgatgcgcacgaagtggcaggacgcgcgcggcggtgcgcgc
gaggtcgtgtcgccggtgtcgctgatcatttcggcgttcgcgccggtggaagacgtgcgc
cgtcatctgacgccccagctcgtcaacgacaccagcacggtgctgatcgcgatcgatctg
ggacgcggccgcaaccgcatgggcggcagcattctcgcgcaagtgacgcagcaggtcggc
gacacggtgcccgatgtcgacgatcccgaagacctcaagcgcttcttcaccgcgatccag
gcgctcaacgccgatggcaaactgctcgcctaccacgaccgctccgacggcggcctgtgg
gcgaccgtttgcgagatggcgttcgcgggtcacgtgggtgtgtcgctgaacatcgacatg
ctgacgctcgacgccgaacacgaatccgactacggcgacgcgaaggactgggccaagcag
accagcggccgccgcgaagaccgtacgatccgcgcgctgttctccgaagaactcggcgcg
gtggtgcaggtgcgcgcatcggagcgtgacgcggtgctggccgcgttgcgcgaacacggt
ctgtcggcgtgctcgcatgtgatcggcaagccgaacgagagcggcgcgatcgagatttat
cgcgatgcgaagaagattttcgatgcaccgcgtgtcgagttgcatcgcgcgtggagcgag
gtgagctggcgcatcgcgcgtctgcgcgacaacccggcctgcgccgatgccgaatacgac
gcgctgctcgatgcggccgatcccggcatcgcgccggtgctgaccttcgatctggccgaa
gacgtcgccgcgcccttcgtttcgacgcaggcgcggccacgcgtcgcgattctgcgcgag
cagggcgtgaactcgcatctggagacggcctatgcattcgaccgcgccggcttcgacgcg
cacgatgtccacatgagcgacctgctcgaaggccgcgcgacgctcgccgatttcgcgggc
gcggttgcgtgcggcggcttctcttacggcgatgtgctgggcgcgggcgagggctgggcc
aagacgatccgtttcaacccgcgtcttgccgacatgttcgctgcgttcttcggtcgcgcg
gacaccttcgcgctcggcatctgcaacggctgccagatgatgtcgagcctggcgtcgatc
atccccggcgcggagaactggccgaagttcacgcgcaacaagtcggagcagttcgaggcg
cgtttctcgctcgtcgaagtgcagagctcgccgtcgatgttcttcgcgggtatggaaggt
tcgcgcattccggtcgcggtcgcgcatggcgaaggctttgctgacttctcgcagcagggt
gatcaggcgaaggcgctcgtcgcgatgcggtacgtcgatcatcgcggcaatgcgacggag
cagtatccgttcaacccgaacggctcgccgcagggcatcacctcggtgacgacgcccgat
gggcgctttacggtgctgatgccgcatatggagcgtgtgcatcgtaatgtgcagatgagc
tggacgcccgatgactggaccactgacggaagcccgtggttgcgggtgtttcagaacgcg
cggcggttcctcggttga
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