Colobus angolensis palliatus (Angola colobus): 105515989
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Entry
105515989 CDS
T08744
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
cang
Colobus angolensis palliatus (Angola colobus)
Pathway
cang04140
Autophagy - animal
cang04141
Protein processing in endoplasmic reticulum
cang04210
Apoptosis
cang04932
Non-alcoholic fatty liver disease
cang05010
Alzheimer disease
cang05012
Parkinson disease
cang05014
Amyotrophic lateral sclerosis
cang05016
Huntington disease
cang05017
Spinocerebellar ataxia
cang05022
Pathways of neurodegeneration - multiple diseases
cang05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cang00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
105515989 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105515989 (ERN1)
09143 Cell growth and death
04210 Apoptosis
105515989 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
105515989 (ERN1)
05012 Parkinson disease
105515989 (ERN1)
05014 Amyotrophic lateral sclerosis
105515989 (ERN1)
05016 Huntington disease
105515989 (ERN1)
05017 Spinocerebellar ataxia
105515989 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
105515989 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105515989 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
105515989 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cang01001
]
105515989 (ERN1)
Enzymes [BR:
cang01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105515989 (ERN1)
Protein kinases [BR:
cang01001
]
Serine/threonine kinases: Other
IRE family
105515989 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
CytochromB561_N
Med31
Motif
Other DBs
NCBI-GeneID:
105515989
NCBI-ProteinID:
XP_011803385
Ensembl:
ENSCANG00000032329
UniProt:
A0A2K5IMW3
LinkDB
All DBs
Position
Unknown
AA seq
979 aa
AA seq
DB search
MPARRLLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKSKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVS
RDVEEKPAHAPARPEAPVDSVLKDVATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQF
QKELEKIQLLQQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPNTSPRASNHSLC
SGSSASKAGSSPSLEQDDGDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAV
KRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF
AHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKL
AAGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKS
LQRQANILLGACSLECLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQ
LQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVR
DLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQ
PYYFHRPPEPQPPVTPDAL
NT seq
2940 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctgctgctgctgctgctgacgctgctgctgcccggcctcgggatt
tttggaagcaccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaacgctggat
ggaagtttgcatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagat
ccagtcctgcaggtcccaacgcatgtggaagagcctgcctttctcccagatcctaatgat
ggcagcctgtatacgcttggaagcaagaataatgaaggcctgacgaaacttccttttacc
atcccagaattggtgcaggcatccccatgccgaagttcagatggaatcctctacatgggt
aaaaagcaggacatctggtatgttattgacctcctgactggggagaagcagcagaccttg
tcatcagcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcgaaca
gaatacaccatcaccatgtacgacaccaaaacccgagagctccggtggaatgccacctac
tttgactatgcagcctcgctgcctgaggacgacatggactacaagatgtcccactttgtg
tccaatggtgatgggctggtggtgaccgtggacagtgaatctggggatgtcctgtggatc
caaaactacgcctcccctgtggtggccttttatgtctggcagcgggagggtctcaggaag
gtgatgcacatcaatgtcgctgtggagaccctgcgctatctgaccttcatgtctggggag
gtggggcgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagcaag
ctgacgcccactctgtatgttgggaaatactctaccagcctctatgcctctccctcaatg
gtacacgagggagttgctgtcgtgcctcgcggcagcacacttcctttgctggaagggccc
cagactgatggcgtcaccattggggacaagggggagtgtgtgatcacgcccagcacagac
ctcaagtttgaccccggactcaaaagcaagaacaagctcaactacttgaggaattactgg
cttctgataggccaccatgaaaccccactgtctgcgtctaccaagatgctggagagattc
cccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcagagaaaaagagc
tttgaggaagttatcaacctggttgaccagacttcagaaaacgcacctaccaccgtgtct
cgggatgtggaggagaagcccgcccatgcccctgcccggcccgaggcccccgtggactcc
gtgctcaaggacgtggccaccatcatcctgagcaccttcctgctgattggctgggtggcc
ttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccagcagttt
cagaaggaactggagaagattcagctcctgcagcagcagcagcagcagcagctgcccttc
cacccacctggagacacggctcaggacggcgagcttctggacacgtctggcccatactca
gagagctcgggcaccagcagccccaacacgtcccccagggcctccaaccactcgctctgc
tctggcagctctgcctccaaggctggcagcagcccctccctggaacaagatgacggagat
gaggaaaccagcatggtgatagttgggaaaatttccttctgtcccaaggacgtcctgggc
cacggagctgagggcacaattgtgtaccggggcatgtttgacaaccgtgatgtggccgtg
aagaggatcctccccgagtgttttagcttcgcagaccgtgaggtccagctgttgcgagaa
tcagatgagcacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccag
tacattgccatcgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggacttt
gcgcatctcggcctggagcccatcaccttgttgcagcagaccacctcgggcctggcccac
cttcactccctcaacatcgttcacagagacctaaagccccacaacattctcatatccatg
cccaatgcacatggcaagatcaaggccatgatctctgactttggcctgtgcaagaagctg
gcagcgggcaggcacagcttcagccgccgatctggggtgcctggcacagaaggctggata
gctccagagatgctgagcgaagactgtaaggagaaccctacctacacagtggacatcttt
tctgcaggctgcgtcttttactacgtgatctctgagggcagccacccttttggcaagtcc
ctgcagcggcaggccaacatcctcctgggtgcctgcagcctcgagtgcttgcacccagag
aagcacgaagacgtcattgcacgtgaattgatagagaagatgattgcgatggatcctcag
aaacgcccctcagcgaagcacgtgctgaaacacccattcttctggagcctagagaagcag
ctccagttcttccaggacgtgagtgacagaatagaaaaggaatccctggatggcccgatt
gtgaaacagttagagagaggcgggagagccgtggtgaagatggactggcgggagaacatc
accgtccccctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcaga
gatctcctccgagccatgagaaataagaagcaccactaccgggaactgcctgcagaggtg
cgggagacgctgggttccctccctgacgacttcgtgtgctacttcacgtctcgcttcccc
cacctcctcgcacacacctaccgggccatggagctgtgcagccacgagagactcttccag
ccctactacttccacaggcccccagagccccagcccccagtgactccagacgccctctga
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