KEGG   Colobus angolensis palliatus (Angola colobus): 105517524
Entry
105517524         CDS       T08744                                 
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
  KO
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
Organism
cang  Colobus angolensis palliatus (Angola colobus)
Pathway
cang00230  Purine metabolism
cang00670  One carbon pool by folate
cang01100  Metabolic pathways
cang01523  Antifolate resistance
Module
cang_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:cang00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    105517524 (GART)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    105517524 (GART)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    105517524 (GART)
Enzymes [BR:cang01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.2  phosphoribosylglycinamide formyltransferase 1
     105517524 (GART)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.3  Cyclo-ligases
    6.3.3.1  phosphoribosylformylglycinamidine cyclo-ligase
     105517524 (GART)
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.13  phosphoribosylamine---glycine ligase
     105517524 (GART)
SSDB
Motif
Pfam: GARS_A Formyl_trans_N AIRS_C GARS_C AIRS GARS_N ATP-grasp CPSase_L_D2 ATP-grasp_2 ATP-grasp_4 ATP-grasp_3 Dala_Dala_lig_C RimK LUD_dom DiatomPyrShell
Other DBs
NCBI-GeneID: 105517524
NCBI-ProteinID: XP_011805449
Ensembl: ENSCANG00000003930
LinkDB
Position
Unknown
AA seq 994 aa
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTVPGETLVHLRLL
FSSVGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHRIPTAQWKAFTKPEEACSF
IMSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGE
EVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQ
RTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQST
LDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFSEAQALGLEVFHAGTALKN
GKVVTHGGRVLAVTAIRENLNSALEEAKKGLAAIKFEGAIYRKDIGFRAIAFLQEPRGLT
YKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGV
GTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIA
KACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIAS
SGLHSNGFSLVRKIVTKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVK
AFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPKVFSWLQQEGHLSEEEMARTFNCGVG
AALVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSLLKNGS
LKNHFSFGKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDVVISNKAAVAGLDKAERA
GIPTRVINHKLYKNRVEFDNAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHP
SLLPSFKGSNAHEQALETGVTITGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERV
KLAEHKTFPAALQLVASGTVQLGENGKICWVKEE
NT seq 2985 nt   +upstreamnt  +downstreamnt
atggcagcccgagtacttataattggcagtggaggaagggaacatacgctggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaataccgttcctggggagaccttggttcacctaaggctactg
ttttcatccgtagggattgttgggaacctgacgtctgcaggagtgcgatgctttggccca
acagcagaagcggctcagttagagtccagcaaaaggtttgccaaagagtttatggacaga
catagaatcccaactgctcaatggaaggctttcaccaaacctgaggaggcctgcagcttc
attatgagtgcagacttccctgctttggttgtgaaggccagtggtcttgcggctggaaaa
ggggtgattgttgcaaagagcaaagaagaggcctgcaaagctgtacaagagatcatgcag
gagaaagcctttggggcagctggagaaacaattgtcattgaagaacttcttgatggagaa
gaggtgtcttgtctgtgcttcactgatggcaagactgtggcccccatgcccccggcacag
gaccataagcgattactggagggagatggcggccctaacacagggggaatgggagcctat
tgtccagcccctcaggtttctaatgatctattactaaaaattaaagatactgttcttcag
aggacagtggatggcatgcagcaagagggtactccatatacaggtattctctatgctgga
ataatgctgaccaaggatggcccaaaagttctagagtttaattgccgttttggtgatcca
gagtgccaagtaatcctcccacttcttaaaagtgatctttatgaagtgattcagtccacc
ttagatggactgctctgcacatctctgcctgtttggctagaaaaccacaccgccctaact
gttgtcatggcaagtaaaggttatcctggagactacaccaagggtgtagagataacaggg
ttttctgaggctcaagctctaggactggaggtgttccacgcaggcactgcccttaaaaat
ggcaaagtagtaactcatgggggtagagttcttgcagtcacagccatccgggaaaatctc
aattcagctctcgaggaagccaagaaaggactagcggctataaagtttgagggagcaatt
tataggaaagacatcggctttcgtgccatagctttcctccaggagcccaggggtttgact
tacaaggaatctggagtagacattgcagctggaaatatgctggtcaagaaaattcagcct
ttagcaaaagccacttccagatcaggctgtaaagttgatcttggaggttttgctggtctt
tttgatttaaaagcagctggtttcaaagatccccttctggcctctggaacagatggcgtt
ggaactaaactaaagattgcccagctgtgcaacaaacatgataccattggtcaagatttg
gtagcaatgtgtgttaatgatattctggcacaaggagcagagcccctcttcttccttgat
tacttttcctgtggaaaacttgacctcagtgtaactgaagccgttgttgctggaattgct
aaagcttgtggaaaagctggatgtgctcttcttggaggtgaaacagcagaaatgcctgac
atgtatccccctggagagtatgacctagctgggtttgccgttggtgccatggagcgagat
cagaaactccctcacctggaaagaatcaccgagggtgatgttgttgttggaatagcttca
tctggtcttcatagcaatggatttagccttgtgaggaagatcgtgacaaaatcttccctc
cagtactcctctccagcacctgatggttgtggtgaccagactttaggggacttacttctc
acgccaaccagaatctacagccattcactgttacctgtcctacgttcaggacatgtcaaa
gcctttgcccatattactggtggaggattactagagaacatccccagagtcctccctgag
aaacttggggtagatttagatgcccagacctggaggatccccaaggtcttctcatggtta
cagcaggaaggacacctttctgaggaagagatggccagaacatttaactgtggggttggc
gctgcccttgtggtatcaaaggagcagacagagcagattctgagggatatccagcagcac
aaggaagaagcctgggtgattggcagtgtggttgcacgagctgaaggctccccacgtgtg
aaagtcaagaatctgattgaaagcatgcaaataaatgggtcattgttgaagaatggctcc
ctgaaaaatcatttctcttttggaaaaaaaaaggccagagtggctgtcttaatatctgga
acaggatcgaacctgcaagcactcatagacagtactcgggaaccaaatagctctgcacaa
attgatgttgtcatctccaacaaagccgcggtagctgggttagataaagcggaaagagct
ggtattcctactagagtaattaatcataaactgtataaaaatcgtgtagaatttgacaat
gcaattgacctagtccttgaagagttctccatagacatagtctgtcttgcaggattcatg
agaattctttctggcccctttgtccaaaagtggaatggaaaaatgctcaatatccaccca
tccttgctcccttcttttaagggttcgaatgcccatgagcaagccctggaaaccggagtc
acaattactgggtgcactgtacactttgtagctgaagatgtagatgctggacaaattatt
ttgcaagaagctgttcctgtgaagaggggtgatactgttgcaactctttctgaaagagta
aaattagcagaacataaaacatttcctgcagccctccagttggtggctagtggaactgta
cagcttggagaaaatggcaagatctgttgggttaaagaggaatga

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