Beta vulgaris (sugar beet): 104907046 Help Entry 104907046         CDS       T03548                                  Name (RefSeq) auxin transport protein BIG   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism bvg  Beta vulgaris (sugar beet) Brite KEGG Orthology (KO) [BR:bvg00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:bvg04121]     104907046 Enzymes [BR:bvg01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      104907046 Ubiquitin system [BR:bvg04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     104907046 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 UBR4 ZZ zf-UBR Motif Other DBs NCBI-GeneID:  104907046 NCBI-ProteinID:  XP_010694206 LinkDB All DBs Position 2:5152262..5175333 Genome browser AA seq 5090 aa AA seqDB search MAEELAKLVEAVSSTQSDLSLRLRTSSSLKLGLHHFYSILNYGVQAIDGENQSDFDDNAK KLGLQCWSISQIHSVCSLALLIATATRSLSVEHVEPEVVATLHESMEFALCCLEKSNISD DLSLQNLAVKLLEMGLLGQIDNESDSSQSCIASSLVDGLPPVSFREGGSLFEKHTQWNTV GEQPVDQLVMRLTSDMQAGNATQSTTDSIYTQDYNKLVSSTQHWAVLHLGCIRRLILFCT ELVQLPEAFDVKLADLSFCRKLSLSLNILKLLRNLARSVPYVELDSELLQSIAAFADVFP GMFRPGIEFISSNIAFENYYDSAVLNILEEFLHLVQILSCGKRVFQNVRACVLASILGIL DLSVWRYNKSVSNLKPPLVYFPRCVIYVVKLIGDVKNQGNEKHVVRDLGADLSLGISDPD GRGVCQVRSGSILLSKNYTVEELLEIIFPKSMQWVDNLIHLLCFLHNEGVKLQPKLEKSS SCLKSSSIPELENTNCHDDEALFGDLFSEGGRSVGSNDGYEQVPSVNPLTGSYEMIIQAA AEIFIFLKSCVCSPEWCAPVYEDACKKLGRDHIDSLLAMLGSQICYYDGFDGGPGVHEQR RIEQIQEICFEMLHGLLKHHALSDVLEEHLVLQILKVENGSFAYNDQTLVLVAQTLVCRV GSAGSHLRNKLYRQFVNFIVEKEKDVRSNCPILRELVISLPNVFHMEIILLAFHLSSESE KVALADLIFSHLKTFAASSQMLSSSQLSCWALIVSRLIVIFRHMLLNFRACPTSLLMDFR LKLNVARLTGCQNRQPNDSVISWSSIVVGKVMSSFIKEESLLGNLLNHLIDFESGPARLV SCDAADASPFGSWNDIYTVFSPLVGLWRGKKAATIEDLVLERYMFLLCLDMPAAGLSVNR LSSIWSANCDLDTSNIEHFVLFSHLLLGHYDLVNSHVDPVDMISRLLQHLCSVSMPDDIL EFGWDWLRSGQWLSVVLSFLYTGFGSYCFKNSVPAVDFIWTENASDSEFVAFAEGFIGLM LETNKVPVILKSLSALLTKYISVYQKAFLFTISENQSHAQNYSPLLLLKHTEFDECMTEE ILVKNGLVHVGLESVYDLITKIDSVTTKRASHLLGVISSECMLHGFPTHPQASSGVLISS ILSIRGIICLLDLLIKISGTRGGISLETDVLHEILDSVMSVKYDKVFKNLGEKCGDICRG CAGAEGPDYSSLFLMKQIEGFLSDINLSGSADHVKVEQLVVKAVDVMDALQRDLIGVNVL RFYLGAEDVSQQDVELYGSQRGDLLVLIDSLESCHSELVNAKVLNFFIDVLSGDLGPYVK QRIQKKFLGIDISCLSKWFEKRLLSFSTEDSANLTSAVTCAKGSLMSLRESTMSFILCLV SPDDPLSRELYSHLFNALLVSLETAFKVYDIHTAKSYFGFVTQLLRDEPSMRLLLQSSLS LMEKLAVEEHQLQGLKFLFSFFEVILTDSGSFASIPTKSTAKSLSGSSRGLGSISSRTGG SRKSTDTLILSANQDGSSVSFEYDAASIDEDEDDGTSDGEVASIDKDDEEDSSSERALAS KVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRVVYSRSSRFFCDCGAG GVRGSTCQCLKPRKFTGSNVAPAKGPGSFQSLLPFTEDGDQLPDSDSDPDEDASIEADNS LRLSVPNDIQGAIPRLYEELDLEAQVLKICNLLLPSITRRRDGDLSRDKNLILGVEKVLS YGSDLLQLKKAYKSGSLDLKIKADYSNAKELRSLLASGALMKSLLSVSGRGRLAVGEGDK VAIFDVGQLIGQATVAPVTADKTNVKPLSKNVVRFEIVHLAFNPLAENYLAVAGYDDCQV