Cygnus atratus (black swan): 118244246 Help Entry 118244246         CDS       T09349                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism cata  Cygnus atratus (black swan) Pathway cata04020   Calcium signaling pathway cata04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:cata00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     118244246 (RYR3)    04020 Calcium signaling pathway     118244246 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cata04040]     118244246 (RYR3) Ion channels [BR:cata04040]  Voltage-gated cation channels   Ryanodine receptor    118244246 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD Motif Other DBs NCBI-GeneID:  118244246 NCBI-ProteinID:  XP_050566795 LinkDB All DBs Position 5:26168632..26358875 Genome browser AA seq 4861 aa AA seqDB search MAVDDEVVLQCVASVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCICNFVLEQSL SVRALQEMLANTGDNASEGAAQGGHRTLLYGHAILLRHSFSEMYLTCLTSSRSQTDKLAF DVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSMSNGSIQVDA SFMQTLWNVHPTCSGSNITEGYLLGGHVVRFFHGHDECLTIPSTDQNDSQQKKVLYETGG AGVRARSLWRVEPLRISWSGSNIKWGQPFRLRHITTGMYLALNDDEGLVMLDREKSDTTS TAFCFRASKELKEKQDSTLKRDIDGMGVPEIKYGDSVCFVQHVASALWLTYKAQDAKSAR LGLLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQFLSGNNRTLSPIALP VEEMAQTLQDLITYFQPPEEDLEHEDKQSKLRSLKNRQNLFKEEGMLALVLNCIDRLNDS NSAAHFAEIAREENGTTWKEILNLLYKLLAALIRGNRNNCTQFSSNLDWLISKLDRLESS SGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYKVLDVLCSLCVCNGVAVRAN QNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTA EPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRVPRAVASVNQHL LSSDDVVSCCLDLGVPSISFRINGQPVQGMFENFCTEGFFFPVVSLSAGVKARFLLGGRH GEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGTTQFLSQASFIPCPID TSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKRHHPCLVEFSKLPETE KNYNLQMSTETLKTLLALGCHIVHANPAAEEDLKKVKLPKNYMMSNGYKPAPLDLSEVKL LPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYALLDERTKKSNRD SLREAVRTFAGYGYSVEPPDQEIADQATEKVSIDKIRFFRVEQSYAVKSGKWYFEFEAVT GGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGRSWQPGDVVGCMINLD DKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGRMNLGMDASTFKYYTM CGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEIWRIDGTIESPPRLKVTHKT FGTQNSSSDMIYCRLSMPIEFRSSFNFGMGVENASSDVFQKRKHSQEVSVPSTTYFYSLR IFAGQDPSCVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGG DITSNSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTCYQVEPNTKLFPATFVQPTS TNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPVLWSRMPNSFLKVETE RVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFHYHTLKLYSSVCALGN TRVAYALCSHVDVSQLFYTIDNQYLPGLLRSGFYDLLISIHLEHAKQAKLMMNNEFIIPV TEETRTIRLYPDETKKHGLPGVGLSTCLKPSFHFSAPCFIVTSEEHQTSSPEIPLDTLKS KAISMLTEAVQCSGAHIRDPVGGHIAFQFVPVLKLIATLLIMGVFDDDDVKQVLILIDPN VFGDHKEETEEGTEKEEVTQVEEKAVEAGEKAIKETKAPTTGLLQTRLPESVKLQMCHLL NYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQALNMSAALTAKKTKEFRSPPQ EQINMLLNFQLGEDCPCPEEIRDELYDFHDDLLIHCGIPLEEEEEEEEDSTLTGKLRSLI YKIKGPPKAEKVEPREEEEKSPTTLKELISQTMVRWSQEDQIQDPELVRIMYTLLRRQYD