Colobus angolensis palliatus (Angola colobus): 105508462
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Entry
105508462 CDS
T08744
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
cang
Colobus angolensis palliatus (Angola colobus)
Pathway
cang01521
EGFR tyrosine kinase inhibitor resistance
cang04062
Chemokine signaling pathway
cang04081
Hormone signaling
cang04148
Efferocytosis
cang04151
PI3K-Akt signaling pathway
cang04217
Necroptosis
cang04550
Signaling pathways regulating pluripotency of stem cells
cang04630
JAK-STAT signaling pathway
cang04658
Th1 and Th2 cell differentiation
cang04659
Th17 cell differentiation
cang04725
Cholinergic synapse
cang04917
Prolactin signaling pathway
cang04920
Adipocytokine signaling pathway
cang04933
AGE-RAGE signaling pathway in diabetic complications
cang04935
Growth hormone synthesis, secretion and action
cang05140
Leishmaniasis
cang05145
Toxoplasmosis
cang05152
Tuberculosis
cang05161
Hepatitis B
cang05164
Influenza A
cang05167
Kaposi sarcoma-associated herpesvirus infection
cang05168
Herpes simplex virus 1 infection
cang05200
Pathways in cancer
cang05207
Chemical carcinogenesis - receptor activation
cang05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cang05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cang00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105508462 (JAK2)
04151 PI3K-Akt signaling pathway
105508462 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
105508462 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105508462 (JAK2)
09143 Cell growth and death
04217 Necroptosis
105508462 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
105508462 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
105508462 (JAK2)
04659 Th17 cell differentiation
105508462 (JAK2)
04062 Chemokine signaling pathway
105508462 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
105508462 (JAK2)
04917 Prolactin signaling pathway
105508462 (JAK2)
04935 Growth hormone synthesis, secretion and action
105508462 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
105508462 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105508462 (JAK2)
05207 Chemical carcinogenesis - receptor activation
105508462 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105508462 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
105508462 (JAK2)
05164 Influenza A
105508462 (JAK2)
05168 Herpes simplex virus 1 infection
105508462 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
105508462 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
105508462 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105508462 (JAK2)
05140 Leishmaniasis
105508462 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105508462 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105508462 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105508462 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cang01001
]
105508462 (JAK2)
Enzymes [BR:
cang01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105508462 (JAK2)
Protein kinases [BR:
cang01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105508462 (JAK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
105508462
NCBI-ProteinID:
XP_011792718
Ensembl:
ENSCANG00000040653
UniProt:
A0A2K5JYU7
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEETSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSG
EYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYF
PRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG
MAVLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSDESRVVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSKLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWA
MHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNLRPSFRDLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcctgccttactatgacagaaatggaggaaacatccacatcttctatatat
cagaatggtgatatttctggaaatgccaattctatgaagcaaatagatccagtccttcag
gtgtatctttaccattcccttgggaaatctgaggcagattatctgacctttccatctggg
gagtatgttgcagaagaaatctgtattgctgcttctaaagcttgtggtatcacacctgtg
tatcataatatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccat
gtcttccatatagatgagtcaaccaggcataatgtactctacagaataagattttacttt
cctcgttggtattgcagcggcagcaacagagcctatcggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctctttgctcagtggcggcatgat
tttgtgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaatgatcaaaccccactggccatc
tataactctatcagctataagacattcttaccaaaatgtattcgagcaaagatccaagac
tatcatattttgacaaggaagcgaataaggtacagatttcgcagatttattcagcagttc
agccaatgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaacc
ctgcagtctgccttctacacagagaaatttgaagtaaaagaacctggaagtggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgatttt
cctaatattattgatgtcagtattaagcaagcaaaccaagagggttcagatgaaagccga
gttgtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagg
gaagctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcacctccaacagtgcttgaaaatatacaaagcaactgt
catggcccaatttcgatggattttgccattagtaaactgaagaaagcaggtaatcagact
ggactgtatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gtcgagcgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgaa
gagtacaacctcagtgggacaaagaagaacttcagcagtcttaaagatcttttgaattgt
taccagatggaaaccgttcgctcagacaatataattttccagtttactaagtgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaacgaatggtgtttctgatgta
ccaacctcaccaacattacagaggcctactcatatgaaccaaatggtgtttcacaaaatc
agaaatgaagatttgatatttaatgaaagccttggccaaggcacttttacaaagattttt
aaaggcatacgaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagcaagctttctcacaagcatttggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtaaaatttggatcactagatacatacctgaaaaag
aataaaaactgtataaatatattgtggaaacttgaagttgcgaaacagttggcatgggcc
atgcattttctagaagaaaacacccttattcatgggaatgtgtgcgccaaaaatattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatttaaatttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataaacctctaagtgctctggattctcaa
agaaaactgcaattttatgaagataggcaccagcttcctgcaccaaagtgggcagaatta
gcaaaccttataaataattgtatggattatgagccagatttcaggccttctttcagagcc
atcatacgagatcttaacagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgaggataggtgccctagggttttctggtgcctttgaagacagggat
cctacacagtttgaagagagacatttgaaatttctacagcaactcggcaagggtaatttt
gggagtgtggagatgtgccggtatgaccctctacaggacaacactggggaggtggtggct
gtaaaaaagcttcagcatagtactgaagagcacctgagagactttgaaagggaaattgaa
atcctgaaatccctacagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggtcggcgtaatctaaaattaattatggaatatttaccatatggaagtttacgagactat
cttcaaaaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaga
aatatattggtggagaatgagaacagagttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactataaagtaaaagaacctggtgaaagtcccatattctgg
tatgctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagtttt
ggagtggttctgtatgaactttttacatacattgagaagagtaaaagtccaccagcggaa
tttatgcgtatgattggcaatgataaacaaggacagatgatcgtgttccatttgatagaa
cttttgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatatg
atcatgacagaatgctggaacaataatgtaaatctgcgcccctcctttagagatttagct
cttcgagtggatcaaataagagataacatggctggatga
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integrated database retrieval system