FTVTPRGEVTDRLAIELALQGAYIRRVDWVPGSQVQLMVVTNRFVKIYDLSQDNISPLHY FTLADQMITDAVLSVASQGTVYLIVLSELGNLFKLQLSTEVNAGTKQLNEKVDISTRDVH VKGSSLYFSSTYKLLFVSYQDGSTFIGRLNSDATSLTEISAVYEDEQDDKRRPAGLHHWK ELMPGSGLFVCFSSWRSNAALAVSLGAHEIFSQNIRHAVGSNSPVVGATAYKPLSKDKIH SLILHDDGSLQIFSHVQAAGDSGSNATSEKVKKLGPNILSNKAYAGVNPEFPLDFFEKTV CITADVKLGGDAVRNGDSEGAKQSLTSEDGFLESPSSSGFKITVSNSNPDIVMVGIRVHV GNTSANHIPSDITIFQRVIKLDEGMRCWYDIPFTVAESLLADEEFTVSVGTTFNGSALPR IDSLEVYGRPKDEFGWKEKMDAVLDMESRVLGSNSWAITSRKKIRSMQSAPPEEEVLADG LKLLSRLYLLCKPQGCSKVEDMKPELSVLKCKQLLETIFESDGEPLLQSSACRILQAAYP KREIYYQVKDSMRLLGVVKSAALILSRLGVGGSTSAWIIEEFTAQMHAVSKIALHRRSNL AAFLEMNGSQVVDGLMQVLWGILEIEQPDTQTMNNIVISSVELIYCYAECLALHGKEAGG HSVAAAVVLLKKLLFSPNEAVQTASSLAISSRLLQVPFPKQTMLATDDAADNATSASAHV DTVTASGGNAQVMMEEETVTSSVQYCCDGCSTVPILRRRWHCTVCPDFDLCEACYEVVDA DRLPPPHSRDHLMTAIPIEVENLGGEGTEIHFPSGELSVSGILPTSSNSNVQNSTPSIHV LEPNELEDFSPSVLDPISISESKRAVNSLLLSELLDQLRGWMLTTSGVRAIPVMQLFYRL SSAVGGPFIHSSNPESLDLEKLIKWFLDEINLKKPFVARSRSSCGEVTILVCMFFTLMLR NWHQPGSDGSVPKSGGSSDTLDRSYIQNPLSASFAAAVSSDNQDKNDFTMQLLRACNVLR QQSFVNYLMDILQQLVHVFKSTAGNLESSSSSHPGSGCGALLSVRRELPAGNFSPFFSDS YAKAHRVDIFADYHRLLLENTFRLVYSLVRPEKHEKSGEKEKVYKLSSSKDLKLEGYQDV LCSYINNPHTTFVRRYARRLFLHLCGSKSHYYSVRDSWQFSSEIKRLHKHVNKTGGFQNP VPYERSVKIIKCLCTMAEVAAARPRNWQKYCLRHAEVLPLLLKWIFYLGEESVIQTLKLL NLAFYTGKDMNHSSQKVESGDAAVGSNKSASQSQDTKKKKKGDDGTESGSEKSCLDMEVA VDIFTDKDGEVLRQFIDCFLLEWNSSAVRAEAKCVLHGIWQHGKQLFKENMLRVLFEKVK CLPMYGPNIAEYTELQTWLLGKVPDVSLKQLNAELLDKCLTSDVIQCFYETLHMQNELLA NHPNSRIYNTLSGLVEFDGYYLESEPCVSCSSPEVPYSRMKLESLKSETKFTDNRIIVKC TGSYTIQSVTMNVHDARKSKSVKVLNLYYNNRPVTDLSELKNNWSLWKRAKSCHLASNQT ELKVDFPIPITACNFMIELDSFYENLQASSMEPLQCPRCSRPVTDRHGICSNCHENAYQC RQCRNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFTFDNMENDEDMKRGLAAIESESE NAHRRYQQLLGFKKPLLKIVSSIGENDIDSQQKDSVQQMMVSLPGPSCKINRKIALLGVL YGEKCKAAFDSVSKSVQTLQGLRRVLMNYLHQKHCAQTTEPSRFVVSRTPSSCYGCATTF VVQCLEILQVLSKHPNSKRQLVASGILTELFENNIHQGPKSARSQARAVLCAFSEGDMNA VNQLNNLIQKKVLYCLEHHRSMDIAVATREEMLLLSEICSSTDEFWESRLRVVFQLLFTS IKVGSNHPAISEHVILPCLRIISQACTPPKADMLDKESSGKSQPSKDASNSDVTGTLGVP ANVSSSTSELVERNWNGSQKTQDIHLLSYSEWEKGASYLDFVRRQGKVSQAFRGPGHKSR PQRYDFLALKYGLRWKRRACARNNFASFELGSWVSGLILSACSQSIRSEMCMLVNLLCAQ SSSRRFRLLNLLMAWLPLTLSAAENAVEYFDLLFKMIEMEDARLFLTAGGCLSTICKLIT QEVNNIESLERSLHIDISQGFILHKLIELLGKFLEIPNIRARFMRDDLLSEVLEALIVIR GLVVQKTKLISDCNRLLKDLLDSLLQESSENKRLFIRACICGLQIHGDEKKGQISLFILE QLCNLICPSKPESVYFLILNKAHTQEEFIRGNMTKNPYSSAEVGPLMRDVKNKICHQLDM LGLIEDDYGMELLVAGNIISLDLSVAQVYEQVWKKANIQSSNTVANATMLAAGGTASTRD CPPMIVTYRLQGLDGEATEPMIKELDEDREESQDPEVEFAIAGAVREYGGMEIILGMIKR LRDDLKSNHEQLIVVLNLLMYCCKIRENRRALLRLGALSLLLETARRAFSVDAMEAAEGI LLIVEALTLEANESDNINITQSGLTITSEETGAGEQAKKIVLMFLERLSHTSGLKKSSKQ QRNTEMVARILPYLTYGEPSAMEALVQHFDPYLQNWTEFDRLQTQHEDDPKDDGIAQRAV