Caldithrix abyssi: Cabys_2078
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Entry
Cabys_2078 CDS
T04549
Name
(GenBank) UDP-N-acetylmuramyl pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
caby
Caldithrix abyssi
Pathway
caby00300
Lysine biosynthesis
caby00550
Peptidoglycan biosynthesis
caby01100
Metabolic pathways
caby01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
caby00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Cabys_2078
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Cabys_2078
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Cabys_2078
Enzymes [BR:
caby01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Cabys_2078
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
APF18827
UniProt:
H1XUH6
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Position
2498770..2499942
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AA seq
390 aa
AA seq
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MFGKPGFKKDFISDKEKKEILRRRQAFTNPIIAVTGNLGKTSTISMIETILSARGKVLRH
PNGCGNLQNNFSTLKKLNNTYDFGLFELNHQKGRQFVELVHLIRPNIAIVTNLGDAHLNY
LERMIRQAIEKASLLKYMDQDGIAILNKDDELSYNIVKQIKNLNVIQFGLNPHADFYATD
IEQFGPGGMRFKLNGRFEIQLPIFSIQDLYNFLAAVAAVAHIGFSLNDVVEILNTKFSLP
EGRGKVLKYGSIYVIDESYISTPRSVSKAARVLSTFEQYSEQLVLIVGDMADAGINVEQQ
HINMGYFLSALPIDLLITVGEYAKFIGKGFEFIKTSKKLCFSVNSLNEVFEILDIHLKNK
STIAIKGLGKVAMHRFQSYFKTQQPVSTIN
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
ttgtttggtaaaccgggatttaaaaaagattttatttctgacaaagaaaaaaaagaaata
ctgaggcggcgccaggctttcaccaatccgattatcgccgttaccggtaatttaggcaaa
acttcaaccatttccatgatcgagaccatcctctccgcgcggggcaaagtattaaggcat
ccaaacggttgcggaaatctgcaaaataatttcagtactttaaaaaaactaaacaatact
tacgattttggtttatttgagctcaaccatcaaaagggccggcaatttgttgagctggtt
catttaatccgccccaatatcgccattgtaaccaacctgggagatgcgcaccttaactat
ctggagcgcatgattcggcaggccatcgaaaaggcttcgttgctaaaatacatggatcag
gacggaatcgccattttaaataaggacgatgaactcagttacaacattgtaaaacaaatt
aaaaatttgaatgtcattcaattcggtttaaatccgcacgccgatttttatgccaccgac
atcgagcaatttgggccgggcggcatgcgttttaagttgaacggtcgttttgaaattcaa
ctacccattttttccattcaggatctgtacaattttttggctgccgtggcggcggtggcg
cacattggcttcagtttgaacgatgtggtggaaatattaaatacaaaattttctctgcct
gaaggacgcggcaaagttctaaaatacggatcgatttatgtgatcgacgaaagctacatc
agcaccccgcgttcggtaagcaaagcggcgcgcgtgctctccacctttgagcagtattct
gaacaactggtattgatcgtcggcgatatggcggatgccggcataaacgtggagcagcaa
cacattaatatgggctattttttgtccgctttgcccattgatttattgatcaccgttggc
gagtatgccaaatttattggcaagggatttgaatttattaaaacttctaaaaaactctgc
ttttcggttaattcgctaaacgaagtctttgaaattttagacattcatcttaagaacaaa
agcaccattgccattaaaggattaggaaaggttgccatgcatcgatttcaatcgtatttt
aaaacgcagcaaccagtaagtacaatcaattaa
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