Clinocottus analis (woolly sculpin): 137794427 Help Entry 137794427         CDS       T10471                                  Symbol obscna Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism cana  Clinocottus analis (woolly sculpin) Pathway cana04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cana00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     137794427 (obscna)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cana01001]     137794427 (obscna)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cana04131]     137794427 (obscna) Enzymes [BR:cana01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      137794427 (obscna) Protein kinases [BR:cana01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    137794427 (obscna) Membrane trafficking [BR:cana04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     137794427 (obscna) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Ig_4 Izumo-Ig SOS1_NGEF_PH C1-set RhoGEF C2-set_2 ABC1 fn3 PH Kdo Kinase-like IQ RHG20_PH IQ_SEC7_PH Motif Other DBs NCBI-GeneID:  137794427 NCBI-ProteinID:  XP_068447260 LinkDB All DBs Position Unknown AA seq 6274 aa AA seqDB search MGDNIPGGIVAAAKNRLQVVKGLEDVEVSECEICSFEVTLNLAYVEGLWSRDGMPLKSKP NCRISTHGKKHSLLLNRVALGDAGLFAFQAKGIQTSGRLSVTARDIYIMKELEDVDTMER QPVNFLCEVNQVDLDGRWYRDDGRIRPGDNIKIRQQGKTHSLFFKSVRPQHAGEIRFTAE RVSSYATLTVKELPVQIVRPLRVKIAMYRHRGLLECQVSRTNAQVRWYKNRKELLPSKKY QLISQDVYRQLTIDNVCSSDEDTYTCDAGDDNTSCQLLVEEQAIKIVRGMSTVEVMEPEP ALFQVETSLKSGRPPRWTLNGEVLEPCAAVNINREGTLHSLCLTSTESSMSGSMVFVAGK SRSTAQLIVKERPLEVARHLDDVQAKENSSVTLSCAFVPSPRLVRWFKGRTNLKTSNKYS MKREGKRAQLTIHGLIGMDAGQYRCMAGGSQSTAQVQVEVRTLKLVKHLEPKEVEEDGLA TFSCELNYVVANVEWLLNNVRIYCNAIYRIQHMGTMHSLTFKKLRPQQSRVTFKTGLLAE TTTLNVKERPAVFLRSLEDAVGEEQGNVRLQCEISKETVTPVWKKDGMVLTADDKHELLQ CGKSMALIIHSLSKDDAGQYTCDLGTSQSKAKVSVHDLHITISQRMKTTSVLEGENCTFD CHLSHDVEDEPSWMINGQVAVTNSRIQVINNGRNYKMTIKDAILTDAGDVVFTIKDLSCR TMLFVKEKPVHIFRELLNVKAVLGEDAELSCEITKPEVPIRWLKNGHLIRQGPKYEMTVE KNLARLVIKNSIIKDSGEYCCEADGIASRAKLDIRELQHTFAIELRDTRAEEKGKVTMEC ETRRPAKRVTWLKGMVELRSGRKYVIRQKGVVLSLTITSLDKSDTDIYTCDVGTMQSRAQ LTVQGEKVLILDELEDVECLEGDTVTFRCRICPSDYIGIKWYLDETLLYTNELNEIQMVS GGYHTLTFRQLARKDTGTISFAAGDKRSYASLLVRERRPTIIKSLEDCEAFEGGGLVLSC LASKPCHILWYKDGCLMWNSSRYFASRSGCEARLTIREVSNSDAGVYECSAGSVTTRAVV TVKAIPAEFTQSLKSVEAKEGETVTLTCEYSLPGVQVHWKRGFESIRSGDKYLMKQRKTI NSLTIKALKPEDSGEYTCQCRDHHTAASLKVHAIPITFVQQLKNMQAEEGSNVLLRCELS KPGIPVEWSKGHELLKNGVKYQIRKRETTLELLIWKPVSEDTGVYSCLCADQVTTSTVKI TALPIAFKQKLRNVLIEEGSTATLRCELSKSGHTVEWRKSGNELIKNGEKYHMRQREVLI ELRIFDVTLEDSDIYTCICGSIETTATLTVNALPVTFKQKLKNFQVEEGHTVTLDCEISK AGVPVEWRLNGELLGNGEKYQIKQRGSALELIIRDAEPEDSGVYTCVCREQRTKATVKVI AVPATFKVSLKNLEAEEGNSVTLRCELSKKEVLVQWQRDTQVISEQTYRGKYQTALEGKM AQMTILNVQPEDAGKYSCITGDQKTTAEVKVKQLPVTFKRQIQHLELKEGDSGVFCCELS KPGAPVEWRKGRAILKPGDKYQMKQEGPFTKLVVNNVEQSDAGKYICKTKDSQSAAELTV QDLPASFKMPLVNQEVTEGNSMVLRCELNKPAPSVEWRRGGALLKNGDKYQMRKKDLLVE MKISDLNLDDAGDYICICGEESTKSRIIVNERPIQFLQELKNIQVQEGNGVALCCELSKP GTPVQWKKGNNALTNGEKYQMKQSGSTLELLIRKSQPEDSGTYSCVCDDITTTATIIITA IPVTFKQKLKNQEVVEEGSVTLRCELSKPGVPVEWRKDAQLLKEGDKYQMKQEGRMAELL IRNLILTDLGEYSCFVGTVVTSADIKVRAIPVTFKQEVDDLDVKEGDSGVLCCELSKPGA PVEWRKGRVVLKPGYKYEMKQEGRLTKLIINNTEESDTGKYTCKTTDTQSTAELTVKAPP ITFKTKLRNQQVEEENSVTLNCELSKPGLAVEWTKGQEVLKNNFKYQIKNRNSSMELTIK NAQLEDSGLYSCVYRDVKTTANITITLIPLTFKMGLKNQEAPEGGNVSLRCELSRAGVPV QWWKADDQLHHGGRYQMTLKGKTAEMHIKNIQPEDVGEYSCVLGEQKTTAEVNVRAAASV