Burkholderia sp. THE68: BTHE68_27770
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Entry
BTHE68_27770 CDS
T10528
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
burt Burkholderia sp. THE68
Pathway
burt00790
Folate biosynthesis
burt01100
Metabolic pathways
burt01240
Biosynthesis of cofactors
Module
burt_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
burt00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
BTHE68_27770 (folC)
Enzymes [BR:
burt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
BTHE68_27770 (folC)
6.3.2.17 tetrahydrofolate synthase
BTHE68_27770 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BBU29043
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Position
2:151962..153272
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AA seq
436 aa
AA seq
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MNTFPTLDAWLAHLEAAHPVGIDMGLARIGKVKDALGLHFDCPVITVGGTNGKGSTCAII
ETILLRAGYRVGCHTSPHLLSFNERARIDGAEASDAELLEHFEAVEKARASLAEPVSLTY
FEFTTLAILHLFASRGLDAVVLEVGLGGRLDAVNIVDTDCAVITSIDIDHTDYLGDTREK
IGFEKAGIFRSNTPAVCGDPSPPQSLIDHAEAVGADLWLVGRDFRYEAQPGNERQQWSYI
GREQRRSALAYPALRGANQLINTSAALAALEALRARLPVSAQDIRLGLANVELPGRFQVL
PGKPQIILDVAHNPHAAAVLSQNLGNMGYFPYTYAVFGAMRDKDIEGVVNQLKGEIDHWN
VTALPTPRAASAEQLEHALREAGVNDGPDSSVFRFETPAAAFQDALGRASENDRILVFGS
FYTVAGVMAYRKSQHH
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgaacactttccccactctcgacgcctggctcgcccatctggaagcggcgcatccggtc
ggcatcgacatgggcctcgcgcgcatcggcaaggtaaaggacgcgctcggcctgcatttc
gattgtccggtcattaccgtcggcggcacgaatggcaagggctcgacgtgcgcgatcatc
gaaacgattctgctgcgtgcgggatatcgcgtcggctgccatacgtcgccgcatctgctg
tcgttcaatgagcgtgcgcgtatcgatggcgccgaagccagcgacgccgagctgctcgag
catttcgaggcggtggaaaaggcgcgcgcgagcctcgccgagccggtctctctgacctac
ttcgaattcacgacgcttgcgatcctgcatctgttcgcctcgcgcgggctcgacgcggtg
gttctcgaagtggggctgggcgggcgtctggacgcggtgaatatcgtcgatacggactgc
gcggtgatcacgagcatcgatatcgaccatacggactatctcggcgatacgcgcgagaaa
atcggtttcgagaaagcggggattttccggtcgaacacgcccgccgtgtgcggcgatcct
tcgccgccgcagagtctcatcgaccacgccgaggcggtcggcgcggacctgtggctcgtc
ggacgcgatttccgttacgaagcgcagccgggcaacgagcgccagcaatggagctatatc
gggcgtgagcagcggcgctcggccctggcctatccggcgctgcgcggcgcgaatcaactg
atcaatacctcggcggcgctggcggcgcttgaagcgctgcgcgcgcgcctgcctgtatcg
gcgcaggacattcgtctaggcctcgccaatgtcgagttgccgggccggtttcaggtgctg
ccgggcaagccgcagatcattctcgatgtagcgcacaatccgcacgctgccgccgttttg
tcgcaaaatctcggcaacatgggctattttccgtacacgtacgcagtgtttggcgcaatg
cgcgacaaggacattgaaggcgtcgtgaatcagttgaagggcgagatcgatcactggaac
gtcaccgcactgccgacgccgcgcgctgcctcggcggagcaactggagcacgcattgcgc
gaggccggtgtcaacgatggccccgacagcagcgttttccggtttgaaacgccggccgca
gcttttcaagatgctttaggccgtgcctccgaaaatgatagaatcttggtcttcggcagt
ttctacacggtagcaggcgtcatggcctaccgtaagtcgcagcatcactga
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