SIGELLQALRKAYTISATSVKDTINLLAALGQIRSLLSVRMGKEEELLMINGLGDIMNNK VFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQQIVFPKMVASCCRFLCYFCRISRQNQKA MFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALEEPDLDKVVTYLAGCG LQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGP DLRGEGGNGLLAAMQEAIRISENPSRDLPSQGYRREGDEEEEEEEIVHMGNAIMSFYSAL IDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPLKLSTVNKDGTVNEPD MSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASASLDTVSLSTTEAALA LNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRSLTKAQRDTIEECLLA ICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKYYCLPSGMGSYGIAAE EELHLTEKLFWGIFDSLSHKFLSLLQKYDPELFRMALPCLSAIAGALPPDYLDTRIRSTL EKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAFDKTNNGWKYGVSLDE NTKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKEGGEAILHQRENEKLR SISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKKKKMELESKGGGSHPL LVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMDLDASSMEKRFAFKFLKKIL KYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHCLYFLSSPTKT LSSSGYASNKEKEMVASLFCKLAALVRHRISIFGSDSTTMVSCLHILAQSLDTRTVMKSG SELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPVLTSIF EHISQYQFGVDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVA FLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGLIKEINDLAESGARYT EMPHVIEVILPMLCNYLSYWWERGSESVPESAGPFCTMITSEHLSIILGNILKIINNNLG IDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIVMEEEQLKADSKTDTQ EAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDELFRMVAEVFILWCKS HNFKREEQNFVIQNEINNLAFLTGDTKSKMSKAMQVKSGGQDQERKKSKRRGDLYSIQTS LIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDEEVREHLRNNLHLQEKSDDPAV KWQLNLYKDILKSDEPTDPEKNVERVQRISAALYHLEQVEQPLRSKKAVWHKLLSKQRKR AVVACFRMAPLYNLPRHRSINLFLHGYQNYWIETEEYSFEEKLVQDLAKPPKKDEEEEED TEKKQPDPLHQIILYFSRNALTERSKLEDDPLYIAYSAMMAKSCQEEEEEEEEEKEKTFE EKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHTGPMVVETLKLGIAILNGGNTIVQQ KMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKV LQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQESISDFY WYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLH VFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSSN VELILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQKQYIQSEIEFLLSC AEADENDMFNYVDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQSLLEPAESVLNYF EPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESKRQFIFDVVNEGGEQEKMELF VNFCEDTIFEMQLASQISETDSAERPEEEEEESCYVVDIGDDEEEEKSLESPSAFAMACA AVKKNVTNFFKMVTVKNLRKQYRKVRKMTVKEMVKVFFSFFWILFVGMFQLFFTIVWGIF QILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDVTEAEKAEGAEHGIRAELVQF VKGEKAETDIISDIFGIPTKKEGGSKHGHDAGLGDIAEMLGSDIQSSLENTVRKKKGLQL SEIAKEAEAERKVEAEKADMEDGEKQDKAKEVLSEQLEEGKVKKKKRRHGQKIEKPEAVM ANFFKALEIYQTKMLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLDEVEEDSNLW NTFDEEEEEEGMVFFVLEESTGYMAPALRALAVIHTIISFVCVIGYYCLKVPLVVFKREK EVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAE RIAELLGLDKNALDFSPVEESEPEEASLLSWLSSIDTKYHIWKLGVVFTDNSFLYLAWYT TMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAF NFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVF DITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFE THTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPAGDCFRKQYEDQL G NT seq 14586 nt NT seq  +upstreamnt  +downstreamnt atggcagtggatgacgaagtagtacttcagtgtgttgccagcgttcacaaagaacaaagg aagttttgcttggcagctgagggacttgggaatcgcctgtgctttttggaaccaacatca gaagctaaatatgttcctccggacctttgcatctgtaattttgtacttgaacagtccctg tctgtcagagcccttcaagaaatgctggccaacacaggggataatgccagtgaaggggct gctcaaggtggtcacagaaccctgctatatggtcatgctatactacttcgacattcgttc agtgaaatgtatttgacttgtttaacatcatcaagatcccagacagataaacttgcattt gatgtgggactgagagaaaatgcagcaggtgaagcatgctggtggacaatacaccctgca tctaaacaaaggtcagaaggagaaaaagttcgaataggtgatgatcttatcctggtcagt gtgtcctctgaaagatacctgcatctctccatgtcaaatggaagtattcaggtggatgcc tcctttatgcagacgctttggaatgtacatcctacatgctcaggaagcaatattacagaa gggtatcttcttggtgggcatgtagtacgttttttccatggccatgatgagtgtttgaca attccatctacagatcagaatgattcacagcagaagaaagtactttatgaaactggagga gctggagttcgagcaaggtctttgtggagagtagaaccacttcgaataagttggagtgga agtaacatcaaatggggacaacctttccgtcttcgacatattacaacaggaatgtacttg gctctgaatgatgacgaaggacttgtaatgttagacagagaaaagtcagatacaacatct actgccttctgttttagagcatcaaaggagctaaaagaaaaacaggattccactcttaaa cgtgatattgatggaatgggagtcccagaaataaagtacggtgattcagtctgttttgtt caacatgtggccagtgctttatggttgacttataaagcacaggatgctaaatcagcacgt ttaggtctcttgaaaagaaaggttatattgcaccaagaaggccatatggatgatggtcta accttacaaagatgtcagcatgaagaatcccaggctgctcgaatcattcgcaatactaca agcttattcagccagtttttaagtggaaacaacagaacactatcacccatcgccctgcct gttgaggagatggctcagactctgcaagacctgattacttacttccagcctcccgaagaa gacctggaacacgaggataaacaaagcaagcttcggtcactgaaaaacagacaaaatcta ttcaaagaagagggcatgctggcactagttttgaattgcattgatcgtttaaatgactcc aacagtgcagctcattttgcagaaattgcaagagaagaaaatggtaccacatggaaagaa attttaaatctcctttacaaattgttagctgccctcattcgtggcaacagaaacaattgt actcaattttccagtaatcttgattggctaataagtaaattagacagattagaatcttcc tcaggtattttggaagtgttgcactgtatcttgattgaaagcccagaagcgttaaatata atagctgaggagcatataaaatctattatttcattgttggataaacatgggcgcaattac aaggttctcgatgtgctttgctccctctgtgtctgtaatggagttgcggttcgtgccaat caaaatttgatctgtgacaatctattgcctagaagagacttactcttgcaaacacgtttg attaatgatgtgacaagcataaggccgaacatatttttgggtgttgctgagggctctgca caatacaagaagtggtactttgaattaataattgatcaggttgatccattcttgacggca gaacccacacatttacgagttggatgggcctctacttcaggttatgctccctatcctgga ggaggagaaggatggggtggcaatggtgttggcgatgacctatactcttatggttttgat ggccttcatctgtggtctggtcgagtacccagggctgtagcatctgtcaatcagcatttg ttgtcatctgatgatgtggttagctgctgcttggatttaggtgtgcccagcatttcattc cgcattaatgggcagcctgtacaaggaatgtttgagaacttctgtactgaagggtttttc ttccctgttgtaagcttatcagcaggtgtaaaagctcgtttcttattgggtggacgtcat ggagagtttaaatttctacctcctgctggctatgctccctgctatgaagccttgcttcca aaagagaagatgaaactggaaccagtgaaagaatacaagagagattctgatggagtgagg gatttgctgggtacaacacaattcctctcccaagcttcctttatcccttgtcctatagac accagtcagattgctcttccttttcatcttgaaaagatcagggacaaactagctgaaaat atccatgaactgtggggaatgaataaaatagaactgggctggacatatggcaagatacgg gatgataataaaaggcatcatccttgtcttgtagaattctcaaaattacctgagacagag