FFEKELENQAVMEGKPVLLSCEVSSATVPVTWKKDNTLVEEGGHCILKKKGPTHTLEIKK LNLEDAGEYCCISRGKKTTAKLIVRERVRIVKELQGITVTAGEDAVFVCELSHADVSEGV WWLGSSPLQKNEMNQMSWQGRHHQLVLTMTTPEETGIVAFVVGEERTSARLLVIPKAKVV FEEKPKDTVIMEGETATLSCTTSDFTSPVTWRRNHIPLQNGDKYEICKKGKVNLLLIHDV DPLDTGTYYCDTGDVQSSVKLTVTELPPFFQEELQSVDVEEGGSASLYCELSKLGVPIQW LKNRLPLRAGRKYEIRQDGCLLQLNIKDLKLEDSGNYTCQAGSAETTATVSVKELPPFFK KELRSVEAEEGGTASLCCELSKAGVSVQWKKNRLPLRFTGKYEMKQDGCLLQLHINDLKP EDRGSYTCQTESAETTATVSVKELPAFFKEELQNVKAKEGGTASLCCELSKPDVPVQWKK NKLPLKAGRKYEMKQDECLLQLHIKELKPEDSGSYSCQAQSAETTATVSVKELPPFFKEE LQNMKVEEGGTASLYCELSKPDVSVQWKKNRVPLTASRKYEMKQDGCLLQLHIKDLKPED NGSYTCQAGSADTTATVSVKELPPFFNKDLVSVEAEEGRTASLCCELSKPGVLVQWRKNR LPLRASRKYEMKQDGCLLQLHIKDLKPEDSGSYTCQAESAETTATLAVKELIPFFNKELQ SVEAEEGGTTSLCCELSKAGVSVQWKKNRLPLRANRKYEMKQDGCLLQLHIKDLKPEDSG NYTCHAESAETTATVTVKELIPFFKKELQSVEAEEGGTTSLCCELSKAGVSVQWKKNRLP LRANRKYDMKQDGCLLQLHIKDLKPEDSGNYTCHAESAETTATVTVKELVPFFTKELQTV EAKEGGTTSLCCELSKAGVSVQWKKNNLPLRANKKYEMKQDGCLLQLHIKDLKSEDSGSY TCQAESAETTATVSVNELPLFFKEDLESVEAEEGGTASLYCELSKAGVSIQWKKNRLPLR ANRKYEMKQDGCLLQLHIKDLKPDDSGSYTCQAESAETTASVSVNELPPSFKEDLESVEA EEGGTASLYCKLSKPGESVQWRKNRVPLIASRKYEIKQDGCLHQLHIKELKPEDSDSYTC QAGSAETTASVSVKALQPTPPKVEPSSTILPQAKGTVSKTTTPLDQKPGLQEPKPVPPEP KKRMNRKASTTSLEKDVEQLFDQKQGIQPARSTEKDFGAKNETQLVRPKEKDSETVKKVD KSIRLLGKEDEVDMQVEETARPLETEKDIIMEKRKPGRNSEQFVNVDHNASQPNRVPGNT VFEQKKKENEVEHSLKHTGNALEKTSEVERKESHPEKVQWKNNEDETQLVKPSERFIGNI TTQEEKSTVKEGKVEEGEPFKPPLRSKAKVTNVKELPKEIEKIIVQSVKPTVKDSDGDHV KMHVSTEAEREKKPQKVVPSVNHLDKQSVEQPVKTLEKEAAFSPPKPPVRIKSKVKGSIE RQSSRDTETDQEDQQMTKVLVKTMEAQPIKQSIGSLKKEVEEKPRIQRKLSLTSDTEIIE KMKKPVKAAEDANIKQVIKQPVKPMRKEPGLDQEMKLAVEPMSQQQTPKTDIPLLYISED ETFSEALTDITSNHSNVQPPASSVERLTQPATLPPIIVPQKVQPPNEASPEMDISVEDEP EMQEAAVRIQAAFKGYKTRREMRPVFKEVFKNQSADLHGTVTLVCIVEGKPSTARWLRNG QQIINDQRCCVQTTENGVCTLVIKDLTIIDSGVYTCEAVNKFGMTSYNGNVTVGQPQKPA PIHPPLATITPLQLAPLQPGAQAKPQTQDLPQTHTQMPTSASDSANYVENVSVSLWETYN LTEQDTQMASLQERRGSSLIAASSMSSPSDYDTAPDMMEPDGTGPAVPREVLKATDQVLP NDDKEQMAPPQPAKNLLKVKGAHDGRLRTPSPKHHRAHTPLTSTISGSESEGEEDRRETF EMYVACADCSPSIENKDSFVLKEGQFVEVLDSVHPDRWLVRTKPTKTNLARQGWVCPAYL EKKRKEIFPQLRAPQEDLDGIGSTGEEYRRALSQLIQGLIDGEEEFVKEMKMFTSHQLNY LDSSRHVPINILNQKEIIFRNVKDIVFLHERSLLPGLRECATDDDVAMHLIKYAEVFEKY LHYMVGQAQAEACVTDKAVQQYFKELPESGKSDAPVMDVLTFLQRPVERIQTYQALLKEL IKNKAKSGQSCCLLEDTFSMVSCLPWRSDNLHQVSLIENYPAPLIALGEPVRQGVFTVWE ESPEIKTAARGHQRQVFLFKECIVLCKLKRDTYTFKNKMKLNDVEIKETVGGDEKSWGLW HEHRGSVRRYTLQGRSTLVKLSWLKDLKELQQRSSLPTNNPPVFESLLSDCTTKMGQTIK LTCKVTGSPKPLVSWLKDGLPLEDDPRHIITADRSGICSLILDSMTAEDSGQYACYATSS MGSAGTLAKVVVCAPPRFVSRLESACLIDGEDIQFTCSTLTAPLPRIRWLKDGRELTDQQ KYFILNDARSGILCLTIIRATEADIGQYECELLNEFGCIKCKAGLCPAYVPTIDIEDDQP QDLPPKDADSEGWSTAFVKKWLQTDFSPTSIAKMLFPPGHPEQAECSPEEAVPASISMDQ VVQQPLCYVEEEEEIYISEQMQEITDTPPSIHVPTEDMCVEPGTPATFTAIVTGRPTPTI QWYKDGEELAANDNVEISQHGARCSVTIVCPEGEDSGIYTCFTYNDSGHASCQSELTVEE GPLEYQEREVELGKRRKLFSVYDVHEEIGRGTFGVVKRVVHRRTGEVFAAKFLPLRSSTR TRSFQERDLLSRLAHPRVACLLDFFCTRRTLVLITEICCSHGLLDHLLLKGSVAEKEIQL YIQQILEGVGHIHSMNMLHLDIKPDNILMVYPPRDEIKICDFGFCQEIDTSRHQYSMFGT PEFVAPEIVHQEPVTVATDIWSVGVIAYICLVCRCPFVGETDRATLLRVEEGTLNWDSTD VTNRSPEAQNFLHMLLQPDPEKRPSAFECLSHEWLQDEHAGEDTDEINTKTLKIFISKRK WQRSLTCIGSVLTLRHIPELLDAPLRDTAVTVPREPQEHSSTSPSSGSSSEYDEADSLDF FQYCSPTEEEEDTEEEYDPLTERALIPETLAKLHLDAEEEMTLEEEEDGELGGRRSVLER SMSRQSVGSSDVSGQLTPQRERRLSSSQSLYLSDGDEGSGSDGGRIPRGSVIRSTFYNTS HQLSPMSARHMTLRDKFQAKKQERGRKPLRRSFSGRLNEPLIEYVEDETETNRGQRRGSV