NQRFAVENFVRVSESLKTSSCGERLKDIILEKGITGVAVGHLREIFAVAGHPGYKSMAEW TLGLKLPSVPLILSMLRGLSMGHLPTQNCINEGGILPLLHALEGVSGENEIGARAENLLD TLSDKEGNGDGFLGEKILNLRHATRDEMRRRALRKREELLQGLGMRQELSSDGGERIVVS RPNLEGFEDVEEEEDGLACMVCREGYSLRPNDLLGVYSYSKRVNLGAGTSGSARGECVYT TVSHFNIIHFQCHQEAKRADAALKNPKKEWEGATLRNNETLCNALFPIRGPAVPLGQYVR YVDQYWDNLNALGRADGSRLRLLMYDIVLMLARFATGASFSSDSKGGGKESNSKFLPFMI QMARHLLDQGSGSQRRSMARAISSYLTSSSDSRPSPSSPLQPSGGTEETVQFMMVSSLLT ESYEFWLQHRRAFIQRGIYHAYMQHAHSKSLPRGSSSTRSEQVTSGSDDLLPIIQPMLVY TGLIEQLQQFFKPKQSTVGASTDGEGTSKEGEGDDENGLESWEVVMKDKVLDMKEMVGFS KELLSWLDDMTSAGDLQEAFDVIGALADVLSGENKSCEEFVQAAINAGKN NT seq 15273 nt NT seq  +upstreamnt  +downstreamnt atggcggaagaactcgcgaaacttgtcgaagctgtatcatctactcaaagcgatctctct ttgagacttcgaacttccagttcactcaaattagggttgcatcacttctattctatcctc aattacggtgttcaagcgatcgatggcgaaaatcaatctgattttgatgataatgcgaag aagttagggcttcaatgttggagtatttctcagattcattctgtttgttctcttgcactt ttgattgctaccgccactcgatcgctttcagttgagcatgtggaacctgaggttgttgct actttgcatgaatcgatggagttcgctttgtgctgcttggagaaatcgaatattagtgat gacttgagcttgcagaatcttgcggtgaagttgctggaaatgggattattgggtcagatt gataatgaatctgattcatctcagtcttgcatagcaagttcccttgtagatggcttgcct cctgtctcttttagagagggaggttctttgtttgaaaagcacacccagtggaataccgta ggagaacaacctgttgatcagcttgttatgagattgacgtcagatatgcaagctggtaat gcgacacaatcgacaacagactccatctatacccaagattacaacaagttggtgtcctca actcagcattgggctgttcttcacttaggttgcatccgccggctcatcctattctgtaca gaacttgttcagcttccggaagcattcgatgttaaactggcagatttgagcttttgtcga aaactatctctttcattgaatattctgaagttactaagaaatcttgctaggagtgtccct tacgttgaattggactctgaattgctgcagagtattgctgcttttgctgacgtgtttcct ggcatgtttagaccgggaattgagttcataagtagcaatatagcgttcgaaaattactat gacagtgctgtactgaatatccttgaagaatttctacatttggtacaaatacttagctgc ggtaagagggtcttccaaaacgttagggcatgtgttctggcttctatacttggtattttg gatcttagtgtatggagatataacaagtcagtcagtaatttgaaacctcctttggtttac ttccctcgctgtgtaatttatgttgtgaaactcattggcgatgttaaaaatcaaggaaat gagaagcatgtggtgagggatttgggtgcagacctctccttgggtatatctgatcctgat ggcagaggtgtgtgtcaagttcgatctggcagtatactgttgtcgaagaattacacagtt gaggaactcttggaaatcatatttcctaaatcaatgcagtgggtggataatctgatacat cttctttgtttcttgcataatgagggagtgaaattgcagccaaaacttgagaaatcttct tcatgtttaaaatccagttccattcctgagttggaaaacactaattgccacgatgatgaa gccttatttggagatctcttttccgagggtggtcgctctgttggatcaaatgatggatat gagcaagtaccttctgttaatcccctcactggttcttatgaaatgataatacaagctgct gctgaaattttcatcttccttaagtcctgcgtatgttctccagaatggtgtgctcctgtg tatgaggatgcttgcaagaagcttggcagagatcatattgattctctgctggcgatgctt ggctctcaaatttgttactatgatgggtttgatggtgggcctggtgttcatgagcaaagg aggatagagcaaattcaagagatatgtttcgagatgttgcatggtctgcttaagcatcat gctctctctgatgtgctggaggagcaccttgtacttcaaatattgaaggttgaaaatggg tcttttgcttacaatgatcaaacccttgtattggtcgctcagacattagtctgtagagtg ggttcagctggcagccatttgagaaataaactttacaggcagtttgtgaattttatagtt