Clinocottus analis (woolly sculpin): 137779784 Help Entry 137779784         CDS       T10471                                  Name (RefSeq) ryanodine receptor 2-like   KO K04962   ryanodine receptor 2 Organism cana  Clinocottus analis (woolly sculpin) Pathway cana04020   Calcium signaling pathway cana04260   Cardiac muscle contraction cana04261   Adrenergic signaling in cardiomyocytes cana04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:cana00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     137779784    04020 Calcium signaling pathway     137779784  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     137779784    04261 Adrenergic signaling in cardiomyocytes     137779784  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cana04040]     137779784    04990 Domain-containing proteins not elsewhere classified [BR:cana04990]     137779784 Ion channels [BR:cana04040]  Voltage-gated cation channels   Ryanodine receptor    137779784 Domain-containing proteins not elsewhere classified [BR:cana04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    137779784 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR Ins145_P3_rec SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_6 EF-hand_1 EF-hand_8 Motif Other DBs NCBI-GeneID:  137779784 NCBI-ProteinID:  XP_068424074 LinkDB All DBs Position Unknown AA seq 4971 aa AA seqDB search MADTGGEADDEFQFLRTGDEVVLQSTFTSQEEHVKLCLAAEGFGSRLCRLEPTSNCKNVP PDLSVCGFVMAQCLSVRALQEMLAHSEHLAAEVRSQVEAGGSHRTLLYGQAVLFLHSYSG MYLSCLSSSHASTDKLAFDVGLQEDKAGEACWWIVHPASRQRSEGEKVRVGDDLILVNVS SERYLHLSFGTALDNKSLSESLIVNAAFQQTLWSVAPICSGGGVAQGYLKGDDTLRLLHS HSDACLTIPSTEQGEELQRIMHYETGSVSSHARSLWRLEILRVVWSGRHACWGQPYRLCH VTTGRYLGLTEEKGLHLVDRHKADVSTTSFCFRSAKEKHDTGTKTHIDGMGVPEIKYGDS ICYVQHVESGLWLTYQAIDAQSTRMGWAQRKAILHSEGHMDDGLTLSRCQREESHTARLI RSATLLFTRFIRKLDSFTKQGNLTSVSLPMEIVTRSLQDLINYLQPPLEGLGHEAKQNIM TALKNRQNMFQEEGVIDLVLDCIDRLHQYSSGSHFGAQSDRGEEWVHMLNNFYELLAALI RGNRLSCAHFSASLDWLISRLDRLEASCGVLEVLHCVLVESPEALNVIKEGHILSIISFL DKHGRNHKVLEVLCSLCVCHGVAVRSNQNLICDNLMPGRDLLLQTRLANQATSMRPNIFL ALGEESAQHRMWYYELVVDHVDSFLTSEPTHLRVGWASSEGYQPRPTGGDGWGGNGVGDD LYSYGFDGLHLWSGCVGRRVNSPFPHLLKDDDVVSCCLDLSATCISFRVNGLPVQGMLEN FSANGLLYPVVSFSAGVKVRFLFGGQHGEFRYLPPPGFASCSDALLPRVKLKLEPCQKYI LDRGEGTQELIGPLVPVTPMTFTPTPVDISKVALPPQLEDIREKMAENIHELWAMDKIDL GWTHGPVRDEVKRHDPCLVEFSKLPEQEKNQNLQMTQDTLRTLIALGFHIGLTDDHAEES VKYMRLANKYEQPSGYRPAPINSSQVVLSPAHKEVVTLLAENDHNVWARERIKQGWTYGA QQDVKVKRSPYLVPYSLLDERRRRSGRESVREAVCTLLAYGYSLEPLNQERTTLSNTCLF SAEKCRVFRPDKSYSVTRGKWYFELEIVTAGNMRVGWARPGCTPDKELGSDDQAYVFDGF EAQWYHQGVEPLGRRWQRGDVAGCLVDVAERTMIVTLNGEVLFNDRGSELAAKDFDIGDG LLPIVSVGVNQMGRLNLGHQVSSLQYFTVCGQQEGYEPFAVNMARDPAMWMSWKQPQFTS IMPDDQNLQVSRVSGSKDSLSSLRVSQRLFAHHGGGSEMGFYRLSMSIQCEAILTRPAGG