QPTIQKSCSFDSGVGLTHANVPPHRRSRSLDEYSRRSPSSPKRTMSGEEEGSQSLKEDLT DDEVAGRNFLAIPSPQRPTRRRGSVAPIQGAGMLGGSSVPSSTLARGRMSPRLDQEQAAG NTFAGSQGSLTESSILEHGGSESSSRLGSYEELSHGHLRGRTRSGESEGYDDQGEPRILA SSCSFQEVKPRSLVPKAPPRNRTRSNPNLSATSRGQPGTSLTSSTSPSLSSLQAPDRPPR AKDKKEGCGLQRHASAPALEVLEARPPTGKSPKLGLMKIFRRQSWTGHSYSQLDSTELGP TLGEIMMPDTPTMSLRKKMRASASSLTKLFTRSSSKEDVSKGGPIVKGTSPIPPERQHRT AESGKKRTSKLLPSFKIPAFKKSKDFLVRPNKAEVLQLDGGGVLLVWKPVQSSDPVTYCV QYCTDGADWTVLSDEVTESCFVVKDLPKGASYAFRVGCITKTGAGPFSDASASAVMATHP EEIHIPLIQTESLGSKGTGSERQNYNFLSEINRGRFSVVSMCRDAETSQVFVAKITPYQA EQRQLVLREYQLLKRLHHPHLVQLHTAYFTSCYLVLVEEFCPGKELLYSLASRDLYAETH VGELLVQILSAVDYLHSRRVVHLDLKSDNMLVDDSNHLKIVDLGSAQSFTPGQPLNIEHI HGLSESKDCRSKVYIVLPKAPEILEGQGVGPETDVWAIGVLSFIMLSADSPFHAEHGWEQ DRNIKKGKIQFGRCYPGLSEGALNFMKSSMNNKSWGRPTAAECLQNPWLRAHRAPHKGRQ SKVCFSTDKLKDYLKQKEEKRDQVRTKLQGPFFQ NT seq 18825 nt NT seq  +upstreamnt  +downstreamnt atgggagacaatatacctggaggaatagtagctgctgcaaagaaccgtctgcaggtggtg aagggcttggaggatgtggaggtgtctgagtgtgagatctgctcctttgaagtgaccctc aacctggcctatgtcgagggtctatggtccagagacgggatgccgcttaagtccaagccc aactgtcgcatcagcacacatgggaagaaacactccctcctactgaacagggtggctctg ggagacgcagggctgttcgcttttcaggccaaaggcattcagacctctggcagactcagt gtcacagctagggacatctacataatgaaggagctggaggatgttgacacgatggagcgt caacccgtgaacttcctgtgtgaggtcaaccaagtggatttggatggtcggtggtataga gatgatggccgaattcggcctggagacaatatcaagatcagacaacagggtaaaactcac tccctgttcttcaagtcagtcaggccacagcatgctggagagattagattcactgcagag cgtgtatcatcctatgcaactctcacagtgaaagagctcccagtccaaatagtgcgtcct ctaagggtcaagatagctatgtatcgccaccggggtctgctggagtgccaggtgtcacgg accaatgctcaggtcaggtggtacaagaacaggaaggagctcctgcccagcaagaagtac caactgatcagccaagatgtctacaggcagctgaccatcgacaacgtctgctcttcagat gaggacacctacacctgtgatgcaggagatgacaacacctcttgtcagcttctggtggag gagcaggctatcaaaatagtgcgagggatgagcacagtggaggtgatggagccagagcca gcgctgttccaggtggagactagtctgaaatcagggaggcctccccgctggaccctgaac ggggaggtgctggagccatgcgcagcagtgaacatcaacagggagggcacgctccacagc ctctgtctcacctccacagagagctccatgtctgggtccatggtctttgtagctggcaag agtcgttccactgctcagctaattgtcaaagagcgacctcttgaggttgcccgccacttg gacgacgtacaggcgaaggagaacagctctgtgactctgagctgtgcgttcgtgccctct cccagactggtgcggtggtttaaaggccgtacaaatctgaagacctcgaacaagtacagc atgaaacgggaagggaaacgagcccagctgaccattcatggcttgatagggatggatgcg gggcagtaccgctgcatggctggaggttcacagagcacagcacaagttcaggtagaagtg cgaacgctaaaattggttaaacaccttgagccaaaggaagttgaggaggatggccttgcc acattttcatgtgagctcaactatgtcgttgccaatgtggagtggctcctcaacaatgtt cgcatctattgcaacgccatctacagaatccagcacatgggcacgatgcacagtctcacc tttaagaagctgcggccacagcagagcagggtcaccttcaaaacaggacttcttgcagag acaaccacgttaaatgtcaaagagcgcccagcagtgtttctgagatctctggaggatgca gtaggggaagagcaagggaatgtccgcctgcagtgtgaaatctccaaagagacagtgacc cctgtttggaagaaggatggtatggtcctgaccgctgatgataaacacgagttactccag tgtgggaagtccatggcactgatcatccattccctgagcaaggatgatgctggacagtac acttgtgacctgggcaccagccaatcaaaggccaaagtttctgtacatgacttacacatc actatttcgcaacgtatgaagacaacatctgttttggaaggtgaaaactgcacttttgat tgtcacctttctcatgacgttgaggacgagccttcctggatgatcaatggccaagtggcg gtcaccaacagccgaattcaagttatcaacaatggccgtaactataagatgaccatcaaa gatgctatactgactgatgctggagatgtggtcttcacaattaaagatctaagctgtagg accatgctttttgttaaagagaagccagtgcacatcttcagggagctattaaatgtcaag gcggtcctgggcgaggacgcagagctgagctgtgagatcaccaaaccagaagtccccatc cgttggctgaaaaatggccacttgatcagacagggccccaagtatgagatgactgtggag aagaacctggcgcgattagtcatcaagaacagcatcatcaaagactctggagagtactgc