gaaaaagaaaaagatgtacgctcaaattgtcccatactaagggaacttgtcatctctctt cctaatgtctttcacatggagattattcttttggccttccatctgtcttctgaaagtgaa aaggtggctctagcagacctcattttctctcatttaaagacctttgctgccagttcacag atgttgagcagttcgcaactatcttgctgggctctgatagtttcacgattgattgtaatt tttcgacatatgttgttgaattttcgtgcttgtccaacatcattgctcatggatttcaga ttgaagctgaatgtagcccgacttactggatgccagaatcgccaacccaatgattctgtg atatcttggtcctctattgtagtcgggaaggttatgagttcgtttattaaggaagagtct ctcctcggcaacctgcttaatcatcttattgattttgaatctggccctgcgaggctggtt agctgtgatgcagccgatgctagtccctttgggagttggaatgacatatatactgtcttt tcaccacttgtggggctatggaggggtaagaaggctgcaacaattgaagatttagttctc gagaggtacatgtttctgctttgcttggatatgcctgctgctgggttgtcagtgaaccgt ctgtcctccatttggagtgccaactgtgatcttgatacatcaaatattgagcattttgtt ctttttagccatttattgctgggacattatgatcttgtaaatagccatgtggaccctgtg gatatgatctcaaggttgcttcagcacttgtgctctgtttccatgcctgatgacattctg gagtttggttgggactggttaagaagtgggcagtggctttccgtggttctttctttcctt tatactggttttggaagctactgttttaagaattctgtcccagcagtcgactttatatgg acagaaaatgcatctgattcggagttcgttgcctttgctgaaggtttcatcggattgatg ttggaaactaataaagtccctgtgatactgaaaagtttgtctgcattattgactaaatat atcagtgtgtaccagaaggcctttttgttcaccattagtgagaaccagtcacatgcccag aattattctcctcttttgcttctcaaacacactgaatttgatgagtgcatgacggaggaa atcctggtgaagaatggtcttgttcatgtgggattggagtctgtttatgacctcattaca aagattgacagtgtaacaaccaagagggcttcccacttactgggtgttatatcctctgaa tgcatgcttcatggtttccccacacaccctcaagcctccagtggggtcctcatttcctct attctcagtatcagaggaataatttgtcttcttgatttgctaattaaaatcagtgggaca aggggaggaatttctttggagactgacgtgctccatgagattcttgactctgtgatgtca gtgaaatatgataaggtttttaaaaacttgggtgagaagtgtggagatatatgtcgtggg tgtgcaggtgcagaagggccagattatagttcattgtttctgatgaagcagattgaagga tttctttcggacatcaatcttagtgggagtgccgaccacgttaaggttgaacaattagtt gtcaaagctgttgatgtgatggacgctcttcagcgagatctcattggggtcaatgttctc agattttatcttggtgctgaagatgtttcccaacaggatgttgaactttatggttcacag cgtggtgatttgcttgttctgatcgactctctagaaagctgtcactctgaattagtcaat gccaaggttctcaatttctttattgatgttttgtcaggggacctgggcccttatgtcaaa caaagaattcaaaagaaatttcttggtatagatataagctgtctgtccaagtggtttgag aagagattgttgagtttctcgactgaagattctgctaatcttacatcagcagttacatgt gctaaaggaagtttaatgtccctcagagaatcaaccatgagcttcatcttgtgccttgta tctcctgatgacccgctttctagagaattatacagccatttgtttaatgctttgcttgtt tcgttggagacagcttttaaagtatatgatattcacactgcaaaatcttattttggtttt gtgactcaactcttaagagacgagccttcaatgagactactgctgcagagtagtctctct ttgatggagaagctcgctgttgaggagcatcagctgcagggattgaagttccttttcagt ttctttgaggttattctgactgattctggatcttttgcatctattccaactaaaagcact gcgaaatccttgtccgggagcagtcgtgggctgggatctatttctagtagaacaggtggc tctagaaaaagtaccgacactctgattcttagtgctaatcaggatggtagctcagtgtct tttgagtatgatgcagcatctatagatgaagatgaggacgatggaacatctgatggggag gtggcaagcatagacaaggacgatgaagaggattccagtagtgaacgggcccttgcttcc