aagaattataatctgcaaatgtcaactgaaactctcaaaacccttttggcccttgggtgt cacattgttcatgctaatccagcagcagaggaagatcttaaaaaagtcaagcttcctaaa aattacatgatgtcaaatggatataaacctgcccctcttgatctttctgaagtgaaattg ttaccttctcaagaattcctagttgacaaactagcagaaaatgcacataacgtctgggca aaagacagaataaagcaaggatggacctatggcattcaacaggatcttaagaacaaacgt aatcctcggctagtgccatatgcattattagatgaacgtactaaaaaatcgaacagagat agcctccgtgaagctgttagaacatttgcaggctatggttatagtgttgagccacctgac caagaaatagctgatcaagcaacggaaaaagtcagcattgacaagatacgttttttcaga gtcgaacagtcttatgcagtgaagtctggaaagtggtactttgaatttgaagctgtgaca ggtggagacatgcgtgttggctgggccaggccaggctgtcgacctgacatagaactggga gctgatgaccaagcatttgtttttgaaggaagcaaaggccagcgttggcatcaaggcagt ggattctttggacgaagttggcaaccaggagatgtggttggttgcatgataaacttggat gacaaatcaattatctttactttgaatggagaattgcttataaccagtaaaggttcagaa cttgcgtttgctgactttggaatagaaagtggttttgttccaatttgcgcactgggtctg tctcagattggacgtatgaaccttggaatggatgccagtacattcaagtattatacaatg tgtggccttcaagaaggttttgaaccttttgcagtaaatatgaaccgagatgtcgctatg tggtttagtaaacgcttaccaacatttgtcaatgtgccaaaaaatcatcctcacatagag atatggagaattgatggaaccattgaaagtccacctcggttaaaagttactcacaaaaca tttggcacacagaacagcagttcagacatgatatattgccgtttgagtatgcctattgag ttccgttcatcattcaactttggcatgggtgtggaaaatgcctcatctgatgttttccaa aaacgaaaacacagccaagaagtttctgttccttctactacgtatttttattcgttgcgg atatttgctgggcaagacccatcctgtgtctgggttggctgggtaacaccagactatcat ttttacagtgaaaattttgacctaaataaaaattgtacagtgacggttactttaggtgat gagagaggcagggttcatgaaagtgtgaagcgcagtaattgctatatggtttggggagga gatataacttctaattcccagagatcaggtcgtagcaatgttgatttagaaattggatgc tttgttgacctagctactggaatgttgtcattcacagccaatggaaaagagcttggcact tgttatcaggttgaaccaaacacaaaactttttccagcaacttttgtacagcctacgagc actaacttggttcagtttgaacttggtaaattaaagaataccatgcctttatcagcagca atttttaaaagtgaggaaagaaatcctgttcctcagtgtccccctcgccttgatgtgcaa acaattacacctgttttatggagcaggatgcctaacagctttcttaaagtagaaactgag cgtgtcagtgaacgtcatggatgggttgtgcagtgtttggaacctctgcagatgatggca ctacatatcccagaggaaaacagatgcgttgatattttggaactatgtgaacaagaagat ttgatgaagtttcactaccacactttaaaactctatagctcggtttgtgctctaggtaac actagagttgcttatgcactttgtagccatgtggatgtatctcagttattttacacaata gataatcaatatttacctggactactacgttctggattctatgacttgttgattagtata catttggagcatgccaaacaagccaagctcatgatgaacaatgaatttatcattccagtt acagaggaaactcgaactattagattatatcccgatgaaacaaagaagcatggtttacct ggagtagggcttagcacttgtctgaaaccaagctttcatttttctgctccttgctttatt gtgaccagtgaagaacatcagacatccagcccagagataccccttgatacacttaaatcc aaagccataagtatgctaacagaggcagtacagtgtagtggtgctcatatacgagaccct gttggaggacacattgcattccagtttgttcctgttcttaaactaatagcaacactgctc ataatgggggtttttgatgatgatgatgtgaagcaggtgttaatcctcattgatccaaat gtatttggagatcacaaggaagaaacagaagaggggacagaaaaggaagaagttacacaa gttgaagaaaaagctgtagaagctggagaaaaagcaataaaagaaaccaaagctcctaca acaggcttgttgcagacaagattaccagaatctgttaagcttcagatgtgccatttactc aattatttctgtgactgtgagctgcaacatagagtggaagcaattgtatcatttgcagac cgttatgtatcaaaattacagtataatcagaaatacaggtataatgaactcatgcaagcc ttgaacatgtctgcagctttgactgccaagaagactaaagaatttcggtctcctccacaa gaacagattaatatgctgctgaattttcaactgggagaggattgtccatgtccagaggag attcgggatgagctgtatgacttccatgatgatcttctaattcactgtggtattccacta