tgtgaggccgatggcattgcctcgcgtgccaagctggatatcagagaactccagcacact tttgctatcgagttaagggacacgcgagcagaggaaaagggtaaagtgaccatggagtgt gagaccaggcggccagccaaacgagtgacctggctgaagggcatggtggagctgaggtct ggcaggaagtatgtcatcaggcagaagggtgtggtgctgtccctgacgatcaccagtctg gacaaatccgacacagacatttacacctgtgatgtcggtaccatgcagagccgggcccag ctgactgtgcagggtgagaaggtgttgatcctggatgaattagaggatgttgagtgtcta gaaggtgacacagtcacgttcaggtgtcggatttgtcccagtgactacatcggaatcaag tggtacctggacgagactctgctgtacaccaatgagctcaatgagatccagatggtgtcc ggaggctaccacaccctcacatttagacagcttgctcgcaaagacacgggcactatctcg tttgcagcgggggacaaaagatcgtatgcctcactgttggttagagagaggcgtcccacc atcattaaatccctggaagactgtgaggcttttgaaggaggtggtttagttttgtcttgt ttggcctccaagccatgtcacatcctgtggtacaaagatggctgcctgatgtggaactcc tcaaggtattttgccagtcgttccggctgtgaagcccggctgacaattcgggaggtcagt aacagcgatgccggagtgtacgagtgcagtgctggatctgttacaactagggctgttgta actgtcaaagccatcccagcagagttcacccagtctttaaagtctgtggaggccaaagag ggggagaccgtgaccctgacctgtgaatactccctgcctggggtccaggtccactggaag agaggttttgaaagcattaggtctggagacaaatatctgatgaaacagaggaagacaatc aattctctgaccattaaagctctgaagcctgaggactcaggagaatatacctgtcagtgt agagatcatcacactgcagcaagcctcaaagtacacgctattcccatcacattcgtacaa cagttaaagaacatgcaagcagaggagggaagcaatgtcctactgcgctgtgaactgtct aaacctggaattccagtggagtggagtaaaggacatgagctgttgaagaatggagttaaa taccagatcaggaaaagggagaccaccttggagcttctgatctggaagcctgtttcagag gacactggggtttacagctgcctgtgtgctgatcaggtgacaacctccactgtcaaaatc acagctctcccaatagccttcaagcagaagctgaggaatgtgctgattgaggagggcagc actgcgactctacgctgtgagctgtcaaagtctggccacaccgtggagtggaggaagagc gggaatgaactcatcaagaatggagagaaataccacatgaggcagagagaagtgctaatt gaactgaggatctttgacgttacgctcgaggacagcgacatctacacgtgcatctgtggg agcatagagaccaccgcaacgctgaccgttaatgctcttcctgtcaccttcaagcagaaa ctgaagaacttccaagtggaggaaggacacaccgtcacgctggattgtgagatctctaaa gcgggagtcccagtggagtggaggcttaatggagagctgctggggaatggagagaagtac cagattaagcagaggggctcggcactcgagttgatcatcagagacgctgaaccagaggac agcggggtctacacctgtgtgtgtagagagcagaggacaaaggccactgttaaagttatt gccgttcccgccacatttaaagtaagtctgaagaacctggaggctgaagaagggaacagt gtgactttacgctgtgagctgtcaaagaaggaagtcctggtgcagtggcagagagacact caggtgatatctgagcagacatatcgggggaagtatcagacggcgctagaaggaaagatg gctcagatgaccattctcaatgtccagccagaagatgcagggaagtacagctgtatcaca ggggatcagaaaaccaccgctgaagtcaaagtgaaacagctccctgtgacattcaaacga cagatccagcatctggagttgaaggaaggtgacagtggagttttctgctgtgagctctcc aaacctggagctccagtggagtggaggaaaggcagggcgatcctaaagcctggagacaaa taccagatgaagcaggagggacctttcactaaactggtcgtcaacaacgtagagcagagc gatgctggcaaatatatctgcaagactaaagacagccaatcggctgctgagctcactgtc caagatttaccagcaagttttaagatgccactagtcaaccaggaggtgacggagggcaac agtatggttctgcgctgtgaactcaacaaaccggccccttcggtggagtggaggagagga ggagcactgctgaaaaatggagacaaatatcaaatgaggaagaaggaccttctggtggag atgaagatttcggaccttaatctggatgatgctggagattacatctgtatatgtggagaa gaaagcacaaaatctaggattattgtgaatgagcggcccatccagttccttcaagaactg aagaacattcaggtgcaggaaggcaatggagtagcactgtgctgtgagctctccaaacct ggcactccagtgcagtggaagaagggaaacaatgcgttgaccaacggagagaaataccag atgaagcaaagtggctccaccttggaactcctcatcagaaaaagccagcctgaggacagt ggcacatacagctgtgtttgtgatgacataacaactacggccaccatcatcatcactgca atcccggtaactttcaagcagaagttgaagaaccaggaagtggttgaggagggcagtgtg acactgcgctgtgagctttctaaaccaggagtcccagtggagtggaggaaagatgctcaa ctcttgaaggagggagacaaatatcagatgaaacaggaaggcaggatggccgagttgctg atcagaaatttgattctcacagatttgggggagtacagttgttttgttggtacagttgtg acttcagctgacatcaaagtaagagcaattcctgtaacatttaaacaagaggtggatgat