Bacillus mycoides KBAB4: BcerKBAB4_0224
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Entry
BcerKBAB4_0224 CDS
T00642
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bwe
Bacillus mycoides KBAB4
Pathway
bwe00300
Lysine biosynthesis
bwe00550
Peptidoglycan biosynthesis
bwe01100
Metabolic pathways
bwe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bwe00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BcerKBAB4_0224
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BcerKBAB4_0224
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BcerKBAB4_0224
Enzymes [BR:
bwe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BcerKBAB4_0224
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
HTH_PafC
CBM_56
Motif
Other DBs
NCBI-ProteinID:
ABY41492
UniProt:
A9VQE6
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All DBs
Position
234490..235866
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AA seq
458 aa
AA seq
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MINRTLKQVEQMINGTGLAERYEGITIQGVSIDTRKIENGNLYVPIQGERFDGHAFVDKA
VENGAIATLWMKDVENPPENLPVIFVEDTLAALQMLAKNYRDQLDVKVVGVTGSNGKTST
KDIVTSILATKFKVQKTEGNFNNHIGLPLTILNLEENTEVAVLEMGMSSRGEIEFLSKLA
RPNAAIITNIGEAHLMDLGSREAIAEAKLEIVTGLQKGGVFVYNGDEPLLTNRVPEMNLA
AETVTFGDARANDYYPTTVTLQATGTHFKMNRDETLSFYLPVLGKHNVYNTLASMAIAKH
FGVTWEEMKQGLVTLQMTGMRMEIVKTDSGLTIINDAYNASPTAMEAAFHLMNGLDGFAK
KIVVLGDMLELGNQEVQFHYEVGKLIDPAKISYVFTYGKLGAQIAEGAKINFPKDRVKAY
DSKEELIKELQAVVGTKDVVLVKASRGMKLEEVITMLK
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgataaatcgaacgttaaaacaagtagagcagatgataaatggtactggattagcagag
cggtatgagggaattactatacaaggagtgtctattgatacgaggaaaattgaaaatgga
aatttatatgttccaattcaaggtgaacgtttcgatggacatgcttttgtagacaaagct
gttgaaaatggggcgattgctacattatggatgaaagatgtagaaaacccacctgaaaat
cttccggttatttttgtagaagatacactagcagcattgcaaatgttagcgaaaaactat
cgtgatcaattggatgtaaaagttgttggtgtaacgggtagtaatggtaaaacatctacg
aaagatattgtaacaagtattcttgcgactaaatttaaagttcaaaaaacagaaggtaat
ttcaacaaccacatcggtttacctcttactattttaaatttagaggaaaatacagaagta
gctgtattagaaatgggcatgtcaagccgcggagaaattgaatttctatctaagttagct
cgtcctaatgcagctattattacgaacattggtgaggcgcacttaatggatttaggctct
cgtgaggcgattgctgaagcgaagttagaaattgttacaggtttacaaaagggtggcgtg
ttcgtatataatggagatgagccgctattaacgaatcgtgttccagaaatgaatttagca
gctgaaacagttacatttggtgatgcgagagcaaatgattactatccaactactgtaaca
ttgcaggctactgggacacactttaagatgaacagggatgaaactttgtcattctatttg
ccagtactaggaaagcataatgtatataatacgcttgcttcaatggcaattgcaaaacat
tttggtgtaacgtgggaagaaatgaaacaaggtttagtaacacttcaaatgacaggtatg
cgtatggaaattgtaaaaacagatagtggtttaacaattatcaatgatgcttataatgct
agtccaacagctatggaagctgcgttccacctaatgaatggtttagatggatttgctaaa
aaaattgttgtgcttggtgatatgttagaacttggaaatcaagaagtgcaatttcattat
gaagtaggtaaattaattgatccagcaaaaatttcatatgtattcacatatggtaaatta
ggggctcaaattgctgaaggtgcaaaaattaatttccctaaagaccgtgtaaaagcgtat
gatagtaaagaagagttaataaaagagttgcaagcagtagtcggtacgaaagatgttgta
ttagtaaaagcatctcgcggcatgaaattagaagaagtaattacgatgttgaaataa
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