gaagaggaagaagaggaagaggaagattccaccttgactggcaaactccgttcattaata tacaaaatcaaaggtccaccaaaagcagaaaaagtagagcctagggaagaagaagagaaa tcacctactacactgaaggaactcatatcccagactatggtacgctggtctcaggaagat cagattcaagatccagaattagttcggattatgtataccctccttcgtaggcaatatgac agcattggtgagctacttcaagctctgaggaaagcatacactattagtgctacctctgtg aaggatacaattaatctgcttgctgcactgggccagattcgctcacttctcagtgtcaga atgggaaaagaggaggaattgctaatgattaatggattaggggatataatgaacaacaag gtgttttatcagcatcctaacttaatgagagtcttgggcatgcatgagacagttatggat gtgatggtgaatgtgcttggaggagataagtctcagcagatcgtttttcctaagatggtg gcaagctgttgtcgattcctatgctacttctgtcgaattagtcgtcaaaaccaaaaagcc atgtttgagcatcttagttacttactggaaaacagcagcgttgggctggcatttccttca atgagaggttcaacaccactagatgttgcagcagcctccgtaatggacaacaatgagctt gcactagcactggaagagccagatctggataaagttgttacttatttggctggttgcggc ctgcagagttgtccagtattgctagctaaaggatatccagacattggatggaatccaata gagggtgaacgttacctgtcattcttaagatttgcagtttttgttaacagtgaaagtgtt gaagaaaatgcaagtgttgttgtcaagctccttattcgacggccagagtgctttggacca gaccttagaggagaaggaggaaatggtttgctggcagctatgcaagaagctatcagaatc tcagagaatccttctcgtgaccttccctcacaaggatataggagagaaggtgatgaggag gaggaagaggaggagattgtgcacatgggcaatgcaatcatgtcattttactcggctctc atagatttacttggacgctgtgcaccagaaatgcatcttattcaaagtggaaaaggtgaa gctattcgaatcaggtcaatcctccgatctctagtgccaactgaagatttggttggaatt ataagtataccactaaagctgtcaacagttaacaaagatggcacagtaaacgagccagac atgtctgcaaatttctgtcctgatcataaagcaccaatggtactcttcttggaccgtgta tatggtattaaggaccaaagcttcctccttcacctattggaagttggatttttaccagat ttaagagcttctgcctctctggatacagtttctctaagtaccacagaggcagctctcgca ctaaatagatatatttgttcagctgtgtttccattactcaaaagatgtgctcccctcttt tctggaacagagcatcatgcttctctggttgactccatgcttcacacaatatataggtta tccaaaggacgttcccttacaaaagcacaacgagacactattgaagaatgcctgcttgca atttgccaccacttacgtccctctatgctacaacagctgttgagaaggctagtttttgat gtaccgctactcaatgagtactgtaaaatgcctctcaagcttctgacaaatcactatgaa cagtgctggaaatactattgtctaccttcaggaatgggaagctatggaattgcagcagaa gaagaattacatttaactgagaaacttttctggggaatatttgattccttgtctcataag ttcctatctctcctgcagaagtatgatccagagctctttcgaatggccttgccttgtcta agtgctatagctggtgccttgcctcctgattatttagatacacgaattagatcaactttg gaaaagcagacttcagtggatccagaaggaaattttgatcccaaacctgtcagtacagca aaccttgtacttcctgaaaagttggagtatattgtcagcaagtatgctgaacattcccac gataagtgggcctttgataagactaataatggatggaaatacggtgtttcactggatgaa aatacaaagactcacccattaataagacctttcaaaactttaactgaaaaggaaaaagaa atttatcgttggcctgctagagaatcactgaaaaccatgttggccatgggatggagccta gaaaggaccaaagaaggaggagaagcaatattacatcagcgtgaaaatgaaaagctccgt agcatatctcagtctagccagggaaatggatatagcccagcaccacttgatctctctaat gtggtgctttctagggagcttcagggaatggttgaggtaatggcagaaaactaccataat atatgggccaaaaagaagaaaatggagttggaaagcaaaggtggaggtagtcatccttta ttggtaccttatgacacattgacagccaaggagaaatcacgggaccgtgaaaaggcacag gagctgtttaaattccttcaagtgaatggtataatcatatctcggggtctgaatgacatg gatttggatgcttcatccatggaaaagaggtttgcctttaagtttctgaagaaaatttta aaatatgttgactctgctcaagagtttattgcacatttggaagccattgtaaccagtgga aaaactgaaaaatctccacatgaccaagaaataaaattctttgcgaaagttcttttaccg ttagttgatcagtactttacaaatcactgcctgtacttcctgtcttctccaacaaaaaca ctcagtagcagtggatatgcatcaaataaggaaaaggaaatggtagcaagcctgttctgc