Castellaniella sp. MT123: ABCV34_12420
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Entry
ABCV34_12420 CDS
T11683
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cast Castellaniella sp. MT123
Pathway
cast00290
Valine, leucine and isoleucine biosynthesis
cast00620
Pyruvate metabolism
cast01100
Metabolic pathways
cast01110
Biosynthesis of secondary metabolites
cast01210
2-Oxocarboxylic acid metabolism
cast01230
Biosynthesis of amino acids
Module
cast_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cast00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ABCV34_12420 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ABCV34_12420 (leuA)
Enzymes [BR:
cast01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ABCV34_12420 (leuA)
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Paralog
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
XAP00630
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Position
complement(2628336..2630039)
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AA seq
567 aa
AA seq
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MIQNPASKYVPFAPFAREFSERTWPSRRITTPPIWMSTDLRDGNQALIEPMSVERKLRFF
EQLVKIGFKEIEVGFPSASQTDYDFVRKLVEEKRIPDDVTIIGLTQARGDLIPRTVQALA
GAKHAIVHMYNACAPAFRKIVFNMSRDEVRTIAIEGTKIVKAEVAKHPETHWRYEYSPEV
FSTTEPDFALEVCNAVVETWQPTVQDKIILNMPATIEATTPNLYADQIEWMHRNLAQRDK
IVISVHPHNDRGTAVAAAELAVMAGADRIEGCLFGNGERTGNVDLVTLALNLYTQGIHPG
LDFSDIDEVRRCVEDCNQLPVHPRHPYAGDLVFTAFSGSHQDAIKKGFAIQQPDAIWEVP
YLPIDPADLGRSYDAVIRVNSQSGKGGVSYLLEQEHGLVLPRRLQIEFSRAIQRVTDETG
REVTSKDVFEVFSSEYLDLETPWKLVRHRITGSPRNTSQKQFTIEVEIQADGQTRHLSGQ
GDGAISAFVDALGIDARVMDYQEHAIGTGTDTRAASYVEMRIGDAPNGYGVGIHEDIVTS
SFLAILSAVNRQAAAGKEIPARASVAA
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgatccagaaccccgcctccaaatacgttccgttcgcgccatttgcgcgtgaattttcc
gaacgcacctggcccagccgccgcatcaccacgccgccgatctggatgagcaccgatctg
cgcgatggcaaccaggcgctgatcgagcccatgagcgtagagcgcaaactgcgcttcttc
gaacagctggtgaagatcggcttcaaggaaatcgaggtcggctttccgtccgcctcgcag
acagactacgacttcgtgcgcaaactggtcgaggaaaagcgcattcccgatgacgtcacc
atcatcggcctgacccaggcacgcggcgacctgatcccccgcacggtacaggccctggcc
ggcgccaaacacgccatcgtgcacatgtacaacgcctgcgcaccggctttccgcaagatc
gtgttcaacatgagccgcgacgaggtccgcacgatcgccatcgagggcacgaagatcgtc
aaggccgaagtcgccaaacacccggaaacccactggcgctacgaatactcgcccgaagtc
ttcagcacgacggagccggatttcgcgctggaagtctgcaatgccgtggtcgagacctgg
cagccgaccgtgcaggacaagatcatcctgaacatgccggccaccatcgaggccaccacc
ccgaacctgtacgccgaccagatcgaatggatgcaccgcaatctggcacagcgcgacaag
atcgtcatcagcgtccacccgcacaatgaccgcggcaccgcggtggctgcggccgaactc
gccgtcatggccggggccgaccgcatcgaaggctgtctgttcggcaacggcgaacgcacc
ggcaacgtagacctggtcaccctggccttgaacctgtacacgcagggcatccatccgggc
ctggatttttcggacatcgacgaggtccgccgctgcgtcgaggactgcaatcagttgccc
gtgcatccgcgccatccgtatgcgggcgatctggtgttcaccgcgttttcgggttcgcac
caagacgccatcaaaaagggcttcgccatacagcagcccgacgccatctgggaagttccc
tacctgccgatcgatccggccgatctgggccgcagctacgacgccgtcatccgcgtcaac
agccagtccggcaagggcggcgtgtcctatctgctggaacaggaacacggcctggtcctg
ccgcgccgcctgcagatcgagttcagccgcgccattcagcgcgtcaccgacgaaaccggc
cgcgaagtcacatccaaggacgtgttcgaggtcttctccagcgaatacctggatcttgaa
accccgtggaagctggtccggcatcgcatcacaggcagccccaggaacacaagccagaaa
cagttcacgatcgaggtcgaaattcaggccgatggccagacgcgccacctgtccggccag
ggcgacggcgccatctcggccttcgtcgatgcgctgggcatcgatgcgcgcgtcatggac
tatcaggaacacgccatcggcacgggcaccgacacccgggcggcatcctatgtggaaatg
cgcatcggcgacgcacccaacgggtacggcgtgggcatccacgaagacatcgtgacgtcg
tcgttcctggcgattctgagcgccgtcaaccggcaggccgccgccgggaaggaaatcccg
gcccgcgcatcggtcgcggcctga
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