aaagtctgcacatttacttctagcggcagcaatttcatggaacagcattggtacttttgt tatacttgtgatctgactgtgtcaaaaggctgttgctctgtttgtgcaaaagtgtgtcac cgtggtcatcgtgttgtatactcacgttctagtcgtttcttctgtgattgtggagccggg ggtgttagagggagcacatgccagtgtttgaagccaaggaaattcactggaagcaatgtt gcacctgctaaaggccctggcagtttccaatcattactgcctttcacggaggatggagat caattgccagatagtgattcggatcctgatgaagatgcttctattgaagcagataactcg ctgaggctttctgtccctaacgacatccaaggtgcaattcctcgtctttatgaagaactt gaccttgaggctcaggtgcttaaaatttgtaacttgcttctgccttccatcacaaggaga agggatggagatctttcgagagataaaaatcttattttaggagtagagaaagtactatca tatggatctgatctcctgcagttgaagaaggcttacaaaagtggttccttagatcttaag attaaggcagattactccaatgcaaaggaactccgttctcttctagctagtggcgctctt atgaaatctttgctcagtgtgagcggtcgtggtaggcttgctgtgggggagggtgataaa gttgctatatttgatgttggacagcttattggacaggccactgtcgcacctgtgacggcg gacaagactaatgttaagcctctttccaagaatgtagttcgttttgaaattgtgcatctt gcttttaaccctttggctgagaattatcttgctgtcgctgggtacgatgactgccaggtc ttcactgttactcctcggggtgaagtgacagatcgtcttgctattgaattagctcttcag ggtgcttatattaggcgggttgattgggtcccaggctctcaagtgcaactgatggtggtc actaataggttcgttaagatttatgatctatcacaggacaacatcagccccttgcattac ttcacgttggcagatcagatgattacggatgctgtactctctgtggcatctcagggtaca gtctatctcattgtgctttcagaactgggaaacttgttcaagcttcagttgtcgactgaa gtcaatgcggggacgaaacaattgaatgaaaaagttgatatttccactagagatgtccat gtcaaagggtcgtctttgtacttctcatctacctataagttactctttgtatcgtatcaa gatggaagtacctttattgggcggctgaactcagatgcaacatctttaacagagatttcg gctgtatatgaggatgaacaagatgacaagcgacgaccagctgggttgcatcattggaaa gaattgatgcctggtagtgggttatttgtgtgcttttcaagctggagatcaaatgctgca cttgctgtgtccttgggagctcatgagattttctctcagaatatacgacatgcagttggt tcaaactcacctgtggttggtgcaactgcttataaacctttatccaaggacaagatccac tctcttatcctgcatgatgatggtagccttcagatattttcacatgttcaagctgcaggt gattctgggtcaaatgcaacatctgagaaggtaaaaaaattgggtccaaacatcctcagc aataaagcttacgctggtgtgaaccctgaatttcctctcgatttctttgagaagacagtg tgcatcactgctgatgtaaaattgggcggtgatgctgtcagaaatggcgattctgaagga gctaaacagagcttaacatctgaagatgggtttcttgaaagtcccagctcttctgggttt aagattacagtgtcaaattcaaaccctgatatagtaatggttggcatccgtgtacatgtt ggaaatacctcagcaaatcacatcccttctgatataactatttttcagagggtgatcaaa ttagatgaaggcatgcggtgttggtatgacattccttttactgttgccgagtctctcctt gctgatgaagaatttacagtgtcagtgggtacaactttcaatggctctgcattgcctaga atagactcactggaggtttatggacgccccaaagacgagtttggctggaaagagaaaatg gatgcagttcttgacatggaatctcgtgtgcttggaagtaattcatgggctattacatct aggaaaaagatccgttctatgcagtctgcgcctcctgaggaagaagtgttggcagacggg ctcaaacttctatcaagattgtatttgctatgcaagcctcaggggtgctcaaaagttgaa gatatgaaaccagaattaagtgtgcttaagtgcaagcagctgcttgaaactatttttgaa agtgatggagagccactactccagtcttctgcatgccgtattttgcaggctgcataccct aaaagagaaatctattaccaagttaaggatagtatgcgccttcttggtgtggtaaaatct gcagctttgatattatcaaggttgggggtgggtggttctacatcagcatggattatagag gaattcacagctcagatgcacgctgtgtctaagattgctttgcatcggaggtcaaatttg