ttggacgtgaaggaaggggacagtggagttttgtgctgtgagctctccaaacctggagct ccagtggagtggagaaaaggcagggtcgtcctcaaacctggatacaaatatgagatgaaa caggagggacgtctcactaaactgatcatcaacaacactgaggagagtgatacggggaaa tacacctgcaaaaccacagacacacaatccactgctgagctcaccgtcaaagctcctcca atcacattcaagacaaagttaaggaaccagcaggtggaggaggagaacagcgtgacgttg aactgcgagctgtcaaagcccggcctcgctgtggagtggacgaaaggacaagaggtgctg aagaataattttaagtaccagattaaaaatcgaaacagcagcatggagctgaccatcaaa aacgcgcagctggaagacagtggactttacagctgtgtctacagggacgttaagaccaca gccaacatcaccattacacttatccccctcacctttaaaatgggtctgaagaaccaggag gcccccgaaggaggcaacgtgtccctccgctgtgagctgtccagggccggggttcctgtg cagtggtggaaagcagacgaccagctccatcatgggggaagataccagatgacactgaag gggaagacagctgagatgcacatcaaaaacatccagcccgaggatgtcggggagtacagc tgtgtcttgggagagcagaagacaacggctgaagtcaacgtgagagcggcggcgtcagtg ttctttgaaaaggaacttgagaaccaagcagtgatggagggtaaacctgtgctgctgtct tgtgaagtttcaagtgctactgtccctgtcacttggaagaaagacaacactttagtggaa gaaggggggcactgcattttaaagaagaaaggccccactcacacactagagatcaagaaa cttaatctggaggatgctggggagtactgctgtatcagtagaggcaagaagaccaccgcc aagctgattgtgagggagcgcgtgcggattgtcaaagagctgcaaggtattacggtgaca gccggtgaggatgcagtgtttgtgtgtgagctgagccatgcagacgtgagtgagggtgtc tggtggctcggctccagccctctgcaaaagaacgagatgaaccagatgtcatggcagggt cgccatcaccaattggtccttaccatgacaacacctgaagagacgggcattgtggcattt gtggtcggggaggagaggacctctgcacgtctgctggttattccgaaggccaaagttgta tttgaggagaagcctaaagacaccgtaatcatggaaggagagacagccactttgtcctgc acaacctctgatttcacctcgccggttacgtggagacgcaaccacatccccctccaaaat ggtgataaatatgagatatgcaaaaagggaaaagtcaacctattgctcatccatgatgtg gatcccctggatactggcacatactactgtgatacaggagatgtgcagagtagtgtcaaa cttactgtaacagagctcccaccatttttccaagaagaactgcaaagtgtggatgtcgag gaaggtggttcagcctctctgtactgcgagctgtctaaacttggagtgccgattcaatgg ctgaagaacaggctgccactaagagccggcaggaagtacgagatcaggcaggacggctgt ctcctccagctaaacatcaaggatctcaaactggaggacagcggcaattacacatgtcaa gcaggaagtgcagagaccactgcaactgtgtcagtgaaagagctccctccattcttcaag aaagaattaagaagtgtggaggctgaagagggaggtacagcctctctgtgctgcgagctg tctaaagctggagtgtcagtacaatggaagaagaacaggctgccactaagattcacaggg aagtacgagatgaagcaggatggctgcctcctccagctgcacatcaatgatctcaagcct gaggacagaggcagctacacatgtcaaacagagagtgcagagactactgctactgtgtca gtgaaagaactcccagcttttttcaaagaggaattgcagaacgtgaaagctaaagaagga ggtacagcctccctgtgctgtgagctttctaagcctgacgtaccagtacaatggaagaag aacaagctgcctctgaaagccggcaggaaatatgagatgaaacaggatgagtgtcttctt cagctccacatcaaagaactcaaacctgaagacagtggaagctactcatgtcaagcacaa agtgcagaaaccacggctactgtgtctgtaaaagaactcccaccatttttcaaagaagaa ttgcagaacatgaaggtagaggagggaggtacagcctccctgtactgtgagctgtccaaa cctgacgtatctgtacaatggaagaagaaccgggtcccgctaacagccagcaggaagtat gagatgaaacaagatggctgcctcctccagctccacatcaaggatctcaaacctgaagac aacggcagctacacatgtcaagcaggaagtgctgacaccactgctactgtgtcggtgaaa gagctccctccattctttaataaagacttggtaagtgtggaggctgaggagggaaggaca gcctctctgtgttgtgagctgtctaagcctggagtactagtacaatggaggaagaacagg ctgccactgagagccagcagaaagtatgagatgaaacaagatggctgcctcctccagctg cacatcaaggatctcaaaccagaggacagtggcagctacacatgtcaagcagagagtgct gagaccactgctactctggcagtgaaagagcttataccattcttcaacaaagaattacaa agtgtggaggctgaggagggaggcacaacctctctgtgctgcgagctgtctaaagctgga gtgtcggtacaatggaagaagaacaggctgccactaagagcgaacaggaagtatgagatg aaacaagatggctgcctcctccagctgcacatcaaggatctcaaaccagaggacagtggc aactacacatgtcacgcagagagtgccgagaccactgctacagtgacagtgaaagagctt ataccattcttcaagaaagaattacaaagtgtggaggctgaggagggaggcacaacctct ctgtgctgcgagctgtctaaagctggagtgtcggtacaatggaagaagaacaggctgcca