VLPVASSSLSPGRKEQEEVDSDFEVLMKSAHSFAGSRDELNHKDHSHDKTSRLKHRFMLK RTKPELISTNSSARLLEDVVVDKDSYDHLLQSSRYHYSVRVLPGQEPFNVWAGWVTSDFH QQDMTFDPDSVLTVTVTLGDDSGKVQESVKRCNCYMVCAGDATGLSQSRRSTGLEIGCLV DTATGLLTFTSSGVEMATFYQVEAGTKLFPAVFVKPTTSHMFQFEMGSIKNVMPLSAGLL RSQRRNATPQCLPRLQVQNLNPVSWIRVPACALKVMVDRPDERHGWRVQCHEPLQVMTLQ IPDENRSVNILELSELDDLLTFHRHTLLLYCSLCALGNTRVCHALCSHVDQSQMLHAIQN PHLPGPLRSAFYQLLTQVHLSSHTTACHMMNHEYIVPMTDQTREITLYPSPAHGVNGENG LPPEGISNTRLSTSLKPQMHFSSPCFVRSDEMEGGGTGDIARTDSPEIPLDMLKNLTVEM LTAGVWAVGQGVRDPVGGSIELLLVPLIRLFYTLLVMGVFGDEDLGKVLRLIEPGVFSLD AGTIEKEEEEEEEEVSDDEKECNGGNKKEDYPLKQGLLQMKLPEAVKLELCHLLSYLCDC QVRHRVEAVVAFSDNFVGQLQENQRFRYNQVMQALNMSAALTARKTKEFRSPPQEQINML LRFREDEQQDNCPCPVEVQQLLHDFHHLLSTHCGIELDSDTEDEEDAETSLKDQLLSLVA RVIGLMKTPIQVEGSRPQSTSKCIDSLKTLISETMVRWAQETEMEDPELVRVVFSLLHRQ YQGLGGQMAGHLCRAYTISQASVEDTMALLSSLSQIRSLLSVRMGKEEERLMIRRLGDIM NNKVFYQHPNLMRALGIHETVMEVMVNVLGEGESKEITFPKMVASCCRFLCYFCRISRHN QGALFDHLSYLLENSSVGLASPSMRGATPLDVAAASVMDNNELALALREPNLETVVQYLA GCGLQSCPMLVAKGYPDIGWNPVEGERYLNFLRFAVFCNGESVEENAYVVLRLLIRRPEC FGPALRGDEGNGLLAAMKEAIQISEDPSMDGPRTTHQSNRTLDVVQDNDDDLIHMGHAIM TFYSALIDMLGRCAPEMHLIHQGKGEAIRIRAILRSLVPIQDLEGVISISFQIPSVSQDG LAVEPDQSTVFCPDHKAAVLLFLDRVYGIENQNFLLHLLEVGFLPDLQAAVSLDTAELGS TDMALALNRYLCTSVLPLLTKCSALLCPLEDHASLVDSLIQAIYNLSRALSLTKAQRDTI EECLLAVCSELQPSMVQPLLRRLVFDVPHLTENSKMPLKLLTGHYEQRWKYYSLAGEPGD HGLASEEELHLSRKLFWGVFNALAKKAYEAQLFRLSVQCLAAVAMALPPDHMDSSCVSHT ERNASMDTEGHFDPRPVDTSSVSVPERLEFVVNKYAEHTHEKWSLDKFANGWVHGEQLCE NTKVHPLLKPYRAVAEKEKEAYRWAIKETLKSMLAFGWTIKRTKEGDAFGPQTCTRTVSQ SGQLSFEGASTFSPKPMDMSSITLSWDQCAMAEQLAENYHNAWAKRKKCELESKGRGGHS MLAPYDTLTAKEKSKFRERAKDILKFLQLNGYTVWRDRKTVEIDFPATANCFGYTLLQRL LSHTEDAQEHILELARGQMSKGENSPHQQAIHFFPKVILPLLEQFVKSHCLYFLSTSLCS RSYATKKEKEMIASLFCKLAALVRHRISLFGNEVSSVASCLHVLSRALDARALMNLAPES IQASLHSFFEAAATDLEMTVENLSVTLVCLPQSRNQSARGVAKVLGFTTAVLLPTLTSLF QHLGNQNYGVDLLVGSIQLSCYRILNSLLALGTSSSIYMEGQRPAAGACLAALAGTFPVC FLEPSLNQDNPYSIYNSMSAAQREDLGLPDQVEDMCPLLPSLEQALGEVEKLAGAGAGTR QAHYIQVTEVTLPMLCSYVSRWWYWGPEGQPDGPICTSVTPQHASDLLGHILRIIHNHVG ASQGDWMKELAVFSQPITCKAGTELLNSHFLPLMEKLRKRAKCVLLEEEQMKAEGCDTSE AELQIQEKFTVLVRDLYAFYPLLIPFVDSNRASWLKDLNPDAEQLFSMVAEVFTFWAKSH NFKWEEQNFVVQNEINNLAFLVNTNKMSKVSHIHPLFDHEQRMMKRKGDRYSTHTSLIVA SMKRLLPVGLRVCFPSDYSLIMLAKSGFAQKNTRDEIRENISNCLINLQYQASDCLQQET LHAEHRSQLGVFPDAQQTVNRILEVAQVLYYLDQVEHPQRSKKPAWHKVLSKQRKRAVVA CLRMAPLYNLPRHRAVNLFLQGYNKSWISAEDHNFEEKLVEDLAKGGVTELFGGDKERIK NVEESDKPIDPLLQLITHFSRSALMERNKLENDGLYKSYAAIMAKSCHREDDDDEEQEVE SFEEKEMEKQKLLYQQARLHRRGASEMVLQTISSSKGAMGSMIAPTLKLGIAVLNGGNAT VQQRMLDYLREKQDVGFFQSMAGLMRSCSVLDLNAFERQNKAEGLGMAKDETSGEKVMPD KDVTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIITTVDYLLRVQESISDFYWYY SGKDVIDAHGQQNFSKAIEVAKQVFNTLTEYIQGPCSGNQQSLAHSRLWDAVVGFLHVFA HMQMKLSQDSSQIELLKELMDLQKDMVVFLLSMLEGTVVNGTIGKQMVDMLVESSGNVKM