gctgcttttcttgagatgaatggttctcaagtagtagatgggcttatgcaagtcttgtgg ggaatattggagatagagcagccagacacacagaccatgaataatattgtcatatcttct gtggaacttatttattgctatgcggaatgtttggctttacatgggaaggaggctggtgga cactccgtcgcagctgcagtagtgttgttaaagaaacttttattttctcctaatgaggct gtccagacagcaagcagcctggcaatttcttcaagattgctccaagttccatttccaaag caaactatgttggctactgatgatgcggcagacaatgctacttcagcatcggcccatgtg gatacagtgactgcgtctggaggcaatgcccaggtcatgatggaagaagaaactgtcaca tcctcggttcaatattgttgtgatggttgctccactgttcctatattaaggcgaagatgg cattgcactgtttgcccagattttgatttatgtgaagcatgttatgaagtggtggatgca gatcggcttcctccaccacattcccgagatcatctgatgacggcaatcccaatagaagtg gaaaatttaggtggagagggaactgaaattcattttccctccggcgagttaagtgtttca ggcattttgccaacctcgtcaaactcaaatgtgcaaaattctaccccatctatccatgtg ctggaacccaatgagcttgaggatttctcaccttccgtgttggatccaatctcgatctct gaatcgaagcgagctgtaaattccttgcttctctccgagctcttggatcagttgagaggc tggatgttgacaacctctggtgttagagctattcctgtcatgcaacttttttatcggcta tcttctgctgtcggtggaccttttatacatagctcaaaccctgaaagcttagatctggag aaactgataaagtggtttctggatgagattaatcttaaaaaaccatttgttgccagaagt cgatcttcttgtggtgaagtcacaatccttgtctgtatgttctttaccctaatgctaaga aattggcaccagcctgggagtgatggctctgttccaaaatccggtggatcctccgataca cttgatagaagctatattcaaaatccattgtctgcttcatttgctgctgcagtatcttca gacaaccaagacaagaatgacttcactatgcagctgctaagagcttgtaatgttcttcgc caacagtcttttgttaattatctcatggatattttgcagcagctagtccatgtttttaag tcaactgctggtaatcttgaaagttcatctagttcgcaccctggttctgggtgcggggct ctactaagtgtccgaagagagcttccagcaggcaatttttctccattcttttcagattca tatgcaaaggcccatcgagtcgacatctttgccgactatcatagactcttgttggagaat actttccgtttggtctacagtctggttcgtcctgaaaagcatgagaaaagtggggaaaaa gagaaggtgtacaaactttcttccagcaaagacttgaaattagaaggatatcaagatgtt ctttgcagttatataaataatccacacacaacttttgttagaaggtatgcaagaagactc tttctgcatttatgtggaagcaagtctcactattacagtgtgcgggactcgtggcagttc tcaagtgaaattaagaggctgcacaaacatgtaaacaagactggtggttttcagaatcct gtcccatatgaaagaagtgttaaaatcataaagtgcttgtgcaccatggctgaagtagct gctgcacgtcctagaaactggcagaagtactgtttgaggcatgcagaagttttgcctctt ttgttgaagtggatattctatcttggggaggagtctgtcattcagacactcaaactccta aatttggctttctacactgggaaggatatgaaccattcttctcagaaagtggaatcaggg gatgctgcagtgggctctaataaatctgcatcacagtcgcaggatactaagaagaaaaag aaaggagatgatggaacagagtctggttctgaaaaatcttgcttagacatggaagttgct gttgacatcttcactgataaggatggtgaagtcttgaggcaattcattgattgctttctt cttgagtggaactcaagtgctgtgcgtgctgaagcaaagtgtgttcttcacggcatctgg cagcacggaaagcagttgtttaaggagaacatgttgagggtgctctttgagaaagtgaag tgtttgccgatgtatggaccaaacatagctgagtatacggaattgcaaacatggttgctt ggcaaagttcctgatgtgagcttaaagcagctaaatgctgaacttttagataaatgcttg acttctgatgtcattcagtgcttctatgagactcttcatatgcagaatgaactactggct aatcatccaaattctcgtatatacaacacattgagtggtctggtggagtttgatggatat tatttagaaagtgagccttgtgtctcttgtagctctcctgaggtgccttacagtaggatg