aaactagctgctcttgttagacataggatctcaatttttggtagtgattctacaacaatg gttagctgcctgcacatcttagctcagtctcttgacactcgaactgttatgaaatcggga tctgagctagttaaagctggattacgtgccttttttgaaaatgcagctgaagatctggaa aaaacttcagaaaatcttaaacttggaaaatttacccattcacgaacacaaatcaagggt gtttcacagaatatcaattatactacagtagcattgttacctgtcttgacatcaattttt gagcatatttcacagtatcagtttggagttgatttacttttgggtgatgtacaagtttca tgttatagaattctttgtagcctctattcccttgggactgggaagaacatctatgttgaa aggcagcgccctgcacttggtgagtgcttagcatctcttgcggcagccattccggtagca tttcttgaaccttctctcaaccattacaacccattgtctgtcttcaacacaaaaagtgca agagaaagagcaattttaggtatgcctgatacagtagaggagatgtgtccagagattccc cagttggatggactaataaaggaaattaatgatttagcagagtctggagcaaggtatact gaaatgcctcatgtaattgaggttatcttacccatgctatgcaactatttgtcctactgg tgggaacgagggtccgagagtgttcctgaaagtgccgggcctttctgtacaatgataacg tctgaacatctaagcatcattctgggaaacattctgaaaatcattaacaacaatctggga atagatgaagcatcttggatgaagagaattgcagtttatgctcagcctatcatcagcaaa gccagaccagatctgctgaaaactcactttattccaacactggagaaattgaagaagaaa gctataaagattgtgatggaagaggagcaactgaaagcagacagtaaaactgacacccag gaagctgagctactcattcttgatgaatttgctgttctttgtagagatctctacgccttc tatccaatgttgatacgttatgtagacaacaacagagccaattggctaaagaaaccagat gcagactctgatgaactcttccgaatggtagctgaagtgtttatcctgtggtgtaaatca cataatttcaaaagagaagaacaaaattttgtgattcagaatgaaatcaacaacttggca tttttaacaggagataccaaaagcaagatgtctaaagccatgcaagtaaagtccggagga caagatcaagaaagaaagaaatcaaaacgtagaggggatttgtactccatacaaacatcc ttgattgtagctgcacttaaaaagatgcttcctattggcttgaatatgtgtactcctgga gatcaagagctcatctctttggctaagactaggtacagccatagggacactgatgaagaa gtcagagagcatttacgtaacaacttacatttgcaggaaaagtctgatgatccagctgtg aaatggcagttaaatctgtataaagacattttgaaaagtgatgagcctactgaccctgag aaaaatgtggaacgtgtgcagaggatatcagctgctctgtatcatctggagcaggttgaa caaccactgagatcaaagaaagctgtttggcataaactcctgtcaaaacaacgcaaaagg gctgttgttgcttgttttagaatggcaccattgtacaacctgcccaggcaccgttctatt aacctcttcctccatggctatcagaactattggatagaaacagaggaatattcatttgag gagaaactagttcaggatttggctaaacctccaaaaaaagatgaagaagaagaggaagat actgagaaaaaacagcctgatccacttcatcagattatcctttattttagtcgcaatgct ctcacagagaggagcaaactagaagatgatcctttatatatcgcctattctgccatgatg gcaaagagctgtcaggaagaagaggaggaagaagaggaagaaaaagagaagacatttgag gagaaagaaatggaaaagcagagaactctttaccagcaagctcgcttgcatgatcgtgga gctgctgagatggtccttcagatgattagtgcaagcaaaggtcatacaggacccatggtt gttgaaacattaaaacttggtattgctattctaaatggtgggaataccatagttcaacag aaaatgttagactacctgaaggagaaaaaggatgctggattctttcaaagtctctctggc ttgatgcagtcctgcagtgttcttgacttgaatgcgtttgagagacaaaataaagcagaa ggcctgggaatggttactgaagaaggaactctcatcgttcgtgagcgtggtgaaaaagtg ttgcagcatgatgaatttactcgagatctatttagatttttacaactgctctgtgaaggg cataacaatgattttcaaaattacctacgtactcagatgggcaacaccacaacagtgaat attatcattagtactgttgactatctcttgcgtcttcaggaatcaatcagtgacttttat tggtactattcaggaaaagatgtcattgatgaatcaggacaacgtaacttctctaaagct ttggctgtcaccaaacaaatattcaattcccttacagaatatattcagggcccttgcata ggtaaccaacaaagtctggctcatagtaggctgtgggatgcagttgttggctttcttcat gtctttgccaatatgcagatgaaactttcacaggactctgctcagattgaattgcttaaa gaactgctagatctactaaaggatatggtagtcatgctgttgtcactgcttgaaggtaat