ILKFFDIFLKLKDLTSSDAFKEYDPDHKGCISRKDFQKAMENCKRFSQSEIHFLLSCMKT NDSDVVDYEAFVDRFHEPAKDIGFSFAVLLTNLSEHMPNDSRLKAFLELAECVLTYFQPH LGRIEILGGGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVITEGGEKEKMEMFVNF CEDTIFEMQLAAQISGSDTGERCADKGAEEKSEEEDVGNGGRFFPHHWLLLLLSLLSVKN LKTVMKMTLKDIFMSAVLLFRFILMAQVRCIRVVIGGVSYVLYIAFISGGLIEGAKRMRV SDLLGCVLEPTLDEVTEVPSGVARLRKDSASFSSQRELREMGHVAAVTSPREMDALSDIF GLKVKKEGGQYRLITQDLTASLTHLFNASSKTIASADVSETHQETAHSATEEKTRDETML ELQNTNFCRGKETEKKTGKEKAEARWKVKGYNKSEESESQHSALWEKIITHNKSLLNYFA RKFYSMRLLALFVAFAINFILLFYKVRVASLPASQEEEAVVTSVNSDGPDSAANDNKGRD YFVLEESSGYMEPSLHFLAVAHTVISFCCIIGYYCLKVPLVIFKREKEVARKLEFDGLYV IEQPPEEDIKGQWDRLVINTPSFPSNYWDKFVKRKVMDKYGDFYGCEKISELLGLDRAGL DFSSGRNERRRLKRQASWSALFNSIDIKYQVWKLGVVFTDNSFLYLAWYMVMSILGHYNN FFFAAHLLDIAMGFKTLRTILSSVTHNGKQLALTVGLLAVVVYLYTVVAFNFFRKFYNKS DDMDTRDMKCNDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDDFEVERIVFDITFFFFVIV ILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFVCGIGSEYFDTVPHGFETHTLQEHNLA NYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPVGDCFRKQYEDQLG NT seq 14916 nt NT seq  +upstreamnt  +downstreamnt atggccgacactggaggagaggccgatgacgaattccagtttctacgaacgggagatgag gtggttttgcagagtaccttcacctcccaggaggaacatgtgaagctctgtcttgcagca gagggatttggcagcagactctgcaggcttgagcccacttctaactgcaagaatgtgcct ccagacttgtctgtgtgtggcttcgtcatggcccagtgtctctctgttcgagccctgcag gagatgctggctcatagtgagcacctggctgcagaggtgagatcacaggtggaagctgga ggaagccatcgcacccttctatatggccaggccgtgctgttcctacactcatacagtggc atgtatctcagctgcttgtcctcatctcacgcttcaaccgacaagctggctttcgatgtc ggtctgcaagaggataaagcaggtgaggcgtgttggtggatcgtccacccggcatccaga cagaggtcagaaggggagaaagtgcgtgtcggagatgacctcatactggtcaatgtttcc tctgaaagatatctgcacttgtcctttggcacagcattggacaacaaaagcttgagtgaa agcctgattgttaatgcagccttccagcagactctctggagcgttgctcccatttgctct ggaggtggggttgctcaaggatacctgaagggggacgacacactgcggctactccacagc catagcgatgcatgtctgactattccatccacggagcagggagaggaactgcaaaggata atgcattatgagactggatcagtttccagccatgctcgctctctctggaggctggagatc ctgcgagttgtttggagtggcagacatgcatgctgggggcagccttaccggctctgccat gtgactactgggaggtacctgggacttacagaggagaagggcctgcatctggtcgaccga cacaaggccgatgtcagcacaacctccttctgctttcgatcagcaaaggagaagcacgac actggcacaaagactcatattgatggcatgggggtcccagagatcaaatatggagactcc atctgttacgttcagcatgtagagtcggggctctggctcacctaccaagctattgatgct caatccacacgcatgggatgggcgcagcgaaaggccattttgcacagtgagggtcatatg gacgatgggctgacgctgtctcgctgtcagagggaagaatctcacacggccagactcatc cggagcgctacactcctcttcactcgctttatcaggaaactggatagttttacaaaacaa ggaaacctcacatctgtcagtctgccaatggagatagtgacacgcagtctgcaggatcta ataaactatctccagcctcctttggagggtcttggccacgaagctaaacagaacatcatg acagcactaaagaatcggcagaacatgtttcaagaagagggtgtgatagatttggtcctg gattgtattgaccgtctacaccaatatagtagtggctctcattttggtgctcagagtgac