KEGG   Chelonoidis abingdonii (Abingdon island giant tortoise): 116819437
Entry
116819437         CDS       T07367                                 
Symbol
PIK3CB
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
cabi  Chelonoidis abingdonii (Abingdon island giant tortoise)
Pathway
cabi00562  Inositol phosphate metabolism
cabi01100  Metabolic pathways
cabi04012  ErbB signaling pathway
cabi04068  FoxO signaling pathway
cabi04070  Phosphatidylinositol signaling system
cabi04081  Hormone signaling
cabi04140  Autophagy - animal
cabi04150  mTOR signaling pathway
cabi04210  Apoptosis
cabi04218  Cellular senescence
cabi04370  VEGF signaling pathway
cabi04510  Focal adhesion
cabi04620  Toll-like receptor signaling pathway
cabi04625  C-type lectin receptor signaling pathway
cabi04810  Regulation of actin cytoskeleton
cabi04910  Insulin signaling pathway
cabi04914  Progesterone-mediated oocyte maturation
cabi05100  Bacterial invasion of epithelial cells
cabi05132  Salmonella infection
cabi05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:cabi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    116819437 (PIK3CB)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    116819437 (PIK3CB)
   04370 VEGF signaling pathway
    116819437 (PIK3CB)
   04068 FoxO signaling pathway
    116819437 (PIK3CB)
   04070 Phosphatidylinositol signaling system
    116819437 (PIK3CB)
   04150 mTOR signaling pathway
    116819437 (PIK3CB)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    116819437 (PIK3CB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116819437 (PIK3CB)
  09143 Cell growth and death
   04210 Apoptosis
    116819437 (PIK3CB)
   04218 Cellular senescence
    116819437 (PIK3CB)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116819437 (PIK3CB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116819437 (PIK3CB)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    116819437 (PIK3CB)
   04625 C-type lectin receptor signaling pathway
    116819437 (PIK3CB)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116819437 (PIK3CB)
   04914 Progesterone-mediated oocyte maturation
    116819437 (PIK3CB)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    116819437 (PIK3CB)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116819437 (PIK3CB)
   05100 Bacterial invasion of epithelial cells
    116819437 (PIK3CB)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cabi04131]
    116819437 (PIK3CB)
Enzymes [BR:cabi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     116819437 (PIK3CB)
Membrane trafficking [BR:cabi04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    116819437 (PIK3CB)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_p85B PI3K_rbd PI3K_C2
Other DBs
NCBI-GeneID: 116819437
NCBI-ProteinID: XP_032627030
Ensembl: ENSCABG00000010804
LinkDB
Position
Unknown
AA seq 1069 aa
MPPAMTDILDIWAVDSQIGADGLISVDFLLPTGTYINLDVPRDATICHIKQLLWKQAHSY
PLFHLLMEIDSYMFSCVNQTAVREELEDETRRLCDVRPFLPVLKLVTRNCDPGEKLDSKI
GVLIGKGLHEFDALQDPEVKEFRSKMRRISEEKLLSLVGLSWVDWLKHSYPPEQEPSIPE
NFQDKLYGGNLVVAIHFDKCQDVFSFQVSPNINPVKLNELAIRKRLTIHGKEDEVDPSDY
VLQISGRLEYIFGDHPLIQFQYIHKCVMNRILPHLTLVECCSIKKMCEQEMIAIEGAINR
KSSNLPLPLPPKKTRTVTQLTQSVWDISNPFKIMLLKGNKLNTEETAKVHVRAGLFHGTE
LLCKPIVSAEISGRSEHVWNETLEFEINVCDLPRMARLCFAVYAVMDKMKTKKSTKTINP
SKYQTIRKAGKVHYPVAWVNTMVFDFKGQLKSGDLLLHSWTSFPDELEEMLNPMGTVRTN
PYTENATALHIKFQEYSNLPIYYPPFDKILEKAAEIAKSSENAGMAGRGGKKFYIELKEI
MERDPLTQLCENEMDLIWTLRYDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWSKL
PPREALELLDFNYPDQYVREYAVGCLKQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLV
ERALANRRIGQMLFWHLRSEVHIPSVSIQFGVILEAYCRGSIAHMKVLSKQVEALSKLKT
LNSIIKLNAMKQSKAKGKDAMHTCLKQNAYREALSDLQSPLNPSVILSELYVEKCKYMDS