ctgagagcgaacaggaagtatgacatgaaacaagatggctgcctcctccagctgcacatc aaggatctcaaaccagaggacagtggcaactacacatgtcatgctgagagtgctgagacc actgctacagtgacagtgaaagaacttgtcccattcttcaccaaagaattacaaactgtg gaggctaaggagggaggcacaacctctctgtgctgcgagctgtctaaagctggagtttca gtacaatggaagaagaacaatctgccgctgagagcaaataagaaatatgagatgaagcaa gatggctgcctcctccagctgcacatcaaggatctcaaatctgaagacagtggcagctac acatgtcaagcagagagtgctgagaccactgctactgtgtcagtgaacgagctcccatta ttcttcaaggaagacttagaaagtgtggaggctgaagagggaggtacagcttctttgtac tgcgagctgtccaaagctggagtgtcaatacaatggaagaagaacaggctgccactgaga gcgaacaggaagtatgagatgaagcaagatggctgccttctccagctccacatcaaggat cttaaacccgacgacagtggcagctacacgtgtcaagcagagagtgctgagaccactgct tctgtatcagtgaacgagctcccaccatcctttaaggaagacttagaaagtgtggaggcg gaagagggaggtacagcctctttgtactgtaagctgtctaagcctggagaatcagtacaa tggaggaaaaacagggtcccactaatagccagcaggaagtatgagattaagcaggatggc tgccttcatcagctgcacattaaggagctcaaacctgaagacagtgacagctatacgtgt caagcaggaagtgcagagaccactgcttctgtgtcagtgaaagcactacaaccgactcca ccaaaggtagagccttcttcaacaatactgccacaggcaaagggcacggtttccaaaaca acaactccattggaccagaagcctggactccaagagcccaaacctgttcctccagagcca aaaaagagaatgaatagaaaagcatctactacaagtttagaaaaagatgtggagcaattg tttgaccaaaagcagggcatccaacctgctaggtctacagagaaagactttggtgcaaag aacgaaacacaactggtcaggccaaaggagaaagacagtgagacggtcaagaaagttgac aagtctataagactactggggaaggaggatgaggtagacatgcaggtggaagagacagca aggcctttggaaacagagaaagacattatcatggagaagagaaaaccagggaggaattca gagcaattcgtcaatgttgaccataatgcaagtcagccaaacagggttccaggaaacact gtgtttgaacaaaagaaaaaggaaaatgaagttgaacatagtttaaaacatacaggaaat gctttagagaaaacaagtgaagttgagaggaaggaaagccatccagaaaaagtccagtgg aagaacaatgaggatgagacacagcttgtaaaaccatcagaaaggtttattgggaatata acaacacaagaagagaagtctacagtaaaggagggaaaagtagaagaaggagaaccgttt aaaccacctctaaggtctaaagcaaaggtaacgaatgtaaaggaattaccaaaggaaatt gagaagatcattgtccaatcagtgaagcctactgtaaaggattctgacggagaccatgtg aaaatgcatgtgtccacagaggcagaaagagagaaaaagccacagaaagtagtgccatct gtaaatcatctggacaaacagtcagtagaacagcctgtgaagactttagagaaagaggct gcattttctcctccaaaaccgccggtgaggataaaaagcaaagttaaggggtcaatagaa aggcaatcatcaagggacacagagacagatcaagaggatcaacagatgacaaaagtgttg gttaaaacaatggaggctcagccaattaaacagtcaatagggtctttgaaaaaggaggtt gaagaaaaaccaagaattcagaggaaactatccttaacatcagacactgaaataatagag aaaatgaaaaaacctgtgaaagctgcggaggacgcaaacataaaacaggtgatcaaacaa ccagtaaaacccatgagaaaagagcctggactagatcaggaaatgaaactggcagtcgag ccaatgagccaacaacaaacaccaaaaacagacattcctctcctttatatttctgaagat gaaactttctcagaggctttgactgacataacttcaaaccacagcaatgtccagccgcct gcttcttctgttgagcggttgacccaacccgctactcttcctccaattattgtcccccag aaggtacaaccgccaaatgaagcatcaccagagatggacatcagcgttgaggatgaacca gaaatgcaagaggctgcagtcaggatccaagctgccttcaaaggctacaaaacccgcaga gaaatgcgacctgtctttaaagaggtgtttaagaaccagagtgcagatcttcatggtacg gtcactctagtgtgtattgtagaggggaaacccagcacagcacgctggctgagaaacggc caacaaatcatcaatgaccagcgatgctgtgttcagactacagagaacggtgtgtgcaca ctggtgattaaagacctgaccatcattgacagtggagtctatacatgtgaggctgtgaat aagtttggtatgacctcctataatggaaatgtaacagtaggacagcctcagaagcctgcc ccgattcatccgccacttgcaaccataacccctctgcaactcgccccgctgcagcctgga gcccaggccaaaccacagactcaggatctgcctcagactcatacccagatgcccacttca gcttcagattctgcaaactatgtagaaaatgtgagtgtctctctgtgggagacctacaac ctgacggagcaggacactcagatggcaagcctacaagagaggagaggatcctcactcatt gctgccagctccatgtcgagtccctcggattatgacacagctccggatatgatggagcct gatggaactggcccagctgtaccaagggaagtgctaaaagcaacagaccaagtgcttcca aatgatgataaagaacagatggctcctccacaacctgctaaaaacctactcaaggtcaaa