agaggagaagagtgggtgcacatgctcaacaatttctatgagctactggctgctctgatc cgaggaaaccgtctgagctgtgcacatttctcagcttctctcgactggctgattagcagg ctagaccgtctggaggcctcttgcggagtcttggaggttctacactgtgtcttagtggaa agtcctgaagcactcaacgtcatcaaagaaggacacattctctctatcatctcttttcta gacaagcacggacgcaaccacaaggtgctggaggtgctgtgctccctgtgtgtgtgtcat ggtgtcgctgtgcgatccaatcagaacctcatctgcgacaacctgatgccaggcagagac ctgctgcttcaaacacgtctggcaaatcaggccacaagcatgagaccaaacatctttttg gctctgggcgaggaatcagcccagcatcggatgtggtactatgagctcgttgtagatcat gtcgactccttcctcacatccgagcccacccacctgcgtgtcggctgggcaagctctgag ggataccagccgaggcccacaggaggggacgggtgggggggcaatggagtcggagatgac ctctactcgtatggctttgatgggcttcatctgtggtcaggctgcgtgggccgcagagtg aactctcccttccctcacctgctgaaagatgacgatgtggtcagctgctgtcttgacctc agtgctacctgcatctccttccgagtcaacggcctgcctgtgcagggcatgctggagaac ttcagtgcgaacggacttctttatcccgtggtcagcttctctgcaggagtcaaggttcgt tttctgtttgggggacagcatggagagtttcgctacctgcccccaccaggttttgcttcg tgctctgatgctttgcttccgagagtcaagctgaagttggagccatgtcagaaatacatc ttggatcgtggagaggggacacaagagctcatcggccccttagtacctgtaactccaatg acctttactcccacaccagtagacatcagcaaggtagcattgcccccacaacttgaggat atcagagaaaaaatggctgaaaatatccatgaactctgggcaatggataagattgatctt ggatggacacatggacctgtgcgagatgaagttaagaggcacgatccgtgtctggtggag ttctccaagctgccggagcaggagaagaaccaaaaccttcaaatgacccaggacaccctc aggactctcattgctcttggtttccacattggtttgactgatgaccatgctgaggagagc gtcaaatacatgagactagccaacaagtatgagcagcccagtggctatagaccggcacca ataaactcgagccaggttgttctgagcccagcccacaaggaagtggttaccttgttggca gaaaatgatcacaatgtatgggctagagagcgcatcaagcagggatggacctacggagcc caacaggacgtgaaagtgaagcgtagcccgtatctcgtgccctacagcctccttgatgaa aggaggaggagatctggcagggagagcgtcagagaggcggtctgcactctgctggcctac ggttacagcttggagcccctcaaccaggaacgcaccacattatcaaacacatgtctcttc tctgctgagaagtgcagagtgtttcgaccagataaatcatactctgtgacacgggggaag tggtactttgaacttgaaatagtgacagctgggaacatgcgagtgggctgggcccgacca ggctgcactccagataaagagctcggctcagatgaccaggcttacgtcttcgatggattt gaggctcagtggtaccatcagggcgttgagcccctggggcggcggtggcagagaggcgat gtggcgggctgcttggtggacgtggctgaacgcaccatgattgtcacgctcaatggagag gtgctgtttaatgacagaggatcagagctggctgccaaggactttgatattggagacggc ctgttgcctatcgtcagtgttggagtgaaccagatgggaaggctgaacctgggccaccag gtgagctctctgcagtacttcacagtgtgtggccagcaggagggctatgaaccctttgct gtcaacatggccagagacccagctatgtggatgagttggaaacagcctcagtttacctcc ataatgcctgatgatcaaaacctccaggtcagcagagtcagcggctcaaaggattcctta tccagtctgagggtttctcagcggttgtttgcacaccacggtggtggcagtgagatgggc ttttaccggctcagcatgtccatccagtgtgaagccatcctcactagacctgcgggaggc gtgcttcctgtggcctccagctctctctcgccaggaaggaaagagcaggaggaggtggac tctgactttgaagtgctgatgaagtcagcccacagctttgctggctcaagagatgagctc aaccataaggatcatagtcacgacaaaacatcacgattgaaacaccggttcatgctcaag aggacaaaaccagagctaatcagcaccaactcatctgcacggcttctagaagatgttgtt gtcgacaaggatagctatgatcaccttctccagagctccagatatcactactcggtgagg