Colobus angolensis palliatus (Angola colobus): 105510426
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Entry
105510426 CDS
T08744
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
cang
Colobus angolensis palliatus (Angola colobus)
Pathway
cang00010
Glycolysis / Gluconeogenesis
cang00020
Citrate cycle (TCA cycle)
cang00620
Pyruvate metabolism
cang00785
Lipoic acid metabolism
cang01100
Metabolic pathways
cang01200
Carbon metabolism
cang01210
2-Oxocarboxylic acid metabolism
cang04066
HIF-1 signaling pathway
cang04922
Glucagon signaling pathway
cang05230
Central carbon metabolism in cancer
cang05415
Diabetic cardiomyopathy
Module
cang_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cang00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105510426 (PDHA1)
00020 Citrate cycle (TCA cycle)
105510426 (PDHA1)
00620 Pyruvate metabolism
105510426 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105510426 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105510426 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105510426 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105510426 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105510426 (PDHA1)
Enzymes [BR:
cang01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105510426 (PDHA1)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF1117
DUF4599
Motif
Other DBs
NCBI-GeneID:
105510426
NCBI-ProteinID:
XP_011795589
Ensembl:
ENSCANG00000022099
LinkDB
All DBs
Position
Unknown
AA seq
440 aa
AA seq
DB search
MTLSRRAATEAWRLLGHLKETLGHPRRASWAVRSRRCRQCLCFMRKMLAAVSRVLSGASQ
KSASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLS
VREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVC
LTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIP
GLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEV
RSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYS
SDPPFEVRGANQWIKFKSVS
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgactctgtcacgtcgcgctgcgactgaggcgtggcgtctgctggggcacctgaaggag
actttgggacacccgcgtcgtgcctcttgggctgtgaggagtcgccgctgccgccagtgc
ctgtgcttcatgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcag
aagtcggcaagcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaa
attaagaaatgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcacc
agggaggatgggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaa
gcagatcagttgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcag
tttctccttcctctaacacaggaagcttgctgtgtgggcctggaagccggcatcaacccc
acagaccatctcataacagcctaccgggctcacggctttaccttcacccggggcctttcc
gtccgagaaattctcgcagagcttacaggacgaaaaggaggttgtgctaaagggaaagga
ggatcgatgcacatgtatgccaagaacttctacgggggcaatggcatcgtgggagcgcag
gtgcccctgggcgctgggattgctctagcctgtaagtataatggaaaagatgaggtctgc
ctgactttatatggcgacggtgctgctaaccagggccagatattcgaagcttacaacatg
gcagctttgtggaaattaccttgtattttcatctgtgagaataatcgctatggaatggga
acatctgttgagagagcagcagccagcactgattactacaagagaggcgatttcattcct
gggctgagagtggatggaatggatatcctgtgcgtccgagaggcgacaaggtttgctgct
gcctattgtagatctgggaaggggcccatcctgatggagctgcagacttatcgttaccac
ggacacagtatgagtgatcctggagtcagttaccgtacacgagaagaaattcaggaagta
agaagtaagagtgaccctattatgcttctcaaggacaggatggtgaacagcaatcttgcc
agtgtggaagaactaaaggaaattgatgtggaagtgaggaaggagattgaggatgctgcc
cagtttgccacggccgatcctgagccacctttggaggagctgggctaccacatctactcc
agcgacccacctttcgaagttcgcggtgccaatcagtggatcaagtttaagtcagtcagt
taa
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