KEGG   Colobus angolensis palliatus (Angola colobus): 105503488
Entry
105503488         CDS       T08744                                 
Symbol
PRKCA
Name
(RefSeq) protein kinase C alpha type
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
cang  Colobus angolensis palliatus (Angola colobus)
Pathway
cang01521  EGFR tyrosine kinase inhibitor resistance
cang04010  MAPK signaling pathway
cang04012  ErbB signaling pathway
cang04014  Ras signaling pathway
cang04015  Rap1 signaling pathway
cang04020  Calcium signaling pathway
cang04066  HIF-1 signaling pathway
cang04070  Phosphatidylinositol signaling system
cang04071  Sphingolipid signaling pathway
cang04072  Phospholipase D signaling pathway
cang04082  Neuroactive ligand signaling
cang04150  mTOR signaling pathway
cang04151  PI3K-Akt signaling pathway
cang04261  Adrenergic signaling in cardiomyocytes
cang04270  Vascular smooth muscle contraction
cang04310  Wnt signaling pathway
cang04360  Axon guidance
cang04370  VEGF signaling pathway
cang04510  Focal adhesion
cang04540  Gap junction
cang04613  Neutrophil extracellular trap formation
cang04650  Natural killer cell mediated cytotoxicity
cang04664  Fc epsilon RI signaling pathway
cang04666  Fc gamma R-mediated phagocytosis
cang04670  Leukocyte transendothelial migration
cang04713  Circadian entrainment
cang04720  Long-term potentiation
cang04723  Retrograde endocannabinoid signaling
cang04724  Glutamatergic synapse
cang04725  Cholinergic synapse
cang04726  Serotonergic synapse
cang04727  GABAergic synapse
cang04728  Dopaminergic synapse
cang04730  Long-term depression
cang04750  Inflammatory mediator regulation of TRP channels
cang04911  Insulin secretion
cang04912  GnRH signaling pathway
cang04916  Melanogenesis
cang04918  Thyroid hormone synthesis
cang04919  Thyroid hormone signaling pathway
cang04921  Oxytocin signaling pathway
cang04925  Aldosterone synthesis and secretion
cang04926  Relaxin signaling pathway
cang04928  Parathyroid hormone synthesis, secretion and action
cang04929  GnRH secretion
cang04933  AGE-RAGE signaling pathway in diabetic complications
cang04935  Growth hormone synthesis, secretion and action
cang04960  Aldosterone-regulated sodium reabsorption
cang04961  Endocrine and other factor-regulated calcium reabsorption
cang04970  Salivary secretion
cang04971  Gastric acid secretion
cang04972  Pancreatic secretion
cang05017  Spinocerebellar ataxia
cang05022  Pathways of neurodegeneration - multiple diseases
cang05031  Amphetamine addiction
cang05032  Morphine addiction
cang05143  African trypanosomiasis
cang05146  Amoebiasis
cang05161  Hepatitis B
cang05163  Human cytomegalovirus infection
cang05164  Influenza A
cang05170  Human immunodeficiency virus 1 infection
cang05171  Coronavirus disease - COVID-19
cang05200  Pathways in cancer
cang05205  Proteoglycans in cancer
cang05206  MicroRNAs in cancer
cang05207  Chemical carcinogenesis - receptor activation
cang05214  Glioma
cang05223  Non-small cell lung cancer
cang05225  Hepatocellular carcinoma
cang05231  Choline metabolism in cancer
cang05415  Diabetic cardiomyopathy
cang05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cang00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105503488 (PRKCA)
   04012 ErbB signaling pathway
    105503488 (PRKCA)
   04014 Ras signaling pathway
    105503488 (PRKCA)
   04015 Rap1 signaling pathway
    105503488 (PRKCA)
   04310 Wnt signaling pathway
    105503488 (PRKCA)
   04370 VEGF signaling pathway
    105503488 (PRKCA)
   04066 HIF-1 signaling pathway
    105503488 (PRKCA)
   04020 Calcium signaling pathway
    105503488 (PRKCA)
   04070 Phosphatidylinositol signaling system
    105503488 (PRKCA)
   04072 Phospholipase D signaling pathway
    105503488 (PRKCA)
   04071 Sphingolipid signaling pathway
    105503488 (PRKCA)
   04151 PI3K-Akt signaling pathway
    105503488 (PRKCA)
   04150 mTOR signaling pathway
    105503488 (PRKCA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    105503488 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105503488 (PRKCA)
   04540 Gap junction
    105503488 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    105503488 (PRKCA)
   04650 Natural killer cell mediated cytotoxicity
    105503488 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    105503488 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    105503488 (PRKCA)
   04670 Leukocyte transendothelial migration
    105503488 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    105503488 (PRKCA)
   04929 GnRH secretion
    105503488 (PRKCA)
   04912 GnRH signaling pathway
    105503488 (PRKCA)
   04921 Oxytocin signaling pathway
    105503488 (PRKCA)
   04926 Relaxin signaling pathway
    105503488 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    105503488 (PRKCA)
   04918 Thyroid hormone synthesis
    105503488 (PRKCA)
   04919 Thyroid hormone signaling pathway
    105503488 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    105503488 (PRKCA)
   04916 Melanogenesis
    105503488 (PRKCA)
   04925 Aldosterone synthesis and secretion
    105503488 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105503488 (PRKCA)
   04270 Vascular smooth muscle contraction
    105503488 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    105503488 (PRKCA)
   04971 Gastric acid secretion
    105503488 (PRKCA)
   04972 Pancreatic secretion
    105503488 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    105503488 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    105503488 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    105503488 (PRKCA)