gttcttccaggccaggagccgtttaatgtgtgggcaggctgggtgacctctgacttccat caacaagacatgacctttgaccctgacagcgtcctcactgtcactgttacccttggagac gacagtggaaaggttcaggagagcgtaaagcggtgtaactgttacatggtgtgtgctgga gacgcaacaggcctgtcgcagagtcgcagaagtacgggtttggaaattggctgtttagtt gacacagctactgggctgctcaccttcacctccagtggagtggagatggccaccttctac caagttgaagctggtacaaagctgtttccggctgtttttgtcaagcccactacgagccac atgtttcagtttgagatggggagcataaagaatgtgatgccactgtcagcaggtttgctt cgcagtcaaagaagaaatgcaacccctcagtgtcttccaaggcttcaggtccagaatctc aacccagtttcatggatcagagtaccagcctgtgcattaaaggtgatggtggatcggcca gatgagcgccacggctggagagtccaatgccatgagcccctacaagtcatgacccttcag attcctgatgaaaacaggtctgttaacattttggagctctcggaacttgatgacctcttg acctttcaccgccacactctcctgctctactgctctttatgcgccctcggaaacaccaga gtttgtcacgccctctgcagtcacgtggaccaatcgcagatgcttcatgccattcagaac ccccacctccctggtccccttcgctctgcattttatcagctcctgactcaggttcacctc agcagccacaccacagcatgtcacatgatgaaccacgaatatattgtgcctatgactgac cagacaagagaaatcaccctgtatcccagccctgctcatggtgttaacggcgagaatggt ctacctccagaaggcatttccaatactaggctcagcacatccctgaaaccacagatgcat ttctcatctccgtgttttgtcagaagtgatgagatggaaggaggtggtacaggggacata gcccgcacagacagcccagaaatccctctggacatgttgaagaacctgacggtggagatg ctgactgctggagtatgggctgtgggtcagggtgtgagggatcctgtaggaggcagcatt gagcttctgctggttcccctaattagactgttctacaccctactggttatgggggtgttt ggggatgaggacctggggaaggttctgagactgatagagccgggagtcttctccttagat gccggaaccatcgagaaggaagaggaggaggaggaagaagaagttagtgatgatgaaaaa gaatgcaatggaggcaacaaaaaagaagattaccccttgaaacaaggacttcttcaaatg aagcttcctgaagccgtcaaacttgagctctgccatctgctgtcctacctgtgtgactgc caggtgcgccacagggtagaagctgtggttgcgttctctgacaactttgtgggtcagctg caggagaaccaacgctttcgctacaaccaggtcatgcaagcactcaacatgtctgccgcg ctcactgcccgcaagaccaaggagttccgttcacctccacaggagcagatcaacatgctg ctgcgctttagagaggatgagcagcaggacaactgtccatgtccagtggaagtccaacag ctcctccatgactttcatcaccttctcagcacacactgtggcattgagttggacagtgac acagaggacgaagaggatgcagagacgtctcttaaggaccaactcctcagtctagtagcg agagtcattggactgatgaagaccccaatacaagtggaagggagtagaccacagagcacc agtaagtgcatcgattccctcaaaacgctgatctccgagacgatggtgcgttgggctcag gagactgagatggaggaccctgaactggttagggttgtcttctcactgctgcaccgccag tatcagggccttgggggccaaatggcaggacacctctgcagagcctatacgatcagccag gcgtcggtagaagacaccatggctcttctctcctccctgagccaaatccgctccctcctc agtgtccgcatgggaaaagaagaggagaggctgatgatcaggagactaggagacatcatg aataataaagtcttctaccagcaccctaacctaatgagggcattggggatacatgagacc gtgatggaggtgatggtcaatgttcttggggaaggggaatcaaaggagattacctttcca aagatggtggccagctgttgtcgattcctgtgttatttttgccgcatcagccgtcataat cagggagccctgtttgaccacctgagttatctgctggaaaacagcagtgttggtctagcg tcaccatccatgcgtggagccactcctctggatgtggcagcagcctctgttatggacaac aatgaactggccttagcgctgagggaaccgaacctggagacggtggttcagtaccttgct ggctgcggtctccagagctgtccaatgctcgtggctaaaggctatcctgatattggatgg