aagctggagagcctgaaatctgagactaaattcacagataaccgtataatagtgaaatgt acgggaagctacaccattcaatctgttacaatgaatgtgcatgatgctcggaagtccaaa tcagttaaggttctgaacttgtattataacaacagacctgtgaccgatttatcagagtta aaaaataattggtcattgtggaagcgcgccaaaagctgccaccttgcgtctaatcagaca gagctgaaagtagatttccctattccaattactgcttgcaacttcatgattgaactcgat tccttctatgaaaatcttcaggcttcatcaatggaaccgttgcaatgcccaagatgtagc cggcctgtcactgataggcatggtatatgcagcaactgccatgagaatgcatatcaatgt agacaatgccgcaacatcaattatgaaaatttggactcatttctgtgcaatgaatgtgga tacagtaaatatggccgttttgagttcaacttcatggcaaaacccagctttactttcgat aacatggaaaatgacgaggatatgaaaagaggacttgcagcaattgaatctgaatcagaa aatgcccacaggaggtatcaacaacttttggggttcaaaaaacccttacttaagattgta tccagcattggtgagaatgatatagactcacagcaaaaggattctgtgcagcagatgatg gtttccttgcctggaccttcctgtaagataaatcgtaaaattgcacttctaggtgtgctc tatggtgagaagtgcaaggcagcttttgattctgtgagcaaaagtgtccagacactgcaa gggcttcgacgagttttgatgaattatctgcaccagaaacactgtgctcagaccacagaa ccttcaagatttgtggtttccaggacaccgagcagttgctatggctgtgctaccacgttt gttgtccagtgccttgagatattgcaggttctatcaaagcatcctaattcaaagagacag cttgtcgcatcgggcatcttaacggaattgtttgagaacaatattcatcaaggtccaaag tctgctcgctcacaagcaagagctgtgctttgtgctttttccgagggtgatatgaatgct gttaatcagttgaataatctgatacagaagaaagtcttgtactgccttgaacatcatcga tccatggacattgctgtggctacccgagaagaaatgttgttgctctcagagatttgttcg tcaactgatgaattttgggaatcgaggctacgtgttgttttccagttgctatttacttca attaaagtgggttccaatcatccagccatatcagagcatgtaattcttccttgcttgagg atcatatctcaggcatgtacccctccgaaagctgatatgctggacaaagaatcaagtgga aaatctcaaccatcaaaagatgctagtaattcagatgttactggtacattaggtgtgcca gccaatgtgagtagttctacgtcagagttggtggagagaaattggaatggttcacagaag actcaagacattcatttgttgagttattcagaatgggaaaagggtgcatcatatcttgat tttgtcaggaggcagggtaaagtttcacaggcattcagaggtcccggccacaagtcacga cctcagagatatgactttttagctttgaagtatggacttaggtggaagcgccgtgcttgt gctcggaataactttgcatcgtttgaactgggatcatgggtttctggacttatactaagt gcttgttcgcaatcaataagatcagagatgtgtatgttggtgaatctgctctgtgcccag agttcatctagacggttccgcttgttgaacttgttgatggcatggttgcccttgactctc tctgctgctgaaaatgctgtggagtattttgacttgctctttaagatgatagagatggaa gatgctcgcttattccttactgccgggggatgtttaagcaccatatgcaagttgattacg caagaagttaacaatatcgaatccttggagaggagtctgcatatcgacatttcacagggg ttcatactgcacaaactaatagagcttcttgggaaatttttggagatcccaaacatcaga gcaagatttatgcgagacgacttgctctctgaagttctagaagccctcattgtcattcgg ggattagtcgtccagaagacaaaattaatcagtgattgcaatcgtcttctgaaagatttg ctggatagccttctgcaggaaagcagtgagaataagcgactatttatacgggcttgtatc tgtggtttgcagattcacggagatgagaagaaaggacaaatttctttgtttatcttggag caactttgcaatctaatctgtccatcaaaaccagagtccgtgtacttcctgattcttaat aaggcccacactcaggaagaatttattaggggtaacatgaccaaaaatccctattctagt gctgaagttggtcctctgatgcgtgacgtgaaaaacaaaatatgtcatcagctggatatg ttgggtcttatagaagatgactatggaatggaattgctagttgctgggaatatcatctct