Cutibacterium acnes KCOM 1861 (= ChDC B594): RN83_05060
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Entry
RN83_05060 CDS
T04624
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cacn
Cutibacterium acnes KCOM 1861 (= ChDC B594)
Pathway
cacn00290
Valine, leucine and isoleucine biosynthesis
cacn00620
Pyruvate metabolism
cacn01100
Metabolic pathways
cacn01110
Biosynthesis of secondary metabolites
cacn01210
2-Oxocarboxylic acid metabolism
cacn01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
cacn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
RN83_05060
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
RN83_05060
Enzymes [BR:
cacn01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
RN83_05060
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
ALD69533
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Position
1094096..1095841
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AA seq
581 aa
AA seq
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MTHIQPRPCQLTSPMPSGRYKPFVPHTLPDRTWPDKTLDHAPRWLSTDLRDGNQALVDPM
TPARKMRMFELLVGMGYKEIEIGFPSASQTDFDFVRQVIESGIVPDDVTISVLTQAREDL
IERTMRSLVGAHRATVHMYNAVAELFRRVVFNIDEKQCIDLAHRGTEWVVRYADKYLGDV
EFGYEYSPEMFSQTRTDFAIDVCHSVMDVWQPGPGREIILNLPATVEMSTPNTYADQIEY
FCRNIRDREHVCVSLHPHNDRGTAIAAAEFAQMAGADRVEGCLFGHGERTGNVDLVTLGM
NLVSQGVDAGIDFSDMPKIRRTVEYCTGLPVPARQPYAGDLVFTAFSGSHQDAIKKGLED
LERQAQEQGIGIHEVDWQAPYLTIDPHDVGRTYEAVIRVNSQSGKGGMAYLLKTEHQVDL
PRRLQIEFSRAVQNYTDDQAREISHDEIWDLFNREYLQVPGIELVSRTTSTETGTYQLTA
NLRINGADTQIRGEGNGAMSAFIDALVSLDIVVHVLDYSEHAMTAGGTARAAAYVECEIG
DGETSQILWGVGIDPDITQASLKAVVNAVNRSRRQTLDRES
NT seq
1746 nt
NT seq
+upstream
nt +downstream
nt
atgacgcacattcagccccgtccctgccagctgactagcccgatgcccagcgggcgttat
aaacctttcgttccgcacacgttgccggatcgtacctggccagacaagaccttggaccat
gctccgcggtggctgtccactgatttgcgtgatggcaaccaggcgcttgttgaccccatg
actccggctcgcaagatgcggatgttcgaacttcttgttgggatggggtacaaggagatt
gaaattggcttcccctcagcttctcaaacggatttcgacttcgttcggcaggttattgag
tccggcattgtccctgacgacgtcactatttcggtgctgacccaggcccgtgaggatctc
atcgagcgcaccatgcggagcttagtcggcgctcaccgtgccactgtccacatgtataat
gcagttgccgaactcttccgacgcgttgtcttcaacatcgacgaaaagcagtgcattgac
ctggcgcaccgtggtactgagtgggtcgtcaggtacgccgacaagtacctcggcgacgtt
gagttcggctacgagtactctccggagatgtttagccagacccgcacggacttcgctatc
gacgtctgtcactccgtgatggacgtgtggcagccggggccaggccgtgagattatcctt
aatctgccggctaccgtcgagatgagtactccgaacacctacgccgaccaaatcgagtac
ttctgccgcaatatccgtgatcgtgagcacgtgtgcgtctctttgcacccgcacaatgat
cgtggcacggcgatcgcggccgccgagttcgcgcagatggcgggcgccgatcgcgtcgag
ggctgtctctttggccacggcgagcgcaccggcaacgttgatctcgtcaccttaggtatg
aatcttgtcagccagggagttgacgcgggtatcgacttctctgacatgccaaaaatccgc
cgcaccgtcgagtactgcactggactaccggtgccggcacgccagccctacgccggcgac
ctcgtcttcacagccttttcgggctcgcaccaagacgctatcaagaaaggcctggaggac
ctcgaacgccaggcccaggagcagggcatcggtatccacgaggttgactggcaggccccc
tacctgaccatcgacccacacgacgtcggacgcacctacgaggctgtcattcgcgtcaac
agccagtccggtaagggcggcatggcctacctcctgaagaccgagcaccaagtcgacctg
ccgcgtcgtctgcagatcgagttctcccgtgcagtgcagaattacaccgatgaccaagcc
cgcgagatcagccacgacgagatctgggatctgtttaaccgcgagtatctgcaagtgcct
ggcatcgagctggtgagccgcacgacgtccaccgaaaccggtacctatcagctcaccgcc
aaccttcggattaatggggcggacactcagatccgtggtgagggtaacggtgcgatgtcg
gctttcatcgacgcactggtctccctcgacatcgttgtccacgtgctcgactactccgag
cacgccatgacagcgggtggtactgcgagggccgccgcgtatgtcgagtgtgaaattggg
gacggcgagacctcacaaattctatggggagtcggcattgaccctgatatcacccaggct
tccctgaaggcggtcgtcaacgcggtaaaccgctcccgtcggcaaaccttggatagggag
tcatga
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