aaccctgtggagggcgagcgttacctcaattttttacgttttgctgtcttctgcaatggc gagagcgtagaggagaacgcttacgtggtgttgaggttgctgattcgtcggcctgagtgt tttggccctgccctgcgaggcgatgagggaaatggcctcttggcagccatgaaggaagcc atccagatctcagaggacccttctatggacggacctcgcaccacccaccagtccaacaga acactagacgttgtccaggacaatgatgacgacctcattcacatggggcacgccatcatg accttctactcggcccttatcgacatgctgggccgctgcgctccagaaatgcatttgatt catcaaggcaaaggagaagccatccggatcagagccattctgagatcgctcgtccccatt caggaccttgagggagtcatcagcatctcctttcaaatcccctcagtgtctcaagatggt ctggcggttgagcctgaccagtctacagtgttctgcccagaccacaaggcagcagtgctt cttttcctggaccgggtttacggcattgagaaccagaactttctcctccacctactagaa gttggctttctgcctgacctccaagcagcggtctctcttgacactgctgaattaggatcc accgatatggccctggccctcaacagatatttatgcacatctgttcttcccctgctcaca aagtgttcagcgctgctttgccctttagaggaccatgcttcgctggtggattctctaatc caggccatttacaacctgtccagggctctcagcttgaccaaggctcaaagagacactatt gaagaatgtttgctagctgtgtgcagtgaactccaaccatctatggtgcagcctcttctt cgacgtcttgtcttcgatgttcctcatctcacagaaaacagcaagatgcctttaaagctc ttgaccggtcactacgagcagaggtggaagtattactcactagctggagagccgggtgac cacggtttggcctctgaagaggagctccacctgtccagaaagttgttctggggcgtgttt aatgccctggcgaagaaggcctacgaggctcagttgttcaggctgtctgtccagtgcctg gctgcagtggccatggctctgccgcctgaccacatggactcaagctgtgtgtcccacacg gagagaaacgcctcgatggacacagaaggacactttgacccccggcctgtagatacctcc agtgtgtcagtgccagagagactggagtttgtagttaacaagtatgcagagcatactcac gagaagtggtcactggacaagtttgccaatggctgggttcatggggagcagctctgtgag aacaccaaggttcaccctctcctaaagccatacagggctgtggctgagaaggagaaggag gcataccgctgggcaattaaagaaacactaaagagcatgctggccttcggatggaccatc aagagaaccaaagaaggagatgcattcggcccgcagacctgtacacgcactgtgtcccag tctggacagctgtcttttgaaggagcatcgaccttcagccccaaacctatggacatgagc agcatcaccttatcatgggaccagtgtgctatggctgaacagttggctgaaaactaccac aacgcctgggctaagaggaagaaatgtgaacttgagagtaaaggtaggggtggccactca atgctggcaccttacgacaccctgactgccaaggagaagagcaaattcagagaaagagca aaggatatcctcaagttccttcagctcaatggctacacagtgtggagggatcggaagacg gtggagatagacttcccagccacggccaactgctttggctacactctccttcagcggctg ctgtctcacacagaggacgcccaagagcacatcttggagctggccagaggacagatgtct aaaggagagaactctccacaccagcaagcaattcatttttttcccaaggttatccttcct cttttggaacaatttgtgaagagccactgtctgtattttctgtccacttctctctgctcg agaagctatgcgacaaaaaaggaaaaggagatgattgcgagcctcttttgtaagctagca gctctggtaagacacaggatttcactctttggaaacgaggtctcatcagttgcaagctgc ctccatgttttgtctcgggcgctggatgccagggcattgatgaatttagccccggagtcc atccaagcatctctgcattcattctttgaggccgccgccactgatctggagatgactgtg gaaaacctgtctgtgactttggtctgtttacctcagagtaggaatcaatcggctagagga gtagccaaggttctcggcttcacaaccgcagttctccttcccacactcacttccctcttt cagcatctcggcaaccaaaactatggcgtggacctgctggtggggagtatccagctgtcc tgttacaggatcctcaacagcctcctcgctcttggcaccagcagcagcatctacatggag gggcagaggccagcagcaggtgcttgtcttgcagccttggctgggacttttcctgtgtgc ttcctggagccatccttaaaccaagacaacccatactccatctacaacagcatgagtgct