ggggctcatgatggtagactgaggacgccatcccctaagcaccaccgcgctcacacaccc ttaactagtaccatctctggatcagagtcagaaggggaagaggatagacgagagacattt gaaatgtacgtggcttgtgcggattgtagtccaagcatcgaaaataaggacagttttgtt ctgaaggagggccagtttgtagaggtcctggactctgttcaccctgacaggtggctggtg agaaccaaacccaccaaaacaaaccttgcgagacagggatgggtgtgtccagcctacttg gagaagaagaggaaggagatcttcccgcaactgagagcacctcaagaggatcttgatgga atagggtctacaggagaagagtacaggagagctttgagccaactgatccagggcctgatt gatggagaggaggagtttgtaaaggagatgaagatgttcacctctcaccagctaaattat ttggactcgagccgccacgttcccattaacatcctcaaccagaaagaaatcattttcaga aatgtcaaggacattgtgtttctgcatgagaggtccctccttcctgggctgagagaatgt gccacagacgatgacgtggccatgcacctgatcaagtatgctgaggtctttgagaaatac cttcactacatggtgggacaagcacaagcagaggcctgcgtcactgacaaggctgtccag cagtatttcaaagagttaccggaatctgggaagtctgacgcaccggtcatggatgtcctc accttcctccagcgaccagtggaaaggattcaaacctaccaggctttactaaaggagctg atcaagaataaagccaaaagtggccagagctgctgtcttttggaggataccttctccatg gtgtcctgtctgccctggaggtctgacaacctgcaccaggtgtccctcattgagaactac ccagctcctctaatcgccctgggtgagcctgtgagacagggagtcttcacagtgtgggag gaatctccagaaataaagacggccgctagagggcatcaaagacaagtctttctctttaag gaatgcattgtactgtgtaaactgaaaagagacacctacaccttcaagaacaaaatgaag ctgaatgatgtggaaataaaggagactgtgggtggagatgaaaagtcttgggggctgtgg catgagcacaggggttcagtgcggaggtacacactgcagggccgctccacgctggtcaaa ctctcctggctcaaagacctgaaggagctccagcaacgctccagcctgcccactaacaac ccaccagtgtttgagtcactgttgtctgactgcacaactaagatgggacagacaatcaaa ctgacctgtaaggtcacgggatcacctaaaccattggttagctggctcaaagacggcctt ccactagaggacgacccccgtcacatcatcacagcagaccgctcaggcatctgcagtcta atcctggacagcatgactgcagaggactctggacagtatgcctgctatgcgaccagctcc atgggcagtgctggtactctggctaaggtcgtggtgtgcgctccacccagatttgtgagc cgactggagagtgcttgtctgatagatggagaggatatacagtttacctgctccacactt actgctcctttaccacgaatcaggtggttgaaagatggaagagagttgactgaccagcaa aaatacttcatcctgaatgatgctcgcagtggaatcttatgtttgacgatcatcagagca acagaggccgatattggacagtatgagtgtgagcttttgaatgagtttggctgcatcaag tgcaaagcagggctgtgccccgcttacgttccaaccattgacatcgaggatgaccaacca caagacttgcctcctaaagacgcggactcagagggttggtcaactgcctttgtgaagaaa tggctccagactgatttcagccccacttctattgctaagatgctcttccctcctggacac cctgaacaagctgaatgtagtcctgaagaggctgttcctgcctcaatatccatggatcag gtggtccagcagcctctgtgttacgtcgaggaggaagaggagatctacatctccgagcaa atgcaggaaattacagatactcctccctccatccatgtacccacggaggacatgtgtgta gagcctggcacaccggccacatttactgccatcgttacaggaaggcctactcctactata cagtggtacaaggatggagaggagcttgcagccaatgataatgtggagatatcacaacat ggagcccgctgctcagtgaccatagtgtgccctgagggagaggacagtggcatatacacc tgcttcacctacaatgactctggtcatgcctcatgccagtctgagctgactgtggaggaa ggtccactggagtatcaggagagagaggtggagctggggaagagaaggaagctattctcc gtctatgatgtccatgaggaaattggaaggggaaccttcggggtagtgaagcgtgtagtc cacagacgaacaggggaggtgtttgctgccaagttcctgcctctgcggagcagcactcgg acccggtccttccaggagagggacttactatcccgtttggctcaccccagagtggcctgt ctgctggacttcttttgtaccagacgcactctggtgctgatcacagaaatctgctgttct catggactgttggatcatttattattgaaaggatcagttgcagaaaaagagatccagtta tacatccagcaaatccttgaaggagttggtcacattcacagcatgaacatgctgcacctg gacattaaaccggataatatcctcatggtgtatccgcccagagatgagatcaagatctgt gactttggcttctgccaagaaatagacacatccagacaccagtacagcatgtttggtaca ccagagtttgtggccccggagattgttcaccaagaaccagtcactgtggccactgatatt tggtctgtgggtgttatagcctacatatgtttggtgtgccgatgccctttcgtgggggag actgaccgtgctacactgctaagagtggaggagggcaccctgaactgggattccactgat gtcacgaacaggagccctgaagcccagaactttctccacatgctcctacagccagatcca gagaagcgaccatctgcctttgagtgcttaagccacgaatggctccaggatgaacatgca