gttgtaaacggaacgatcggaaaacaaatggtcgatacgcttgtagaatcatctagcaat gtagaattgattttgaaattttttgacatgttcctcaaattaaaagatctaactaattca gatgctttcaaagaacatgacccagatggtaaaggcataatttcaaaaaaggaattccag aagtcaatggaggctcaaaaacaatatatacagtcagagattgaattccttctatcctgt gcagaagctgatgaaaatgacatgtttaactatgtcgattttgtggaaagattccatgaa ccagccaaagacattggatttaatgtagcagtactgctaacaaacctttcagaacacatg cctaacgattcacgccttcagagcctacttgaacctgcagaaagtgttcttaattacttt gaaccataccttggccgtattgaaataatgggtggagccaagaaaatagaaagagtttac tttgaaatcagtgagtccagtagaatgcagtgggagaagccacaggtgaaggaatccaaa aggcagttcatatttgatgttgtaaatgaaggtggagagcaagaaaagatggaactcttt gtgaatttctgtgaagacacaatctttgaaatgcagttagcatcacagatctctgaaact gattcagctgagaggcctgaggaagaggaagaagagtcttgctatgttgtagatattgga gatgatgaggaagaagaaaagtccctggaatctccttcagcttttgcaatggcctgtgct gcagtgaagaagaatgttaccaacttttttaaaatggtcactgtgaagaacctaagaaaa cagtacaggaaagttagaaagatgacagtaaaagaaatggtgaaagtgtttttctccttt ttctggatcctatttgtagggatgttccaactgttctttactatagtgtggggaattttc cagattctttggagcactgtatttgggggtggcctggttgaaggagccaaaaacattaaa gtcactaaaatattaggggacatgcctgacccaacacagtttggaatccatgatgatgtt acagaagcagaaaaagctgaaggtgctgagcatggcattcgagctgaacttgtccagttt gtaaagggcgaaaaggcagaaactgacattatctctgatatttttggcattccaaccaaa aaagaaggtggctcaaaacatggtcatgatgctggacttggggatattgcagaaatgctt ggttctgatatccagtcttctttggaaaacacagttcgtaagaaaaaaggattacagcta tctgaaattgcaaaagaagctgaagcagaaagaaaagtggaagctgagaaggctgacatg gaagatggtgagaaacaagataaagcaaaggaagtactgtccgagcagctggaagaggga aaggtgaagaaaaagaagagaaggcatggacaaaaaattgagaaacctgaggctgttatg gctaacttcttcaaagctttggaaatttatcaaacaaaaatgcttcactacctagcaaga aatttttataacttaaggtttcttgctctatttgttgcatttgctatcaactttattcta ctattttacaaggtgacagaagagccacttgatgaggtagaggaagactctaatctctgg aacacttttgatgaagaggaagaggaggaaggcatggtgttttttgttttagaagaaagt acaggttacatggcacccgctctcagagcattggcagttattcatactatcatctccttt gtctgtgtgatcggatactattgcttaaaggtccctctggttgtattcaagagagaaaag gaagtagctaggaagctggaatttgatggattatacataactgaacagccatctgaagat gatattaaaggacaatgggatcgcctggttataaacacaccgtcctttcctaacaattac tgggacaaatttgtaaaacggaaggttattaacaagtatggagacttatatggagcagag cgcatagcagaacttttgggtttggacaaaaatgcccttgattttagtccagtggaagag agtgaaccagaagaggcatctcttctatcatggttaagctccattgataccaagtaccac atttggaagctcggtgttgttttcactgataattcatttttatacttagcttggtacaca actatgtctatccttgggcactacaacaacttcttctttgctgctcatctgctggatatt gctatgggtttcaagactctgcgaaccattctgtcttcagtcactcacaatggcaaacag cttgtgcttactgtaggactcctggctgtagtagtgtatctttataccgttgtggcgttc aactttttccgcaaattctacaacaaaagtgaagatgaagatgaaccagacatgaaatgt gatgacatgatgacgtgttacctgttccacatgtatgtgggtgtaagagctggtggtggc attggggatgaaattgaggatcctgcaggagacccttatgaaatgtatcgaattgtcttt gacatcacatttttcttctttgtcattgttatcctactggccattattcaaggtctgatc attgatgcttttggtgaattaagagaccagcaagaacaagtgagagaagatatggagacc aaatgttttatttgtggaattggcaacgactattttgacacaaccccacatggctttgaa acgcatactttgcaagagcacaacttggcaaactacctgttctttttaatgtatctcata aacaaggatgaaactgagcatactggccaggaatcatttgtgtggaagatgtaccaagaa agatgttgggattttttcccagcaggagactgcttccggaaacagtatgaggatcaactt ggctaa

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