gctcaaagagaagacctggggctgccagatcaggtggaggacatgtgtcccctcctgccc tctctggaacaggctctgggggaagtggagaagttggcaggcgctggtgctggaactcgc caggcccactacatccaggtcacggaggtcactttgcctatgctgtgcagctacgtgtcc cgctggtggtactggggccccgagggccagccagacggcccaatctgcacatctgtcaca cctcaacatgcgagtgaccttcttggccacatcctccgtatcatccacaaccatgtggga gctagccagggagattggatgaaagagctggcagttttttcccagccgattacttgtaaa gccggcactgagctgttaaacagccacttcctgccactgatggagaagttgaggaagagg gccaagtgtgtgctactggaggaggagcagatgaaagcagaagggtgcgatacctccgaa gcagagttgcagatacaggagaagttcactgtgctggtgcgagacctgtacgccttctat ccactcctcatcccatttgtggattcgaatcgagccagctggctgaaagatttgaaccct gacgctgagcagctgttcagcatggtggcagaggtctttacattctgggccaaatctcat aatttcaagtgggaggaacagaactttgtggttcaaaatgaaatcaacaacttggctttc ttggtcaacaccaacaaaatgtccaaggtcagccatattcacccgttgttcgaccatgag cagaggatgatgaagaggaagggggatcgttattccactcacacctctctcattgtggcc tccatgaagagactgctccctgtgggactcagggtttgttttccaagcgactacagcctc atcatgttagcgaagagcggctttgctcagaagaacactcgggatgagattcgagaaaac atttccaattgtcttataaatcttcagtatcaggcatcagactgtttgcagcaggaaacc cttcatgcagaacaccggagccagctcggggtcttccccgacgcccaacagactgtaaac aggattctggaagtagctcaagtcctttactacctggatcaggtggagcatccgcagaga agtaaaaaacctgcgtggcacaaagtcttatccaaacaaaggaaacgagcagtggtggcc tgcctgaggatggctcccctctacaacttacccaggcacagagctgtcaacctgttcctc caaggctacaataaatcctggatatcagctgaggaccacaactttgaggagaagcttgtg gaggatttggctaagggaggagtgacggagctgtttggaggtgacaaagagcgaataaag aatgtggaagaaagtgacaaaccaatcgatcccctcctccaactcattacacacttcagt cgaagcgcgctgatggaaaggaataagcttgaaaatgacggcctctataagtcctacgct gccataatggccaagagctgccacagagaggacgatgatgatgaagaacaggaagtggaa agctttgaagaaaaggagatggagaagcagaagttgctgtaccagcaggcccggctgcat cgccgtggagcttctgagatggtgctgcaaaccatcagttccagcaaaggggccatgggc tccatgatcgccccgacattaaagctgggtatcgctgtgctcaacggaggcaatgccact gttcaacagaggatgctggattatctgagagagaaacaagacgttggcttcttccagagc atggctggactcatgcggtcgtgtagtgttctggacctgaatgcattcgagaggcagaac aaagctgaaggattaggcatggccaaggatgagacctcaggagagaaggtgatgcctgac aaagacgtcacctgtgacttattccggttcctacagctgctttgtgaaggacacaactca gatttccagaattacttgagaacacaaacaggcaacaacaccactgtcaacatcataata accactgtggactatttactgagagtacaggagtcaatcagtgacttctactggtactac tcggggaaggatgtgattgatgcacacggacaacaaaacttctccaaggccatcgaagtg gccaaacaggtcttcaacacactcactgagtacatacagggcccatgcagtggaaaccaa caaagcctcgctcacagtcgcctgtgggacgccgttgtgggtttcctccatgtctttgct cacatgcagatgaagctctctcaggattcaagccaaattgagcttctgaaagagctcatg gatttacaaaaggacatggtggtcttcctgctttccatgttagaaggtactgtcgttaat ggaactatcggaaagcagatggtggatatgttggtggaatcatccggcaatgtgaagatg attctcaagttttttgacattttcctcaaacttaaagacctcacctcctcggatgccttc aaagagtacgacccggatcataagggctgcatctccaggaaggacttccagaaagcgatg gaaaactgcaagcgtttctcccaatctgagattcacttcctcctctcctgcatgaagaca aacgacagtgacgttgtggattacgaggcctttgtggatcgcttccacgagcctgccaaa