   04727 GABAergic synapse
    105503488 (PRKCA)
   04725 Cholinergic synapse
    105503488 (PRKCA)
   04728 Dopaminergic synapse
    105503488 (PRKCA)
   04726 Serotonergic synapse
    105503488 (PRKCA)
   04720 Long-term potentiation
    105503488 (PRKCA)
   04730 Long-term depression
    105503488 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    105503488 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105503488 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    105503488 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105503488 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105503488 (PRKCA)
   05206 MicroRNAs in cancer
    105503488 (PRKCA)
   05205 Proteoglycans in cancer
    105503488 (PRKCA)
   05207 Chemical carcinogenesis - receptor activation
    105503488 (PRKCA)
   05231 Choline metabolism in cancer
    105503488 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    105503488 (PRKCA)
   05214 Glioma
    105503488 (PRKCA)
   05223 Non-small cell lung cancer
    105503488 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105503488 (PRKCA)
   05161 Hepatitis B
    105503488 (PRKCA)
   05171 Coronavirus disease - COVID-19
    105503488 (PRKCA)
   05164 Influenza A
    105503488 (PRKCA)
   05163 Human cytomegalovirus infection
    105503488 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105503488 (PRKCA)
   05143 African trypanosomiasis
    105503488 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    105503488 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    105503488 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    105503488 (PRKCA)
   05032 Morphine addiction
    105503488 (PRKCA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105503488 (PRKCA)
   05415 Diabetic cardiomyopathy
    105503488 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    105503488 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105503488 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cang01001]
    105503488 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cang04131]
    105503488 (PRKCA)
Enzymes [BR:cang01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     105503488 (PRKCA)
Protein kinases [BR:cang01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   105503488 (PRKCA)
Membrane trafficking [BR:cang04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    105503488 (PRKCA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C2 C1_1 Pkinase_C ABC1
Other DBs
NCBI-GeneID: 105503488
NCBI-ProteinID: XP_011785808
LinkDB
Position
Unknown
AA seq 673 aa
MRFPHLYEAVYGPSMQQGASKLTQGTEGSANVVFAKEPGLRNGEPQNPGAAQVLPEPSIW
PLRERIFCFFCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCG
SLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRD
AKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRR
LSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNM
ELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRK
GTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEY
VNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKI
ADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFD
GEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRR
IDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYV
NPQFVHPILQSAV
NT seq 2022 nt   +upstreamnt  +downstreamnt
atgcgcttccctcatttatatgaagccgtgtatggtccctccatgcagcagggcgcgtcc
aagctgacccagggaactgagggatcagccaatgtagtgtttgccaaggagccaggcctc
aggaatggagagccccagaatccaggtgcagcacaggtgcttccagaaccttctatttgg
ccccttcgggaaaggatcttctgttttttttgctgttttgtggtccacaagaggtgccat
gaatttgttactttttcttgtccgggtgcggataagggacccgacactgatgaccccagg
agcaagcacaagttcaaaatccacacttatggaagccccaccttctgcgatcactgtggg
tccctgctatatggacttatccaccaagggatgaaatgtgacacctgcgatatgaacgtt
cacaagcagtgcgtcatcaacgtccccagcctctgcggaatggatcacacagagaagagg
gggcggatttacctaaaggctgaggttgctgatgaaaagctccatgtcacagtacgagat
gcaaaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaa
cttattcctgatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgctccacacta
aatccccagtggaatgagtcctttacattcaaattgaaaccttcagacaaagaccgacga
ctgtctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatccctt
tcctttggggtttcggagctaatgaagatgccagccagtggatggtacaagttgcttaac
caagaagaaggtgagtactacaatgtacccattccagaaggggacgaagaaggaaacatg
gaactcaggcagaaattcgagaaagccaagcttggccctgctggcaacaaagtcatcagt
ccctctgaagacaggaaacaaccttccaacaacctggaccgagtgaaactcaccgacttc
aatttcctcatggtgctggggaaggggagttttggaaaggtgatgcttgccgataggaag
ggcacagaagaactgtacgcaatcaaaatcctgaagaaggatgtggtgattcaggatgat
gacgtggagtgcaccatggtagaaaagcgagtcttggccctgcttgacaaacccccgttc
ttgacacagctgcactcctgcttccagacagtggatcggctgtacttcgtcatggaatat
gtcaacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaa
gcagtattctatgcggcagagatttccatcggattgttctttcttcataaaagaggaatc
atttatagggatctgaagttagataacgtcatgttggattcagaaggacatatcaaaatt
gctgactttgggatgtgcaaggaacacatgatggatggagtcacgaccaggaccttctgt
gggactccagattacatcgccccagagattatcgcttatcagccatatggaaaatctgtg
gactggtgggcctatggcgtcctgttgtatgaaatgcttgccgggcagcctccatttgat
ggtgaagatgaagacgagctatttcagtctatcatggagcacaacgtttcctatccaaaa
tccttgtccaaggaggctgtttccatctgcaaaggactgatgaccaaacacccagccaag
cggctgggctgtgggcctgagggggagagggacgtgagagaacatgccttcttccggagg
atcgactgggaaaaactggagaacagggagatccagccaccattcaagcccaaagtgtgc
ggcaaaggagcagaaaactttgacaagttcttcacacgagggcagcccgtcttaacaccg
cctgatcagctggttattgctaacatagaccagtctgattttgaagggttctcgtatgtc
aacccccagtttgtgcaccccatcttacagagtgcagtatga

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