ggtgaagatacggatgaaatcaacacaaagactttgaaaatcttcatctcaaaaaggaaa tggcagcgttctttgacttgcattgggtcagttctcacattgaggcacatccccgagctg ctggacgctcctctcagagacactgcagtgacagttccccgcgagccgcaggaacacagc agcacctctccgagcagtggctcctcttcagagtatgacgaggctgactctttggacttt ttccagtactgcagcccgactgaagaggaggaagacactgaggaggagtatgatccttta acggagcgtgcgctgatccctgagactttagccaaactccaccttgatgcagaagaggaa atgacattagaggaggaagaggatggcgagctgggaggaaggaggagtgtactcgagcga agtatgagtagacagtcggttgggtcatcagatgtatccggtcaactgacgcctcaaagg gagcgtaggttgagcagtagtcaatctctctacctctctgacggggatgagggttcaggg agtgacgggggtcgtatccctcgtggcagcgtcatccgaagcactttctacaacacctct catcagctttcacccatgtccgccagacacatgacattacgggacaaattccaggccaaa aagcaggagagaggccgcaagccactccggagaagcttttcaggacgtctaaacgagcct cttattgaatatgtggaggatgagacagagaccaatcgtggccagagacggggatctgtg cagcctacaatacagaagtcctgttcttttgacagtggtgttggactcacccacgctaat gttcccccccacaggaggagcaggtctcttgatgagtattctcggcgatctcccagttca cccaagcgcacaatgtcaggggaggaagaaggctctcaaagtctgaaggaagatctaaca gatgatgaagtggccgggagaaacttcttagctatcccgagcccacagcgacccacaaga agaagaggctctgtggctccaatacaaggcgccggcatgctgggtggatcatctgttccc tcaagtacccttgctagaggcagaatgagccccagactggatcaggagcaggcagctggc aataccttcgctggctcacaggggtctctgactgagtcgtctattttggagcatggtggc tccgagtcttcaagtagactcggctcttatgaggagctgagtcatggtcatctcagaggg agaaccagatctggagagagtgaagggtatgatgatcaaggggagcctcggattttagca tcctcatgctccttccaagaagttaaacctaggagcttggttcccaaggctccgccacgt aaccgcacccgctccaaccccaacttatccgcaaccagcagaggtcagccagggacatca cttacatcgagcactagtcccagcctctcttctctgcaggctccagacaggcctcccaga gccaaggacaagaaggagggatgtggcctccaaaggcatgcatccgctccagccctcgaa gtcctcgaagctcggccacctacaggaaagtcccccaagctgggactgatgaagatcttc cgcaggcagtcctggactggccattcatactcccagctggacagcacagagttgggaccc acattaggagagatcatgatgccagatactcccaccatgtctctgaggaagaaaatgaga gcttcagcctccagcctgaccaagctgtttaccaggtcttccagtaaggaggacgtgagt aaaggagggccaatagtaaagggaacatctcccatcccacctgaaagacagcatagaact gctgagagtggaaaaaagaggacctccaaactattgccttcttttaaaatacctgctttc aaaaagtcaaaagatttcttggtgcggcccaacaaggctgaagtcctccagttagatgga ggtggagtcctgctggtctggaaaccagtccagtccagtgaccccgtcacctactgcgtg cagtactgtacagacggtgcggactggacggtcctgtcggacgaggtgactgaaagctgc tttgtggtgaaggacttacccaaaggagcctcctatgcgtttagggtgggttgcatcacc aagacaggagcgggacctttcagcgatgcttcagcatcggctgttatggctactcatcct gaagaaattcacattcctctaatccagactgagtcactggggtcaaagggcactgggtca gaacgacagaactacaacttcctctctgagatcaacaggggccgtttcagcgtcgtcagc atgtgcagggatgctgagaccagccaagtgtttgtggccaagatcaccccttaccaggca gagcagagacagttggtgctgagggagtaccagctgctgaagaggctccatcaccctcac ctggtgcagctgcacactgcctatttcacctcctgctacttggtgttggtggaggagttc tgtcccggcaaggagctgctctacagtctggcatccagagatctgtatgcagagactcac gttggagagctgttggttcagatcctgagtgcagtcgactacctgcatagccgtcgagtc gtccacctggacctgaagtccgacaacatgctggtggacgacagcaaccacctgaagata gtcgacctgggctcggctcagtcattcacgcccggtcagcctctcaacatcgagcacatt cacggcctatcggagagcaaagactgccgcagcaaagtttatattgtccttcctaaagct ccggaaatccttgaaggtcaaggtgttggacctgaaactgatgtttgggctattggagtt ctgtccttcatcatgttgagtgccgacagcccgttccatgcagagcacggctgggagcaa gacagaaacatcaagaaagggaagatccagtttggacgctgctaccccggtttgtcagag ggagccttgaacttcatgaagagcagcatgaataacaagtcctgggggagacccactgca gccgagtgtctccagaacccatggctgcgcgcccatcgcgccccacacaaaggccgacag tccaaagtgtgcttctccacggacaagctgaaagattatctcaagcagaaggaggagaag cgagaccaggtccgcaccaagcttcaaggccccttcttccagtga

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