gacatcggcttcagcttcgccgtcctcctcaccaatttgtccgaacacatgcccaacgat tccagactgaaggcattcttggaactggcagagtgcgtcttgacgtacttccagccccat ctcggacgtattgagatcctcggcggcgggaagcgcattgagcgcgtctactttgagatc agtgaatccagccgtacgcagtgggagaagccgcaggtcaaggagtccaagaggcagttc atttttgatgtaatcactgaggggggagagaaggagaaaatggagatgtttgtcaatttc tgcgaggacaccatctttgagatgcagctggcggcccagatatccggctctgacactgga gagcggtgtgctgataaaggagcagaagaaaagagcgaagaggaagatgtgggcaacgga ggaaggtttttcccgcatcattggttgttattgctcctatctttactttctgtcaaaaac ctgaagacggtgatgaagatgaccctgaaggatatcttcatgtcagcggttctcctcttc agattcattttaatggctcaggtccggtgtattcgcgtcgtaattggcggcgtctcgtat gtactgtacatagccttcatcagtggtgggctcatcgagggagccaagaggatgagggta tcggacttgctcggctgtgtccttgagccaactcttgatgaggtcacggaggtgccaagt ggtgtggctcggctcaggaaggactctgccagtttctcttcccaaagagaattgagggag atggggcatgtggcagctgtgacctcccccagggagatggatgccctgtcagacatattt ggcctcaaagtgaagaaggagggaggtcaatacagacttataacacaagacctcactgca agtttgactcatctgttcaacgcatcctccaaaacgattgcctctgctgatgtttctgag acgcatcaagagacggcccactctgccacagaggaaaaaacaagagatgagacaatgctt gaattacagaatacaaatttttgcagagggaaggaaactgagaagaaaactgggaaagag aaagcggaggcaagatggaaagttaagggatataataagtcagaggaatcagagagccaa cactctgccttatgggagaaaataatcactcataacaaaagcctgctgaattactttgca agaaagttttacagtatgcgcttattggctctgtttgtcgcctttgcaatcaacttcatc ctcctcttctacaaggtaagagtagcgtcgttgcctgcatcacaagaagaggaggccgtc gtcacatctgttaacagtgatggaccggactctgccgctaacgacaacaagggcagagat tattttgtgctggaggaaagcagtggatacatggaaccgtcgctccatttcctggccgta gctcacacagtcatctccttctgttgtattatcgggtactactgcctcaaggtgccattg gtgatcttcaaacgggagaaggaagtggcacggaagctggagtttgacgggctgtatgtg atcgagcagccgcctgaggaggacatcaaagggcaatgggaccgactggtcatcaacacg ccatcatttccaagtaattactgggataaatttgtgaagcgaaaggtgatggataagtat ggtgacttttacggctgcgagaagattagtgaactcctcggtttggaccgagccggatta gacttcagctcggggagaaacgagagaaggagactcaaaagacaagcttcctggagtgcc ctatttaactccattgacatcaagtaccaggtctggaaactaggagttgtgttcactgat aattccttcttgtacttggcctggtacatggtcatgtccattctgggtcattataacaac ttcttcttcgccgcccaccttttggacatcgccatgggctttaagacacttcgtaccatc ctttcctctgtcacacacaatggaaaacagttggccctcacggtgggcctgttggcggtt gtggtgtatctctacaccgttgtggccttcaacttcttcaggaagttttacaacaagagt gacgacatggacacgcgagacatgaagtgcaatgacatgcttacttgctacatgttccac atgtatgtgggcgtgcgtgcgggcgggggcatcggtgacgagatcgaggaccccgccgga gacgactttgaggtggaacgcatcgtcttcgacatcacgtttttcttctttgtcattgtc atcctcctggccatcatccagggcttgataattgatgcctttggggagcttcgtgaccag caggagcaggtgaaagaggatatggagaccaagtgtttcgtatgtggaataggaagcgag tactttgatacggtccctcatggcttcgagactcacactctgcaggagcacaacttggcc aactatctattttttctgatgtaccttattaacaaggatgaaactgaacacacagggcag gaatcctatgtgtggaaaatgtaccaggagcgctgctgggaattcttccctgtgggagac tgtttccgtaagcaatacgaggatcaactgggatga

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