ctagatctgagtgttgctcaagtttatgagcaagtgtggaagaaggccaacattcaatcg tcaaatactgttgctaatgcgaccatgctagctgctggtggtactgcttcaacaagagat tgtcctcctatgattgtgacatatcgtctccagggattggatggtgaagccacagaaccc atgattaaagagctggatgaagatagagaggaatctcaagatccagaggttgagtttgca atagcaggtgcagttagggagtatggtgggatggaaatcatattgggcatgattaagcgg ctacgagatgatttgaagtccaaccatgagcagttaatagtggtgctcaatcttctgatg tattgctgtaagataagggagaacagacgagccctattaaggctaggagctttaagtcta cttcttgaaactgcaagacgtgctttctctgttgatgctatggaggccgctgaaggcatt cttttgattgttgaggcactgaccttggaagctaacgagagtgataatatcaacattacc cagagtggtcttactatcactagtgaagaaactggtgctggtgaacaggccaagaagata gtactaatgttcttggaacgactatctcatacttctggtctgaagaaatcaagtaaacaa caaaggaacaccgagatggttgctagaatattgccttacttgacctatggtgaaccttca gccatggaagctcttgtccagcattttgatccatatctacagaactggacagaatttgat aggctacaaacgcagcatgaagatgatccaaaagatgacggcattgcacagagagcggtc aatcagaggtttgcagtggagaactttgtccgagtctccgagtcccttaaaacaagctct tgtggggagcgattgaaggatattatactggagaagggaattactggagttgcagttggg catcttagagagatatttgcagttgctgggcatcctggttacaaatctatggcagagtgg acactgggtttgaaacttccatctgttccccttatattatctatgctgagaggactatca atgggccatttgccaacacaaaactgcatcaacgagggaggcatcttacctttgctccat gcattggaaggagtatctggagagaatgagattggagcaagggctgaaaatttactggac actctctctgacaaggaaggaaatggagatgggttccttggggagaaaattctcaactta cggcatgccacaagggatgagatgaggcgtcgtgctctaaggaaaagggaagaactgcta cagggactcggaatgcggcaagagctgtcttctgatggtggagagcgtatagttgtttct cggccaaaccttgaaggttttgaagatgtggaggaagaagaagatgggttagcctgcatg gtatgcagagaaggttacagtttgagacccaatgatctgctaggagtatactcctacagc aagcgggtaaacttaggtgctggcacatcaggaagtgctagaggagaatgtgtctacacc acagtgagtcatttcaatatcatccatttccagtgtcatcaggaagctaaaagagcagat gctgctctgaagaatcccaagaaagagtgggaaggggctacccttaggaacaatgaaact ctctgtaatgccttgtttcctatcagaggtcctgctgttccattgggtcagtatgtccgc tatgtggaccagtactgggataatctcaatgcgcttggacgtgctgatggaagtcgcctt cggctattgatgtatgacattgttctgatgctcgcccgttttgcaacaggagcgtctttc agttcagacagcaaaggtggtgggaaagagagtaactccaaatttctgccctttatgatc cagatggctcgtcacctgctagatcaagggagtggttctcagcgtcgttcaatggcaagg gcaatttcgtcatatctcacctcatcctctgattctcgaccttcaccctcgtctccattg cagccttctggtggaacagaagagactgtacaatttatgatggtaagctccctcctcaca gagtcgtatgagttttggctccagcaccgccgtgccttcattcaacgagggatctaccac gcatacatgcaacacgcgcacagcaaatctttgcctcgaggatcaagttccacaagatct gaacaagtaacaagtggtagtgatgatttactacccatcattcaacctatgcttgtgtac actggtcttatagaacagctccagcagttcttcaaaccaaaacagtccacggttggggca tctactgatggcgaaggaacatcgaaagaaggcgaaggggatgatgaaaatggcttagag agttgggaagtagtaatgaaggacaaagtattggatatgaaggagatggtaggtttctca aaggagcttttatcatggttggatgatatgacttctgctggggacttacaggaagctttt gatgttattggtgccttggcagatgtgttatctggtgagaataaaagttgtgaagaattt gtgcaggcggctataaatgcagggaagaattga

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