Cutibacterium acnes KCOM 1861 (= ChDC B594): RN83_04335
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Entry
RN83_04335 CDS
T04624
Name
(GenBank) UDP-N-acetylmuramyl peptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cacn
Cutibacterium acnes KCOM 1861 (= ChDC B594)
Pathway
cacn00300
Lysine biosynthesis
cacn00550
Peptidoglycan biosynthesis
cacn01100
Metabolic pathways
cacn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cacn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RN83_04335
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RN83_04335
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RN83_04335
Enzymes [BR:
cacn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RN83_04335
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ALD69416
UniProt:
A0AA44ZEI0
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Position
935412..936869
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AA seq
485 aa
AA seq
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MRVLDVATLAQWVEAAPVNDSAQVGPDVVIDTRKVTPGALFIALPGTRVDGHDFTQAAQD
MGAAAVLVTRRTDAQLPHLVVDDGQAGLSRLARHVVATERERGMRAIAVTGSSGKTSTKD
MLAQILETFGPTVAPVGSFNNEIGVPLTACRSNENTSFLVSEMGTRGLGHISWLTSIVTP
DVAMVLNVGSAHLGEFGSREIIAQAKGEIVEALSVDGWAVLNAADTLVAGMAPRTRGHIA
WFSPDADHRRPDADIEVWAESTHADDLDRHSFTLAARRGESTWRSPVRLMTMGAYQVANA
VAATAAALAALAMNDDIDDESVTRIAEALSNAVSRSAMRMQLRERADGLVLVEDCYNANP
DSMAASLTAMGHVLATRRARDPQTRGVAVLGDMLELGQDSARLNAESGRRAAHAGFDVII
AVGDEAKNIAEGARAEGARVIVSTVEDASGSLGWTSHDVVLLKASRGLALERVGRDVFEE
REAQA
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atgagagttctcgacgttgctaccctcgcgcagtgggtcgaagcagcaccggttaatgat
tctgcccaggtgggcccggacgtcgtcattgatacccggaaggtaactccgggcgctctg
tttatcgctcttcccggcacccgggtagacggtcatgacttcactcaggcggctcaggac
atgggcgctgccgctgtcctggtcactcggcgcaccgacgcacagttgccccatctcgtt
gttgacgatggtcaagccggcctatctcgactggcgcgtcatgtcgtggcgactgaacga
gaacgtggcatgcgtgccatcgctgtgactggttccagcggtaagacaagcaccaaggac
atgctggcccagatccttgagacttttggcccaacggtggctccggtggggtcgttcaac
aatgaaatcggagttcctctgacggcgtgccgcagtaacgagaacacctctttcttggtg
tcggaaatggggactcgcggtttgggtcatatctcctggctcacctccatcgttactccc
gacgtagccatggtcctcaacgtcgggagtgcccacctgggcgagtttggttcgcgagag
atcattgctcaggctaagggtgagatcgttgaggccctcagcgttgacggttgggctgtg
ctcaacgccgccgatacccttgtcgccgggatggcaccgcgcacccgtgggcatattgca
tggttcagccccgatgctgaccatcgtcgcccagacgccgacattgaggtgtgggccgaa
tcaacccatgccgacgacctggatcgtcactcctttacccttgccgcccgccggggtgag
tccacctggcgtagccctgtccggctgatgacgatgggcgcttatcaggttgcaaatgcc
gtggctgctactgctgctgcgctggcagccttggctatgaatgacgacatcgatgacgaa
tctgtcactcggatcgccgaggcgctcagcaacgccgtgtccaggtcagctatgagaatg
cagttgcgtgaacgcgccgatggcttggtgctggtcgaggactgctacaacgccaaccct
gactcgatggccgcttcgttgacagcgatggggcatgtcttggcgacgcgccgagctcgg
gaccctcagactaggggcgtcgccgttttgggcgacatgctcgagcttggacaggactct
gctcgtctcaatgcagagtccggtcggcgagcagcccacgctggattcgacgtcattatc
gctgttggcgatgaggccaagaacattgccgaaggtgcccgggccgaaggcgcacgtgtg
attgtttccaccgtggaagatgcttctgggtcactaggttggacctcacacgatgtcgtt
ttactcaaagcttccagaggtctggccttggagcgagtaggacgcgacgtgtttgaggaa
agggaggcccaggcgtga
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