KMKPLWIVYNNKMFGGDLLGIIFKNGDDLRQDMLTLQILRLMDLLWKEAGLDLRMLPYGC
LATGDHSGLIEAVSAAETIADIQLNSSNVAAAAAFNKDALLNWLKEYNLGDDLDRAIEEF
TLSCAGYCVATYVLGIGDRHSDNIMVRKNGQLFHIDFGHILGNFKSKFGIKRERVPFILT
YDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDI
QYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
NT seq 3210 nt   +upstreamnt  +downstreamnt
atgcctcctgccatgacagacatacttgacatatgggcagtggattcgcagataggagct
gatggtttaatctctgtggacttcctgctcccaactggaacctacatcaacctggatgta
cctcgagatgccaccatatgccatattaaacagctactatggaagcaggcacacagctac
cctctatttcatctccttatggagattgactcttatatgttctcatgtgtgaaccagacg
gctgtacgtgaggaactagaggatgaaacacgaaggttgtgtgatgttagaccctttctt
cctgtcctcaaactagtgacaagaaactgtgacccaggggaaaaattggattccaaaata
ggtgtccttataggaaaaggcctccatgagtttgatgccttacaggaccctgaagtgaaa
gaattccgtagtaaaatgcgacgaatcagtgaagagaaactcctgtcgcttgtgggcctg
tcctgggttgactggctaaagcacagctatccaccagaacaagaaccctcaatcccagaa
aactttcaagataaactctatggtggaaatcttgtagtggccattcattttgataagtgc
caggatgtatttagttttcaagtgtctcctaacataaatcctgtcaagttgaatgaattg
gcaatccgaaaacgtttgactatccatggaaaggaagacgaagttgatccttctgactat
gtgttgcaaattagtggaagactggaatatatttttggtgaccacccattaattcagttc
cagtatatccataagtgtgtgatgaacaggattcttcctcacctgacactggttgagtgt
tgcagcataaagaaaatgtgtgaacaggaaatgattgccatagaaggtgccataaaccga
aaatcatccaatcttcctcttcctctgccaccaaaaaaaacacgaacagttactcagctg
actcagagtgtgtgggatattagcaaccctttcaagattatgctgttaaagggtaataag
ttgaacacagaagaaactgccaaagttcatgtcagggctggtcttttccacggaactgaa
ctcctttgtaagccaattgtaagtgcagaaatatctgggagaagtgaacatgtttggaat
gaaacattggaatttgaaatcaatgtctgtgacttgccaagaatggctaggctgtgcttt
gcagtttatgctgtgatggataaaatgaaaactaaaaagtcaaccaagaccattaatcct
tcgaaatatcagaccatcaggaaagctggaaaagtgcactatcctgtagcctgggtaaat
accatggtatttgattttaaaggacagttgaagagtggagacctcttactgcacagttgg
acatcatttcctgatgaacttgaagaaatgttgaatccaatgggaacagtacgaactaat
ccttacactgaaaatgcaacggctttgcacattaaatttcaagaatattcaaacctgcct
atttattaccctccctttgataagatacttgaaaaggcagctgagattgcaaaaagcagt
gagaatgctggcatggcaggtcgtggtggcaaaaagttctatattgaactaaaagaaatc
atggaaagggaccccttgactcagctatgcgaaaatgaaatggatcttatatggactttg
cggtatgactgtcgtgagaatttcccacaatcactaccaaaactgctgctgtctataaaa
tggaacaaacttgaagatgttgctcagcttcaggctcttcttcaaatatggtcaaaattg
cctcctagagaagcattagagttgctggatttcaattatccggaccagtatgtgagagag
tatgcagtgggctgtttaaagcaaatgagtgatgaagagctctctcagtatcttctccag
cttgtgcaagttctgaaatatgaaccttttctcgattgtgccctctccagattcctggta
gagagagcacttgctaataggaggattgggcagatgctattttggcatctaaggtcagag
gtgcacataccctctgtctcaatacagtttggtgtaatacttgaagcttactgccgagga
agtattgctcacatgaaagtgctttccaaacaggttgaagccctcagtaaattgaagacc
ttaaatagtataataaaactgaatgccatgaagcaaagcaaagcaaaaggaaaagatgca
atgcacacctgtttaaaacaaaatgcatacagagaagcactttctgacctgcagtctcct
ttgaatccctctgttatactatcggagctatatgttgagaagtgtaaatatatggattct
aaaatgaagcctttatggatagtatacaacaataagatgtttggaggggatctcttaggg
atcatctttaaaaatggcgatgatctacgacaagacatgttgacactccagattttgcgt
ttgatggacttactttggaaagaagctggtcttgatctccggatgttgccatatggttgt
ttagcaacaggagaccattctggccttattgaggctgtttctgctgcagaaaccattgca
gatattcagttaaatagtagcaatgttgctgctgctgctgcattcaacaaagatgctctc
ttaaactggctaaaggaatacaatttaggagatgacctggatcgagccatcgaggagttc
accctgtcttgtgctggctactgtgtagctacttacgtactgggcattggtgacagacat
agtgacaatatcatggtcaggaagaatggtcagctctttcacatagattttgggcatatt
cttgggaacttcaaatccaaatttggaattaaaagggaacgagtgcctttcattcttacc
tatgatttcattcatgtcattcaacaaggcaaaacggggaatactgagaaatttggccgg
ttccgccagtgttgtgaagatgcatatttgattctgcgaagacatggaaatctatttatc
acactctttgcactgatgttaactgcagggcttccagagctaacttctgtcaaggatatc
cagtatctcaaggactctcttgccttagggaagagtgaggaagaagcgctaaaacaattt
aagcaaaaatttgatgaagcgctccgggaaagttggactactaaagtgaactggatggct
cacactgttcgaaaagattacagatcctag

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